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Aliases for SPATA31A1 Gene

Aliases for SPATA31A1 Gene

  • SPATA31 Subfamily A Member 1 2 3 5
  • Family With Sequence Similarity 75, Member A1 2 3
  • Family With Sequence Similarity 75, Member A2 2 3
  • SPATA31 Subfamily A, Member 2 2 3
  • Protein FAM75A1 3 4
  • SPATA31A2 3 4
  • C9orf36 3 4
  • FAM75A1 3 4
  • FAM75A2 3 4
  • Spermatogenesis-Associated Protein 31A1 3
  • Spermatogenesis-Associated Protein 31A2 3
  • Chromosome 9 Open Reading Frame 36 2
  • Protein FAM75A2 3
  • C9orf36A 3

External Ids for SPATA31A1 Gene

Previous HGNC Symbols for SPATA31A1 Gene

  • C9orf36
  • FAM75A1
  • SPATA31A2
  • FAM75A2

Summaries for SPATA31A1 Gene

GeneCards Summary for SPATA31A1 Gene

SPATA31A1 (SPATA31 Subfamily A Member 1) is a Protein Coding gene. An important paralog of this gene is SPATA31A5.

UniProtKB/Swiss-Prot for SPATA31A1 Gene

  • May play a role in spermatogenesis.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPATA31A1 Gene

Genomics for SPATA31A1 Gene

Genomic Location for SPATA31A1 Gene

39,355,667 bp from pter
39,361,962 bp from pter
6,296 bases
Plus strand

Genomic View for SPATA31A1 Gene

Genes around SPATA31A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SPATA31A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SPATA31A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPATA31A1 Gene

No data available for Regulatory Elements for SPATA31A1 Gene

Proteins for SPATA31A1 Gene

  • Protein details for SPATA31A1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Spermatogenesis-associated protein 31A1
    Protein Accession:
    Secondary Accessions:
    • Q5RGS2

    Protein attributes for SPATA31A1 Gene

    1347 amino acids
    Molecular mass:
    148561 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SPATA31A1 Gene

Post-translational modifications for SPATA31A1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SPATA31A1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SPATA31A1 Gene

Domains & Families for SPATA31A1 Gene

Protein Domains for SPATA31A1 Gene


Suggested Antigen Peptide Sequences for SPATA31A1 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the SPATA31 family.
  • Belongs to the SPATA31 family.
genes like me logo Genes that share domains with SPATA31A1: view

No data available for Gene Families for SPATA31A1 Gene

Function for SPATA31A1 Gene

Molecular function for SPATA31A1 Gene

UniProtKB/Swiss-Prot Function:
May play a role in spermatogenesis.

Phenotypes for SPATA31A1 Gene

genes like me logo Genes that share phenotypes with SPATA31A1: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SPATA31A1 Gene

Localization for SPATA31A1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SPATA31A1 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for SPATA31A1 Gene COMPARTMENTS Subcellular localization image for SPATA31A1 gene
Compartment Confidence
plasma membrane 2
cytosol 1
extracellular 1
nucleus 1

Gene Ontology (GO) - Cellular Components for SPATA31A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SPATA31A1: view

Pathways & Interactions for SPATA31A1 Gene

SuperPathways for SPATA31A1 Gene

No Data Available

Interacting Proteins for SPATA31A1 Gene

Gene Ontology (GO) - Biological Process for SPATA31A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007283 spermatogenesis IEA --
GO:0030154 cell differentiation IEA --
genes like me logo Genes that share ontologies with SPATA31A1: view

No data available for Pathways by source and SIGNOR curated interactions for SPATA31A1 Gene

Transcripts for SPATA31A1 Gene

mRNA/cDNA for SPATA31A1 Gene

(4) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SPATA31A1 Gene

SPATA31 subfamily A, member 1:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SPATA31A1 Gene

No ASD Table

Relevant External Links for SPATA31A1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SPATA31A1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SPATA31A1 Gene

mRNA differential expression in normal tissues according to GTEx for SPATA31A1 Gene

This gene is overexpressed in Testis (x51.8).

Protein differential expression in normal tissues from HIPED for SPATA31A1 Gene

This gene is overexpressed in Plasma (39.4) and Lung (22.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SPATA31A1 Gene

Protein tissue co-expression partners for SPATA31A1 Gene

NURSA nuclear receptor signaling pathways regulating expression of SPATA31A1 Gene:


SOURCE GeneReport for Unigene cluster for SPATA31A1 Gene:

genes like me logo Genes that share expression patterns with SPATA31A1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for SPATA31A1 Gene

Orthologs for SPATA31A1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for SPATA31A1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC749578 34
  • 98.39 (n)
-- 35
  • 96 (a)
-- 35
  • 96 (a)
(Bos Taurus)
Mammalia SPATA31A3 34
  • 66.01 (n)
-- 35
  • 43 (a)
(Canis familiaris)
Mammalia SPATA31A3 34
  • 65.64 (n)
-- 35
  • 44 (a)
(Rattus norvegicus)
Mammalia Spata31a5 34
  • 59.46 (n)
(Mus musculus)
Mammalia Spata31 34 35
  • 58.94 (n)
Species where no ortholog for SPATA31A1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SPATA31A1 Gene

Gene Tree for SPATA31A1 (if available)
Gene Tree for SPATA31A1 (if available)

Paralogs for SPATA31A1 Gene

(9) SIMAP similar genes for SPATA31A1 Gene using alignment to 1 proteins: Pseudogenes for SPATA31A1 Gene

genes like me logo Genes that share paralogs with SPATA31A1: view

Variants for SPATA31A1 Gene

Sequence variations from dbSNP and Humsavar for SPATA31A1 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs10125162 -- 39,358,957(+) AGAAG(C/T)TCTCA reference, missense
rs112235744 -- 39,360,109(+) AAGCC(A/T)GTGTG reference, missense
rs113128650 -- 39,357,919(-) CTGTA(C/T)CCCTG intron-variant
rs11506642 -- 39,360,709(+) TCGAG(C/G)CTCCA reference, missense
rs11521860 -- 39,357,342(-) TGGCT(G/T)CATTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SPATA31A1 Gene

Variant ID Type Subtype PubMed ID
esv24325 CNV gain+loss 19812545
nsv1119198 CNV deletion 24896259
nsv1137631 CNV deletion 24896259
nsv1144270 CNV deletion 24896259
nsv428215 CNV gain+loss 18775914
nsv469632 CNV gain+loss 16826518
nsv469801 CNV gain 16826518
nsv614284 CNV loss 21841781
nsv820048 CNV loss 19587683
nsv8450 CNV gain+loss 18304495
nsv972319 CNV duplication 23825009
nsv982274 CNV duplication 23825009

Variation tolerance for SPATA31A1 Gene

Gene Damage Index Score: 0.44; 9.65% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SPATA31A1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SPATA31A1 Gene

Disorders for SPATA31A1 Gene

Relevant External Links for SPATA31A1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SPATA31A1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SPATA31A1 Gene

Publications for SPATA31A1 Gene

  1. The testis-specific VAD1.3/AEP1 interacts with I^-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence. (PMID: 20850414) Zuo Y. … Lee K.F. (Biochem. Biophys. Res. Commun. 2010) 2 3 64
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for SPATA31A1 Gene

Sources for SPATA31A1 Gene

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