SPATA12 Gene
protein-coding GIFtS: 36
GCID: GC03P057069
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spermatogenesis associated 12
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Aliases
for SPATA12 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Spermatogenesis Associated 121 2 | | SRG52 3 5 | | Spermatogenesis-Related Protein 52 3 | | Spermatogenesis-Associated Protein 122 |
Export aliases for SPATA12 gene to outside databasesPrevious GC identifer: GC03P057051 |
Summaries
for SPATA12 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for SPATA12 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_022517.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SPATA12 gene promoter:
c-Fos Bach1 USF1 NF-1 AP-1 AML1a USF-1 Sox9 ATF6
Other transcription factors
Search SABiosciences Chromatin IP Primers for SPATA12
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SPATA12 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3p14.3 Ensembl cytogenetic band: 3p14.3 HGNC cytogenetic band: 3p21.2SPATA12 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03P057069: view genomic region
(about GC identifiers)
Start:
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57,094,469 bp from pter |
End:
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57,109,460 bp from pter |
Size:
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14,992 bases |
Orientation:
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plus strand |
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Proteins
for SPATA12 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SPT12_HUMAN, Q7Z6I5 (See
protein sequence)Recommended Name: Spermatogenesis-associated protein 12 Size: 190 amino acids; 20418 Da
Secondary accessions: A0AVA8 B2RMW1Explore the universe of human proteins at neXtProt for SPATA12: NX_Q7Z6I5
SPATA12 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_859078.1
ENSEMBL proteins: ENSP00000335392
Human Recombinant Protein Products for SPATA12:
SPATA12 Antibody Products:
Assay Products for SPATA12: |
Protein
Domains /
Families
for SPATA12 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q7Z6I5 |
Function
for SPATA12 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SPATA12
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SPATA12
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SPATA12 (NM_181727) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SPATA12 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPATA12 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPATA12 |
|
Pathways & Interactions
for SPATA12 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SPATA12
|
Drugs & Compounds
for SPATA12 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SPATA12
Search CenterWatch for drugs/clinical trials and news about SPATA12 / SPT12
|
Transcripts
for SPATA12 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SPATA12 gene: NM_181727.1 Unigene Cluster for SPATA12: Spermatogenesis associated 12 Hs.129794 [show with all ESTs]Unigene Representative Sequence: AY2211171 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000334325(uc003dij.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SPATA12
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SPATA12
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SPATA12 (NM_181727) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SPATA12 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPATA12 |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SPATA12
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat SPATA12 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SPATA12 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SPATA12 |
Additional cDNA sequence: AY221117.1 BC033337.1 BC126274.1 BC136498.1 1 DOTS entry: DT.100657160 18 AceView cDNA sequences: AI655432 AY221117 AA620849 AA412127 NM_181727 BX097694 BM552714 AI142295 AI201065 BC033337 BG773323 AA861020 AI148004 CA422527 AI651335 AA993431 BF874493 BF996807
GeneLoc Exon Structure
|
Expression
for SPATA12 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SPATA12 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTCATTCCCC
About this image
See SPATA12 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SPATA12
SOURCE GeneReport for Unigene cluster: Hs.129794
UniProtKB/Swiss-Prot: SPT12_HUMAN, Q7Z6I5Tissue specificity: Expressed in testis
SABiosciences Custom PCR Arrays for SPATA12
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SPATA12
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat SPATA12 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SPATA12 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SPATA12 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPATA12 |
Orthologs
for SPATA12 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for SPATA12 (if available)
TreeFam Gene Tree for SPATA12 (if available) |
Paralogs
for SPATA12 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for SPATA12 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SPATA12 |
|
Disorders
/ Diseases
for SPATA12 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SPATA12 for disorders About GeneDecksing
OMIM gene information: 609869
OMIM disorders: --
2  diseases for SPATA12: About MalaCardssertoli cell-only syndrome cryptorchidism
Export disorders for SPATA12 gene to outside databases
|
Publications
for SPATA12 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SPATA12 gene integrated from 9 sources:
(articles sorted by number of sources associating them with SPATA12) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification and expression of a novel human testis-specific gene by digital differential display. (PubMed id 15603706)1, 2, 9 Li D. and Lu G.X. (2004)
- Transcriptional regulation of human novel gene SPATA12 promoter by AP-1 and HSF. (PubMed id 22981541)1, 3 Li D....Liu X. (2012)
- Expression and possible functions of a novel gene SPATA12 in human testis. (PubMed id 17251597)1, 3 Dan L....Guangxiu L. (2007)
- Molecular cloning and expression analysis of a novel human testis- specific gene. (PubMed id 15490870)1, 2 Li D.... Liu G. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for SPATA12 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing SPATA12 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SPATA12 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SPATA12 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SPATA12 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SPATA12 gene:
Search GeneIP for patents involving SPATA12
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SPATA12 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SPATA12 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SPATA12 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SPATA12 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SPATA12 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SPATA12 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SPATA12 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SPATA12 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SPATA12 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SPATA12 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SPATA12 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SPATA12 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SPATA12 |
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| | | | Search Tocris compounds for SPATA12 |
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 | | | SPATA12 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPATA12 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for SPATA12 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPATA12 |
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