SPATA19 Gene
protein-coding GIFtS: 38
GCID: GC11M133710
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spermatogenesis associated 19
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Aliases
for SPATA19 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Spermatogenesis Associated 191 2 | | Spergen 12 | | CT1321 2 | | Spergen-13 | | SPAS11 2 | | Spermatogenesis-Associated Protein 19, Mitochondrial2 | | Spergen11 | | Spermatogenic Specific-Gene12 | | Spermatogenic Cell-Specific Gene 1 Protein2 3 | | SPERGEN13 | | FLJ258511 | | Spergen-13 | | Cancer/Testis Antigen 1322 | | |
Export aliases for SPATA19 gene to outside databasesPrevious GC identifers: GC11M133216 GC11M129665 |
Summaries
for SPATA19 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: SPT19_HUMAN, Q7Z5L4Function: May have a role in spermiogenesis
|
Genomic Views
for SPATA19 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_033899.8
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SPATA19 gene promoter:
RP58 Tal-1 IRF-1 E47 C/EBPalpha CHOP-10 MEF-2A POU2F1 POU2F1a aMEF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for SPATA19
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SPATA19 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q25 Ensembl cytogenetic band: 11q25 HGNC cytogenetic band: 11q25SPATA19 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M133710: view genomic region
(about GC identifiers)
Start:
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133,710,517 bp from pter |
End:
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133,715,433 bp from pter |
Size:
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4,917 bases |
Orientation:
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minus strand |
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Proteins
for SPATA19 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SPT19_HUMAN, Q7Z5L4 (See
protein sequence)Recommended Name: Spermatogenesis-associated protein 19, mitochondrial precursor Size: 167 amino acids; 19186 Da
Subcellular location: Mitochondrion outer membrane (By similarity)
Secondary accessions: Q8N7A9Explore the universe of human proteins at neXtProt for SPATA19: NX_Q7Z5L4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q7Z5L4
SPATA19 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_777587.1
ENSEMBL proteins: ENSP00000299140 ENSP00000435248
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005741 | mitochondrial outer membrane |
IEA | -- |
SPATA19 for ontologies About GeneDecksing
SPATA19 Antibody Products:
Assay Products for SPATA19: |
Protein
Domains /
Families
for SPATA19 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q7Z5L4 |
Function
for SPATA19 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SPT19_HUMAN, Q7Z5L4Function: May have a role in spermiogenesis
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SPATA19 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SPATA19
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SPATA19 (NM_174927) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SPATA19 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPATA19 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPATA19 |
|
Pathways & Interactions
for SPATA19 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SPATA19
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007275 | multicellular organismal development |
IEA | -- | | GO:0007283 | spermatogenesis |
IEA | -- | | GO:0030154 | cell differentiation |
IEA | -- |
SPATA19 for ontologies About GeneDecksing
|
Drugs & Compounds
for SPATA19 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SPATA19
Search CenterWatch for drugs/clinical trials and news about SPATA19 / SPT19
|
Transcripts
for SPATA19 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SPATA19 gene: NM_174927.1 Unigene Cluster for SPATA19: Spermatogenesis associated 19 Hs.97541 [show with all ESTs]Unigene Representative Sequence: BC0580392 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000299140(uc001qgv.1) ENST00000532889
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SPATA19 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SPATA19
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SPATA19 (NM_174927) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SPATA19 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPATA19 |
Additional cDNA sequence: AF521713.1 AK098717.1 BC058039.1 2 DOTS entries: DT.75100101 DT.108074 16 AceView cDNA sequences: AA910621 NM_174927 AA746627 AK098717 BC058039 AI208905 BX096445 AA398848 AA861875 AA861337 AA435892 BX369285 AF521713 AI024568 BX338140 BU852877
GeneLoc Exon Structure
|
Expression
for SPATA19 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SPATA19 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CGACAGTGTC
About this image
See SPATA19 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SPATA19
SOURCE GeneReport for Unigene cluster: Hs.97541
UniProtKB/Swiss-Prot: SPT19_HUMAN, Q7Z5L4Tissue specificity: Expressed specifically in testis
SABiosciences Custom PCR Arrays for SPATA19
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SPATA19
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SPATA19 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SPATA19 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SPATA19 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPATA19 |
Orthologs
for SPATA19 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for SPATA19 gene from 1/6 species (see all 6) About this table
ENSEMBL Gene Tree for SPATA19 (if available)
TreeFam Gene Tree for SPATA19 (if available) |
Paralogs
for SPATA19 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for SPATA19 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SPATA19 (133710517 - 133715433 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SPATA19: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SPATA19 |
|
Disorders
/ Diseases
for SPATA19 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SPATA19 for disorders About GeneDecksing
OMIM gene information: 609805
OMIM disorders: --
8  diseases for SPATA19: About MalaCardsspastic paraplegia legionnaires' disease paraplegia basal cell carcinoma
spasticity prostate cancer prostatitis carcinoma
Export disorders for SPATA19 gene to outside databases
|
Publications
for SPATA19 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SPATA19 gene integrated from 9 sources:
(articles sorted by number of sources associating them with SPATA19) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Isolation and expression analysis of the human testis-specific gene, SPERGEN-1, a spermatogenic cell-specific gene-1. (PubMed id 12688595)1, 2 Miyamoto T.... Ishikawa M. (2003)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Elevated expression levels of testis-specific genes T EX101 and SPATA19 in basal cell carcinoma and their correlation with clinical a nd pathological features. (PubMed id 19886887)1 Ghafouri-Fard S....Modarressi M.H. (2010)
- Expression of two testis-specific genes, SPATA19 and LEMD1, in prostate cancer. (PubMed id 20682177)1 Ghafouri-Fard S....Modarressi M.H. (2010)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1 Olsen J.V....Mann M. (2006)
- Large-scale characterization of HeLa cell nuclear phosphoproteins. (PubMed id 15302935)1 Beausoleil S.A....Gygi S.P. (2004)
- Cloning and characterization of a mouse spergen-1 localized in sperm mitochondria. (PubMed id 15139970)1 Matsuoka Y....Nishimune Y. (2004)
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External Searches for SPATA19 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing SPATA19 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SPATA19 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SPATA19 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SPATA19 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for SPATA19 gene:
Search GeneIP for patents involving SPATA19
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SPATA19 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SPATA19 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SPATA19 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SPATA19 | | | OriGene Protein Over-expression Lysate for SPATA19 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SPATA19 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SPATA19 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SPATA19 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SPATA19 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SPATA19 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SPATA19 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SPATA19 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SPATA19 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SPATA19 |
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 |  |  |  | |
| | | | Search Tocris compounds for SPATA19 |
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 | | | SPATA19 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPATA19 |
|  |  |  | | | | Search ThermoFisher Antibodies for SPATA19 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPATA19 |
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