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Aliases for SPATA45 Gene

Aliases for SPATA45 Gene

  • Spermatogenesis Associated 45 2 3 5
  • C1orf227 3 4
  • Chromosome 1 Open Reading Frame 227 2
  • UPF0732 Protein C1orf227 3

External Ids for SPATA45 Gene

Previous HGNC Symbols for SPATA45 Gene

  • C1orf227

Previous GeneCards Identifiers for SPATA45 Gene

  • GC01M213004

Summaries for SPATA45 Gene

GeneCards Summary for SPATA45 Gene

SPATA45 (Spermatogenesis Associated 45) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPATA45 Gene

Genomics for SPATA45 Gene

Regulatory Elements for SPATA45 Gene

Enhancers for SPATA45 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around SPATA45 on UCSC Golden Path with GeneCards custom track

Genomic Location for SPATA45 Gene

212,830,141 bp from pter
212,847,649 bp from pter
17,509 bases
Minus strand

Genomic View for SPATA45 Gene

Genes around SPATA45 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SPATA45 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SPATA45 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPATA45 Gene

Proteins for SPATA45 Gene

  • Protein details for SPATA45 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Spermatogenesis-associated protein 45
    Protein Accession:

    Protein attributes for SPATA45 Gene

    98 amino acids
    Molecular mass:
    11356 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SPATA45 Gene

Proteomics data for SPATA45 Gene at MOPED

Post-translational modifications for SPATA45 Gene

No Post-translational modifications

Other Protein References for SPATA45 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SPATA45 Gene

Domains & Families for SPATA45 Gene

Protein Domains for SPATA45 Gene


Suggested Antigen Peptide Sequences for SPATA45 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the SPATA45 family.
  • Belongs to the SPATA45 family.
genes like me logo Genes that share domains with SPATA45: view

No data available for Gene Families for SPATA45 Gene

Function for SPATA45 Gene

genes like me logo Genes that share phenotypes with SPATA45: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SPATA45 Gene

Localization for SPATA45 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SPATA45 Gene

Pathways & Interactions for SPATA45 Gene

SuperPathways for SPATA45 Gene

No Data Available

Interacting Proteins for SPATA45 Gene

Gene Ontology (GO) - Biological Process for SPATA45 Gene


No data available for Pathways by source and SIGNOR curated interactions for SPATA45 Gene

Drugs & Compounds for SPATA45 Gene

No Compound Related Data Available

Transcripts for SPATA45 Gene

mRNA/cDNA for SPATA45 Gene

(1) REFSEQ mRNAs :
(6) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SPATA45 Gene

No ASD Table

Relevant External Links for SPATA45 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SPATA45 Gene

mRNA expression in normal human tissues for SPATA45 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SPATA45 Gene

This gene is overexpressed in Testis (x28.5).
genes like me logo Genes that share expression patterns with SPATA45: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SPATA45 Gene

Orthologs for SPATA45 Gene

This gene was present in the common ancestor of mammals.

Orthologs for SPATA45 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SPATA45 35
  • 83.16 (n)
  • 72.16 (a)
C16H1orf227 36
  • 71 (a)
(Canis familiaris)
Mammalia SPATA45 35
  • 82.65 (n)
  • 72.45 (a)
(Mus musculus)
Mammalia 1700022P22Rik 35
  • 73.2 (n)
  • 58.76 (a)
Spata45 16
1700022P22Rik 36
  • 59 (a)
(Pan troglodytes)
Mammalia SPATA45 35
  • 98.98 (n)
  • 97.96 (a)
-- 36
  • 98 (a)
-- 36
  • 98 (a)
(Rattus norvegicus)
Mammalia LOC498316 35
  • 72.16 (n)
  • 62.89 (a)
Species with no ortholog for SPATA45:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SPATA45 Gene

Gene Tree for SPATA45 (if available)
Gene Tree for SPATA45 (if available)

Paralogs for SPATA45 Gene

No data available for Paralogs for SPATA45 Gene

Variants for SPATA45 Gene

Sequence variations from dbSNP and Humsavar for SPATA45 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs10864004 - 212,836,127(+) TTTCA(A/G)TGGTT reference, missense
rs2172981 -- 212,842,953(+) ttagc(C/T)gggcg intron-variant
rs2487264 -- 212,847,362(+) TTTTG(C/T)GCCAT intron-variant
rs2359327 -- 212,842,898(+) cctgg(C/G)taaca intron-variant
rs2497959 -- 212,847,534(-) TTCTC(A/G)TACAG intron-variant

Variation tolerance for SPATA45 Gene

Residual Variation Intolerance Score: 60.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.84; 58.65% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for SPATA45 Gene

Disorders for SPATA45 Gene

Relevant External Links for SPATA45

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SPATA45 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SPATA45 Gene

Publications for SPATA45 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for SPATA45 Gene

Sources for SPATA45 Gene