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Aliases for SPATA31A6 Gene

Aliases for SPATA31A6 Gene

  • SPATA31 Subfamily A, Member 6 2 3 5
  • Family With Sequence Similarity 75, Member A6 2 3
  • Protein FAM75A6 3 4
  • FAM75A6 3 4

External Ids for SPATA31A6 Gene

Previous HGNC Symbols for SPATA31A6 Gene

  • FAM75A6

Previous GeneCards Identifiers for SPATA31A6 Gene

  • GC09M043624

Summaries for SPATA31A6 Gene

GeneCards Summary for SPATA31A6 Gene

SPATA31A6 (SPATA31 Subfamily A, Member 6) is a Protein Coding gene. An important paralog of this gene is SPATA31A1.

UniProtKB/Swiss-Prot for SPATA31A6 Gene

  • May play a role in spermatogenesis.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPATA31A6 Gene

Genomics for SPATA31A6 Gene

Regulatory Elements for SPATA31A6 Gene

Enhancers for SPATA31A6 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around SPATA31A6 on UCSC Golden Path with GeneCards custom track

Genomic Location for SPATA31A6 Gene

42,183,659 bp from pter
42,189,887 bp from pter
6,229 bases
Plus strand

Genomic View for SPATA31A6 Gene

Genes around SPATA31A6 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SPATA31A6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SPATA31A6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPATA31A6 Gene

Proteins for SPATA31A6 Gene

  • Protein details for SPATA31A6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Spermatogenesis-associated protein 31A6
    Protein Accession:

    Protein attributes for SPATA31A6 Gene

    1343 amino acids
    Molecular mass:
    147818 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SPATA31A6 Gene

Proteomics data for SPATA31A6 Gene at MOPED

Post-translational modifications for SPATA31A6 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SPATA31A6 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SPATA31A6 Gene

Domains & Families for SPATA31A6 Gene

Protein Domains for SPATA31A6 Gene


Suggested Antigen Peptide Sequences for SPATA31A6 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the SPATA31 family.
  • Belongs to the SPATA31 family.
genes like me logo Genes that share domains with SPATA31A6: view

No data available for Gene Families for SPATA31A6 Gene

Function for SPATA31A6 Gene

Molecular function for SPATA31A6 Gene

UniProtKB/Swiss-Prot Function:
May play a role in spermatogenesis.

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SPATA31A6 Gene

Localization for SPATA31A6 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SPATA31A6 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for SPATA31A6 Gene COMPARTMENTS Subcellular localization image for SPATA31A6 gene
Compartment Confidence
cytosol 2
plasma membrane 2
golgi apparatus 1
nucleus 1
peroxisome 1

No data available for Gene Ontology (GO) - Cellular Components for SPATA31A6 Gene

Pathways & Interactions for SPATA31A6 Gene

SuperPathways for SPATA31A6 Gene

No Data Available

Interacting Proteins for SPATA31A6 Gene

Gene Ontology (GO) - Biological Process for SPATA31A6 Gene


No data available for Pathways by source and SIGNOR curated interactions for SPATA31A6 Gene

Drugs & Compounds for SPATA31A6 Gene

No Compound Related Data Available

Transcripts for SPATA31A6 Gene

mRNA/cDNA for SPATA31A6 Gene

(2) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SPATA31A6 Gene

SPATA31 subfamily A, member 6:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SPATA31A6 Gene

No ASD Table

Relevant External Links for SPATA31A6 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SPATA31A6 Gene

mRNA expression in normal human tissues for SPATA31A6 Gene

mRNA differential expression in normal tissues according to GTEx for SPATA31A6 Gene

This gene is overexpressed in Testis (x41.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SPATA31A6 Gene

SOURCE GeneReport for Unigene cluster for SPATA31A6 Gene Hs.455299

genes like me logo Genes that share expression patterns with SPATA31A6: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SPATA31A6 Gene

Orthologs for SPATA31A6 Gene

This gene was present in the common ancestor of mammals.

Orthologs for SPATA31A6 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SPATA31A3 35
  • 66.32 (n)
  • 47.22 (a)
-- 36
  • 44 (a)
(Canis familiaris)
Mammalia SPATA31A3 35
  • 66.51 (n)
  • 47.95 (a)
-- 36
  • 45 (a)
(Mus musculus)
Mammalia Spata31 35
  • 58.42 (n)
  • 41.35 (a)
Spata31 36
  • 36 (a)
(Pan troglodytes)
Mammalia LOC749550 35
  • 98.41 (n)
  • 96.65 (a)
-- 36
  • 96 (a)
-- 36
  • 96 (a)
(Rattus norvegicus)
Mammalia Spata31a5 35
  • 59.36 (n)
  • 39.69 (a)
Species with no ortholog for SPATA31A6:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SPATA31A6 Gene

Gene Tree for SPATA31A6 (if available)
Gene Tree for SPATA31A6 (if available)

Paralogs for SPATA31A6 Gene

(10) SIMAP similar genes for SPATA31A6 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SPATA31A6: view

Variants for SPATA31A6 Gene

Sequence variations from dbSNP and Humsavar for SPATA31A6 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs7854889 -- 42,183,188(-) TTTTG(C/T)CTTGT upstream-variant-2KB
rs113485434 -- 42,187,346(-) CCTTC(C/T)AGTTG reference, synonymous-codon
rs113695382 -- 42,188,037(-) GTTCA(C/T)ACAGG reference, missense
rs113824203 -- 42,188,099(-) ACAAT(A/T)TGGGC reference, missense
rs2259625 -- 42,185,802(+) GGGAC(A/G)TGACC intron-variant

Variation tolerance for SPATA31A6 Gene

Gene Damage Index Score: 15.63; 97.26% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for SPATA31A6 Gene

Disorders for SPATA31A6 Gene

Relevant External Links for SPATA31A6

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SPATA31A6 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SPATA31A6 Gene

Publications for SPATA31A6 Gene

  1. The testis-specific VAD1.3/AEP1 interacts with I^-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence. (PMID: 20850414) Zuo Y. … Lee K.F. (Biochem. Biophys. Res. Commun. 2010) 2 3 67

Products for SPATA31A6 Gene

Sources for SPATA31A6 Gene