Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



SPANXB2 Gene

protein-coding   GIFtS: 37
GCID: GC0XP140085

SPANX Family, Member B2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
SPANX Family, Member B21 2     SPAN-Xf2
Cancer/Testis Antigen 11.22 3     SPANX2
Nuclear-Associated Protein SPAN-Xb2 3     SPANX-C2
Nuclear-Associated Protein SPAN-Xf2 3     hCG20367082
CT11.22 3     SPAN-Xb Protein2
SPANX-B2 3     SPANX Family Member B12
SPANX-F2 3     Sperm Protein Associated With The Nucleus On The X Chromosome B/F2
SPANXB2 3     Sperm Protein Associated With The Nucleus, X Chromosome, Family Member B22
SPANX Family Member B/F2 3     

External Ids:    HGNC: 143301   Entrez Gene: 1001331712   Ensembl: ENSG000002272347   UniProtKB: Q9NS253   

Export aliases for SPANXB2 gene to outside databases

Previous GC identifers: GC0XU990343 GC0XP138793 GC0XP138795 GC0XM140061 GC0XP139914 GC0XP139915


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for SPANXB2 Gene:
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the
series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature
spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a
cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize
to various subcellular compartments. This particular gene maps to chromosome X in a head-to-tail orientation with
SPANX family member B1 and appears to be a duplication of that locus. The SPANXB genes are unique members of this
gene family, since they contain an additional 18 nt in their coding region compared to the majority of family
members. Although the protein encoded by this gene contains consensus nuclear localization signals, the major
site for subcellular localization of expressed protein is in the cytoplasmic droplets of ejaculated spermatozoa.
This protein provides a biochemical marker for studying the unique structures in spermatazoa, while attempting to
further define its role in spermatogenesis. (provided by RefSeq, Jul 2008)

GeneCards Summary for SPANXB2 Gene:
SPANXB2 (SPANX family, member B2) is a protein-coding gene. Diseases associated with SPANXB2 include male germ cell tumor, and germ cell tumors. An important paralog of this gene is SPANXA2.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:NC_018934.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SPANXB2 gene promoter:
         HFH-3   USF1   CUTL1   POU6F1 (c2)   CREB   FOXI1   POU2F1   POU2F1a   USF-1   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSPANXB2 promoter sequence
   Search Chromatin IP Primers for SPANXB2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SPANXB2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq27.1   Ensembl cytogenetic band:  Xq27.1   HGNC cytogenetic band: Xq27.1

SPANXB2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SPANXB2 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP140085:  view genomic region     (about GC identifiers)

Start:
140,084,756 bp from pter      End:
140,085,871 bp from pter
Size:
1,116 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: SPNXB_HUMAN, Q9NS25 (See protein sequence)
Recommended Name: Sperm protein associated with the nucleus on the X chromosome B/F  
Size: 103 amino acids; 11826 Da
Developmental stage: Detected in round and elongating spermatids
Secondary accessions: B2RPP2 Q32WQ7 Q5JYZ7 Q8TAD5

Explore the universe of human proteins at neXtProt for SPANXB2: NX_Q9NS25

Explore proteomics data for SPANXB2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SPANXB2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_663697.1  
    ENSEMBL proteins: 
     ENSP00000405202  

    SPANXB2 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for SPANXB2
    GenScript Custom Purified and Recombinant Proteins Services for SPANXB2
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SPANXB2

    SPANXB2 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for SPANXB2
    Abcam antibodies for SPANXB2
    Cloud-Clone Corp. Antibodies for SPANXB2
    Search ThermoFisher Antibodies for SPANXB2
    Search LSBio for Antibodies for SPANXB2

    SPANXB2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for SPANXB2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SPANXB2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SPANXB2
    Cloud-Clone Corp. CLIAs for SPANXB2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    1 InterPro protein domain:
     IPR010007 SPANX_prot

    Graphical View of Domain Structure for InterPro Entry Q9NS25

    ProtoNet protein and cluster: Q9NS25

    UniProtKB/Swiss-Prot: SPNXB_HUMAN, Q9NS25
    Similarity: Belongs to the SPAN-X family


    SPANXB2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    SPANXB2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SPANXB2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SPANXB2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SPANXB2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SPANXB2

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat SPANXB2 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate SPANXB2
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SPANXB2
    Predesigned siRNA for gene silencing in human, mouse, rat SPANXB2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SPANXB2

    Clone
    Products:
         
    OriGene clones in human, mouse for SPANXB2 (see all 3)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SPANXB2 (NM_145664)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SPANXB2
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SPANXB2

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SPANXB2
    Browse ESI BIO Cell Lines and PureStem Progenitors for SPANXB2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPANXB2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    SPNXB_HUMAN, Q9NS25: Cytoplasm. Nucleus. Note=Associated with nuclear craters
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol1
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus TAS10906052
    GO:0005737cytoplasm IEA--

    SPANXB2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SPANXB2
    Interactions:

        Search GeneGlobe Interaction Network for SPANXB2

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007286spermatid development NAS10906052

    SPANXB2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SPANXB2 (SPNXB)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for SPANXB2 gene: 
    NM_145664.1  

    Unigene Cluster for SPANXB2:

    SPANX family, member B2
    Hs.434105  [show with all ESTs]
    Unigene Representative Sequence: BG721088
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000449283(uc004fbh.3)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SPANXB2 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate SPANXB2
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SPANXB2
    Predesigned siRNA for gene silencing in human, mouse, rat SPANXB2
    Clone
    Products:
         
    OriGene clones in human, mouse for SPANXB2 (see all 3)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SPANXB2 (NM_145664)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SPANXB2
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SPANXB2
    Primer
    Products:
        
    Browse OriGene qPCR
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat SPANXB2
      QuantiTect SYBR Green Assays in human, mouse, rat SPANXB2
      QuantiFast Probe-based Assays in human, mouse, rat SPANXB2

    Additional mRNA sequence: 

    AF098307.1 AJ457796.1 BC034472.1 BC144689.1 

    4 DOTS entries:

    DT.121301246  DT.99934860  DT.121301248  DT.92424949 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    SPANXB2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SPANXB2 Expression
    About this image

    SPANXB2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SPANXB2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.434105

    UniProtKB/Swiss-Prot: SPNXB_HUMAN, Q9NS25
    Tissue specificity: Detected in testis and sperm

        Custom PCR Arrays for SPANXB2
    Primer
    Products:
    Browse OriGene qPCR
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat SPANXB2
    QuantiTect SYBR Green Assays in human, mouse, rat SPANXB2
    QuantiFast Probe-based Assays in human, mouse, rat SPANXB2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPANXB2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of human and chimp.

    Orthologs for SPANXB2 gene from 1 species (see representative species )    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chimpanzee
    (Pan troglodytes)
    Mammalia --
    Pan troglodytes SPANX A/D member 1 (LOC493981), mR...
    73(a)
    1 → many
    X(141602354-141816913)


    ENSEMBL Gene Tree for SPANXB2 (if available)
    TreeFam Gene Tree for SPANXB2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for SPANXB2 gene
    SPANXA22  SPANXD2  SPANXB12  SPANXC2  SPANXA12  
    9 SIMAP similar genes for SPANXB2 using alignment to 1 protein entry:     SPNXB_HUMAN:
    SPANXC    SPANXA1    SPANXE    SPANXA2    SPANXD    SPANXN1
    SPANXN2    SPANXN5    SPANXN3

    SPANXB2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    5 SNPs for SPANXB2    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs39764421,2
    C,A--140083744(+) ttaatT/Cataac 1 -- us2k11Minor allele frequency- C:0.00NA 2
    rs2017128781,2
    ----140084111(+) AAAAAA/GAGAAA 1 -- us2k10--------
    rs78791661,2
    ----140083935(+) accccA/Gtctct 1 -- us2k10--------
    rs1468706631,2
    ----140084700(+) TGCCAC/TTGGCT 1 -- us2k10--------
    rs2004945741,2
    ----140084105(+) CATTTC/GAAAAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SPANXB2 (140084756 - 140085871 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for SPANXB2 (see all 17):    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv821600CNV Deletion20802225
    nsv7124CNV Insertion18451855
    nsv508805CNV Insertion20534489
    esv1002958CNV Loss20482838
    nsv499192CNV Loss21111241
    nsv510863CNV Loss20534489
    nsv7123CNV Loss18451855
    nsv524931CNV Gain19592680
    nsv433463CNV Gain18776910
    nsv9978CNV Gain18304495

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SPANXB2
    DNA2.0 Custom Variant and Variant Library Synthesis for SPANXB2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    5 diseases for SPANXB2:    
    About MalaCards
    male germ cell tumor    germ cell tumors    infertility    prostate cancer
    prostatitis


    SPANXB2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SPANXB2
    Human Genome Epidemiology (HuGE) Navigator: SPANXB2 (1 document)

    Export disorders for SPANXB2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for SPANXB2 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with SPANXB2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. SPANX gene variation in fertile and infertile males. (PubMed id 20073942)1, 4 Hansen S....Carrell D. (Syst Biol Reprod Med 2010)
    2. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (Nature 2005)
    3. Dynamic structure of the SPANX gene cluster mapped to the prostate cancer susceptibility locus HPCX at Xq27. (PubMed id 16251457)1, 2 Kouprina N.... Larionov V. (Genome Res. 2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. The human SPANX multigene family: genomic organization, alignment and expression in male germ cells and tumor cell lines. (PubMed id 12758128)1, 2 Zendman A.J.... van Muijen G.N.P. (Gene 2003)
    6. Spermatid-specific expression of the novel X-linked gene product SPAN-X localized to the nucleus of human spermatozoa. (PubMed id 10906052)1, 2 Westbrook V.A.... Herr J.C. (Biol. Reprod. 2000)
    7. A shared promoter region suggests a common ancestor for the human VCX/Y, SPANX, and CSAG gene families and the murine CYPT family. (PubMed id 17342728)1 Hansen M.A....Leffers H. (Mol. Reprod. Dev. 2008)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. Differential nuclear localization of the cancer/testis-associated protein, SPAN-X/CTp11, in transfected cells and in 50% of human spermatozoa. (PubMed id 11133693)1 Westbrook V.A....Herr J.C. (Biol. Reprod. 2001)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 100133171 HGNC: 14330 Ensembl:ENSG00000227234 euGenes: HUgn100133171 ECgene: SPANXB2
    H-InvDB: SPANXB2

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for SPANXB2 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for SPANXB2 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for SPANXB2 gene:
    Search GeneIP for patents involving SPANXB2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for SPANXB2  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for SPANXB2  
     Browse OriGene qSTAR qPCR primer pairs   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SPANXB2   OriGene Custom Protein Services for SPANXB2  

     
     
     Block miRNA regulation of human, mouse, rat SPANXB2 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing SPANXB2
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SPANXB2 Predesigned siRNA for gene silencing in human, mouse, rat SPANXB2
     QuantiFast Probe-based Assays in human, mouse, rat SPANXB2 QuantiTect SYBR Green Assays in human, mouse, rat SPANXB2
     Custom PCR Arrays for SPANXB2 Search Chromatin IP Primers for SPANXB2
     Pre-validated RT2 qPCR Primer Assay in human, mouse / rat SPANXB2  Search GeneGlobe Interaction Network for SPANXB2
     Regulatory tfbs in SPANXB2 promoter
     GenScript Custom Purified and Recombinant Proteins Services for SPANXB2 GenScript cDNA clones with any tag delivered in your preferred vector for SPANXB2
     GenScript Custom Assay Services for SPANXB2 GenScript Custom overexpressing Cell Line Services for SPANXB2
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for SPANXB2 (SPNXB)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Biologicals
     Novus Tissue Slides
     Antibodies for SPANXB2
     See all of Abcam's Antibodies, Kits and Proteins for SPANXB2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for SPANXB2
     Antibodies for SPANXB2
     ELISAs for SPANXB2
     CLIAs for SPANXB2



     Browse ESI BIO Cell Lines and PureStem Progenitors for SPANXB2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPANXB2
     Browse SwitchGear 3'UTR luciferase reporter plasmids for SPANXB2
     SwitchGear Promoter luciferase reporter plasmids for SPANXB2
     Search ThermoFisher Antibodies for SPANXB2
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SPANXB2
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SPANXB2
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SPANXB2
     Search LSBio for Antibodies for SPANXB2
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      SPANXB2 gene at Home site.
    Version: 3.12.162 20 Aug 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4