Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SPATA22 Gene

protein-coding   GIFtS: 48
GCID: GC17M003343

Spermatogenesis Associated 22

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Spermatogenesis Associated 221 2
Testis Development Protein NYD-SP202 3
NYD-SP202
NYDSP202
Spermatogenesis-Associated Protein 222
Testes Development-Related NYD-SP202

External Ids:    HGNC: 307051   Entrez Gene: 846902   Ensembl: ENSG000001412557   UniProtKB: Q8NHS93   

Export aliases for SPATA22 gene to outside databases

Previous GC identifers: GC17M003291 GC17M003235


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for SPATA22 Gene: 
SPATA22 (spermatogenesis associated 22) is a protein-coding gene. Diseases associated with SPATA22 include azoospermia.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NT_010718.16  NC_018928.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SPATA22 gene promoter:
         Elk-1   AML1a   IRF-1   Cdc5   YY1   Evi-1   POU2F1   FOXC1   POU2F1a   LyF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSPATA22 promoter sequence
   Search SABiosciences Chromatin IP Primers for SPATA22

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SPATA22


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.3   Ensembl cytogenetic band:  17p13.2   HGNC cytogenetic band: 17p13.3

SPATA22 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SPATA22 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M003343:  view genomic region     (about GC identifiers)

Start:
3,343,305 bp from pter      End:
3,417,146 bp from pter
Size:
73,842 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SPT22_HUMAN, Q8NHS9 (See protein sequence)
Recommended Name: Spermatogenesis-associated protein 22  
Size: 363 amino acids; 41318 Da
Secondary accessions: B4DXB1 D3DTI9 J3KN63 Q969H3 Q96JT4
Alternative splicing: 3 isoforms:  Q8NHS9-1   Q8NHS9-2   Q8NHS9-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SPATA22: NX_Q8NHS9

Explore proteomics data for SPATA22 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8NHS9

  • SPATA22 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SPATA22 Protein Expression
    REFSEQ proteins (6 alternative transcripts): 
    NP_001164166.1  NP_001164167.1  NP_001164168.1  NP_001164169.1  NP_001164170.1  NP_115987.2  

    ENSEMBL proteins: 
     ENSP00000380354   ENSP00000460187   ENSP00000347541   ENSP00000459329   ENSP00000459580  
     ENSP00000441920   ENSP00000268981   ENSP00000459552   ENSP00000461462   ENSP00000461722  
     ENSP00000461180   ENSP00000458923   ENSP00000460692   ENSP00000459147  

    Human Recombinant Protein Products for SPATA22: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for SPATA22
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for SPATA22
    GenScript Custom Purified and Recombinant Proteins Services for SPATA22
    Novus Biologicals SPATA22 Protein
    Novus Biologicals SPATA22 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SPATA22 


    SPATA22 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for SPATA22
    GenScript Custom Superior Antibodies Services for SPATA22
    Novus Biologicals SPATA22 Antibody
    Abcam antibodies for SPATA22
    Cloud-Clone Corp. Antibodies for SPATA22 
    ThermoFisher Antibody for SPATA22
    LSBio Antibodies in human, mouse, rat for SPATA22 

    Assay Products for SPATA22: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for SPATA22
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SPATA22
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SPATA22 
    Cloud-Clone Corp. CLIAs for SPATA22


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ProtoNet protein and cluster: Q8NHS9


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Phenotypes:
         1 GenomeRNAi human phenotype for SPATA22:
     Decreased melanin production 

         4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Spata22):
     cellular  endocrine/exocrine gland  homeostasis/metabolism  reproductive system 

    SPATA22 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SPATA22 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SPATA22

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SPATA22 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SPATA22 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SPATA22
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate SPATA22
    SwitchGear 3'UTR luciferase reporter plasmidSPATA22 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SPATA22
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SPATA22

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SPATA22
    Sirion Biotech Customized adenovirus for overexpression of SPATA22

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for SPATA22 (see all 27)
    OriGene ORF clones in mouse, rat for SPATA22
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 6): SPATA22 (NM_032598)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SPATA22
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPATA22
    Sirion Biotech Customized lentivirus for stable overexpression of SPATA22 
                         Customized lentivirus expression plasmids for stable overexpression of SPATA22 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SPATA22
    Search LifeMap BioReagents cell lines for SPATA22
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPATA22


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SPATA22

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for SPATA22 (Q8NHS92, 3 ENSP000002689814) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TRAPPC2LQ9UL332, 3, ENSP000003010214MINT-8201631 I2D: score=1 STRING: ENSP00000301021
    --Q9CQP22MINT-8201620
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000711meiotic DNA repair synthesis IEA--
    GO:0007129synapsis IEA--
    GO:0007276gamete generation IEA--
    GO:0009566fertilization IEA--
    GO:0051445regulation of meiotic cell cycle IEA--

    SPATA22 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SPATA22 (SPT22)

    Search CenterWatch for drugs/clinical trials and news about SPATA22 / SPT22

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SPATA22 gene (6 alternative transcripts): 
    NM_001170695.1  NM_001170696.1  NM_001170697.1  NM_001170698.1  NM_001170699.1  NM_032598.4  

    Unigene Cluster for SPATA22:

    Spermatogenesis associated 22
    Hs.351068  [show with all ESTs]
    Unigene Representative Sequence: AK295299
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000397168(uc002fvm.3 uc010vrf.2) ENST00000572969(uc002fvo.3)
    ENST00000355380 ENST00000575375 ENST00000573128(uc002fvn.3 uc002fvp.3 uc010ckf.3)
    ENST00000541913 ENST00000268981 ENST00000571553 ENST00000574051 ENST00000574797
    ENST00000572582 ENST00000571607 ENST00000574457 ENST00000570318
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SPATA22
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate SPATA22
    SwitchGear 3'UTR luciferase reporter plasmidSPATA22 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SPATA22
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SPATA22
    Clone
    Products:
         
    OriGene clones in human, mouse for SPATA22 (see all 27)
    OriGene ORF clones in mouse, rat for SPATA22
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 6): SPATA22 (NM_032598)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SPATA22
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPATA22
    Sirion Biotech Customized lentivirus for stable overexpression of SPATA22 
                         Customized lentivirus expression plasmids for stable overexpression of SPATA22 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for SPATA22
    OriGene qSTAR qPCR primer pairs in human, mouse for SPATA22
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SPATA22
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SPATA22
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SPATA22

    Additional mRNA sequence: 

    AF367472.1 AK295299.1 AK301892.1 AY032684.1 AY035867.1 AY035868.1 BC029483.1 

    8 DOTS entries:

    DT.95375334  DT.95375336  DT.95375335  DT.95375332  DT.100024224  DT.120974241  DT.91756453  DT.95375333 

    24/76 AceView cDNA sequences (see all 76):

    BP371122 AI651860 AI200932 AI638483 CD557477 BF062332 BX116166 BF057853 
    BI829128 BU854384 BU570617 BU570151 BU568672 AA977048 AW515779 BG722715 
    BI826018 BG720739 BU568197 BU561423 BF438413 BU568424 BP370941 BM560312 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for SPATA22 (see all 7)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d · 2e ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b
    SP1:                          -     -                                                                     
    SP2:                                                                                                      
    SP3:                                -                                                                     
    SP4:                          -     -           -     -     -                                             
    SP5:        -     -     -     -     -                                                                     


    ECgene alternative splicing isoforms for SPATA22

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SPATA22 expression in normal human tissues (normalized intensities)      SPATA22 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CACAGAAAAC
    SPATA22 Expression
    About this image


    SPATA22 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Testis (Reproductive System)
             sperm   
     
     Ovary (Reproductive System)
             XX Germ Cells Ovigerous Cord
     
     Gonad
             XX Germ Cells Ovigerous Cord

    See SPATA22 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SPATA22

    SOURCE GeneReport for Unigene cluster: Hs.351068

    UniProtKB/Swiss-Prot: SPT22_HUMAN, Q8NHS9
    Tissue specificity: Highly expressed in adult testis

        SABiosciences Custom PCR Arrays for SPATA22
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for SPATA22
    OriGene qSTAR qPCR primer pairs in human, mouse for SPATA22
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SPATA22
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SPATA22
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SPATA22
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPATA22

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for SPATA22 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Spata221 , 5 spermatogenesis associated 221, 5 82.35(n)1
    72.83(a)1
      11 (45.29 cM)5
    3807091  NM_001045531.11  NP_001038996.11 
     733297415 
    chicken
    (Gallus gallus)
    Aves SPATA221 spermatogenesis associated 22 62.16(n)
    52.01(a)
      771958  XM_001235167.2  XP_001235168.1 
    lizard
    (Anolis carolinensis)
    Reptilia SPATA226
    spermatogenesis associated 22
    41(a)
    1 ↔ 1
    GL343393.1(207791-215311)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003307301 spermatogenesis-associated protein 22-like 50.49(n)
    41.04(a)
      100330730  XM_002666586.2  XP_002666632.1 


    ENSEMBL Gene Tree for SPATA22 (if available)
    TreeFam Gene Tree for SPATA22 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/745 SNPs in SPATA22 are shown (see all 745)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1456712041,2
    C--3342845(+) CTACCA/GCTCCT 6 -- int10--------
    rs758375341,2
    C,F--3342939(+) GCACCC/TCTAAT 6 -- int11Minor allele frequency- T:0.03WA 118
    rs1477425621,2
    --3343005(+) AAGCAC/GATTTT 6 -- int10--------
    rs1813535681,2
    --3343066(+) AACAAG/TGCTTA 6 -- int10--------
    rs1863679161,2
    --3343110(+) TTCCTA/GATAGT 6 -- int10--------
    rs1905424991,2
    --3343147(+) AAGCCC/TAATGC 6 -- int10--------
    rs1827259091,2
    --3343217(+) CTGTTA/GCAGTG 6 -- int10--------
    rs1879374111,2
    --3343223(+) CAGTGA/GGCATT 6 -- int10--------
    rs1501869481,2
    C--3343269(+) ACCATC/TTTAAT 6 -- int10--------
    rs22577321,2
    C,F,H--3343406(+) AAACTG/ACTATA 6 -- ut31 ese323Minor allele frequency- A:0.03NS EA NA EU 2811

    HapMap Linkage Disequilibrium report for SPATA22 (3343305 - 3417146 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for SPATA22:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv1173810CNV Deletion17803354
    esv2660206CNV Deletion23128226
    nsv907553CNV Loss21882294
    nsv833341CNV Loss17160897
    nsv528368CNV Gain19592680
    nsv521277CNV Gain19592680

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SPATA22
    DNA2.0 Custom Variant and Variant Library Synthesis for SPATA22

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for SPATA22:    About MalaCards
    azoospermia    


    SPATA22 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SPATA22
    Human Genome Epidemiology (HuGE) Navigator: SPATA22 (1 document)

    Export disorders for SPATA22 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SPATA22 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with SPATA22)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Evaluation of 172 candidate polymorphisms for associa tion with oligozoospermia or azoospermia in a large cohort of men of European d escent. (PubMed id 20378615)1, 4 Aston K.I....Carrell D.T. (2010)
    2. Novel development-related alternative splices in human testis identified by cDNA microarrays. (PubMed id 15713825)1, 2 Huang X....Sha J.H. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    6. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (2013)
    7. Expression analysis of MND1/GAJ, SPATA22, GAPDHS and A CR genes in testicular biopsies from non-obstructive azoospermia (NOA) patients. (PubMed id 23675907)1 Dorosh A....Peknicova J. (2013)
    8. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
    9. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)2 Zody M.C.... Nusbaum C. (2006)
    10. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 84690 HGNC: 30705 AceView: NYD-SP20 Ensembl:ENSG00000141255 euGenes: HUgn84690
    ECgene: SPATA22 H-InvDB: SPATA22

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SPATA22 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SPATA22 gene:
    Search GeneIP for patents involving SPATA22

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for SPATA22  
     OriGene qPCR primer pairs and template standards for SPATA22   OriGene Protein Over-expression Lysate for SPATA22  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for SPATA22  
     OriGene qSTAR qPCR primer pairs in human, mouse for SPATA22   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for SPATA22   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SPATA22   OriGene Custom Protein Services for SPATA22  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SPATA22
     QIAGEN SeqTarget long-range PCR primers for resequencing SPATA22
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SPATA22
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SPATA22
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SPATA22
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SPATA22
     GenScript Custom Purified and Recombinant Proteins Services for SPATA22 GenScript cDNA clones with any tag delivered in your preferred vector for SPATA22
     GenScript Custom Assay Services for SPATA22 GenScript Custom Superior Antibodies Services for SPATA22
     GenScript Custom overexpressing Cell Line Services for SPATA22 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in SPATA22 promoter
     Search Chromatin IP Primers for SPATA22
     RT2 qPCR Primer Assay in human, mouse, rat SPATA22
     Search GNC Networks for SPATA22
     SABiosciences Custom PCR Arrays for SPATA22
     Search Tocris compounds for SPATA22 (SPT22)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     SPATA22 antibodies
     SPATA22 proteins
     SPATA22 lysates
     Antibodies for SPATA22
     See all of Abcam's Antibodies, Kits and Proteins for SPATA22
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for SPATA22
     Antibodies for SPATA22
     ELISAs for SPATA22
     CLIAs for SPATA22
     Search LifeMap BioReagents cell lines for SPATA22
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPATA22
     SwitchGear 3'UTR luciferase reporter plasmids for SPATA22
     SwitchGear Promoter luciferase reporter plasmids for SPATA22
     ThermoFisher Antibody for SPATA22
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPATA22
     inGenious Targeting Laboratory - Custom generated mouse model solutions for SPATA22
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SPATA22
    Customized:
     lentivirus for stable overexpression of SPATA22
     lentivirus expression plasmids for stable overexpression of SPATA22
     adenovirus for overexpression of SPATA22
     LSBio Antibodies in human, mouse, rat for SPATA22
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      SPATA22 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4