Aliases for SP140 Gene
External Ids for SP140 Gene
GeneCards Summary for SP140 Gene
SP140 (SP140 Nuclear Body Protein) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is SP140L.
UniProtKB/Swiss-Prot for SP140 Gene
Component of the nuclear body, also known as nuclear domain 10, PML oncogenic domain, and KR body (PubMed:8910577). May be involved in the pathogenesis of acute promyelocytic leukemia and viral infection (PubMed:8910577). May play a role in chromatin-mediated regulation of gene expression although it does not bind to histone H3 tails (PubMed:24267382).