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Aliases for SPATA31A7 Gene

Aliases for SPATA31A7 Gene

  • SPATA31 Subfamily A, Member 7 2 3 5
  • Family With Sequence Similarity 75, Member A7 2 3
  • Family With Sequence Similarity 75, Member A4 2 3
  • SPATA31 Subfamily A, Member 4 2 3
  • Protein FAM75A7 3 4
  • SPATA31A4 3 4
  • FAM75A4 3 4
  • FAM75A7 3 4
  • Spermatogenesis-Associated Protein 31A4 3
  • Protein FAM75A4 3
  • C9orf36A 3
  • AEP1 3

External Ids for SPATA31A7 Gene

Previous HGNC Symbols for SPATA31A7 Gene

  • FAM75A7
  • SPATA31A4
  • FAM75A4

Previous GeneCards Identifiers for SPATA31A7 Gene

  • GC09M065504

Summaries for SPATA31A7 Gene

GeneCards Summary for SPATA31A7 Gene

SPATA31A7 (SPATA31 Subfamily A, Member 7) is a Protein Coding gene. An important paralog of this gene is SPATA31A1.

UniProtKB/Swiss-Prot for SPATA31A7 Gene

  • May play a role in spermatogenesis.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPATA31A7 Gene

Genomics for SPATA31A7 Gene

Regulatory Elements for SPATA31A7 Gene

Enhancers for SPATA31A7 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around SPATA31A7 on UCSC Golden Path with GeneCards custom track

Genomic Location for SPATA31A7 Gene

Chromosome:
9
Start:
61,190,003 bp from pter
End:
61,196,280 bp from pter
Size:
6,278 bases
Orientation:
Plus strand

Genomic View for SPATA31A7 Gene

Genes around SPATA31A7 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SPATA31A7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SPATA31A7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPATA31A7 Gene

Proteins for SPATA31A7 Gene

  • Protein details for SPATA31A7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IWB4-S31A7_HUMAN
    Recommended name:
    Spermatogenesis-associated protein 31A7
    Protein Accession:
    Q8IWB4
    Secondary Accessions:
    • Q4VX67
    • Q5TZK4
    • Q9Y4Q5

    Protein attributes for SPATA31A7 Gene

    Size:
    1347 amino acids
    Molecular mass:
    148734 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH40528.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for SPATA31A7 Gene

Proteomics data for SPATA31A7 Gene at MOPED

Post-translational modifications for SPATA31A7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SPATA31A7 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SPATA31A7 Gene

Domains & Families for SPATA31A7 Gene

Protein Domains for SPATA31A7 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for SPATA31A7 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8IWB4

UniProtKB/Swiss-Prot:

S31A7_HUMAN :
  • Belongs to the SPATA31 family.
Family:
  • Belongs to the SPATA31 family.
genes like me logo Genes that share domains with SPATA31A7: view

No data available for Gene Families for SPATA31A7 Gene

Function for SPATA31A7 Gene

Molecular function for SPATA31A7 Gene

UniProtKB/Swiss-Prot Function:
May play a role in spermatogenesis.

Phenotypes for SPATA31A7 Gene

GenomeRNAi human phenotypes for SPATA31A7:
genes like me logo Genes that share phenotypes with SPATA31A7: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SPATA31A7 Gene

Localization for SPATA31A7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SPATA31A7 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SPATA31A7 Gene COMPARTMENTS Subcellular localization image for SPATA31A7 gene
Compartment Confidence
plasma membrane 2
cytosol 1
extracellular 1
nucleus 1

No data available for Gene Ontology (GO) - Cellular Components for SPATA31A7 Gene

Pathways & Interactions for SPATA31A7 Gene

SuperPathways for SPATA31A7 Gene

No Data Available

Interacting Proteins for SPATA31A7 Gene

Selected Interacting proteins: Q8IWB4-S31A7_HUMAN for SPATA31A7 Gene via I2D

Symbol External ID(s) Details
ALB

Gene Ontology (GO) - Biological Process for SPATA31A7 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SPATA31A7 Gene

Drugs & Compounds for SPATA31A7 Gene

No Compound Related Data Available

Transcripts for SPATA31A7 Gene

mRNA/cDNA for SPATA31A7 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(8) Selected AceView cDNA sequences:
(9) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SPATA31A7 Gene

SPATA31 subfamily A, member 7:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SPATA31A7 Gene

No ASD Table

Relevant External Links for SPATA31A7 Gene

GeneLoc Exon Structure for
SPATA31A7
ECgene alternative splicing isoforms for
SPATA31A7

Expression for SPATA31A7 Gene

mRNA expression in normal human tissues for SPATA31A7 Gene

mRNA differential expression in normal tissues according to GTEx for SPATA31A7 Gene

This gene is overexpressed in Testis (x39.6).

SOURCE GeneReport for Unigene cluster for SPATA31A7 Gene Hs.123004

genes like me logo Genes that share expression patterns with SPATA31A7: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SPATA31A7 Gene

Orthologs for SPATA31A7 Gene

This gene was present in the common ancestor of mammals.

Orthologs for SPATA31A7 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia SPATA31A3 35
  • 66.07 (n)
  • 46.54 (a)
dog
(Canis familiaris)
Mammalia SPATA31A3 35
  • 65.44 (n)
  • 46.5 (a)
mouse
(Mus musculus)
Mammalia Spata31 35
  • 58.64 (n)
  • 40.34 (a)
Spata31 16
chimpanzee
(Pan troglodytes)
Mammalia LOC749550 35
  • 98.34 (n)
  • 96.29 (a)
rat
(Rattus norvegicus)
Mammalia Spata31a5 35
  • 59.21 (n)
  • 39.09 (a)
Species with no ortholog for SPATA31A7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SPATA31A7 Gene

ENSEMBL:
Gene Tree for SPATA31A7 (if available)
TreeFam:
Gene Tree for SPATA31A7 (if available)

Paralogs for SPATA31A7 Gene

(10) SIMAP similar genes for SPATA31A7 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SPATA31A7: view

Variants for SPATA31A7 Gene

Sequence variations from dbSNP and Humsavar for SPATA31A7 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs113448023 -- 61,193,208(-) GTGTC(C/T)TGCTC reference, synonymous-codon
rs199542110 -- 61,192,122(-) GAAAG(A/C)AGGTC reference, synonymous-codon
rs199578783 -- 61,192,078(-) ACCAG(C/G/T)TGGAA splice-acceptor-variant
rs199865494 -- 61,194,141(-) TTCAT(A/G)TCCCT reference, synonymous-codon
rs199866705 -- 61,191,534(-) AACTC(C/T)AGTGT intron-variant

Variation tolerance for SPATA31A7 Gene

Gene Damage Index Score: 0.17; 3.92% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for SPATA31A7 Gene

Disorders for SPATA31A7 Gene

Relevant External Links for SPATA31A7

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SPATA31A7

No disorders were found for SPATA31A7 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SPATA31A7 Gene

Publications for SPATA31A7 Gene

  1. The testis-specific VAD1.3/AEP1 interacts with I^-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence. (PMID: 20850414) Zuo Y. … Lee K.F. (Biochem. Biophys. Res. Commun. 2010) 2 3 67
  2. Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex. (PMID: 22952844) Wu Z. … Ma L. (PLoS ONE 2012) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Acrosome-specific gene AEP1: identification, characterization and roles in spermatogenesis. (PMID: 16924657) Luk J.M. … Yeung W.S. (J. Cell. Physiol. 2006) 3
  5. Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry. (PMID: 16094384) Tao W.A. … Aebersold R. (Nat. Methods 2005) 3

Products for SPATA31A7 Gene

Sources for SPATA31A7 Gene

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