SPANXN5 Gene
protein-coding GIFtS: 33
GCID: GC0XM052825
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SPANX family, member N5
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Aliases
for SPANXN5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| SPANX Family, Member N51 2 | | Cancer/Testis Antigen Family 11, Member 102 | | SPANX-N51 2 3 | | Sperm Protein Associated With The Nucleus On The X Chromosome N52 | | CT11.101 2 | | SPANX Family Member N53 | | Nuclear-Associated Protein SPAN-Xn52 3 | | |
Export aliases for SPANXN5 gene to outside databasesPrevious GC identifers: GC0XM052842 GC0XM049890 |
Summaries
for SPANXN5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for SPANXN5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_011630.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SPANXN5 gene promoter:
TBP
Other transcription factors
Search SABiosciences Chromatin IP Primers for SPANXN5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SPANXN5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xp11.22 Ensembl cytogenetic band: Xp11.22 HGNC cytogenetic band: Xp11.22SPANXN5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XM052825: view genomic region
(about GC identifiers)
Start:
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52,825,184 bp from pter |
End:
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52,827,141 bp from pter |
Size:
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1,958 bases |
Orientation:
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minus strand |
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Proteins
for SPANXN5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SPXN5_HUMAN, Q5MJ07 (See
protein sequence)Recommended Name: Sperm protein associated with the nucleus on the X chromosome N5 Size: 72 amino acids; 8277 DaExplore the universe of human proteins at neXtProt for SPANXN5: NX_Q5MJ07
SPANXN5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001009616.1
ENSEMBL proteins: ENSP00000364661
Human Recombinant Protein Products:
SPANXN5 Antibody Products:
Assay Products for SPANXN5: |
Protein
Domains /
Families
for SPANXN5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SPANXN5 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q5MJ07ProtoNet protein and cluster: Q5MJ07 UniProtKB/Swiss-Prot: SPXN5_HUMAN, Q5MJ07Similarity: Belongs to the SPAN-X family |
Function
for SPANXN5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SPANXN5
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SPANXN5
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SPANXN5 (NM_001009616) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SPANXN5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPANXN5 |
|
Pathways & Interactions
for SPANXN5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SPANXN5
|
Drugs & Compounds
for SPANXN5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SPANXN5
Search CenterWatch for drugs/clinical trials and news about SPANXN5 / SPXN5
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Transcripts
for SPANXN5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SPANXN5 gene: NM_001009616.2 Unigene Cluster for SPANXN5: SPANX family, member N5 Hs.535218 Unigene Representative Sequence: NM_0010096161 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000375511(uc004drc.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SPANXN5
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SPANXN5
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SPANXN5 (NM_001009616) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SPANXN5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPANXN5 |
1 DOTS entry: DT.75198048
GeneLoc Exon Structure
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Expression
for SPANXN5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SPANXN5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See SPANXN5 Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.535218
SABiosciences Custom PCR Arrays for SPANXN5
Primer
Products: | | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat SPANXN5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SPANXN5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SPANXN5 |
Orthologs
for SPANXN5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for SPANXN5 (if available)
TreeFam Gene Tree for SPANXN5 (if available) |
Paralogs
for SPANXN5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SPANXN5 gene
- SPANXN22 SPANXN12 SPANXB22 SPANXB12 SPANXD2 SPANXA22 SPANXN32 SPANXC2
- SPANXN42 SPANXA12
12 SIMAP similar genes for SPANXN5 using alignment to 1 protein entry: SPXN5_HUMAN:SPANXN1 SPANXN2 SPANXN3 SPANXN4 SPANXA1 SPANXC
SPANXA2 SPANXD SPANXE SPANXB1 SPANXB2 SPANXF1
SPANXN5 for paralogs About GeneDecksing
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Genomic Variants
for SPANXN5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for SPANXN5 (52825184 - 52827141 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for SPANXN5
1 CNV: 73978
1 Inversion: 37382
Human Gene Mutation Database (HGMD): SPANXN5
| SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for SPANXN5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
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 SPANXN5 for disorders About MalaCards
SPANXN5 for disorders About GeneDecksing
OMIM gene information: 300668
OMIM disorders: --
Export disorders for SPANXN5 gene to outside databases
|
Publications
for SPANXN5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SPANXN5 gene integrated from 9 sources:
(articles sorted by number of sources associating them with SPANXN5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The SPANX gene family of cancer/testis-specific antigens: rapid evolution and amplification in African great apes and hominids. (PubMed id 14973187)1, 2, 3 Kouprina N.... Larionov V. (2004)
- Hominoid-specific SPANXA/D genes demonstrate differential expression in individuals and protein localization to a distinct nuclear envelope domain during spermatid morphogenesis. (PubMed id 17012309)1, 3 Westbrook V.A....Herr J.C. (2006)
- The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (2005)
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External Searches for SPANXN5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing SPANXN5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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Other Databases showing SPANXN5 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SPANXN5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SPANXN5 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for SPANXN5 gene:
Search GeneIP for patents involving SPANXN5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SPANXN5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SPANXN5 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SPANXN5 | | Browse OriGene genome-wide validated SYBR primer pairs | | | OriGene Protein Over-expression Lysate for SPANXN5 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SPANXN5 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SPANXN5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SPANXN5 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SPANXN5 | | OriGene Custom Protein Services for SPANXN5 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SPANXN5 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SPANXN5 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SPANXN5 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SPANXN5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SPANXN5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SPANXN5 |
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 | | | SPANXN5 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for SPANXN5 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPANXN5 |
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