SP110 Gene
protein-coding GIFtS: 57
GCID: GC02M230997
|
|
SP110 nuclear body protein(Previous names: interferon-induced protein 41, 30kD )
(Previous symbols: IFI41, IFI75)
| |
Aliases
for SP110 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| SP110 Nuclear Body Protein1 2 | | Transcriptional Coactivator Sp1102 3 | | IFI411 2 5 | | VODI2 5 | | IFI751 2 5 | | IPR12 | | Interferon-Induced Protein 41, 30kD1 2 | | Interferon-Induced Protein 75, 52kD2 | | Interferon-Induced Protein 41/752 3 | | Phosphoprotein 412 | | Speckled 110 KDa2 3 | | Phosphoprotein 752 |
Export aliases for SP110 gene to outside databasesPrevious GC identifers: GC02M229093 GC02M229765 GC02M231236 GC02M230859 GC02M230741 GC02M222874 |
Summaries
for SP110 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SP110:
The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is amember of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. Theprotein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. Inaddition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction ofmyeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants,encoding distinct isoforms, have been identified. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: SP110_HUMAN, Q9HB58Function: Transcription factor. May be a nuclear hormone receptor coactivator. Enhances transcription of genes withretinoic acid response elements (RARE)
Gene Wiki entry for SP110
|
Genomic Views
for SP110 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_005403.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SP110 gene promoter:
Nkx2-5 STAT5A
Other transcription factors
Search SABiosciences Chromatin IP Primers for SP110
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SP110 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q37.1 Ensembl cytogenetic band: 2q37.1 HGNC cytogenetic band: 2q37.1SP110 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M230997: view genomic region
(about GC identifiers)
Start:
|
231,032,009 bp from pter |
End:
|
231,090,444 bp from pter |
Size:
|
58,436 bases |
Orientation:
|
minus strand |
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Proteins
for SP110 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SP110_HUMAN, Q9HB58 (See
protein sequence)Recommended Name: Sp110 nuclear body protein Size: 689 amino acids; 78396 Da
Subunit: Isoform 3 interacts with HCV core protein
Subcellular location: Nucleus. Note=Found in the nuclear body
Sequence caution: Sequence=AAF99318.1; Type=Frameshift; Positions=Several; Sequence=AAG09826.1; Type=Frameshift;Positions=141, 143; Sequence=AK026488; Type=Frameshift; Positions=296, 542, 567;
Secondary accessions: B4DVI4 F5H1M1 Q14976 Q14977 Q53TG2 Q8WUZ6 Q9HCT8Alternative splicing: 7 isoforms: Q9HB58-1 Q9HB58-2 Q9HB58-3 Q9HB58-4 Q9HB58-5 Q9HB58-6 Q9HB58-7 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SP110: NX_Q9HB58
Post-translational modifications:
Phosphorylated (isoform 2)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9HB58
SP110 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001171944.1 NP_004500.3 NP_004501.3 NP_536349.2
ENSEMBL proteins: ENSP00000258381 ENSP00000351488 ENSP00000375902 ENSP00000258382 ENSP00000387172 ENSP00000393992 ENSP00000399978 ENSP00000439558 ENSP00000344049
Human Recombinant Protein Products for SP110:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
SP110 for ontologies About GeneDecksing
SP110 Antibody Products:
Assay Products for SP110: |
Protein
Domains /
Families
for SP110 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SP110 for domains About GeneDecksing
5/8 InterPro domains/families (see all 8):Graphical View of Domain Structure for InterPro Entry Q9HB58ProtoNet protein and cluster: Q9HB58 4 Blocks protein families: IPB000770 SAND domain IPB001965 Zn-finger-like IPB004865 Sp100 domain IPB010919 SAND-like
UniProtKB/Swiss-Prot: SP110_HUMAN, Q9HB58Similarity: Contains 1 bromo domainSimilarity: Contains 1 HSR domainSimilarity: Contains 1 PHD-type zinc fingerSimilarity: Contains 1 SAND domain |
Function
for SP110 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: SP110_HUMAN, Q9HB58Function: Transcription factor. May be a nuclear hormone receptor coactivator. Enhances transcription of genes withretinoic acid response elements (RARE)Induction: By IFNG/IFN-gamma and all-trans retinoic acid (ATRA) Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
SP110 for ontologies About GeneDecksing
Phenotypes:
2 GenomeRNAi human phenotypes for SP110:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SP110 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SP110 (see all 5)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 4): SP110 (NM_080424) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SP110 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SP110 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SP110 |
|
Pathways & Interactions
for SP110 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SP110
STRING Interaction
Network Preview (showing 5 interactants - click image to see more details)
5/13 Interacting proteins for SP110 (Q9HB582, 3 ENSP000002583814) via UniProtKB, MINT, STRING, and/or I2D (see all 13)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
SP110 for ontologies About GeneDecksing
|
Drugs & Compounds
for SP110 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SP110
Search CenterWatch for drugs/clinical trials and news about SP110
|
Transcripts
for SP110 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SP110 gene (4 alternative transcripts): NM_001185015.1 NM_004509.3 NM_004510.3 NM_080424.2 Unigene Cluster for SP110: SP110 nuclear body protein Hs.145150 [show with all ESTs]Unigene Representative Sequence: AK12827417 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000477068 ENST00000480916 ENST00000258381(uc002vqg.3 uc002vqh.3)
ENST00000483067 ENST00000358662 ENST00000463022 ENST00000392048(uc010fxj.3)
ENST00000258382(uc002vqi.4 uc010fxk.3) ENST00000489597 ENST00000490880
ENST00000486146 ENST00000409815 ENST00000455674 ENST00000462232 ENST00000416610
ENST00000540870(uc021vxx.1) ENST00000338556
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SP110 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SP110 (see all 5)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): SP110 (NM_080424) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SP110 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SP110 |
Additional cDNA sequence: AF280094.1 AF280095.1 AK026488.1 AK128274.1 AK301097.1 AL832300.1 BC012447.2 BC019059.2 L22343.1 18 DOTS entries: DT.97844819 DT.100784503 DT.315250 DT.100784505 DT.87016829 DT.315249 DT.120949401 DT.97787522 DT.120949492 DT.92423845 DT.120949304 DT.87008738 DT.91704797 DT.100704880 DT.120949368 DT.120949382 DT.121015844 DT.40295425 24/174 AceView cDNA sequences (see all 174): AW204185 AA926890 AA831048 AA907317 AA443705 AI077443 AI540791 AA780399 AL557996 CR625933 AA252779 BU174698 AA744811 CB529938 AA074714 AI807423 AW469400 AW137571 AI168372 AA504832 BF223153 CB963887 BQ889855 BC019059
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for SP110 (see all 7) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16a | · | 16b | ^ | 17 | ^ | 18 | ^ | 19a | · | 19b | ^ | 20a | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | - | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | - | | - | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 20b |
|---|
|
| SP1: | | | |
| SP2: | | | |
| SP3: | | | |
| SP4: | | | |
| SP5: | | |
ECgene alternative splicing isoforms for SP110
|
Expression
for SP110 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SP110 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See SP110 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SP110
SOURCE GeneReport for Unigene cluster: Hs.145150
UniProtKB/Swiss-Prot: SP110_HUMAN, Q9HB58Tissue specificity: Highly expressed in peripheral blood leukocytes and spleen. Detected at intermediate levels inthymus, prostate, testis, ovary, small intestine and colon, and at low levels in heart, brain, placenta, lung, liver,skeletal muscle, kidney and pancreas
SABiosciences Expression via Pathway-Focused PCR Array including SP110: | Interferons & Receptors in human mouse rat |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SP110
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SP110 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SP110 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SP110 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SP110 |
Orthologs
for SP110 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for SP110 gene from 1/6 species (see all 6) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
zebrafish
(Danio rerio) |
Actinopterygii |
BX569789.26BX569789.56 |
-- |
34(a)21(a) |
many ↔ manymany ↔ many |
3(24837780-24845598) 3(24862707-24880269) |
ENSEMBL Gene Tree for SP110 (if available)
TreeFam Gene Tree for SP110 (if available) |
Paralogs
for SP110 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SP110 gene
- SP1002 SP140L2 SP1402
10 SIMAP similar genes for SP110 using alignment to 12 protein entries: SP110_HUMAN (see all proteins):TRIM66 CHD4 CHD5 TRIM33 SP140L AIRE
SP100 SP140 DKFZp686E07254 FLJ00340
SP110 for paralogs About GeneDecksing
|
Genomic Variants
for SP110 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SP110 (231032009 - 231090444 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for SP110
1 CNV: 63325
Human Gene Mutation Database (HGMD): SP110
Locus Specific Mutation Databases (LSDB): SP110
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SP110 |
|
Disorders
/ Diseases
for SP110 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SP110 for disorders About GeneDecksing
OMIM gene information: 604457
OMIM disorders: 235550 607948
UniProtKB/Swiss-Prot: SP110_HUMAN, Q9HB58
Defects in SP110 are the cause of hepatic venoocclusive disease with immunodeficiency (VODI) [MIM:235550].VODI is an autosomal recessive primary immunodeficiency associated with hepatic vascular occlusion and fibrosis. Theimmunodeficiency is characterized by severe hypogammaglobulinemia, combined T and B cell immunodeficiency, absentlymph node germinal centers, and absent tissue plasma cells
13  diseases for SP110: About MalaCardslymph node tuberculosis hepatic veno-occlusive disease with immunodeficiency mycobacterium tuberculosis extrapulmonary tuberculosis
chronic lymphocytic leukemia lymphocytic leukemia tuberculosis pulmonary tuberculosis
hepatitis c immunodeficiency hepatitis leukemia
prostatitis
1 disease from the University of Copenhagen DISEASES database for SP110:Tuberculosis GeneTests: SP110
Hepatic Veno-occlusive Disease with Immunodeficiency
Genetic Association Database (GAD): SP110
Human Genome Epidemiology (HuGE) Navigator: SP110 (28 documents)
Export disorders for SP110 gene to outside databases
|
Publications
for SP110 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SP110 gene, integrated from 9 sources (see all 44):
(articles sorted by number of sources associating them with SP110) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning of two new interferon-induced, highly related nuclear phosphoproteins. (PubMed id 7693701)1, 2, 3 Kadereit S.... Meurs E.F. (1993)
- Sp110 localizes to the PML-Sp100 nuclear body and may function as a nuclear hormone receptor transcriptional coactivator. (PubMed id 10913195)1, 2, 9 Bloch D.B.... Bloch K.D. (2000)
- Variants in the SP110 gene are associated with genetic susceptibility to tuberculosis in West Africa. (PubMed id 16803959)1, 2 Tosh K.... Hill A.V.S. (2006)
- No associations of human pulmonary tuberculosis with Sp110 variants. (PubMed id 16816019)1, 2 Thye T....Meyer C.G. (2006)
- Mutations in the gene encoding the PML nuclear body protein Sp110 are associated with immunodeficiency and hepatic veno-occlusive disease. (PubMed id 16648851)1, 2 Roscioli T.... Buckley M.F. (2006)
- Genetic variations in humans associated with differences in the course of hepatitis C. (PubMed id 15063762)1, 4 Saito T....Kawata S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Modulation of retinoid signaling by a cytoplasmic viral protein via sequestration of Sp110b, a potent transcriptional corepressor of retinoic acid receptor, from the nucleus. (PubMed id 14559998)1, 2 Watashi K....Shimotohno K. (2003)
- Colocalization within the nucleolus of two highly related IFN-induced human nuclear phosphoproteins with nucleolin. (PubMed id 10388521)1, 3 Welsh G.I....Meurs E.F. (1999)
- Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia. (PubMed id 22700719)1 Slager S.L....Houlston R.S. (2012)
|
External Searches for SP110 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SP110 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SP110 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SP110 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SP110 | Pharmacogenomics, SNPs, Pathways | | SP110base | http://bioinf.uta.fi/SP110base/ | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/SP110 |
|
| | |
About This Section
| Patent Information for SP110 gene:
Search GeneIP for patents involving SP110
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SP110 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for SP110 | | OriGene shRNA RFP for SP110 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SP110 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SP110 | | | OriGene Protein Over-expression Lysate for SP110 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SP110 | | OriGene 3'-UTR Clone for SP110 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SP110 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SP110 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SP110 | | OriGene Custom Protein Services for SP110 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SP110 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SP110 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SP110 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SP110 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SP110 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SP110 |
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| | | | Search Tocris compounds for SP110 |
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 | | | SP110 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SP110 |
|  |  |  |  | | | | ThermoFisher Antibodies for SP110 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SP110 |
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