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Aliases for SPATA17 Gene

Aliases for SPATA17 Gene

  • Spermatogenesis Associated 17 2 3 5
  • IQ Motif Containing H 2 3
  • Spermatogenesis-Related Protein 11 3
  • MSRG-11 3
  • MSRG11 3
  • IQCH 3

External Ids for SPATA17 Gene

Previous GeneCards Identifiers for SPATA17 Gene

  • GC01P215871
  • GC01P217804
  • GC01P188479

Summaries for SPATA17 Gene

GeneCards Summary for SPATA17 Gene

SPATA17 (Spermatogenesis Associated 17) is a Protein Coding gene. GO annotations related to this gene include calmodulin binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPATA17 Gene

Genomics for SPATA17 Gene

Regulatory Elements for SPATA17 Gene

Enhancers for SPATA17 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around SPATA17 on UCSC Golden Path with GeneCards custom track

Promoters for SPATA17 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around SPATA17 on UCSC Golden Path with GeneCards custom track

Genomic Location for SPATA17 Gene

217,631,324 bp from pter
217,871,696 bp from pter
240,373 bases
Plus strand

Genomic View for SPATA17 Gene

Genes around SPATA17 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SPATA17 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SPATA17 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SPATA17 Gene

Proteins for SPATA17 Gene

  • Protein details for SPATA17 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Spermatogenesis-associated protein 17
    Protein Accession:
    Secondary Accessions:
    • A5D6N2

    Protein attributes for SPATA17 Gene

    361 amino acids
    Molecular mass:
    43499 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SPATA17 Gene

Proteomics data for SPATA17 Gene at MOPED

Post-translational modifications for SPATA17 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SPATA17 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SPATA17 Gene

Domains & Families for SPATA17 Gene

Protein Domains for SPATA17 Gene

Suggested Antigen Peptide Sequences for SPATA17 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 3 IQ domains.
  • Contains 3 IQ domains.
genes like me logo Genes that share domains with SPATA17: view

No data available for Gene Families for SPATA17 Gene

Function for SPATA17 Gene

Phenotypes for SPATA17 Gene

genes like me logo Genes that share phenotypes with SPATA17: view

Animal Model Products

CRISPR Products

miRNA for SPATA17 Gene

miRTarBase miRNAs that target SPATA17

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SPATA17 Gene

Localization for SPATA17 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SPATA17 Gene


Subcellular locations from

Jensen Localization Image for SPATA17 Gene COMPARTMENTS Subcellular localization image for SPATA17 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for SPATA17 Gene

Pathways & Interactions for SPATA17 Gene

SuperPathways for SPATA17 Gene

No Data Available

Interacting Proteins for SPATA17 Gene

Gene Ontology (GO) - Biological Process for SPATA17 Gene


No data available for Pathways by source and SIGNOR curated interactions for SPATA17 Gene

Drugs & Compounds for SPATA17 Gene

No Compound Related Data Available

Transcripts for SPATA17 Gene

Unigene Clusters for SPATA17 Gene

Spermatogenesis associated 17:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SPATA17 Gene

No ASD Table

Relevant External Links for SPATA17 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SPATA17 Gene

mRNA expression in normal human tissues for SPATA17 Gene

mRNA differential expression in normal tissues according to GTEx for SPATA17 Gene

This gene is overexpressed in Testis (x26.8).

Protein differential expression in normal tissues from HIPED for SPATA17 Gene

This gene is overexpressed in Liver (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SPATA17 Gene

SOURCE GeneReport for Unigene cluster for SPATA17 Gene Hs.171130

genes like me logo Genes that share expression patterns with SPATA17: view

Protein tissue co-expression partners for SPATA17 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for SPATA17 Gene

Orthologs for SPATA17 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SPATA17 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SPATA17 35
  • 83.47 (n)
  • 82.55 (a)
(Canis familiaris)
Mammalia SPATA17 35
  • 87.07 (n)
  • 83.93 (a)
SPATA17 36
  • 83 (a)
(Mus musculus)
Mammalia Spata17 35
  • 77.38 (n)
  • 76.18 (a)
Spata17 16
Spata17 36
  • 72 (a)
(Pan troglodytes)
Mammalia SPATA17 35
  • 99.63 (n)
  • 99.17 (a)
SPATA17 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Spata17 35
  • 76.64 (n)
  • 75.62 (a)
(Monodelphis domestica)
Mammalia SPATA17 36
  • 65 (a)
(Ornithorhynchus anatinus)
Mammalia SPATA17 36
  • 52 (a)
(Gallus gallus)
Aves SPATA17 35
  • 67.22 (n)
  • 57.89 (a)
SPATA17 36
  • 58 (a)
(Anolis carolinensis)
Reptilia SPATA17 36
  • 52 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia spata17 35
  • 62.41 (n)
  • 56.53 (a)
(Danio rerio)
Actinopterygii spata17 35
  • 54.65 (n)
  • 49.01 (a)
spata17 36
  • 48 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 43 (a)
Species with no ortholog for SPATA17:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SPATA17 Gene

Gene Tree for SPATA17 (if available)
Gene Tree for SPATA17 (if available)

Paralogs for SPATA17 Gene Pseudogenes for SPATA17 Gene

genes like me logo Genes that share paralogs with SPATA17: view

No data available for Paralogs for SPATA17 Gene

Variants for SPATA17 Gene

Sequence variations from dbSNP and Humsavar for SPATA17 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
VAR_051382 -
rs875312 -- 217,831,669(+) ATTAT(A/G)TATTC intron-variant
rs875872 -- 217,832,709(-) CACCT(C/T)GACCT intron-variant
rs958431 -- 217,865,636(-) TAAAA(C/G)GATGG intron-variant
rs976635 -- 217,824,020(+) GCAGC(A/T)CATAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SPATA17 Gene

Variant ID Type Subtype PubMed ID
nsv873181 CNV Gain 21882294
nsv873182 CNV Loss 21882294
esv274293 CNV Insertion 20981092
esv268142 CNV Insertion 20981092
nsv873183 CNV Loss 21882294
nsv873184 CNV Loss 21882294
nsv468183 CNV Loss 19166990
nsv873185 CNV Loss 21882294
nsv873186 CNV Loss 21882294
esv272605 CNV Insertion 20981092
esv268852 CNV Insertion 20981092
esv2722940 CNV Deletion 23290073
esv2674631 CNV Deletion 23128226
esv989721 CNV Deletion 20482838
esv1474893 CNV Deletion 17803354
esv8865 CNV Loss 19470904
esv1000763 CNV Insertion 20482838
nsv873187 CNV Loss 21882294
esv272752 CNV Insertion 20981092
esv269446 CNV Insertion 20981092
esv1410169 CNV Insertion 17803354
nsv523504 CNV Loss 19592680

Variation tolerance for SPATA17 Gene

Residual Variation Intolerance Score: 55.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.03; 60.42% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for SPATA17 Gene

Disorders for SPATA17 Gene

Relevant External Links for SPATA17

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SPATA17 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SPATA17 Gene

Publications for SPATA17 Gene

  1. Identification of novel candidate loci for anorexia nervosa at 1q41 and 11q22 in Japanese by a genome-wide association analysis with microsatellite markers. (PMID: 19680270) Nakabayashi K. … Shirasawa S. (J. Hum. Genet. 2009) 3 48 67
  2. Expression and identification of a novel apoptosis gene Spata17 (MSRG-11) in mouse spermatogenic cells. (PMID: 16395525) Deng Y. … Lu G.X. (Acta Biochim. Biophys. Sin. (Shanghai) 2006) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. Overexpression of human SPATA17 protein induces germ cell apoptosis in transgenic male mice. (PMID: 23079716) Nie D.S. … Yang X. (Mol. Biol. Rep. 2013) 3
  5. A single nucleotide polymorphism in SPATA17 may be a genetic risk factor for Japanese patients with meiotic arrest. (PMID: 19483714) Miyamoto T. … Sengoku K. (Asian J. Androl. 2009) 3

Products for SPATA17 Gene

Sources for SPATA17 Gene