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Aliases for SPATA25 Gene

Aliases for SPATA25 Gene

  • Spermatogenesis Associated 25 2 3
  • Testis-Specific Gene 23 Protein 3 4
  • C20orf165 3 4
  • TSG23 3 4
  • Spermatogenesis-Associated Protein 25 3
  • Chromosome 20 Open Reading Frame 165 2
  • DJ337O18.8 3

External Ids for SPATA25 Gene

Previous HGNC Symbols for SPATA25 Gene

  • C20orf165

Previous GeneCards Identifiers for SPATA25 Gene

  • GC20M044516

Summaries for SPATA25 Gene

GeneCards Summary for SPATA25 Gene

SPATA25 (Spermatogenesis Associated 25) is a Protein Coding gene.

UniProtKB/Swiss-Prot for SPATA25 Gene

  • May play a role in spermatogenesis.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPATA25 Gene

Genomics for SPATA25 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SPATA25 Gene

45,886,486 bp from pter
45,888,575 bp from pter
2,090 bases
Minus strand

Genomic View for SPATA25 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SPATA25 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPATA25 Gene

No data available for Regulatory Elements for SPATA25 Gene

Proteins for SPATA25 Gene

  • Protein details for SPATA25 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Spermatogenesis-associated protein 25
    Protein Accession:
    Secondary Accessions:

    Protein attributes for SPATA25 Gene

    227 amino acids
    Molecular mass:
    23834 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SPATA25 Gene

Proteomics data for SPATA25 Gene at MOPED

Post-translational modifications for SPATA25 Gene

No Post-translational modifications

Other Protein References for SPATA25 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SPATA25 Gene

Domains for SPATA25 Gene

Protein Domains for SPATA25 Gene


Graphical View of Domain Structure for InterPro Entry



  • Q9BR10
  • Belongs to the SPATA25 family.
genes like me logo Genes that share domains with SPATA25: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for SPATA25 Gene

Function for SPATA25 Gene

Molecular function for SPATA25 Gene

UniProtKB/Swiss-Prot Function: May play a role in spermatogenesis.

Gene Ontology (GO) - Molecular Function for SPATA25 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with SPATA25: view

Phenotypes for SPATA25 Gene

GenomeRNAi human phenotypes for SPATA25:
genes like me logo Genes that share phenotypes with SPATA25: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SPATA25

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SPATA25 Gene

Localization for SPATA25 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SPATA25 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SPATA25 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SPATA25: view

No data available for Subcellular locations from COMPARTMENTS for SPATA25 Gene

Pathways for SPATA25 Gene

SuperPathways for SPATA25 Gene

No Data Available

Interacting Proteins for SPATA25 Gene

Gene Ontology (GO) - Biological Process for SPATA25 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007283 spermatogenesis IEP 19240080
GO:0030154 cell differentiation IEA --
genes like me logo Genes that share ontologies with SPATA25: view

No data available for Pathways by source for SPATA25 Gene

Transcripts for SPATA25 Gene

mRNA/cDNA for SPATA25 Gene

(10) Selected AceView cDNA sequences:
(2) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SPATA25 Gene

Spermatogenesis associated 25:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SPATA25

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for SPATA25
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SPATA25 Gene

No ASD Table

Relevant External Links for SPATA25 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SPATA25 Gene

mRNA expression in normal human tissues for SPATA25 Gene

mRNA differential expression in normal tissues according to GTEx for SPATA25 Gene

This gene is overexpressed in Testis (7.8).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for SPATA25 Gene

SOURCE GeneReport for Unigene cluster for SPATA25 Gene Hs.128235

mRNA Expression by UniProt/SwissProt for SPATA25 Gene

Tissue specificity: Expressed predominantly in testis (at protein level). Expression is lower in patients with obstructive azoospermia than in fertile controls and is not detected in patients with non-obstructive azoospermia.
genes like me logo Genes that share expressions with SPATA25: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for SPATA25 Gene

Orthologs for SPATA25 Gene

This gene was present in the common ancestor of mammals.

Orthologs for SPATA25 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SPATA25 35
  • 98.38 (n)
  • 97.36 (a)
SPATA25 36
  • 97 (a)
(Bos Taurus)
Mammalia SPATA25 35
  • 84.25 (n)
  • 75.23 (a)
SPATA25 36
  • 75 (a)
(Canis familiaris)
Mammalia SPATA25 35
  • 88.84 (n)
  • 81.5 (a)
SPATA25 36
  • 82 (a)
(Mus musculus)
Mammalia Spata25 35
  • 84.75 (n)
  • 80.72 (a)
Spata25 16
Spata25 36
  • 80 (a)
(Monodelphis domestica)
Mammalia SPATA25 36
  • 70 (a)
(Rattus norvegicus)
Mammalia Spata25 35
  • 86.1 (n)
  • 82.51 (a)
Species with no ortholog for SPATA25:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SPATA25 Gene

Gene Tree for SPATA25 (if available)
Gene Tree for SPATA25 (if available)

Paralogs for SPATA25 Gene

No data available for Paralogs for SPATA25 Gene

Variants for SPATA25 Gene

Sequence variations from dbSNP and Humsavar for SPATA25 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type MAF
rs3827040 - 45,886,920(+) CATGC(A/G)GGAAT reference, missense
rs6032575 -- 45,886,752(+) TATCA(A/G)GCTGG reference, missense
rs6032576 -- 45,887,456(+) AGAAC(C/T)GCCAC intron-variant
rs6094224 -- 45,886,420(+) CCAGC(C/T)CTATC downstream-variant-500B
rs6104387 -- 45,886,137(+) CTTGA(C/G)CCCAG downstream-variant-500B

Relevant External Links for SPATA25 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SPATA25 Gene

Disorders for SPATA25 Gene

No disorders were found for SPATA25 Gene.

No data available for UniProtKB/Swiss-Prot for SPATA25 Gene

Publications for SPATA25 Gene

  1. Developmental expression pattern of a novel gene, TSG23/Tsg23, suggests a role in spermatogenesis. (PMID: 19240080) Zhou Y. … Gui Y. (Mol. Hum. Reprod. 2009) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for SPATA25 Gene

Sources for SPATA25 Gene

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