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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SPAG5 Gene

protein-coding   GIFtS: 50
GCID: GC17M026904

Sperm Associated Antigen 5

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Sperm Associated Antigen 51 2     DEEPEST2
astrin1 2     hMAP1262
Mitotic Spindle Associated Protein P1261 2     Sperm-Associated Antigen 52
Mitotic Spindle Coiled-Coil Related Protein1 2     Astrin3
Mitotic Spindle-Associated Protein P1262 3     Deepest3
MAP1262 3     

External Ids:    HGNC: 134521   Entrez Gene: 106152   Ensembl: ENSG000000763827   UniProtKB: Q96R063   

Export aliases for SPAG5 gene to outside databases

Previous GC identifers: GC17M026749 GC17M028804 GC17M027050 GC17M023928 GC17M023113


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SPAG5 Gene:
This gene encodes a protein associated with the mitotic spindle apparatus. The encoded protein may be involved in
the functional and dynamic regulation of mitotic spindles. (provided by RefSeq, Jul 2008)

GeneCards Summary for SPAG5 Gene: 
SPAG5 (sperm associated antigen 5) is a protein-coding gene. Diseases associated with SPAG5 include patellar tendinitis, and estrogen-receptor positive breast cancer. GO annotations related to this gene include protein binding. An important paralog of this gene is ENSG00000258472.

UniProtKB/Swiss-Prot: SPAG5_HUMAN, Q96R06
Function: Essential component of the mitotic spindle required for normal chromosome segregation and progression
into anaphase. Required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance
of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore
attachments

Gene Wiki entry for SPAG5 (Sperm associated antigen 5) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.2  NT_010799.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SPAG5 gene promoter:
         RFX1   RP58   Tal-1   ATF-2   Nkx2-5   NF-E2 p45   E47   CP2   c-Jun   NF-E2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSPAG5 promoter sequence
   Search SABiosciences Chromatin IP Primers for SPAG5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SPAG5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q11.2   Ensembl cytogenetic band:  17q11.2   HGNC cytogenetic band: 17q11.2

SPAG5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SPAG5 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M026904:  view genomic region     (about GC identifiers)

Start:
26,904,583 bp from pter      End:
26,926,297 bp from pter
Size:
21,715 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SPAG5_HUMAN, Q96R06 (See protein sequence)
Recommended Name: Sperm-associated antigen 5  
Size: 1193 amino acids; 134422 Da
Subunit: Homodimer, with a globular head domain and a long stalk. Homooligomer; the globular head domains
associate, resulting in aster-like structures. Binds to microtubules in the mitotic spindle. Interacts with
DCLRE1B/Apollo. Part of an astrin (SPAG5)-kinastrin (SKAP) complex containing KNSTRN, SPAG5, PLK1, DYNLL1 and
SGOL2. Interacts with KNSTRN
Subcellular location: Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole.
Chromosome, centromere, kinetochore. Note=In a punctate pattern in interphase cells. During mitosis, detected at
spindle poles during prophase, throughout the spindle in metaphase and anaphase, and at midzone microtubules in
anaphase and telophase. Detected on kinetochores of chromosomes that have congressed. The astrin
(SPAG5)-kinastrin (SKAP) complex localizes to the microtubule plus ends (By similarity)
Sequence caution: Sequence=AAD02813.1; Type=Frameshift; Positions=1093; Sequence=AAL06396.2; Type=Frameshift;
Positions=1135;
Secondary accessions: O95213 Q9BWE8 Q9NT17 Q9UFE6

Explore the universe of human proteins at neXtProt for SPAG5: NX_Q96R06

Explore proteomics data for SPAG5 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96R06

  • SPAG5 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SPAG5 Protein Expression
    REFSEQ proteins: NP_006452.3  
    ENSEMBL proteins: 
     ENSP00000323300   ENSP00000466021   ENSP00000464400   ENSP00000462663   ENSP00000444223  

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    Gene Ontology (GO): 5/9 cellular component terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000776kinetochore IDA--
    GO:0000777condensed chromosome kinetochore IEA--
    GO:0000922spindle pole IEA--
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--

    SPAG5 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ProtoNet protein and cluster: Q96R06


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SPAG5_HUMAN, Q96R06
    Function: Essential component of the mitotic spindle required for normal chromosome segregation and progression
    into anaphase. Required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance
    of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore
    attachments

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI19197158
         
    SPAG5 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SPAG5:
     Upregulation of Wnt/beta-caten 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Spag5):
     normal 

    SPAG5 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Spag5tm1Vdh for SPAG5

       inGenious Targeting Laboratory - Custom generated mouse model solutions for SPAG5 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SPAG5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    5/19 Interacting proteins for SPAG5 (Q96R062, 3 ENSP000003233004) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CLASP1Q7Z4602, 3, ENSP000002637104MINT-8080001 MINT-8080014 MINT-8080057 I2D: score=1 STRING: ENSP00000263710
    SNAPINO952952, 3, ENSP000003576744MINT-63284 I2D: score=5 STRING: ENSP00000357674
    ATN1P542592, 3, ENSP000003490764MINT-2868607 I2D: score=3 STRING: ENSP00000349076
    ADAM15Q134443, ENSP000003494364I2D: score=2 STRING: ENSP00000349436
    MGEA5O605023, ENSP000003548504I2D: score=2 STRING: ENSP00000354850
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000070mitotic sister chromatid segregation IMP--
    GO:0000090mitotic anaphase ----
    GO:0007049cell cycle NAS15504738
    GO:0007051spindle organization NAS15504738
    GO:0007059chromosome segregation IMP--

    SPAG5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SPAG5

    Search CenterWatch for drugs/clinical trials and news about SPAG5

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SPAG5 gene: 
    NM_006461.3  

    Unigene Cluster for SPAG5:

    Sperm associated antigen 5
    Hs.514033  [show with all ESTs]
    Unigene Representative Sequence: AF345347
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000321765(uc002hbq.3) ENST00000378976 ENST00000580567 ENST00000578479
    ENST00000536674
    miRNA
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    Additional mRNA sequence: 

    AF063308.1 AF345347.2 AF399910.1 AK025725.1 AK292398.1 AK316079.1 AL122116.1 AL137585.1 
    BC000322.2 BC113055.1 

    13 DOTS entries:

    DT.91883599  DT.413103  DT.120931215  DT.91785667  DT.120931219  DT.97762931  DT.75102639  DT.95280592 
    DT.120931216  DT.120931376  DT.120931455  DT.91842439  DT.120931252 

    24/255 AceView cDNA sequences (see all 255):

    BU175001 BU145728 BU957307 CA309624 CA423523 BU182218 BQ773438 BE391536 
    BQ684154 BU177996 CA430548 BM680025 BM909103 AL043729 BU187086 AL043765 
    BQ214298 BX386712 BU686392 BU185331 BG328725 BQ641813 BE890813 BM741059 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for SPAG5 (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16a · 16b ^ 17a ·
    SP1:                          -                                                                                                                             -   
    SP2:                                                                                                                                                            
    SP3:                          -     -     -                             -                                                                                       
    SP4:                                                                                                                                                        -   
    SP5:                                                              -     -     -     -     -     -     -     -                                                   

    ExUns: 17b · 17c ^ 18 ^ 19 ^ 20a · 20b · 20c ^ 21 ^ 22 ^ 23 ^ 24 ^ 25
    SP1:                                                                        
    SP2:                                                                        
    SP3:                                                                        
    SP4:                                                                        
    SP5:                                                                        


    ECgene alternative splicing isoforms for SPAG5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SPAG5 expression in normal human tissues (normalized intensities)      SPAG5 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATCAAGTTCC
    SPAG5 Expression
    About this image


    SPAG5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/18 selected tissues (see all 18) fully expand
     
     Brain (Nervous System)    fully expand to see all 8 entries
             Choroid Plexus Progenitor Cells Choroid Plexus
             Thalamus
             brain/midbrain   
     
     Eye (Sensory Organs)    fully expand to see all 2 entries
             GABAergic Amacrine Cells Inner Nuclear Layer
             Retina
     
     Nose (Sensory Organs)    fully expand to see all 2 entries
             sensory organ/nose/nasal cavity   
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Telencephalon
     
     Limb (Muscoskeletal System)    fully expand to see all 2 entries
             limb/hindlimb   

    See SPAG5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SPAG5

    SOURCE GeneReport for Unigene cluster: Hs.514033

    UniProtKB/Swiss-Prot: SPAG5_HUMAN, Q96R06
    Tissue specificity: Highly expressed in testis. Detected at low levels in placenta, liver, pancreas, thymus and
    colon

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for SPAG5 gene from 3/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Spag51 , 5 sperm associated antigen 51, 5 77.96(n)1
    68.02(a)1
      11 (46.74 cM)5
    541411  NM_017407.21  NP_059103.11 
     783015295 
    chicken
    (Gallus gallus)
    Aves LOC7717021 sperm-associated antigen 5-like 48.59(n)
    36.96(a)
      771702  XM_001234949.2  XP_001234950.2 
    zebrafish
    (Danio rerio)
    Actinopterygii wu:fb54e101 wu:fb54e10 43.51(n)
    28.98(a)
      567619  XM_690920.4  XP_696012.3 


    ENSEMBL Gene Tree for SPAG5 (if available)
    TreeFam Gene Tree for SPAG5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SPAG5 gene
    ENSG000002584722  

    SPAG5 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/382 SNPs in SPAG5 are shown (see all 382)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2002594571,2
    C--26906126(+) CAGTTC/TTTCAT 1 -- int10--------
    rs1117231861,2
    C,F--26906207(+) GCTTCT/CTTTGC 2 /K syn13Minor allele frequency- C:0.00CSA NA 4555
    rs1857207641,2
    C--26906336(+) CATAAC/GAGGAT 1 -- int10--------
    rs1126101941,2
    C--26906344(+) GATGTC/TTCACT 1 -- int11Minor allele frequency- T:0.50CSA 2
    rs1484576361,2
    C--26906362(+) TGTCAC/GCAAAA 1 -- int10--------
    rs1425979151,2
    C--26906371(+) AACTGC/TATCCC 1 -- int10--------
    rs1906767051,2
    C--26906746(+) AGGCAA/GGATCC 1 -- int10--------
    rs1509632421,2
    C,F--26906790(+) AACCAT/CTGATG 2 /M /V mis11Minor allele frequency- C:0.01NA 4552
    rs2022211871,2
    --26907001(+) TTTCCC/TACCCC 1 -- int10--------
    rs1996884431,2
    C--26907110(+) AGGCTC/GTACTC 2 T R mis10--------

    HapMap Linkage Disequilibrium report for SPAG5 (26904583 - 26926297 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for SPAG5: --
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    4 diseases for SPAG5:    About MalaCards
    patellar tendinitis    estrogen-receptor positive breast cancer    oligohydramnios    breast cancer

    1 disease from the University of Copenhagen DISEASES database for SPAG5:
    Patellar tendinitis

    SPAG5 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SPAG5
    Human Genome Epidemiology (HuGE) Navigator: SPAG5 (1 document)

    Export disorders for SPAG5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SPAG5 gene, integrated from 9 sources (see all 41):
    (articles sorted by number of sources associating them with SPAG5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and characterization of hMAP126, a new member of mitotic spindle-associated proteins. (PubMed id 11549262)1, 2, 3 Chang M.-S.... Yang Y.-C. (2001)
    2. The mitotic-spindle-associated protein astrin is essential for progression through mitosis. (PubMed id 12356910)1, 2, 9 Gruber J.... Hatzfeld M. (2002)
    3. Analysis of mitotic microtubule-associated proteins using mass spectrometry identifies astrin, a spindle-associated protein. (PubMed id 11724960)1, 2, 9 Mack G.J. and Compton D.A. (2001)
    4. Centrosome-related genes, genetic variation, and risk of breast cancer. (PubMed id 20508983)1, 4 Olson J.E....Couch F.J. (2010)
    5. SNM1B/Apollo interacts with astrin and is required for the prophase cell cycle checkpoint. (PubMed id 19197158)1, 2 Liu L....Legerski R. (2009)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. hNinein is required for targeting spindle-associated protein Astrin to the centrosome during the S and G2 phases. (PubMed id 17383637)1, 9 Cheng T.S....Hong Y.R. (2007)
    8. Silencing of astrin induces the p53-dependent apoptosis by suppression of HPV18 E6 expression and sensitizes cells to paclitaxel treatment in HeLa cells. (PubMed id 16546135)1, 9 Yang Y.C....Chang M.S. (2006)
    9. Astrin regulates Aurora-A localization. (PubMed id 18361916)1, 9 Du J....Hannon G.J. (2008)
    10. Glycogen synthase kinase 3beta interacts with and phosphorylates the spindle-associated protein astrin. (PubMed id 18055457)1, 9 Cheng T.S....Hong Y.R. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10615 HGNC: 13452 AceView: SPAG5 Ensembl:ENSG00000076382 euGenes: HUgn10615
    ECgene: SPAG5 H-InvDB: SPAG5

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SPAG5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SPAG5 gene:
    Search GeneIP for patents involving SPAG5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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