Aliases for SPARCL1 Gene
Aliases for SPARCL1 Gene
External Ids for SPARCL1 Gene
- HGNC: 11220
- Entrez Gene: 8404
- Ensembl: ENSG00000152583
- OMIM: 606041
- UniProtKB: Q14515
Previous GeneCards Identifiers for SPARCL1 Gene
- GC04M088552
- GC04M088696
- GC04M088852
- GC04M088751
- GC04M088613
- GC04M088394
- GC04M084140
Summaries for SPARCL1 Gene
GeneCards Summary for SPARCL1 Gene
SPARCL1 (SPARC Like 1) is a Protein Coding gene. Diseases associated with SPARCL1 include Klatskin's Tumor. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is SPARC.
Additional gene information for SPARCL1 Gene
- Monarch Initiative
- Search for SPARCL1 at DataMed
- Search for SPARCL1 at HumanCyc
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SPARCL1 Gene
Genomics for SPARCL1 Gene
GeneHancer (GH) Regulatory Elements for SPARCL1 Gene
Promoters and enhancers for SPARCL1 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH04I087524 | Promoter/Enhancer | 1.8 | EPDnew FANTOM5 Ensembl ENCODE dbSUPER | 569.5 | +2.9 | 2877 | 6.6 | HLF REST RAD21 NR2F2 YY1 CBX5 ZSCAN16 SCRT2 HNF4A PRDM10 | SPARCL1 DMP1 ENSG00000272856 MEPE LOC105377322 | |
| GH04I087531 | Enhancer | 0.4 | dbSUPER | 556.6 | -1.2 | -1218 | 0.8 | MITF ZNF548 | SPARCL1 RPL6P13 DSPP | |
| GH04I087520 | Enhancer | 1.5 | FANTOM5 Ensembl ENCODE dbSUPER | 14.7 | +9.6 | 9557 | 2.6 | PKNOX1 ZSCAN4 INSM2 FEZF1 ZNF366 ZSCAN5C ZNF350 ATF7 FOS ZNF362 | LOC105377322 SPARCL1 DMP1 DSPP | |
| GH04I087488 | Enhancer | 0.7 | dbSUPER | 19.2 | +40.8 | 40824 | 2.8 | FOXA2 MAX CEBPG RAD21 YY1 HNF4G NFE2 RXRA HLF CEBPB | SPARCL1 ENSG00000272856 LOC105377321 LOC105377322 | |
| GH04I087555 | Enhancer | 0.7 | Ensembl ENCODE | 17.6 | -25.0 | -25028 | 1.2 | ZNF639 SP1 JUND NFE2 FOSL2 FOS | SPARCL1 DSPP |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around SPARCL1 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for SPARCL1 Gene
Genomic Locations for SPARCL1 Gene
- chr4:87,473,330-87,531,061
- (GRCh38/hg38)
- Size:
- 57,732 bases
- Orientation:
- Minus strand
- chr4:88,394,487-88,452,213
- (GRCh37/hg19)
Genomic View for SPARCL1 Gene
Genes around SPARCL1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 4q22.1 by Ensembl
- 4q22.1 by Entrez Gene
- 4q22.1 by HGNC
SPARCL1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SPARCL1 Gene
Proteins for SPARCL1 Gene
-
Protein details for SPARCL1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q14515-SPRL1_HUMAN
- Recommended name:
- SPARC-like protein 1
- Protein Accession:
- Q14515
- B4E2Z0
- E7ESU2
- Q14800
Protein attributes for SPARCL1 Gene
- Size:
- 664 amino acids
- Molecular mass:
- 75208 Da
- Quaternary structure:
- No Data Available
Protein Expression for SPARCL1 Gene
Post-translational modifications for SPARCL1 Gene
- N- and O-glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.
- Glycosylation at isoforms=31, isoforms=40, isoforms=44, isoforms=116, isoforms=2169, isoforms=2176, posLast=196196, isoforms=2280, isoforms=2331, isoforms=2398, isoforms=2412, and isoforms=2476
Other Protein References for SPARCL1 Gene
Antibody Products
- R&D Systems Antibodies for SPARCL1 (SPARC-like 1/SPARCL1)
-
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-
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-
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-
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Protein Products
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-
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- Sino Biological Recombinant Proteins for SPARCL1
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-
Cloud-Clone Corp. Proteins for SPARCL1
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Assay Products
-
Custom Assay ServicesOriGene ELISA Kits for SPARCL1
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-
Cloud-Clone Corp. Assay Kits for SPARCL1
-
Abcam assays for SPARCL1
- Sino Biological Assays for SPARCL1
No data available for DME Specific Peptides for SPARCL1 Gene
Domains & Families for SPARCL1 Gene
Gene Families for SPARCL1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Plasma proteins
- Predicted intracellular proteins
- Predicted secreted proteins
Protein Domains for SPARCL1 Gene
Suggested Antigen Peptide Sequences for SPARCL1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q14515- Family:
-
- Belongs to the SPARC family.
Function for SPARCL1 Gene
Phenotypes From GWAS Catalog for SPARCL1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005509 | calcium ion binding | IBA | -- |
| GO:0005515 | protein binding | IPI | 20926826 |
| GO:0005518 | collagen binding | IBA | -- |
| GO:0046872 | metal ion binding | IEA | -- |
| GO:0050840 | extracellular matrix binding | IBA | -- |
Phenotypes for SPARCL1 Gene
- MGI mutant phenotypes for SPARCL1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for SPARCL1:
Animal Models for SPARCL1 Gene
- MGI Knock Outs for SPARCL1:
-
- Sparcl1 tm1Pmc
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for SPARCL1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for SPARCL1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for SPARCL1 gene
- Search ViGene Biosciences for SPARCL1
CRISPR Products
-
OriGene CRISPR knockouts for SPARCL1
- genomics-online: gRNA clones - Search results for available SPARCL1 gene related products
- Applied Biological Materials CRISPR for SPARCL1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for SPARCL1
- GenScript: Design CRISPR guide RNA sequences for SPARCL1
miRNA for SPARCL1 Gene
- miRTarBase miRNAs that target SPARCL1
miRNA Products
- Search ViGene Biosciences for SPARCL1
Inhibitory RNA Products
- Origene RNAi, shrna, and sirna products in human, mouse, rat for SPARCL1
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-
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Clone Products
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available SPARCL1 gene related products
- orf clones - Search results for available SPARCL1 gene related products
- Applied Biological Materials Clones for SPARCL1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for SPARCL1
-
ViGene Biosciences adenoviral particle packaged cDNA for SPARCL1 gene
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No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for SPARCL1 Gene
Localization for SPARCL1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SPARCL1 Gene
- Secreted, extracellular space, extracellular matrix.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| endoplasmic reticulum | 4 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IDA | 27068509 |
| GO:0005578 | proteinaceous extracellular matrix | IEA | -- |
| GO:0005615 | extracellular space | HDA,IDA | 16502470 |
| GO:0005788 | endoplasmic reticulum lumen | TAS | -- |
| GO:0070062 | extracellular exosome | IDA,HDA | 23376485 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for SPARCL1 Gene
Pathways & Interactions for SPARCL1 Gene
No Data Available
Interacting Proteins for SPARCL1 Gene
Selected Interacting proteins:
Q14515-SPRL1_HUMAN
ENSP00000282470
for SPARCL1 Gene via
IID
UniProtKB
STRING
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007165 | signal transduction | IEA | -- |
| GO:0043687 | post-translational protein modification | TAS | -- |
| GO:0044267 | cellular protein metabolic process | TAS | -- |
| GO:0048856 | anatomical structure development | IBA | -- |
No data available for Pathways by source and SIGNOR curated interactions for SPARCL1 Gene
Transcripts for SPARCL1 Gene
mRNA/cDNA for SPARCL1 Gene
- (4) REFSEQ mRNAs :
- (14) Additional mRNA sequences :
- (963) Selected AceView cDNA sequences:
- (10) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for SPARCL1 Gene
- SPARC-like 1 (hevin):
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for SPARCL1
- genomics-online: gRNA clones - Search results for available SPARCL1 gene related products
- Applied Biological Materials CRISPR for SPARCL1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for SPARCL1
- GenScript: Design CRISPR guide RNA sequences for SPARCL1
miRNA Products
- Search ViGene Biosciences for SPARCL1
Inhibitory RNA Products
- Origene RNAi, shrna, and sirna products in human, mouse, rat for SPARCL1
- Browse OriGene Inhibitory RNA Products For SPARCL1
- genomics-online: shRNA clones - Search results for available SPARCL1 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for SPARCL1 gene
Clone Products
- Sino Biological Human cDNA Clone for SPARCL1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for SPARCL1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SPARCL1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available SPARCL1 gene related products
- orf clones - Search results for available SPARCL1 gene related products
- Applied Biological Materials Clones for SPARCL1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||||||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | |||||||||||||||||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||||||||||||||
| SP6: | - | ||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | - | - | - | - |
Expression for SPARCL1 Gene
This gene is overexpressed in Cerebrospinal fluid (28.2), Vitreous humor (10.3), Serum (8.5), and Plasma (7.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for SPARCL1 Gene
NURSA nuclear receptor signaling pathways regulating expression of SPARCL1 Gene:
SPARCL1SOURCE GeneReport for Unigene cluster for SPARCL1 Gene:
Hs.62886mRNA Expression by UniProt/SwissProt for SPARCL1 Gene:
Q14515-SPRL1_HUMAN
Tissue specificity:
Highly expressed in lymph node, brain, heart, lung, skeletal muscle, ovary, small intestine, and colon, with lower levels in placenta, pancreas, testis, spleen, and thymus, and no expression in kidney, liver, and peripheral blood leukocytes.
Evidence on tissue expression from TISSUES for SPARCL1 Gene
- Nervous system(5)
- Lung(4.8)
- Heart(4.1)
- Bone marrow(4)
- Intestine(4)
- Stomach(3.4)
- Spleen(3.1)
- Eye(2.7)
- Kidney(2.6)
- Gall bladder(2.5)
- Muscle(2.4)
- Lymph node(2.3)
- Thyroid gland(2.1)
Primer Products
-
OriGene qPCR primer pairs for SPARCL1
-
OriGene qPCR primer pairs and template standards for SPARCL1
- genomics-online: primer clones - Search results for available SPARCL1 gene related products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for SPARCL1 Gene
Orthologs for SPARCL1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | SPARCL1 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | SPARCL1 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | SPARCL1 34 33 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Sparcl1 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Sparcl1 34 16 33 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | SPARCL1 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | SPARCL1 34 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | sparcl1 34 |
|
OneToOne | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP000305 33 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | BM-40-SPARC 33 34 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | ost-1 33 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany |
- Species where no ortholog for SPARCL1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
Paralogs for SPARCL1 Gene
(1) SIMAP similar genes for SPARCL1 Gene using alignment to 10 proteins:
Variants for SPARCL1 Gene
| SNP ID | Clin | Chr 04 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000005938 | -- | 87,512,495(-) | G/T | intron_variant | |
| rs1000040777 | -- | 87,506,978(-) | TTTTTT/TTTTTTT | intron_variant | |
| rs10001608 | -- | 87,516,558(-) | T/C | intron_variant | |
| rs1000242060 | -- | 87,506,229(-) | C/A | intron_variant | |
| rs1000303332 | -- | 87,499,632(-) | A/G | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3601276 | CNV | loss | 21293372 |
| esv3601278 | CNV | loss | 21293372 |
| esv3601279 | CNV | loss | 21293372 |
| nsv1002789 | CNV | loss | 25217958 |
| nsv1011882 | CNV | gain | 25217958 |
Residual Variation Intolerance Score:
71.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.54;
55.73% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SPARCL1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SPARCL1 Gene
Disorders for SPARCL1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| klatskin's tumor |
|
|
Search SPARCL1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for SPARCL1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for SPARCL1 Gene
Publications for SPARCL1 Gene
- Cloning from purified high endothelial venule cells of hevin, a close relative of the antiadhesive extracellular matrix protein SPARC. (PMID: 7600298) Girard JP … Springer TA (Immunity 1995) 2 3 4 22 58
- Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging. (PMID: 19834535) Wheeler HE … Kim SK (PLoS genetics 2009) 3 44 58
- Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene. (PMID: 18384059) Kähler AK … Andreassen OA (American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008) 3 44 58
- Candidate gene analysis of SPARCL1 gene in patients with multiple sclerosis. (PMID: 17825989) Scalabrini D … Galimberti D (Neuroscience letters 2007) 3 44 58
- Matricellular hevin regulates decorin production and collagen assembly. (PMID: 16844696) Sullivan MM … Sage EH (The Journal of biological chemistry 2006) 2 3 58
Products for SPARCL1 Gene
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- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SPARCL1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- GeneTex SPARCL1 antibody for SPARCL1
- Search GeneTex for Proteins for SPARCL1
- ViGene Biosciences adenoviral particle packaged cDNA for SPARCL1 gene
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- Search ViGene Biosciences for SPARCL1
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- Search Santa Cruz Biotechnology (SCBT) for SPARCL1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for SPARCL1
- Horizon Cell Lines for SPARCL1
- genomics-online: cdna clones - Search results for available SPARCL1 gene related products
- orf clones - Search results for available SPARCL1 gene related products
- genomics-online: gRNA clones - Search results for available SPARCL1 gene related products
- genomics-online: primer clones - Search results for available SPARCL1 gene related products
- genomics-online: shRNA clones - Search results for available SPARCL1 gene related products
Sources for SPARCL1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew