External Ids for SOX30 Gene
Previous GeneCards Identifiers for SOX30 Gene
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein acts as a transcriptional regulator when present in a complex with other proteins. It can activate p53 transcription to promote tumor cell apoptosis in lung cancer. The protein may be involved in the differentiation of developing male germ cells. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Apr 2015]
GeneCards Summary for SOX30 Gene
SOX30 (SRY-Box 30) is a Protein Coding gene. Among its related pathways are ERK Signaling. GO annotations related to this gene include sequence-specific DNA binding and RNA polymerase II transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is MIR6073.
UniProtKB/Swiss-Prot for SOX30 Gene
Transcriptional activator. Binds to the DNA sequence 5-ACAAT-3 and shows a preference for guanine residues surrounding this core motif.