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Aliases for SPATA32 Gene

Aliases for SPATA32 Gene

  • Spermatogenesis Associated 32 2 3 5
  • Testis-Expressed Sequence 34 Protein 3 4
  • Acrosome Expressed 2 2 3
  • Testis Expressed 34 2 3
  • C17orf46 3 4
  • TEX34 3 4
  • Chromosome 17 Open Reading Frame 46 2
  • CTD-2020K17.4 3
  • VAD1.2 3
  • AEP2 3

External Ids for SPATA32 Gene

Previous HGNC Symbols for SPATA32 Gene

  • C17orf46
  • TEX34

Previous GeneCards Identifiers for SPATA32 Gene

  • GC17M043333

Summaries for SPATA32 Gene

GeneCards Summary for SPATA32 Gene

SPATA32 (Spermatogenesis Associated 32) is a Protein Coding gene. GO annotations related to this gene include actin binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPATA32 Gene

Genomics for SPATA32 Gene

Regulatory Elements for SPATA32 Gene

Promoters for SPATA32 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around SPATA32 on UCSC Golden Path with GeneCards custom track

Genomic Location for SPATA32 Gene

Chromosome:
17
Start:
45,247,274 bp from pter
End:
45,262,112 bp from pter
Size:
14,839 bases
Orientation:
Minus strand

Genomic View for SPATA32 Gene

Genes around SPATA32 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SPATA32 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SPATA32 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPATA32 Gene

Proteins for SPATA32 Gene

  • Protein details for SPATA32 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96LK8-SPT32_HUMAN
    Recommended name:
    Spermatogenesis-associated protein 32
    Protein Accession:
    Q96LK8
    Secondary Accessions:
    • Q7Z4U1
    • Q8N6V6

    Protein attributes for SPATA32 Gene

    Size:
    384 amino acids
    Molecular mass:
    42325 Da
    Quaternary structure:
    • Interacts with syntaxin-1 and ACTB.

neXtProt entry for SPATA32 Gene

Proteomics data for SPATA32 Gene at MOPED

Post-translational modifications for SPATA32 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SPATA32 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SPATA32 Gene

Domains & Families for SPATA32 Gene

Protein Domains for SPATA32 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for SPATA32 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SPATA32: view

No data available for Gene Families and UniProtKB/Swiss-Prot for SPATA32 Gene

Function for SPATA32 Gene

genes like me logo Genes that share phenotypes with SPATA32: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SPATA32 Gene

Localization for SPATA32 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SPATA32 Gene COMPARTMENTS Subcellular localization image for SPATA32 gene
Compartment Confidence
nucleus 3
mitochondrion 2
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for SPATA32 Gene

Pathways & Interactions for SPATA32 Gene

SuperPathways for SPATA32 Gene

No Data Available

Interacting Proteins for SPATA32 Gene

Gene Ontology (GO) - Biological Process for SPATA32 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SPATA32 Gene

Drugs & Compounds for SPATA32 Gene

No Compound Related Data Available

Transcripts for SPATA32 Gene

mRNA/cDNA for SPATA32 Gene

(3) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(13) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SPATA32 Gene

Spermatogenesis associated 32:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SPATA32 Gene

No ASD Table

Relevant External Links for SPATA32 Gene

GeneLoc Exon Structure for
SPATA32
ECgene alternative splicing isoforms for
SPATA32

Expression for SPATA32 Gene

mRNA expression in normal human tissues for SPATA32 Gene

mRNA differential expression in normal tissues according to GTEx for SPATA32 Gene

This gene is overexpressed in Testis (x46.0).

SOURCE GeneReport for Unigene cluster for SPATA32 Gene Hs.412719

mRNA Expression by UniProt/SwissProt for SPATA32 Gene

Q96LK8-SPT32_HUMAN
Tissue specificity: Detected in testis, and on the acrosomal cap of spermatids.
genes like me logo Genes that share expression patterns with SPATA32: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for SPATA32 Gene

Orthologs for SPATA32 Gene

This gene was present in the common ancestor of mammals.

Orthologs for SPATA32 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SPATA32 35
  • 98.78 (n)
  • 97.64 (a)
SPATA32 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SPATA32 36
  • 42 (a)
OneToOne
LOC767871 35
  • 65.89 (n)
  • 45.48 (a)
dog
(Canis familiaris)
Mammalia SPATA32 36
  • 46 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Spata32 36
  • 41 (a)
OneToOne
Spata32 16
Spata32 35
  • 61.68 (n)
  • 44.9 (a)
rat
(Rattus norvegicus)
Mammalia Spata32 35
  • 60.96 (n)
  • 43.24 (a)
Species with no ortholog for SPATA32:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SPATA32 Gene

ENSEMBL:
Gene Tree for SPATA32 (if available)
TreeFam:
Gene Tree for SPATA32 (if available)

Paralogs for SPATA32 Gene

No data available for Paralogs for SPATA32 Gene

Variants for SPATA32 Gene

Sequence variations from dbSNP and Humsavar for SPATA32 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
VAR_060279 -

Variation tolerance for SPATA32 Gene

Residual Variation Intolerance Score: 69.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.10; 69.08% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SPATA32 Gene

HapMap Linkage Disequilibrium report
SPATA32
Human Gene Mutation Database (HGMD)
SPATA32

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SPATA32 Gene

Disorders for SPATA32 Gene

Relevant External Links for SPATA32

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SPATA32

No disorders were found for SPATA32 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SPATA32 Gene

Publications for SPATA32 Gene

  1. Characterization of an acrosome protein VAD1.2/AEP2 which is differentially expressed in spermatogenesis. (PMID: 18621766) Lee K.F. … Luk J.M. (Mol. Hum. Reprod. 2008) 2 3 4 67
  2. Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph. (PMID: 21048031) Casabonne D. … de Sanjose S. (Haematologica 2011) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PMID: 15342556) Suzuki Y. … Sugano S. (Genome Res. 2004) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3

Products for SPATA32 Gene

Sources for SPATA32 Gene

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