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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SPA17 Gene

protein-coding   GIFtS: 50
GCID: GC11P124577

Sperm Autoantigenic Protein 17

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Sperm Autoantigenic Protein 171 2 3     SP172 3
Cancer/Testis Antigen 221 2 3     SP17-12
Sperm Protein 172 3     Sperm Surface Protein Sp172
CT222 3     Sp17-13

External Ids:    HGNC: 112101   Entrez Gene: 533402   Ensembl: ENSG000000641997   OMIM: 6086215   UniProtKB: Q155063   

Export aliases for SPA17 gene to outside databases

Previous GC identifers: GC11P126544 GC11P126057 GC11P124081 GC11P124048 GC11P120486


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SPA17 Gene:
This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human
cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ
calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions
in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the
zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion
functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome
10q22.(provided by RefSeq, Jan 2009)

GeneCards Summary for SPA17 Gene: 
SPA17 (sperm autoantigenic protein 17) is a protein-coding gene. Diseases associated with SPA17 include testicular cancer, and myeloma. GO annotations related to this gene include cAMP-dependent protein kinase regulator activity.

UniProtKB/Swiss-Prot: SP17_HUMAN, Q15506
Function: Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high
affinity. Might function in binding zona pellucida and carbohydrates (By similarity)

Gene Wiki entry for SPA17 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.2  NT_033899.8  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SPA17 gene promoter:
         NF-1   GCNF   IRF-1   HNF-4alpha2   NF-AT   Egr-4   HNF-4alpha1   c-Ets-1   GCNF-1   GCNF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSPA17 promoter sequence
   Search SABiosciences Chromatin IP Primers for SPA17

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SPA17


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q24.2   Ensembl cytogenetic band:  11q24.2   HGNC cytogenetic band: 11q24.2

SPA17 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SPA17 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P124577:  view genomic region     (about GC identifiers)

Start:
124,543,694 bp from pter      End:
124,567,414 bp from pter
Size:
23,721 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SP17_HUMAN, Q15506 (See protein sequence)
Recommended Name: Sperm surface protein Sp17  
Size: 151 amino acids; 17406 Da
Subunit: Homodimer (By similarity). May interact with ROPN1
Subcellular location: Membrane; Peripheral membrane protein (Potential)
Secondary accessions: B2R4F2 Q9BXF7

Explore the universe of human proteins at neXtProt for SPA17: NX_Q15506

Explore proteomics data for SPA17 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q15506

  • SPA17 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SPA17 Protein Expression
    REFSEQ proteins: NP_059121.1  
    ENSEMBL proteins: 
     ENSP00000227135   ENSP00000432305  

    Human Recombinant Protein Products for SPA17: 
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    Novus Biologicals SPA17 Proteins
    Novus Biologicals SPA17 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA18421703
    GO:0016020membrane IEA--
    GO:0031514motile cilium IDA18421703
    GO:0072372primary cilium IDA18421703

    SPA17 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR012105 Sp17
     IPR003117 cAMP_dep_PK_reg_su_I/II_a/b
     IPR000048 IQ_motif_EF-hand-BS

    Graphical View of Domain Structure for InterPro Entry Q15506

    ProtoNet protein and cluster: Q15506

    UniProtKB/Swiss-Prot: SP17_HUMAN, Q15506
    Similarity: Contains 1 IQ domain


    SPA17 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SP17_HUMAN, Q15506
    Function: Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high
    affinity. Might function in binding zona pellucida and carbohydrates (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0008603cAMP-dependent protein kinase regulator activity IEA--
         
    SPA17 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SPA17:
     Decreased telomerase activity 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SPA17 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SPA17

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SPA17 
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    miRNA
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    6 QIAGEN miScript miRNA Assays for microRNAs that regulate SPA17:
    hsa-miR-513b hsa-miR-7-1* hsa-miR-7-2* hsa-miR-3134 hsa-miR-664 hsa-miR-105
    SwitchGear 3'UTR luciferase reporter plasmidSPA17 3' UTR sequence
    Inhib. RNA
    Products:
        
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SPA17

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for SPA17 (Q155063 ENSP000002271354) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AKAP3O759693, ENSP000002288504I2D: score=3 STRING: ENSP00000228850
    ROPN1Q9HAT03, ENSP000001841834I2D: score=2 STRING: ENSP00000184183
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001539ciliary or bacterial-type flagellar motility IDA18421703
    GO:0007165signal transduction IEA--
    GO:0007283spermatogenesis TAS8688458
    GO:0007338single fertilization TAS8688458
    GO:0007339binding of sperm to zona pellucida IEA--

    SPA17 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SPA17 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SPA17 (SP17)

    1 Novoseek inferred chemical compound relationship for SPA17 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    sp(1-7) 99.5 327 14712480 (13), 7578682 (11), 15257753 (10), 12015770 (9) (see all 42)

    Search CenterWatch for drugs/clinical trials and news about SPA17 / SP17

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SPA17 gene: 
    NM_017425.3  

    Unigene Cluster for SPA17:

    Sperm autoantigenic protein 17
    Hs.286233  [show with all ESTs]
    Unigene Representative Sequence: AL527801
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000227135 ENST00000532692(uc001qap.3) ENST00000529498 ENST00000524614

    miRNA
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    6 QIAGEN miScript miRNA Assays for microRNAs that regulate SPA17:
    hsa-miR-513b hsa-miR-7-1* hsa-miR-7-2* hsa-miR-3134 hsa-miR-664 hsa-miR-105
    SwitchGear 3'UTR luciferase reporter plasmidSPA17 3' UTR sequence
    Inhib. RNA
    Products:
         
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SPA17
    Sirion Biotech Customized lentivirus for stable overexpression of SPA17 
                         Customized lentivirus expression plasmids for stable overexpression of SPA17 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SPA17
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SPA17

    Additional mRNA sequence: 

    AF334735.1 AK307271.1 AK311806.1 BC019224.1 BC032457.2 

    4 DOTS entries:

    DT.95265897  DT.100881343  DT.75155024  DT.91918951 

    24/82 AceView cDNA sequences (see all 82):

    BI825620 BC032457 AW139711 AW439848 AL522318 AL522317 BE348235 BM762370 
    CR602938 BU844909 AL527802 AA382958 AA122324 BU729714 CR625142 BX097241 
    BC019224 AA620983 BM704178 AW204599 AA122286 BP369357 AA369666 AI140547 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SPA17 expression in normal human tissues (normalized intensities)      SPA17 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGTTTGTTTA
    SPA17 Expression
    About this image


    SPA17 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/7 selected tissues (see all 7) fully expand
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             XY Germ Cells Testis Cord
             Testis Interstitium
     
     Epithelium (Respiratory System)    fully expand to see all 4 entries
             bronchial epithelia   
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Choroid Plexus
             brain/forebrain/telencephalon   
     
     Pancreas (Endocrine System)
             Posterior foregut-like cells ( A scalable, suspension protocol for derivation of...
     
     Nose (Sensory Organs)
             nasal epithelium   

    See SPA17 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SPA17

    SOURCE GeneReport for Unigene cluster: Hs.286233

    UniProtKB/Swiss-Prot: SP17_HUMAN, Q15506
    Tissue specificity: Testis and sperm specific

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SPA17

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for SPA17 gene from 3/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Spa171 , 5 sperm autoantigenic protein 171, 5 81.51(n)1
    73.29(a)1
      9 (20.78 cM)5
    206861  NM_011449.21  NP_035579.11 
     376032955 
    lizard
    (Anolis carolinensis)
    Reptilia SPA176
    Sperm surface protein Sp17
    48(a)
    1 ↔ 1
    GL343322.1(151436-158084)
    zebrafish
    (Danio rerio)
    Actinopterygii SPA176
    sperm autoantigenic protein 17
    10(a)
    1 ↔ 1
    15(21229119-21249295)


    ENSEMBL Gene Tree for SPA17 (if available)
    TreeFam Gene Tree for SPA17 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SPA17 gene

    SPA17 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SPA17
    PGOHUM00000238544


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/263 SNPs in SPA17 are shown (see all 263)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1169934371,2
    F--124548376(+) TATGCT/CATCAT 1 -- int11Minor allele frequency- C:0.02NA 120
    rs723510811,2
    C--124548413(+) TGTGT-/TG/TG 
    TGTGTGTG
    GTGTG
    1 -- int10--------
    rs1847978971,2
    C--124548414(+) TAACTC/GTGTGT 1 -- int10--------
    rs1388050161,2
    --124548512(+) GTGTAA/CTCGTG 1 -- int10--------
    rs1892131451,2
    --124548591(+) GGCATA/GCACAA 1 -- int10--------
    rs1117574851,2
    F--124548653(+) GAGACG/AGGGTT 1 -- int11Minor allele frequency- A:0.50CSA 2
    rs1458957681,2
    --124548716(+) CCTCCA/GCCTCC 1 -- int10--------
    rs800356721,2
    C--124548760(+) GCCCAA/GCTTTG 1 -- int10--------
    rs766267991,2
    F--124549082(+) ACATAT/AGAGCC 1 -- int11Minor allele frequency- A:0.01NA 120
    rs1815932791,2
    --124549105(+) ACTGCA/GTGACA 1 -- int10--------

    HapMap Linkage Disequilibrium report for SPA17 (124543694 - 124567414 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for SPA17: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SPA17
    DNA2.0 Custom Variant and Variant Library Synthesis for SPA17

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 608621    OMIM disorders: --

    16 diseases for SPA17:    About MalaCards
    testicular cancer    myeloma    clear cell adenocarcinoma    multiple myeloma
    graft versus host disease    oral squamous cell carcinoma    esophageal cancer    ovarian cancer
    infertility    cervical cancer    esophagitis    squamous cell carcinoma
    cervicitis    rheumatoid arthritis    arthritis    adenocarcinoma

    1 disease from the University of Copenhagen DISEASES database for SPA17:
    Multiple myeloma

    SPA17 for disorders           About GeneDecksing

    9 Novoseek inferred disease relationships for SPA17 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    testicular cancer 58 4 18779750 (1), 20485677 (1), 17336323 (1), 12213290 (1)
    ovarian cancer 53.3 13 19102497 (4), 14712480 (2), 19900363 (1), 18779750 (1) (see all 7)
    ovarian carcinoma 48.1 4 12015770 (4)
    myeloma 46.3 1 11222401 (1)
    tumors 24.5 37 14712480 (9), 12015770 (3), 15148930 (2), 17336323 (2) (see all 15)
    graft-versus-host disease 24 2 11477539 (1)
    carcinoma squamous cell 8 4 19685492 (1), 17230514 (1)
    cancer 1.09 5 12213290 (2), 16138340 (1), 16438728 (1)
    metastasis 0 1 16311122 (1)

    Genetic Association Database (GAD): SPA17
    Human Genome Epidemiology (HuGE) Navigator: SPA17 (1 document)

    Export disorders for SPA17 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SPA17 gene, integrated from 9 sources (see all 62):
    (articles sorted by number of sources associating them with SPA17)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and sequencing of cDNAs encoding the human sperm protein, Sp17. (PubMed id 8688458)1, 2, 3, 9 Lea I.A.... O'Rand M.G. (1996)
    2. Genomic organization of an intron-containing sperm protein 17 gene (Sp17-1) and an intronless pseudogene (Sp17-2) in humans: a new model. (PubMed id 12393185)1, 2, 9 Buchli R.... Robbins D.L. (2002)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Expression of sperm protein 17 (Sp17) in ovarian cancer. (PubMed id 14712480)1, 9 Straughn J.M....Strong T.V. (2004)
    5. Sequence and localization of the mouse sperm autoantigenic protein, Sp17. (PubMed id 7578682)1, 9 Kong M....O'Rand M.G. (1995)
    6. Association of sperm protein 17 with A-kinase anchoring protein 3 in flagella. (PubMed id 15257753)1, 9 Lea I.A....O'Rand M.G. (2004)
    7. Characterization of sperm protein 17 in human somatic and neoplastic tissue. (PubMed id 12213290)1, 9 De Jong A....Robbins D. (2002)
    8. Sperm protein 17 is a novel marker for predicting cis platin response in esophageal squamous cancer cell lines. (PubMed id 19685492)1, 9 Kausar T....Ralhan R. (2010)
    9. Clinical significance of sperm protein 17 expression and immunogenicity in esophageal cancer. (PubMed id 17230514)1, 9 Gupta G....Ralhan R. (2007)
    10. Sperm protein 17 is expressed in the sperm fibrous sh eath. (PubMed id 19604394)1, 9 Chiriva-Internati M....Kast W.M. (2009)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 53340 HGNC: 11210 AceView: SPA17 Ensembl:ENSG00000064199 euGenes: HUgn53340
    ECgene: SPA17 H-InvDB: SPA17

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
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    About This Section
    NameDescription
    PharmGKB entry for SPA17 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for SPA17 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
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    Patent Information for SPA17 gene:
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