SPATA13 Gene
protein-coding GIFtS : 53 GCID: GC13 P024734
spermatogenesis associated 13
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Aliasesfor SPATA13 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Spermatogenesis Associated 13 1 2 FLJ312081 ARHGEF291 2 Adenomatous Polyposis Coli Stimulated Exchange Factor 22 APC-Stimulated Guanine Nucleotide Exchange Factor 22 3 Spermatogenesis-Associated Protein 132 ASEF22 5 Asef23
Export aliases for SPATA13 gene to outside databases Previous GC identifers: GC13P022532 GC13P023632 GC13P005546
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Summariesfor SPATA13 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section UniProtKB/Swiss-Prot: SPT13_HUMAN, Q96N96 Function : Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migrationand adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Genomic Viewsfor SPATA13 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000013.10 NC_018924.1 NT_024524.14 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the SPATA13 gene promoter:AREB6 LHX3b/Lhx3b POU2F1 AML1a FOXJ2 (long isoform) POU2F1a LHX3a/Lhx3a FOXJ2 HNF-3beta HNF-4alpha1 Other transcription factors Search SABiosciences Chromatin IP Primers for SPATA13 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 13q12.12 Ensembl cytogenetic band: 13q12.12 HGNC cytogenetic band: 13q12.13 SPATA13 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 13 GeneLoc Exon Structure
GeneLoc location for GC13P024734: view genomic region
(about GC identifiers )
Start: 24,734,861 bp from pter End:
24,896,096 bp from pter
Size: 161,236 bases Orientation:
plus strand
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Proteinsfor SPATA13 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: SPT13_HUMAN, Q96N96 See
protein sequence )Recommended Name: Size : 652 amino acids; 74820 DaSubunit : Interacts (via ABR and SH3 domain) with APC. The binding of APC enhances its GEF activity by relieving it froman autoinhibitory conformation, in which the ABR and SH3 domains are associated with the C-terminal tail. Interacts (via C-terminal tail) with PPP1R9B (via C-terminus). Interacts with RAC1
Subcellular location : Cytoplasm. Cell projection, filopodium. Cell projection, lamellipodium. Cell projection, rufflemembrane. Note=Accumulates in the lamellipodium and ruffle membrane in response to hepatocyte growth factor (HGF) treatment
Sequence caution : Sequence=BAC04977.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Secondary accessions : A2VEA9 A6NF85 B4DQB1 B4DSZ0 B4DVM8 Q5VX68 Q6ZML1 Q8N873 Q8TEK6Alternative splicing : 5 isoforms : Q96N96-1 Q96N96-2 Q96N96-3 Q96N96-4 Q96N96-5 Explore the universe of human proteins at neXtProt for SPATA13: NX_Q96N96 SPATA13 Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins (2 alternative transcripts): NP_001159743.1 NP_694568.1 ENSEMBL proteins: ENSP00000371527 ENSP00000398560 ENSP00000371576 ENSP00000401605 ENSP00000382830 ENSP00000386471 ENSP00000397498 ENSP00000371542 ENSP00000343631 Human Recombinant Protein Products for SPATA13: Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6 ): About this table
About GeneDecksing SPATA13 Antibody Products: Assay Products for SPATA13:
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Protein
Domains /for SPATA13 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section About GeneDecksing 4 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry Q96N96 ProtoNet protein and cluster: Q96N96
4 Blocks protein families : IPB000219 IPB000221 IPB001452 IPB001849 UniProtKB/Swiss-Prot: SPT13_HUMAN, Q96N96 Domain : The C-terminal tail is required for its GEF activitySimilarity : Contains 1 DH (DBL-homology) domainSimilarity : Contains 1 PH domainSimilarity : Contains 1 SH3 domain
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Functionfor SPATA13 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Molecular Function: UniProtKB/Swiss-Prot Summary: SPT13_HUMAN, Q96N96 Function : Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migrationand adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression Enzyme regulation : Both the ABR and the SH3 domains contribute to maintaining the protein in an inhibited conformationby associating with the C-terminal tail. Binding of these domains to the C-terminal tail inhibits the activity of the protein by blocking a region that is required for its GEF activity
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view) : About this table
About GeneDecksing Phenotypes: 1 GenomeRNAi human phenotype for SPATA13 :Animal Models: Clone Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 3 )human mouse rat see all 2 )OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 2 ): SPATA13 (NM_153023 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SPATA13 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat SPATA13
In Situ AssayAdvanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPATA13
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Pathways & Interactionsfor SPATA13 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Unified GeneCards pathways About this table See pathways by source Super-pathway contained gene-specific pathways 1 G-protein signaling Regulation of RAC1 activity 2 Regulation of CDC42 activity 3 Regulation of RAC1 activity
Pathway sources See GeneCards unified pathways Show all pathways 1 1 2 About GeneDecksing Interactions: SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SPATA13 STRING Interaction
Network Preview (showing 4 interactants - click image to see more details)4 Interacting proteins for SPATA13 (ENSP00000371527 4 via UniProtKB, MINT, STRING , and/or I2D About this table Gene Ontology (GO): 5 biological process terms (GO ID links to tree view) : About this table
About GeneDecksing
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Drugs & Compoundsfor SPATA13 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for SPATA13 SPATA13 / SPT13
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Transcriptsfor SPATA13 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,EMD Millipore ,
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for SPATA13 gene (2 alternative transcripts): NM_001166271.1 NM_153023.2 Unigene Cluster for SPATA13:
Spermatogenesis associated 13 Hs.595391 [show with all ESTs ] Unigene Representative Sequence: BX648244 13 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000466831 (uc001upf.2 ) ENST00000382095 (uc010tcy.1 ) ENST00000424834 ENST00000382141 (uc001upe.3 ) ENST00000474317 ENST00000434675 (uc001upi.1 )ENST00000494772 ENST00000399949 ENST00000409126 ENST00000454083 ENST00000488060 ENST00000382108 (uc001upd.2 uc021rhg.1 uc001upg.2 uc010tcz.2 uc010tdb.2 uc010tda.2 uc001uph.3 uc009zzz.2 )ENST00000343003 Clone OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 3 )human mouse rat see all 2 )OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 2 ): SPATA13 (NM_153023 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SPATA13 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat SPATA13
Additional cDNA sequence: AK025586.1 AK055770.1 AK074117.1 AK092754.1 AK092759.1 AK097217.1 AK123031.1 AK123225.1 AK160371.1 AK297394.1 AK298717.1 AK299981.1 AK301149.1 AK307528.1 AL049335.1 BC109290.1 BC109291.1 BX648244.1
11 DOTS entries : DT.97819804 DT.445572
DT.99951324 DT.99928031 DT.101971151 DT.120762087 DT.40260656 DT.97858912 DT.102821355 DT.91653670 DT.97812159 24/228 AceView cDNA sequences (see all 228 ):
AA159751 AI435823 CB215619 AA250723 BQ717547 CK905109 AK123225 D79329 AK097217 CB136185 CD678459 BE735417 BX644087 AA732279 AK092759 BX107153 AK123031 BE856262 CD723650 AW075731 BU742194 AK055770 NM_153023 AL699742 GeneLoc Exon Structure 5/17 Alternative Splicing Database (ASD) splice patterns (SP) for SPATA13 (see all 17 ) About this scheme ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b · 6c ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11a · 11b · 11c ^ 12 ^ 13a · 13b ^ 14 ^ 15a · 15b ^ 16a · SP1 : - - - - - - - SP2 : - - - - SP3 : - - - - SP4 : - SP5 :
ExUns: 16b · 16c ^ 17a · 17b ^ 18a · 18b · 18c ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25a · 25b · 25c · 25d SP1 : - - - - - - - - SP2 : - SP3 : SP4 : SP5 :
ECgene alternative splicing isoforms for SPATA13
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Expression for SPATA13 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section SPATA13 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: ACTGATCTTGAbout this image SPATA13 expression in embryonic tissues and stem cells About this table
1 LifeMap In Vivo Development Anatomical Compartment/CellTissue Category (developmental path) Neural Tube Telencephalon Neural Tube Expression: Experimental details:
In-situ hybridization
See SPATA13 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for SPATA13 SOURCE GeneReport for Unigene cluster: Hs.595391 UniProtKB/Swiss-Prot: SPT13_HUMAN, Q96N96 Tissue specificity : Expressed at high levels in the placenta, spleen and kidney, at moderate levels in lung, smallintestine, liver, brain and heart, and at low levels in skeletal muscle. Expression is aberrantly enhanced in most colorectal tumors SABiosciences Custom PCR Arrays for SPATA13 Primer OriGene genome-wide validated SYBR primer pairs in human mouse rat Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat In Situ Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPATA13
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Orthologsfor SPATA13 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section Orthologs for SPATA13 gene from 4/17 species (see all 17 ) About this table
Organism
Taxonomic
Gene
Description
Human
Orthology
Details
chicken Aves SPATA131
spermatogenesis associated 13
68.72(n) 66.93(a)
418940 XM_417134.2 XP_417134.2
lizard Reptilia SPATA136
--
81(a)
1 ↔ 1
3(188887299-188919272)
zebrafish Actinopterygii Dr.140432
Transcribed sequence with weak similarity to protein more
73.66(n)
BI844434.1
fruit fly Insecta RhoGEF36
--
6(a)
1 → many
3L(277437-305292)
ENSEMBL Gene Tree for SPATA13 (if available)TreeFam Gene Tree for SPATA13 (if available)
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Paralogsfor SPATA13 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for SPATA13 gene ARHGEF6 2 VAV1 2 PLEKHG2 2 PLEKHG3 2 PREX2 2 ARHGEF7 2 TIAM1 2 TIAM2 2 ARHGEF9 2 VAV3 2 VAV2 2 ARHGEF4 2 PLEKHG1 2 PREX1 2 6 SIMAP similar genes for SPATA13 using alignment to 7 protein entries: SPT13_HUMAN (see all proteins ):DKFZp434G2016 ARHGEF9 ARHGEF4 ARHGEF7 SH3GL2 PREX2 About GeneDecksing
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Genomic Variantsfor SPATA13 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical Chr 13 pos Sequence # AA Type More # Allele Pop Total More
HapMap Linkage Disequilibrium report for SPATA13 (24734861 - 24896096 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 5 variations for SPATA13 4 CNVs 8747 5317 5315 9216 1 Indel 71696 Human Gene Mutation Database (HGMD) : SPATA13 SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human mouse rat
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Disorders
/ Diseasesfor SPATA13 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section About GeneDecksing OMIM gene information: 613324
OMIM disorders : --3 : About MalaCards adenomatous polyposis coli polyposis adenoma Human Genome Epidemiology (HuGE) Navigator: SPATA13 (1 document)Export disorders for SPATA13 gene to outside databases
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Publicationsfor SPATA13 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for SPATA13 gene, integrated from 9 sources (see all 16 ):(articles sorted by number of sources associating them with SPATA13) Utopia : connect your pdf to the dynamic
Asef2 and Neurabin2 cooperatively regulate actin cytoskeletal organization and are involved in HGF-induced cell migration. (PubMed id 19151759) 1 , 2 (2009) The Rho-family GEF Asef2 activates Rac to modulate ad hesion and actin dynamics and thereby regulate cell migration. (PubMed id 19934221) 1 , 2 (2009) Identification and characterization of Asef2, a guanine-nucleotide exchange factor specific for Rac1 and Cdc42. (PubMed id 17599059) 1 , 2 (2007) Asef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation element. (PubMed id 17145773) 1 , 2 (2007) The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823) 1 , 2 (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 (2004) Genome-wide association study of comorbid depressive s yndrome and alcohol dependence. (PubMed id 22064162) 1 (2012) Genome wide study of maternal and parent-of-origin eff ects on the etiology of orofacial clefts. (PubMed id 22419666) 1 (2012) Comprehensive analysis of interactions between the Src -associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome. (PubMed id 22745667) 1 (2012)
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
External Searches for SPATA13 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Genome Databases showing SPATA13 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Other Databases showing SPATA13 gene
(According to HUGE )
About This Section --
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Specialized Databases showing SPATA13 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description PharmGKB entry for SPATA13 Pharmacogenomics, SNPs, Pathways
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
About This Section Patent Information for SPATA13 gene: SPATA13 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Productsfor SPATA13 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
Browse OriGene Antibodies OriGene shRNA RFP for SPATA13 OriGene 29mer shRNA kits in GFP-retroviral vector in human mouse rat OriGene genome-wide validated SYBR primer pairs in human mouse rat OriGene Protein Over-expression Lysate for SPATA13 Browse OriGene Fluorogenic Cell Assay Kits Browse OriGene siRNAs OriGene 3'-UTR Clone for SPATA13 OriGene untagged cDNA clones in CMV expression vector in human mouse rat OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for SPATA13 OriGene Custom Protein Services for SPATA13 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SPATA13 QIAGEN SeqTarget long-range PCR primers in human mouse rat QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat
Search Tocris compounds for SPATA13
SPATA13 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPATA13
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat SPATA13
Jump to Section...
Aliases for SPATA13
Databases for SPATA13
Disorders / Diseases for SPATA13
Domains / Families for SPATA13
Drugs / Compounds for SPATA13
Expression for SPATA13
Function for SPATA13
Genomic Views for SPATA13
Intellectual Property for SPATA13
Orthologs for SPATA13
Paralogs for SPATA13
Pathways / Interactions for SPATA13
Products for SPATA13
Proteins for SPATA13
Publications for SPATA13
Search Box for SPATA13
Summaries for SPATA13
Transcripts for SPATA13
Variants for SPATA13
TOP
BOTTOM
Browse Tocris compounds for 
Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine 
Anatomical Compartment 
Negative
Selective marker
Curated
Microarrays
