Free for academic non-profit institutions. Other users need a Commercial license

Aliases for SPATA31A3 Gene

Aliases for SPATA31A3 Gene

  • SPATA31 Subfamily A, Member 3 2 3 5
  • Family With Sequence Similarity 75, Member A3 2 3
  • Protein FAM75A3 3 4
  • FAM75A3 3 4

External Ids for SPATA31A3 Gene

Previous HGNC Symbols for SPATA31A3 Gene

  • FAM75A3

Previous GeneCards Identifiers for SPATA31A3 Gene

  • GC09P040700

Summaries for SPATA31A3 Gene

GeneCards Summary for SPATA31A3 Gene

SPATA31A3 (SPATA31 Subfamily A, Member 3) is a Protein Coding gene. An important paralog of this gene is SPATA31A1.

UniProtKB/Swiss-Prot for SPATA31A3 Gene

  • May play a role in spermatogenesis.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPATA31A3 Gene

Genomics for SPATA31A3 Gene

Regulatory Elements for SPATA31A3 Gene

Enhancers for SPATA31A3 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around SPATA31A3 on UCSC Golden Path with GeneCards custom track

Genomic Location for SPATA31A3 Gene

66,986,301 bp from pter
66,992,583 bp from pter
6,283 bases
Minus strand

Genomic View for SPATA31A3 Gene

Genes around SPATA31A3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SPATA31A3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SPATA31A3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPATA31A3 Gene

Proteins for SPATA31A3 Gene

  • Protein details for SPATA31A3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Spermatogenesis-associated protein 31A3
    Protein Accession:

    Protein attributes for SPATA31A3 Gene

    1347 amino acids
    Molecular mass:
    148706 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SPATA31A3 Gene

Proteomics data for SPATA31A3 Gene at MOPED

Post-translational modifications for SPATA31A3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SPATA31A3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SPATA31A3 Gene

Domains & Families for SPATA31A3 Gene

Protein Domains for SPATA31A3 Gene


Suggested Antigen Peptide Sequences for SPATA31A3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the SPATA31 family.
  • Belongs to the SPATA31 family.
genes like me logo Genes that share domains with SPATA31A3: view

No data available for Gene Families for SPATA31A3 Gene

Function for SPATA31A3 Gene

Molecular function for SPATA31A3 Gene

UniProtKB/Swiss-Prot Function:
May play a role in spermatogenesis.

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SPATA31A3 Gene

Localization for SPATA31A3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SPATA31A3 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for SPATA31A3 Gene COMPARTMENTS Subcellular localization image for SPATA31A3 gene
Compartment Confidence
plasma membrane 2
cytosol 1
extracellular 1
nucleus 1

No data available for Gene Ontology (GO) - Cellular Components for SPATA31A3 Gene

Pathways & Interactions for SPATA31A3 Gene

SuperPathways for SPATA31A3 Gene

No Data Available

Interacting Proteins for SPATA31A3 Gene

Gene Ontology (GO) - Biological Process for SPATA31A3 Gene


No data available for Pathways by source and SIGNOR curated interactions for SPATA31A3 Gene

Drugs & Compounds for SPATA31A3 Gene

No Compound Related Data Available

Transcripts for SPATA31A3 Gene

mRNA/cDNA for SPATA31A3 Gene

(2) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SPATA31A3 Gene

SPATA31 subfamily A, member 3:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SPATA31A3 Gene

No ASD Table

Relevant External Links for SPATA31A3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SPATA31A3 Gene

mRNA expression in normal human tissues for SPATA31A3 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SPATA31A3 Gene

SOURCE GeneReport for Unigene cluster for SPATA31A3 Gene Hs.632078

genes like me logo Genes that share expression patterns with SPATA31A3: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SPATA31A3 Gene

Orthologs for SPATA31A3 Gene

This gene was present in the common ancestor of mammals.

Orthologs for SPATA31A3 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SPATA31A3 35
  • 66.44 (n)
  • 47.22 (a)
(Canis familiaris)
Mammalia SPATA31A3 35
  • 65.62 (n)
  • 46.89 (a)
(Mus musculus)
Mammalia Spata31 35
  • 58.79 (n)
  • 40.8 (a)
(Pan troglodytes)
Mammalia LOC749578 35
  • 98.42 (n)
  • 96.21 (a)
(Rattus norvegicus)
Mammalia Spata31a5 35
  • 59.28 (n)
  • 39.41 (a)
Species with no ortholog for SPATA31A3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SPATA31A3 Gene

Gene Tree for SPATA31A3 (if available)
Gene Tree for SPATA31A3 (if available)

Paralogs for SPATA31A3 Gene

(11) SIMAP similar genes for SPATA31A3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SPATA31A3: view

Variants for SPATA31A3 Gene

Sequence variations from dbSNP and Humsavar for SPATA31A3 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs113132795 -- 66,986,143(-) CAAAC(A/G)ACAAA downstream-variant-500B
rs9411670 -- 66,994,416(-) actct(A/G)cagcc upstream-variant-2KB
rs192661010 -- 66,990,081(-) TCTCA(C/G/T)GAGCC reference, synonymous-codon, missense
rs199602513 -- 66,990,127(-) CCCAG(A/G)TGAGG reference, missense
rs199651086 -- 66,987,160(-) GAAGT(C/T)TAGGA reference, missense

Variation tolerance for SPATA31A3 Gene

Gene Damage Index Score: 5.64; 72.72% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for SPATA31A3 Gene

Disorders for SPATA31A3 Gene

Relevant External Links for SPATA31A3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SPATA31A3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SPATA31A3 Gene

Publications for SPATA31A3 Gene

  1. The testis-specific VAD1.3/AEP1 interacts with I^-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence. (PMID: 20850414) Zuo Y. … Lee K.F. (Biochem. Biophys. Res. Commun. 2010) 2 3 67
  2. p16 Protein and gigaxonin are associated with the ubiquitination of NFI_B in cisplatin-induced senescence of cancer cells. (PMID: 25331947) Veena M.S. … Srivatsan E.S. (J. Biol. Chem. 2014) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for SPATA31A3 Gene

Sources for SPATA31A3 Gene