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Aliases for SPATA31A3 Gene

Aliases for SPATA31A3 Gene

  • SPATA31 Subfamily A, Member 3 2 3
  • Family With Sequence Similarity 75, Member A3 2 3
  • Protein FAM75A3 3 4
  • FAM75A3 3 4

External Ids for SPATA31A3 Gene

Previous HGNC Symbols for SPATA31A3 Gene

  • FAM75A3

Previous GeneCards Identifiers for SPATA31A3 Gene

  • GC09P040700

Summaries for SPATA31A3 Gene

GeneCards Summary for SPATA31A3 Gene

SPATA31A3 (SPATA31 Subfamily A, Member 3) is a Protein Coding gene. An important paralog of this gene is SPATA31A5.

UniProtKB/Swiss-Prot for SPATA31A3 Gene

  • May play a role in spermatogenesis.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPATA31A3 Gene

Genomics for SPATA31A3 Gene

Genomic Location for SPATA31A3 Gene

Chromosome:
9
Start:
66,986,301 bp from pter
End:
66,992,583 bp from pter
Size:
6,283 bases
Orientation:
Minus strand

Genomic View for SPATA31A3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SPATA31A3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPATA31A3 Gene

No data available for Regulatory Elements for SPATA31A3 Gene

Proteins for SPATA31A3 Gene

  • Protein details for SPATA31A3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5VYP0-S31A3_HUMAN
    Recommended name:
    Spermatogenesis-associated protein 31A3
    Protein Accession:
    Q5VYP0

    Protein attributes for SPATA31A3 Gene

    Size:
    1347 amino acids
    Molecular mass:
    148706 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SPATA31A3 Gene

Proteomics data for SPATA31A3 Gene at MOPED

Post-translational modifications for SPATA31A3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SPATA31A3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SPATA31A3 Gene

Domains & Families for SPATA31A3 Gene

Protein Domains for SPATA31A3 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for SPATA31A3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5VYP0

UniProtKB/Swiss-Prot:

S31A3_HUMAN :
  • Belongs to the SPATA31 family.
Family:
  • Belongs to the SPATA31 family.
genes like me logo Genes that share domains with SPATA31A3: view

No data available for Gene Families for SPATA31A3 Gene

Function for SPATA31A3 Gene

Molecular function for SPATA31A3 Gene

UniProtKB/Swiss-Prot Function:
May play a role in spermatogenesis.

Animal Model Products

CRISPR Products

miRNA Products

  • QIAGEN qRT-PCR Assays for microRNAs that regulate SPATA31A3
    • Block miRNA regulation of SPATA31A3 using miScript Target Protectors

    Inhibitory RNA Products

    • Predesigned siRNA for gene silencing in human,mouse,rat for SPATA31A3

    In Situ Assay Products

    Flow Cytometry Products

    No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SPATA31A3 Gene

    Localization for SPATA31A3 Gene

    Subcellular locations from UniProtKB/Swiss-Prot for SPATA31A3 Gene

    Membrane; Single-pass membrane protein.

    Gene Ontology (GO) - Cellular Components for SPATA31A3 Gene

    GO ID Qualified GO term Evidence PubMed IDs
    GO:0016021 integral component of membrane IEA --
    genes like me logo Genes that share ontologies with SPATA31A3: view

    No data available for Subcellular locations from COMPARTMENTS for SPATA31A3 Gene

    Pathways & Interactions for SPATA31A3 Gene

    SuperPathways for SPATA31A3 Gene

    No Data Available

    Interacting Proteins for SPATA31A3 Gene

    Gene Ontology (GO) - Biological Process for SPATA31A3 Gene

    GO ID Qualified GO term Evidence PubMed IDs
    GO:0007283 spermatogenesis IEA --
    GO:0030154 cell differentiation IEA --
    genes like me logo Genes that share ontologies with SPATA31A3: view

    No data available for Pathways by source and SIGNOR curated interactions for SPATA31A3 Gene

    Drugs & Compounds for SPATA31A3 Gene

    No Compound Related Data Available

    Transcripts for SPATA31A3 Gene

    mRNA/cDNA for SPATA31A3 Gene

    (2) REFSEQ mRNAs :
    (1) Additional mRNA sequences :
    (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

    Unigene Clusters for SPATA31A3 Gene

    SPATA31 subfamily A, member 3:
    Representative Sequences:

    CRISPR Products

    miRNA Products

    • QIAGEN qRT-PCR Assays for microRNAs that regulate SPATA31A3
      • Block miRNA regulation of SPATA31A3 using miScript Target Protectors

      Inhibitory RNA Products

      • Predesigned siRNA for gene silencing in human,mouse,rat for SPATA31A3

      Flow Cytometry Products

      Alternative Splicing Database (ASD) splice patterns (SP) for SPATA31A3 Gene

      No ASD Table

      Relevant External Links for SPATA31A3 Gene

      GeneLoc Exon Structure for
      SPATA31A3
      ECgene alternative splicing isoforms for
      SPATA31A3

      Expression for SPATA31A3 Gene

      mRNA expression in normal human tissues for SPATA31A3 Gene

      Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SPATA31A3 Gene



      SOURCE GeneReport for Unigene cluster for SPATA31A3 Gene Hs.632078

      genes like me logo Genes that share expression patterns with SPATA31A3: view

      Primer Products

      • QuantiTect SYBR Green Assays in human,mouse,rat
      • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
      • QuantiFast Probe-based Assays in human,mouse,rat

      In Situ Assay Products

      No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SPATA31A3 Gene

      Orthologs for SPATA31A3 Gene

      This gene was present in the common ancestor of mammals.

      Orthologs for SPATA31A3 Gene

      Organism Taxonomy Gene Similarity Type Details
      cow
      (Bos Taurus)
      Mammalia SPATA31A3 35
      • 66.44 (n)
      • 47.22 (a)
      dog
      (Canis familiaris)
      Mammalia SPATA31A3 35
      • 65.62 (n)
      • 46.89 (a)
      mouse
      (Mus musculus)
      Mammalia Spata31 35
      • 58.79 (n)
      • 40.8 (a)
      chimpanzee
      (Pan troglodytes)
      Mammalia LOC749578 35
      • 98.42 (n)
      • 96.21 (a)
      rat
      (Rattus norvegicus)
      Mammalia Spata31a5 35
      • 59.28 (n)
      • 39.41 (a)
      Species with no ortholog for SPATA31A3:
      • A. gosspyii yeast (Ashbya gossypii)
      • Actinobacteria (Mycobacterium tuberculosis)
      • African clawed frog (Xenopus laevis)
      • African malaria mosquito (Anopheles gambiae)
      • Alicante grape (Vitis vinifera)
      • alpha proteobacteria (Wolbachia pipientis)
      • amoeba (Dictyostelium discoideum)
      • Archea (Pyrococcus horikoshii)
      • baker's yeast (Saccharomyces cerevisiae)
      • barley (Hordeum vulgare)
      • beta proteobacteria (Neisseria meningitidis)
      • bread mold (Neurospora crassa)
      • chicken (Gallus gallus)
      • Chromalveolata (Phytophthora infestans)
      • common water flea (Daphnia pulex)
      • corn (Zea mays)
      • E. coli (Escherichia coli)
      • filamentous fungi (Aspergillus nidulans)
      • Firmicute bacteria (Streptococcus pneumoniae)
      • fission yeast (Schizosaccharomyces pombe)
      • fruit fly (Drosophila melanogaster)
      • green algae (Chlamydomonas reinhardtii)
      • honey bee (Apis mellifera)
      • K. lactis yeast (Kluyveromyces lactis)
      • lizard (Anolis carolinensis)
      • loblloly pine (Pinus taeda)
      • malaria parasite (Plasmodium falciparum)
      • medicago trunc (Medicago Truncatula)
      • moss (Physcomitrella patens)
      • oppossum (Monodelphis domestica)
      • orangutan (Pongo pygmaeus)
      • pig (Sus scrofa)
      • platypus (Ornithorhynchus anatinus)
      • rainbow trout (Oncorhynchus mykiss)
      • rice (Oryza sativa)
      • rice blast fungus (Magnaporthe grisea)
      • schistosome parasite (Schistosoma mansoni)
      • sea anemone (Nematostella vectensis)
      • sea squirt (Ciona intestinalis)
      • sea squirt (Ciona savignyi)
      • sea urchin (Strongylocentrotus purpuratus)
      • sorghum (Sorghum bicolor)
      • soybean (Glycine max)
      • stem rust fungus (Puccinia graminis)
      • sugarcane (Saccharum officinarum)
      • thale cress (Arabidopsis thaliana)
      • tomato (Lycopersicon esculentum)
      • toxoplasmosis (Toxoplasma gondii)
      • Trichoplax (Trichoplax adhaerens)
      • tropical clawed frog (Silurana tropicalis)
      • wheat (Triticum aestivum)
      • worm (Caenorhabditis elegans)
      • zebrafish (Danio rerio)

      Evolution for SPATA31A3 Gene

      ENSEMBL:
      Gene Tree for SPATA31A3 (if available)
      TreeFam:
      Gene Tree for SPATA31A3 (if available)

      Paralogs for SPATA31A3 Gene

      Paralogs for SPATA31A3 Gene

      (11) SIMAP similar genes for SPATA31A3 Gene using alignment to 1 proteins:

      genes like me logo Genes that share paralogs with SPATA31A3: view

      Variants for SPATA31A3 Gene

      Sequence variations from dbSNP and Humsavar for SPATA31A3 Gene

      SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
      rs781630040 -- 66,990,033(-) TCCCC(A/G)GATCC synonymous-codon, reference
      rs781028808 -- 66,993,761(-) TGGGC(-/AG)AGAAT upstream-variant-2KB
      rs781019955 -- 66,987,136(-) AAAAC(A/G)TGAAG reference, missense
      rs760108308 -- 66,987,102(-) CCTCA(A/G)CTTAC reference, synonymous-codon
      rs759856563 -- 66,987,196(-) CCAAA(A/G)GCCAA missense, reference

      Variation tolerance for SPATA31A3 Gene

      Gene Damage Index Score: 5.64; 72.72% of all genes are more intolerant (likely to be disease-causing)

      Relevant External Links for SPATA31A3 Gene

      HapMap Linkage Disequilibrium report
      SPATA31A3

      No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SPATA31A3 Gene

      Disorders for SPATA31A3 Gene

      Relevant External Links for SPATA31A3

      Atlas of Genetics and Cytogenetics in Oncology and Haematology:
      SPATA31A3
      genes like me logo Genes that share disorders with SPATA31A3: view

      No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SPATA31A3 Gene

      Publications for SPATA31A3 Gene

      1. The testis-specific VAD1.3/AEP1 interacts with I^-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence. (PMID: 20850414) Zuo Y. … Lee K.F. (Biochem. Biophys. Res. Commun. 2010) 2 67
      2. p16 Protein and gigaxonin are associated with the ubiquitination of NFI_B in cisplatin-induced senescence of cancer cells. (PMID: 25331947) Veena M.S. … Srivatsan E.S. (J. Biol. Chem. 2014) 67
      3. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 67
      4. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 67
      5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

      Products for SPATA31A3 Gene

      Sources for SPATA31A3 Gene

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