Free for academic non-profit institutions. Other users need a Commercial license

Aliases for SPATA3 Gene

Aliases for SPATA3 Gene

  • Spermatogenesis Associated 3 2 3 5
  • Testis And Spermatogenesis Cell-Related Protein 1 3 4
  • Testis And Spermatogenesis Cell Apoptosis Related Gene 1 3
  • Testis Spermatocyte Apoptosis-Related Protein 1 3
  • Spermatogenesis-Associated Protein 3 3
  • TSARG1 3

External Ids for SPATA3 Gene

Previous GeneCards Identifiers for SPATA3 Gene

  • GC00U991161
  • GC02P232063
  • GC02P231686
  • GC02P231569
  • GC02P231860
  • GC02P223702

Summaries for SPATA3 Gene

GeneCards Summary for SPATA3 Gene

SPATA3 (Spermatogenesis Associated 3) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPATA3 Gene

Genomics for SPATA3 Gene

Regulatory Elements for SPATA3 Gene

Enhancers for SPATA3 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around SPATA3 on UCSC Golden Path with GeneCards custom track

Genomic Location for SPATA3 Gene

Chromosome:
2
Start:
230,996,121 bp from pter
End:
231,025,056 bp from pter
Size:
28,936 bases
Orientation:
Plus strand

Genomic View for SPATA3 Gene

Genes around SPATA3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SPATA3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SPATA3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPATA3 Gene

Proteins for SPATA3 Gene

  • Protein details for SPATA3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NHX4-SPTA3_HUMAN
    Recommended name:
    Spermatogenesis-associated protein 3
    Protein Accession:
    Q8NHX4
    Secondary Accessions:
    • Q86WX5
    • Q8N9Y6

    Protein attributes for SPATA3 Gene

    Size:
    192 amino acids
    Molecular mass:
    D Da
    Quaternary structure:
    No Data Available

neXtProt entry for SPATA3 Gene

Post-translational modifications for SPATA3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for SPATA3 Gene

Domains & Families for SPATA3 Gene

Protein Domains for SPATA3 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for SPATA3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SPATA3: view

No data available for Gene Families and UniProtKB/Swiss-Prot for SPATA3 Gene

Function for SPATA3 Gene

Gene Ontology (GO) - Molecular Function for SPATA3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with SPATA3: view
genes like me logo Genes that share phenotypes with SPATA3: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SPATA3 Gene

Localization for SPATA3 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SPATA3 Gene COMPARTMENTS Subcellular localization image for SPATA3 gene
Compartment Confidence
nucleus 3
cytosol 1
extracellular 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for SPATA3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with SPATA3: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for SPATA3 Gene

Pathways & Interactions for SPATA3 Gene

SuperPathways for SPATA3 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SPATA3 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SPATA3 Gene

Drugs & Compounds for SPATA3 Gene

No Compound Related Data Available

Transcripts for SPATA3 Gene

Unigene Clusters for SPATA3 Gene

Spermatogenesis associated 3:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SPATA3 Gene

No ASD Table

Relevant External Links for SPATA3 Gene

GeneLoc Exon Structure for
SPATA3
ECgene alternative splicing isoforms for
SPATA3

Expression for SPATA3 Gene

mRNA expression in normal human tissues for SPATA3 Gene

mRNA differential expression in normal tissues according to GTEx for SPATA3 Gene

This gene is overexpressed in Testis (x51.6).

NURSA nuclear receptor signaling pathways regulating expression of SPATA3 Gene:

SPATA3

SOURCE GeneReport for Unigene cluster for SPATA3 Gene:

Hs.745178
genes like me logo Genes that share expression patterns with SPATA3: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for SPATA3 Gene

Orthologs for SPATA3 Gene

This gene was present in the common ancestor of mammals.

Orthologs for SPATA3 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia SPATA3 34
  • 78.77 (n)
  • 70.37 (a)
SPATA3 35
  • 53 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SPATA3 34
  • 72.28 (n)
  • 59.47 (a)
SPATA3 35
  • 59 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Spata3 34
  • 66.14 (n)
  • 57.14 (a)
Spata3 16
Spata3 35
  • 53 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia SPATA3 34
  • 98.09 (n)
  • 95.83 (a)
SPATA3 35
  • 96 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Spata3 34
  • 70.43 (n)
  • 60.75 (a)
Species where no ortholog for SPATA3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SPATA3 Gene

ENSEMBL:
Gene Tree for SPATA3 (if available)
TreeFam:
Gene Tree for SPATA3 (if available)

Paralogs for SPATA3 Gene

No data available for Paralogs for SPATA3 Gene

Variants for SPATA3 Gene

Sequence variations from dbSNP and Humsavar for SPATA3 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs2175148 -- 230,999,212(+) AAATG(C/T)ATTGC intron-variant
rs2175149 -- 231,012,492(-) AGGGT(A/G)TAATC intron-variant
rs4429463 -- 231,018,632(+) CCCCA(C/G)AATCA intron-variant
rs2271370 -- 231,003,057(-) AGGGT(C/T)CATGA intron-variant
rs2271371 -- 231,002,943(-) ATGCC(A/G)GCTGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SPATA3 Gene

Variant ID Type Subtype PubMed ID
esv2721608 CNV deletion 23290073
esv3387907 CNV duplication 20981092
nsv954230 CNV deletion 24416366

Variation tolerance for SPATA3 Gene

Gene Damage Index Score: 9.49; 88.75% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SPATA3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SPATA3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SPATA3 Gene

Disorders for SPATA3 Gene

Relevant External Links for SPATA3

Genetic Association Database (GAD)
SPATA3
Human Genome Epidemiology (HuGE) Navigator
SPATA3
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SPATA3

No disorders were found for SPATA3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SPATA3 Gene

Publications for SPATA3 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 65
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 65
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 65
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 65
  5. Molecular cloning for testis spermatogenesis cell apoptosis related gene TSARG1 and Mtsarg1 and expression analysis for Mtsarg1 gene. (PMID: 12812072) Fu J.J. … Liu S.F. (Yi Chuan Xue Bao 2003) 3 65

Products for SPATA3 Gene

Sources for SPATA3 Gene

Content
Loading form....