Free for academic non-profit institutions. Other users need a Commercial license

Aliases for SPATA31D1 Gene

Aliases for SPATA31D1 Gene

  • SPATA31 Subfamily D Member 1 2 3 5
  • Family With Sequence Similarity 75, Member D1 2 3
  • Protein FAM75D1 3 4
  • FAM75D1 3 4
  • Spermatogenesis-Associated Protein 31D1 3
  • FAM75-Like Protein FLJ46321 3

External Ids for SPATA31D1 Gene

Previous HGNC Symbols for SPATA31D1 Gene

  • FAM75D1

Previous GeneCards Identifiers for SPATA31D1 Gene

  • GC09P084624
  • GC09P084630
  • GC09P084636
  • GC09P081988
  • GC09P081989
  • GC09P082017

Summaries for SPATA31D1 Gene

GeneCards Summary for SPATA31D1 Gene

SPATA31D1 (SPATA31 Subfamily D Member 1) is a Protein Coding gene. An important paralog of this gene is SPATA31D4.

UniProtKB/Swiss-Prot for SPATA31D1 Gene

  • May play a role in spermatogenesis.

Additional gene information for SPATA31D1 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPATA31D1 Gene

Genomics for SPATA31D1 Gene

Regulatory Elements for SPATA31D1 Gene

Enhancers for SPATA31D1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09H082923 1 ENCODE 9.8 +935.9 935854 0 PKNOX1 ARNT FEZF1 GLI4 ZNF2 ZNF302 FOS KLF7 SP3 REST ENSG00000232749 MTCO3P40 LOC442427 ENSG00000225085 ENSG00000235377 DDX10P2 SPATA31D3 SPATA31D4 SPATA31D2P LOC105376108
GH09H081757 0.3 FANTOM5 10.7 -230.6 -230624 0 RNU6-1035P SPATA31D1 PIR57965 GC09P081823
GH09H082457 0.3 FANTOM5 8.4 +469.6 469617 0 SPATA31D1 ENSG00000232749 LOC105376110
GH09H082374 0.3 FANTOM5 6.7 +386.5 386515 0 SPATA31D1 GC09P082363 GC09P082386
GH09H082274 0.3 FANTOM5 5.5 +286.5 286549 0 SPATA31D1 PIR37439 PIR31661 GC09P082261 GC09P082260 GC09P082259 GC09P082258 GC09P082257
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SPATA31D1 on UCSC Golden Path with GeneCards custom track

Genomic Location for SPATA31D1 Gene

Chromosome:
9
Start:
81,987,667 bp from pter
End:
81,995,256 bp from pter
Size:
7,590 bases
Orientation:
Plus strand

Genomic View for SPATA31D1 Gene

Genes around SPATA31D1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SPATA31D1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SPATA31D1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPATA31D1 Gene

Proteins for SPATA31D1 Gene

  • Protein details for SPATA31D1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZQQ2-S31D1_HUMAN
    Recommended name:
    Spermatogenesis-associated protein 31D1
    Protein Accession:
    Q6ZQQ2

    Protein attributes for SPATA31D1 Gene

    Size:
    1576 amino acids
    Molecular mass:
    175618 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SPATA31D1 Gene

Post-translational modifications for SPATA31D1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SPATA31D1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SPATA31D1 Gene

Domains & Families for SPATA31D1 Gene

Gene Families for SPATA31D1 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for SPATA31D1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for SPATA31D1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6ZQQ2

UniProtKB/Swiss-Prot:

S31D1_HUMAN :
  • Belongs to the SPATA31 family.
Family:
  • Belongs to the SPATA31 family.
genes like me logo Genes that share domains with SPATA31D1: view

Function for SPATA31D1 Gene

Molecular function for SPATA31D1 Gene

UniProtKB/Swiss-Prot Function:
May play a role in spermatogenesis.

Phenotypes From GWAS Catalog for SPATA31D1 Gene

Phenotypes for SPATA31D1 Gene

genes like me logo Genes that share phenotypes with SPATA31D1: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for SPATA31D1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SPATA31D1 Gene

Localization for SPATA31D1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SPATA31D1 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SPATA31D1 gene
Compartment Confidence
plasma membrane 3
nucleus 2
cytosol 1

Gene Ontology (GO) - Cellular Components for SPATA31D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SPATA31D1: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for SPATA31D1 Gene

Pathways & Interactions for SPATA31D1 Gene

SuperPathways for SPATA31D1 Gene

No Data Available

Interacting Proteins for SPATA31D1 Gene

Gene Ontology (GO) - Biological Process for SPATA31D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007283 spermatogenesis IEA --
GO:0030154 cell differentiation IEA --
genes like me logo Genes that share ontologies with SPATA31D1: view

No data available for Pathways by source and SIGNOR curated interactions for SPATA31D1 Gene

Drugs & Compounds for SPATA31D1 Gene

No Compound Related Data Available

Transcripts for SPATA31D1 Gene

mRNA/cDNA for SPATA31D1 Gene

(2) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(10) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SPATA31D1 Gene

SPATA31 subfamily D, member 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for SPATA31D1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for SPATA31D1 Gene

No ASD Table

Relevant External Links for SPATA31D1 Gene

GeneLoc Exon Structure for
SPATA31D1
ECgene alternative splicing isoforms for
SPATA31D1

Expression for SPATA31D1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SPATA31D1 Gene

mRNA differential expression in normal tissues according to GTEx for SPATA31D1 Gene

This gene is overexpressed in Testis (x51.4).

Protein differential expression in normal tissues from HIPED for SPATA31D1 Gene

This gene is overexpressed in Monocytes (59.0) and Neutrophil (6.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SPATA31D1 Gene



Protein tissue co-expression partners for SPATA31D1 Gene

NURSA nuclear receptor signaling pathways regulating expression of SPATA31D1 Gene:

SPATA31D1

SOURCE GeneReport for Unigene cluster for SPATA31D1 Gene:

Hs.209545
genes like me logo Genes that share expression patterns with SPATA31D1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SPATA31D1 Gene

Orthologs for SPATA31D1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for SPATA31D1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SPATA31D1 34
  • 97 (a)
OneToOne
LOC100609070 33
  • 95.43 (n)
cow
(Bos Taurus)
Mammalia LOC782251 33
  • 72.3 (n)
SPATA31D1 34
  • 53 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM75D1 33
  • 68.94 (n)
-- 34
  • 49 (a)
OneToMany
-- 34
  • 48 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Spata31d1a 33 34
  • 57 (n)
Spata31d1c 34
  • 35 (a)
OneToMany
Spata31d1b 34
  • 31 (a)
OneToMany
Spata31d1d 34
  • 31 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Spata31d3 33
  • 56.49 (n)
Species where no ortholog for SPATA31D1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SPATA31D1 Gene

ENSEMBL:
Gene Tree for SPATA31D1 (if available)
TreeFam:
Gene Tree for SPATA31D1 (if available)

Paralogs for SPATA31D1 Gene

(2) SIMAP similar genes for SPATA31D1 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for SPATA31D1 Gene

genes like me logo Genes that share paralogs with SPATA31D1: view

Variants for SPATA31D1 Gene

Sequence variations from dbSNP and Humsavar for SPATA31D1 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1000657091 -- 81,987,927(+) GCCCA(A/T)ATTTC intron-variant, upstream-variant-2KB
rs1000675618 -- 81,987,549(+) GTATG(G/T)GTGTT intron-variant, upstream-variant-2KB, reference, missense
rs1000735265 -- 81,992,608(+) ATTGC(C/T)ACGTC intron-variant, reference, missense
rs1003520806 -- 81,986,193(+) GTGAG(A/G)TTGCT intron-variant, upstream-variant-2KB
rs1003658107 -- 81,985,825(+) TGACT(A/G)TTAAG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SPATA31D1 Gene

Variant ID Type Subtype PubMed ID
nsv6584 CNV deletion 18451855
nsv821665 CNV loss 15273396
nsv831639 CNV loss 17160897
nsv8537 CNV loss 18304495
nsv968711 CNV duplication 23825009

Variation tolerance for SPATA31D1 Gene

Residual Variation Intolerance Score: 86.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.86; 67.36% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SPATA31D1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SPATA31D1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SPATA31D1 Gene

Disorders for SPATA31D1 Gene

Relevant External Links for SPATA31D1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SPATA31D1

No disorders were found for SPATA31D1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SPATA31D1 Gene

Publications for SPATA31D1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4 60

Products for SPATA31D1 Gene

Sources for SPATA31D1 Gene

Content
Loading form....