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Aliases for SPATA31A6 Gene

Aliases for SPATA31A6 Gene

  • SPATA31 Subfamily A, Member 6 2 3
  • Family With Sequence Similarity 75, Member A6 2 3
  • Protein FAM75A6 3 4
  • FAM75A6 3 4

External Ids for SPATA31A6 Gene

Previous HGNC Symbols for SPATA31A6 Gene

  • FAM75A6

Previous GeneCards Identifiers for SPATA31A6 Gene

  • GC09M043624

Summaries for SPATA31A6 Gene

GeneCards Summary for SPATA31A6 Gene

SPATA31A6 (SPATA31 Subfamily A, Member 6) is a Protein Coding gene. An important paralog of this gene is SPATA31A1.

UniProtKB/Swiss-Prot for SPATA31A6 Gene

  • May play a role in spermatogenesis.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPATA31A6 Gene

Genomics for SPATA31A6 Gene

Genomic Location for SPATA31A6 Gene

42,183,659 bp from pter
42,189,887 bp from pter
6,229 bases
Plus strand

Genomic View for SPATA31A6 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SPATA31A6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPATA31A6 Gene

No data available for Regulatory Elements for SPATA31A6 Gene

Proteins for SPATA31A6 Gene

  • Protein details for SPATA31A6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Spermatogenesis-associated protein 31A6
    Protein Accession:

    Protein attributes for SPATA31A6 Gene

    1343 amino acids
    Molecular mass:
    147818 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SPATA31A6 Gene

Proteomics data for SPATA31A6 Gene at MOPED

Post-translational modifications for SPATA31A6 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SPATA31A6 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SPATA31A6 Gene

Domains & Families for SPATA31A6 Gene

Protein Domains for SPATA31A6 Gene


Suggested Antigen Peptide Sequences for SPATA31A6 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the SPATA31 family.
  • Belongs to the SPATA31 family.
genes like me logo Genes that share domains with SPATA31A6: view

No data available for Gene Families for SPATA31A6 Gene

Function for SPATA31A6 Gene

Molecular function for SPATA31A6 Gene

UniProtKB/Swiss-Prot Function:
May play a role in spermatogenesis.

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SPATA31A6 Gene

Localization for SPATA31A6 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SPATA31A6 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SPATA31A6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SPATA31A6: view

No data available for Subcellular locations from COMPARTMENTS for SPATA31A6 Gene

Pathways & Interactions for SPATA31A6 Gene

SuperPathways for SPATA31A6 Gene

No Data Available

Interacting Proteins for SPATA31A6 Gene

Gene Ontology (GO) - Biological Process for SPATA31A6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007283 spermatogenesis IEA --
GO:0030154 cell differentiation IEA --
genes like me logo Genes that share ontologies with SPATA31A6: view

No data available for Pathways by source and SIGNOR curated interactions for SPATA31A6 Gene

Drugs & Compounds for SPATA31A6 Gene

No Compound Related Data Available

Transcripts for SPATA31A6 Gene

mRNA/cDNA for SPATA31A6 Gene

(2) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SPATA31A6 Gene

SPATA31 subfamily A, member 6:
Representative Sequences:

CRISPR Products

miRNA Products

  • QIAGEN qRT-PCR Assays for microRNAs that regulate SPATA31A6
    • Block miRNA regulation of SPATA31A6 using miScript Target Protectors

    Inhibitory RNA Products

    • Predesigned siRNA for gene silencing in human,mouse,rat for SPATA31A6

    Flow Cytometry Products

    Alternative Splicing Database (ASD) splice patterns (SP) for SPATA31A6 Gene

    No ASD Table

    Relevant External Links for SPATA31A6 Gene

    GeneLoc Exon Structure for
    ECgene alternative splicing isoforms for

    Expression for SPATA31A6 Gene

    mRNA expression in normal human tissues for SPATA31A6 Gene

    mRNA differential expression in normal tissues according to GTEx for SPATA31A6 Gene

    This gene is overexpressed in Testis (x41.2).

    Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SPATA31A6 Gene

    SOURCE GeneReport for Unigene cluster for SPATA31A6 Gene Hs.455299

    genes like me logo Genes that share expression patterns with SPATA31A6: view

    Primer Products

    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat

    In Situ Assay Products

    No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SPATA31A6 Gene

    Orthologs for SPATA31A6 Gene

    This gene was present in the common ancestor of mammals.

    Orthologs for SPATA31A6 Gene

    Organism Taxonomy Gene Similarity Type Details
    (Bos Taurus)
    Mammalia SPATA31A3 35
    • 66.32 (n)
    • 47.22 (a)
    -- 36
    • 44 (a)
    (Canis familiaris)
    Mammalia SPATA31A3 35
    • 66.51 (n)
    • 47.95 (a)
    -- 36
    • 45 (a)
    (Mus musculus)
    Mammalia Spata31 35
    • 58.42 (n)
    • 41.35 (a)
    Spata31 36
    • 36 (a)
    (Pan troglodytes)
    Mammalia LOC749550 35
    • 98.41 (n)
    • 96.65 (a)
    -- 36
    • 96 (a)
    -- 36
    • 96 (a)
    (Rattus norvegicus)
    Mammalia Spata31a5 35
    • 59.36 (n)
    • 39.69 (a)
    Species with no ortholog for SPATA31A6:
    • A. gosspyii yeast (Ashbya gossypii)
    • Actinobacteria (Mycobacterium tuberculosis)
    • African clawed frog (Xenopus laevis)
    • African malaria mosquito (Anopheles gambiae)
    • Alicante grape (Vitis vinifera)
    • alpha proteobacteria (Wolbachia pipientis)
    • amoeba (Dictyostelium discoideum)
    • Archea (Pyrococcus horikoshii)
    • baker's yeast (Saccharomyces cerevisiae)
    • barley (Hordeum vulgare)
    • beta proteobacteria (Neisseria meningitidis)
    • bread mold (Neurospora crassa)
    • chicken (Gallus gallus)
    • Chromalveolata (Phytophthora infestans)
    • common water flea (Daphnia pulex)
    • corn (Zea mays)
    • E. coli (Escherichia coli)
    • filamentous fungi (Aspergillus nidulans)
    • Firmicute bacteria (Streptococcus pneumoniae)
    • fission yeast (Schizosaccharomyces pombe)
    • fruit fly (Drosophila melanogaster)
    • green algae (Chlamydomonas reinhardtii)
    • honey bee (Apis mellifera)
    • K. lactis yeast (Kluyveromyces lactis)
    • lizard (Anolis carolinensis)
    • loblloly pine (Pinus taeda)
    • malaria parasite (Plasmodium falciparum)
    • medicago trunc (Medicago Truncatula)
    • moss (Physcomitrella patens)
    • oppossum (Monodelphis domestica)
    • orangutan (Pongo pygmaeus)
    • pig (Sus scrofa)
    • platypus (Ornithorhynchus anatinus)
    • rainbow trout (Oncorhynchus mykiss)
    • rice (Oryza sativa)
    • rice blast fungus (Magnaporthe grisea)
    • schistosome parasite (Schistosoma mansoni)
    • sea anemone (Nematostella vectensis)
    • sea squirt (Ciona intestinalis)
    • sea squirt (Ciona savignyi)
    • sea urchin (Strongylocentrotus purpuratus)
    • sorghum (Sorghum bicolor)
    • soybean (Glycine max)
    • stem rust fungus (Puccinia graminis)
    • sugarcane (Saccharum officinarum)
    • thale cress (Arabidopsis thaliana)
    • tomato (Lycopersicon esculentum)
    • toxoplasmosis (Toxoplasma gondii)
    • Trichoplax (Trichoplax adhaerens)
    • tropical clawed frog (Silurana tropicalis)
    • wheat (Triticum aestivum)
    • worm (Caenorhabditis elegans)
    • zebrafish (Danio rerio)

    Evolution for SPATA31A6 Gene

    Gene Tree for SPATA31A6 (if available)
    Gene Tree for SPATA31A6 (if available)

    Paralogs for SPATA31A6 Gene

    Paralogs for SPATA31A6 Gene

    (10) SIMAP similar genes for SPATA31A6 Gene using alignment to 1 proteins:

    genes like me logo Genes that share paralogs with SPATA31A6: view

    Variants for SPATA31A6 Gene

    Sequence variations from dbSNP and Humsavar for SPATA31A6 Gene

    SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
    rs2808962 -- 42,184,996(+) TTCTC(A/G)CCCTT intron-variant
    rs2808966 -- 42,186,792(+) CTTTG(C/G)GGAAT missense, reference
    rs2808967 -- 42,186,894(+) AGAAG(C/T)GCTCA missense, reference
    rs2808968 -- 42,186,895(+) GAAGT(G/T)CTCAG reference, missense
    rs2808969 -- 42,186,913(+) GCTCT(G/T)GCAGG missense, reference

    Variation tolerance for SPATA31A6 Gene

    Gene Damage Index Score: 15.63; 97.26% of all genes are more intolerant (likely to be disease-causing)

    Relevant External Links for SPATA31A6 Gene

    HapMap Linkage Disequilibrium report

    No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SPATA31A6 Gene

    Disorders for SPATA31A6 Gene

    Relevant External Links for SPATA31A6

    Atlas of Genetics and Cytogenetics in Oncology and Haematology:
    genes like me logo Genes that share disorders with SPATA31A6: view

    No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SPATA31A6 Gene

    Publications for SPATA31A6 Gene

    1. The testis-specific VAD1.3/AEP1 interacts with I^-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence. (PMID: 20850414) Zuo Y. … Lee K.F. (Biochem. Biophys. Res. Commun. 2010) 2 67
    2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 67

    Products for SPATA31A6 Gene

    Sources for SPATA31A6 Gene

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