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SPATA22 Gene

protein-coding   GIFtS: 48
GCID: GC17M003343

Spermatogenesis Associated 22

  Search for SPATA22
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Spermatogenesis Associated 221 2
Testis Development Protein NYD-SP202 3
NYD-SP202
NYDSP202
Spermatogenesis-Associated Protein 222
Testes Development-Related NYD-SP202

External Ids:    HGNC: 307051   Entrez Gene: 846902   Ensembl: ENSG000001412557   UniProtKB: Q8NHS93   

Export aliases for SPATA22 gene to outside databases

Previous GC identifers: GC17M003291 GC17M003235


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SPATA22 Gene:
SPATA22 (spermatogenesis associated 22) is a protein-coding gene.

UniProtKB/Swiss-Prot: SPT22_HUMAN, Q8NHS9
Function: Meiosis-specific protein required for homologous recombination in meiosis I (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NT_010718.17  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SPATA22 gene promoter:
         Elk-1   AML1a   IRF-1   Cdc5   YY1   Evi-1   POU2F1   FOXC1   POU2F1a   LyF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSPATA22 promoter sequence
   Search Chromatin IP Primers for SPATA22

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SPATA22


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.3   Ensembl cytogenetic band:  17p13.2   HGNC cytogenetic band: 17p13.3

SPATA22 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SPATA22 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M003343:  view genomic region     (about GC identifiers)

Start:
3,343,305 bp from pter      End:
3,417,146 bp from pter
Size:
73,842 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SPT22_HUMAN, Q8NHS9 (See protein sequence)
Recommended Name: Spermatogenesis-associated protein 22  
Size: 363 amino acids; 41318 Da
Subunit: Component of a multiprotein complex with MEIOB and SPATA22 (By similarity)
Secondary accessions: B4DXB1 D3DTI9 J3KN63 Q969H3 Q96JT4
Alternative splicing: 3 isoforms:  Q8NHS9-1   Q8NHS9-2   Q8NHS9-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SPATA22: NX_Q8NHS9

Explore proteomics data for SPATA22 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SPATA22 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (6 alternative transcripts): 
    NP_001164166.1  NP_001164167.1  NP_001164168.1  NP_001164169.1  NP_001164170.1  NP_115987.2  

    ENSEMBL proteins: 
     ENSP00000380354   ENSP00000460187   ENSP00000347541   ENSP00000459329   ENSP00000459580  
     ENSP00000441920   ENSP00000268981   ENSP00000459552   ENSP00000461462   ENSP00000461722  
     ENSP00000461180   ENSP00000458923   ENSP00000460692   ENSP00000459147  

    SPATA22 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for SPATA22

     
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    Cloud-Clone Corp. CLIAs for SPATA22
    Search eBioscience for ELISAs for SPATA22 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    ProtoNet protein and cluster: Q8NHS9


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SPT22_HUMAN, Q8NHS9
    Function: Meiosis-specific protein required for homologous recombination in meiosis I (By similarity)

    Phenotypes:
         1 GenomeRNAi human phenotype for SPATA22:

     Decreased melanin production 

         4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Spata22):
     cellular  endocrine/exocrine gland  homeostasis/metabolism  reproductive system 

    Find genes that share phenotypes with SPATA22           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SPATA22
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SPATA22

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SPATA22
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SPATA22

    miRNA
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    Block miRNA regulation of human, mouse, rat SPATA22 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate SPATA22
    SwitchGear 3'UTR luciferase reporter plasmidSPATA22 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Predesigned siRNA for gene silencing in human, mouse, rat SPATA22

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    DNA2.0 Custom Protein Engineering Service for SPATA22

    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 6): SPATA22 (NM_032598)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SPATA22
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPATA22

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPATA22


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SPT22_HUMAN, Q8NHS9: Chromosome (By similarity). Note=Localizes on meiotic chromosome axes. Accumulates on
    resected DNA. Localization is dependent on MEIOB (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion3
    nucleus2
    cytosol1
    extracellular1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005694chromosome IEA--

    Find genes that share ontologies with SPATA22           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SPATA22
    Interactions:

        Search GeneGlobe Interaction Network for SPATA22

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for SPATA22 (Q8NHS92, 3 ENSP000002689814) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TRAPPC2LQ9UL332, 3, ENSP000003010214MINT-8201631 I2D: score=1 STRING: ENSP00000301021
    --Q9CQP22MINT-8201620
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000711meiotic DNA repair synthesis IEA--
    GO:0007129synapsis IEA--
    GO:0007276gamete generation IEA--
    GO:0009566fertilization IEA--
    GO:0051445regulation of meiotic cell cycle IEA--

    Find genes that share ontologies with SPATA22           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SPATA22 (SPT22)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SPATA22 gene (6 alternative transcripts): 
    NM_001170695.1  NM_001170696.1  NM_001170697.1  NM_001170698.1  NM_001170699.1  NM_032598.4  

    Unigene Cluster for SPATA22:

    Spermatogenesis associated 22
    Hs.351068  [show with all ESTs]
    Unigene Representative Sequence: AK295299
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000397168(uc002fvm.3 uc010vrf.2) ENST00000572969(uc002fvo.3)
    ENST00000355380 ENST00000575375 ENST00000573128(uc002fvn.3 uc002fvp.3 uc010ckf.3)
    ENST00000541913 ENST00000268981 ENST00000571553 ENST00000574051 ENST00000574797
    ENST00000572582 ENST00000571607 ENST00000574457 ENST00000570318
    miRNA
    Products:
         
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    Search for qRT-PCR Assays for microRNAs that regulate SPATA22
    SwitchGear 3'UTR luciferase reporter plasmidSPATA22 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SPATA22
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    OriGene ORF clones in mouse, rat for SPATA22
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 6): SPATA22 (NM_032598)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPATA22
    Primer
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    OriGene qPCR primer pairs and template standards for SPATA22
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SPATA22
      QuantiTect SYBR Green Assays in human, mouse, rat SPATA22
      QuantiFast Probe-based Assays in human, mouse, rat SPATA22

    Additional mRNA sequence: 

    AF367472.1 AK295299.1 AK301892.1 AY032684.1 AY035867.1 AY035868.1 BC029483.1 

    8 DOTS entries:

    DT.95375334  DT.95375336  DT.95375335  DT.95375332  DT.100024224  DT.120974241  DT.91756453  DT.95375333 

    Selected AceView cDNA sequences (see all 76):

    AI200932 BX116166 AI651860 BF062332 AI638483 BP371122 BI829128 CD557477 
    BF057853 BQ432609 AA977048 BI463870 AY032684 AA470124 BC029483 AW515779 
    BG722715 BI461728 BU570127 BI826018 AK057485 BM560312 BU567954 AA853961 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SPATA22 (see all 7)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d · 2e ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b
    SP1:                          -     -                                                                     
    SP2:                                                                                                      
    SP3:                                -                                                                     
    SP4:                          -     -           -     -     -                                             
    SP5:        -     -     -     -     -                                                                     


    ECgene alternative splicing isoforms for SPATA22

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SPATA22 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CACAGAAAAC
    SPATA22 Expression
    About this image


    SPATA22 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Gonad
             Secondary Spermatocyte Seminiferous Tubules
     
     Testis (Reproductive System)
             Secondary Spermatocyte Seminiferous Tubules
     
     Ovary (Reproductive System)
             XX Germ Cells Ovigerous Cord
    SPATA22 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SPATA22 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.351068

    UniProtKB/Swiss-Prot: SPT22_HUMAN, Q8NHS9
    Tissue specificity: Highly expressed in adult testis

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPATA22

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for SPATA22 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Spata221 , 5 spermatogenesis associated 221, 5 82.35(n)1
    72.83(a)1
      11 (45.29 cM)5
    3807091  NM_001045531.11  NP_001038996.11 
     733297415 
    chicken
    (Gallus gallus)
    Aves SPATA221 spermatogenesis associated 22 64.89(n)
    54.92(a)
      771958  XM_001235167.3  XP_001235168.2 
    lizard
    (Anolis carolinensis)
    Reptilia SPATA226
    spermatogenesis associated 22
    44(a)
    1 ↔ 1
    GL343393.1(207791-215311)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia spata221 spermatogenesis associated 22 55.32(n)
    45.9(a)
      100485180  XM_002938241.2  XP_002938287.2 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003307301 spermatogenesis-associated protein 22-like 57.28(n)
    49.3(a)
      100330730  XM_005165581.1  XP_005165638.1 


    ENSEMBL Gene Tree for SPATA22 (if available)
    TreeFam Gene Tree for SPATA22 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SPATA22 (see all 745)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1456712041,2
    C--3342845(+) CTACCA/GCTCCT 6 -- int10--------
    rs758375341,2
    C,F--3342939(+) GCACCC/TCTAAT 6 -- int11Minor allele frequency- T:0.03WA 118
    rs1477425621,2
    --3343005(+) AAGCAC/GATTTT 6 -- int10--------
    rs1813535681,2
    --3343066(+) AACAAG/TGCTTA 6 -- int10--------
    rs1863679161,2
    --3343110(+) TTCCTA/GATAGT 6 -- int10--------
    rs1905424991,2
    --3343147(+) AAGCCC/TAATGC 6 -- int10--------
    rs1827259091,2
    --3343217(+) CTGTTA/GCAGTG 6 -- int10--------
    rs1879374111,2
    --3343223(+) CAGTGA/GGCATT 6 -- int10--------
    rs1501869481,2
    C--3343269(+) ACCATC/TTTAAT 6 -- int10--------
    rs22577321,2
    C,F,H--3343406(+) AAACTG/ACTATA 6 -- ut31 ese323Minor allele frequency- A:0.03NS EA NA EU 2811

    HapMap Linkage Disequilibrium report for SPATA22 (3343305 - 3417146 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for SPATA22:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1173810CNV Deletion17803354
    esv2660206CNV Deletion23128226
    nsv907553CNV Loss21882294
    nsv833341CNV Loss17160897
    nsv528368CNV Gain19592680
    nsv521277CNV Gain19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SPATA22
    DNA2.0 Custom Variant and Variant Library Synthesis for SPATA22

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with SPATA22           About GenesLikeMe

    Genetic Association Database (GAD): SPATA22
    Human Genome Epidemiology (HuGE) Navigator: SPATA22 (1 document)

    Export disorders for SPATA22 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SPATA22 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with SPATA22)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent. (PubMed id 20378615)1, 4 Aston K.I....Carrell D.T. (Hum. Reprod. 2010)
    2. Novel development-related alternative splices in human testis identified by cDNA microarrays. (PubMed id 15713825)1, 2 Huang X....Sha J.H. (J. Androl. 2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    6. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (Nat. Methods 2013)
    7. Expression analysis of MND1/GAJ, SPATA22, GAPDHS and ACR genes in testicular biopsies from non-obstructive azoospermia (NOA) patients. (PubMed id 23675907)1 Dorosh A....Peknicova J. (amp 2013)
    8. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (Sci Signal 2012)
    9. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)2 Zody M.C.... Nusbaum C. (Nature 2006)
    10. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 84690 HGNC: 30705 AceView: NYD-SP20 Ensembl:ENSG00000141255 euGenes: HUgn84690
    ECgene: SPATA22 H-InvDB: SPATA22

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for SPATA22 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SPATA22 gene:
    Search GeneIP for patents involving SPATA22

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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