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Aliases for SPATA20 Gene

Aliases for SPATA20 Gene

  • Spermatogenesis Associated 20 2 3
  • SSP411 3 4 6
  • Sperm-Specific Protein 411 3 4
  • Transcript Increased In Spermiogenesis 78 3
  • Spermatogenesis-Associated Protein 20 3
  • Hypothetical Protein FLJ21347 2
  • Sperm Protein SSP411 3
  • Tisp78 3

External Ids for SPATA20 Gene

Previous GeneCards Identifiers for SPATA20 Gene

  • GC17P045980
  • GC17P048624
  • GC17P043992

Summaries for SPATA20 Gene

GeneCards Summary for SPATA20 Gene

SPATA20 (Spermatogenesis Associated 20) is a Protein Coding gene. GO annotations related to this gene include mannose-6-phosphate isomerase activity.

UniProtKB/Swiss-Prot for SPATA20 Gene

  • May play a role in fertility regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPATA20 Gene

Genomics for SPATA20 Gene

Regulatory Elements for SPATA20 Gene

Genomic Location for SPATA20 Gene

Start:
50,543,058 bp from pter
End:
50,555,852 bp from pter
Size:
12,795 bases
Orientation:
Plus strand

Genomic View for SPATA20 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SPATA20 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPATA20 Gene

Proteins for SPATA20 Gene

  • Protein details for SPATA20 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TB22-SPT20_HUMAN
    Recommended name:
    Spermatogenesis-associated protein 20
    Protein Accession:
    Q8TB22
    Secondary Accessions:
    • Q2TA99
    • Q2XUZ6
    • Q6P0P1
    • Q8WVW3
    • Q9H747

    Protein attributes for SPATA20 Gene

    Size:
    786 amino acids
    Molecular mass:
    87899 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SPATA20 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SPATA20 Gene

Proteomics data for SPATA20 Gene at MOPED

Post-translational modifications for SPATA20 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

No data available for DME Specific Peptides for SPATA20 Gene

Domains for SPATA20 Gene

Suggested Antigen Peptide Sequences for SPATA20 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SPATA20: view

No data available for Gene Families and UniProtKB/Swiss-Prot for SPATA20 Gene

Function for SPATA20 Gene

Molecular function for SPATA20 Gene

UniProtKB/Swiss-Prot Function:
May play a role in fertility regulation.

Gene Ontology (GO) - Molecular Function for SPATA20 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003824 catalytic activity IEA --
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with SPATA20: view
genes like me logo Genes that share phenotypes with SPATA20: view

Animal Model Products

CRISPR Products

miRNA for SPATA20 Gene

miRTarBase miRNAs that target SPATA20

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SPATA20

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for SPATA20 Gene

Localization for SPATA20 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SPATA20 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SPATA20 Gene COMPARTMENTS Subcellular localization image for SPATA20 gene
Compartment Confidence
extracellular 3
nucleus 3
cytosol 2
mitochondrion 2

Gene Ontology (GO) - Cellular Components for SPATA20 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with SPATA20: view

Pathways for SPATA20 Gene

SuperPathways for SPATA20 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SPATA20 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007275 multicellular organismal development IEA --
GO:0007283 spermatogenesis IEA --
GO:0008152 metabolic process IEA --
GO:0030154 cell differentiation IEA --
genes like me logo Genes that share ontologies with SPATA20: view

No data available for Pathways by source for SPATA20 Gene

Transcripts for SPATA20 Gene

Unigene Clusters for SPATA20 Gene

Spermatogenesis associated 20:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SPATA20

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SPATA20 Gene

ExUns: 1 ^ 2a · 2b · 2c · 2d · 2e ^ 3a · 3b ^ 4 ^ 5a · 5b · 5c · 5d · 5e ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b · 10c · 10d ^ 11 ^
SP1: - - - - - - -
SP2: - - - - - - -
SP3: - - - - - - - -
SP4: - - - - - - - - -
SP5: - -
SP6: - - - - - - - -
SP7: - - - -
SP8:
SP9: - - - - - - - - -
SP10: - - - - - -
SP11: - -
SP12:
SP13: - - - - - - - -
SP14: - - - - - -
SP15: - - - - - - - -
SP16: -
SP17:
SP18:
SP19:
SP20: - - - - -
SP21: -
SP22:
SP23: -
SP24: - - - - - - - -
SP25:

ExUns: 12 ^ 13a · 13b ^ 14a · 14b · 14c ^ 15 ^ 16a · 16b · 16c · 16d ^ 17a · 17b · 17c ^ 18a · 18b ^ 19 ^ 20 ^ 21 ^ 22 ^ 23a · 23b
SP1: - - -
SP2: - - -
SP3: - - -
SP4: - - -
SP5: - -
SP6: -
SP7:
SP8: -
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16: - - -
SP17:
SP18: - - -
SP19:
SP20:
SP21:
SP22: - -
SP23:
SP24:
SP25: - -

Relevant External Links for SPATA20 Gene

GeneLoc Exon Structure for
SPATA20
ECgene alternative splicing isoforms for
SPATA20

Expression for SPATA20 Gene

mRNA expression in normal human tissues for SPATA20 Gene

Protein differential expression in normal tissues for SPATA20 Gene

This gene is overexpressed in Adrenal (12.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for SPATA20 Gene

SOURCE GeneReport for Unigene cluster for SPATA20 Gene Hs.103147

genes like me logo Genes that share expressions with SPATA20: view

Expression partners for SPATA20 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SPATA20 Gene

Orthologs for SPATA20 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for SPATA20 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia SPATA20 35
  • 90.15 (n)
  • 93.38 (a)
SPATA20 36
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SPATA20 35
  • 89.15 (n)
  • 94.53 (a)
mouse
(Mus musculus)
Mammalia Spata20 35
  • 84.37 (n)
  • 88.41 (a)
Spata20 16
Spata20 36
  • 86 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia SPATA20 35
  • 99.45 (n)
  • 99.36 (a)
SPATA20 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Spata20 35
  • 84.55 (n)
  • 88.28 (a)
oppossum
(Monodelphis domestica)
Mammalia SPATA20 36
  • 66 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 60 (a)
OneToMany
-- 36
  • 60 (a)
OneToMany
-- 36
  • 62 (a)
OneToMany
-- 36
  • 67 (a)
OneToMany
chicken
(Gallus gallus)
Aves SPATA20 35
  • 67.54 (n)
  • 63.32 (a)
SPATA20 36
  • 63 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SPATA20 36
  • 59 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia spata20 35
  • 60.92 (n)
  • 58.03 (a)
zebrafish
(Danio rerio)
Actinopterygii spata20 35
  • 60.93 (n)
  • 60.3 (a)
spata20 36
  • 55 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP008252 35
  • 51.98 (n)
  • 42.61 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG8613 35
  • 51.97 (n)
  • 43.53 (a)
CG8613 36
  • 39 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea B0495.5 35
  • 47.18 (n)
  • 41.55 (a)
B0495.5 36
  • 39 (a)
OneToOne
thale cress
(Arabidopsis thaliana)
eudicotyledons AT4G03200 35
  • 49.33 (n)
  • 46.18 (a)
rice
(Oryza sativa)
Liliopsida Os.23695 35
Species with no ortholog for SPATA20:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SPATA20 Gene

ENSEMBL:
Gene Tree for SPATA20 (if available)
TreeFam:
Gene Tree for SPATA20 (if available)

Paralogs for SPATA20 Gene

Selected SIMAP similar genes for SPATA20 Gene using alignment to 6 proteins:

Pseudogenes.org Pseudogenes for SPATA20 Gene

genes like me logo Genes that share paralogs with SPATA20: view

No data available for Paralogs for SPATA20 Gene

Variants for SPATA20 Gene

Sequence variations from dbSNP and Humsavar for SPATA20 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs182078 -- 50,550,818(+) CTCCT(C/G)CCGGA reference, synonymous-codon
rs198534 -- 50,549,718(+) TCAGT(G/T)ACCCA intron-variant
rs739924 -- 50,554,246(+) TGTGC(C/T)GTAGA intron-variant
rs873839 -- 50,554,496(+) GGGAA(A/G)TTGGG intron-variant
rs886494 -- 50,554,584(+) GTGGC(C/G)TGTCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SPATA20 Gene

Variant ID Type Subtype PubMed ID
nsv908600 CNV Gain 21882294
dgv3229n71 CNV Loss 21882294
nsv833477 CNV Loss 17160897
dgv3230n71 CNV Loss 21882294
nsv908605 CNV Loss 21882294
esv2625984 CNV Deletion 19546169

Relevant External Links for SPATA20 Gene

HapMap Linkage Disequilibrium report
SPATA20

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SPATA20 Gene

Disorders for SPATA20 Gene

No disorders were found for SPATA20 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for SPATA20 Gene

Publications for SPATA20 Gene

  1. Cloning and characterization of rat spermatid protein SSP411: a thioredoxin-like protein. (PMID: 15223837) Shi H.J. … Chen C.L. (J. Androl. 2004) 3 23
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Transcriptome analysis of human gastric cancer. (PMID: 16341674) Oh J.H. … Kim N.S. (Mamm. Genome 2005) 3

Products for SPATA20 Gene

Sources for SPATA20 Gene

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