Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



SOX30 Gene

protein-coding   GIFtS: 50
GCID: GC05M157053

SRY (Sex Determining Region Y)-Box 30

  Search for SOX30
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
SRY (Sex Determining Region Y)-Box 301 2
Sox30 Protein Type II2
Transcription Factor SOX-302

External Ids:    HGNC: 306351   Entrez Gene: 110632   Ensembl: ENSG000000396007   OMIM: 6066985   UniProtKB: O949933   

Export aliases for SOX30 gene to outside databases

Previous GC identifers: GC05M157102 GC05M157603 GC05M156988 GC05M157033 GC05M156985 GC05M152141


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for SOX30 Gene:
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the
regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a
transcriptional regulator after forming a protein complex with other proteins. The protein may be involved in the
differentiation of developing male germ cells. Alternative splicing results in multiple transcript variants.
(provided by RefSeq, Jul 2013)

GeneCards Summary for SOX30 Gene:
SOX30 (SRY (sex determining region Y)-box 30) is a protein-coding gene. GO annotations related to this gene include sequence-specific DNA binding RNA polymerase II transcription factor activity and sequence-specific DNA binding.

UniProtKB/Swiss-Prot: SOX30_HUMAN, O94993
Function: Transcriptional activator. Binds to the DNA sequence 5'-ACAAT-3' and shows a preference for guanine
residues surrounding this core motif




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
Regulatory elements:
   Regulatory transcription factor binding sites in the SOX30 gene promoter:
         PPAR-alpha   AREB6   IRF-2   AML1a   Pax-6   STAT3   GATA-1   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSOX30 promoter sequence
   Search Chromatin IP Primers for SOX30

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SOX30


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q33   Ensembl cytogenetic band:  5q33.3   HGNC cytogenetic band: 5q33

SOX30 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SOX30 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M157053:  view genomic region     (about GC identifiers)

Start:
157,052,687 bp from pter      End:
157,098,488 bp from pter
Size:
45,802 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: SOX30_HUMAN, O94993 (See protein sequence)
Recommended Name: Transcription factor SOX-30  
Size: 753 amino acids; 81854 Da
Secondary accessions: O94995 Q8IYX6
Alternative splicing: 2 isoforms:  O94993-1   O94993-2   

Explore the universe of human proteins at neXtProt for SOX30: NX_O94993

Explore proteomics data for SOX30 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SOX30 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_008948.1  NP_848511.1  

    ENSEMBL proteins: 
     ENSP00000309343   ENSP00000265007   ENSP00000427984  

    SOX30 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for SOX30
    OriGene Custom MassSpec
    OriGene Custom Protein Services for SOX30
    GenScript Custom Purified and Recombinant Proteins Services for SOX30
    Novus Biologicals SOX30 Proteins
    Novus Biologicals SOX30 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SOX30

     
    Search eBioscience for Proteins for SOX30 

    SOX30 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for SOX30
    Novus Biologicals SOX30 Antibodies
    Abcam antibodies for SOX30
    Cloud-Clone Corp. Antibodies for SOX30
    ThermoFisher Antibodies for SOX30
    LSBio Antibodies in human, mouse, rat for SOX30

    SOX30 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for SOX30
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SOX30
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SOX30
    Cloud-Clone Corp. CLIAs for SOX30
    Search eBioscience for ELISAs for SOX30 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    SOX: SRY (sex determining region Y)-boxes

    1 InterPro protein domain:
     IPR009071 HMG_box_dom

    Graphical View of Domain Structure for InterPro Entry O94993

    ProtoNet protein and cluster: O94993

    UniProtKB/Swiss-Prot: SOX30_HUMAN, O94993
    Similarity: Contains 1 HMG box DNA-binding domain


    Find genes that share domains with SOX30           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SOX30_HUMAN, O94993
    Function: Transcriptional activator. Binds to the DNA sequence 5'-ACAAT-3' and shows a preference for guanine
    residues surrounding this core motif

         Genatlas biochemistry entry for SOX30:
    SRY related HMG box gene 30,expressed in testis,potentially involved in differentiation of male germ cells with
    two alternatively spliced isoforms,modulator of LINE retroposons promoter activity

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000981NOT sequence-specific DNA binding RNA polymerase II transcription factor activity IDA10359848
    GO:0043565sequence-specific DNA binding IDA10359848
         
    Find genes that share ontologies with SOX30           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SOX30
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SOX30

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SOX30
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SOX30

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat SOX30 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate SOX30:
    hsa-miR-33a* hsa-miR-3658 hsa-miR-32*
    SwitchGear 3'UTR luciferase reporter plasmidSOX30 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SOX30
    Predesigned siRNA for gene silencing in human, mouse, rat SOX30

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SOX30

    Clone
    Products:
         
    OriGene clones in human, mouse for SOX30 (see all 11)
    OriGene ORF clones in mouse, rat for SOX30
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): SOX30 (NM_178424)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SOX30
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SOX30

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SOX30
    Browse ESI BIO Cell Lines and PureStem Progenitors for SOX30 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SOX30


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    SOX30_HUMAN, O94993: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2
    golgi apparatus1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    Find genes that share ontologies with SOX30           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for SOX30 About    
    See pathways by source

    SuperPathContained pathways About
    1ERK Signaling
    Molecular Mechanisms of Cancer0.51

    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for SOX30
        Molecular Mechanisms of Cancer


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SOX30
    Interactions:

        Search GeneGlobe Interaction Network for SOX30

    STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

    Selected Interacting proteins for SOX30 (O949932, 3 ENSP000002650074) via UniProtKB, MINT, STRING, and/or I2D (see all 21)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NUDT3O959892, 3MINT-68239 I2D: score=5 
    BAMBIQ131452, 3, ENSP000003646834MINT-66314 I2D: score=5 STRING: ENSP00000364683
    TRAF2Q129333, ENSP000002476684I2D: score=5 STRING: ENSP00000247668
    C6orf165Q8IYR03I2D: score=1 
    GKAP1Q5VSY03I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--
    GO:0006357NOT regulation of transcription from RNA polymerase II promoter IDA10359848
    GO:0006366transcription from RNA polymerase II promoter IDA10359848
    GO:0007283spermatogenesis IEA--

    Find genes that share ontologies with SOX30           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SOX30



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for SOX30 gene (2 alternative transcripts): 
    NM_007017.2  NM_178424.1  

    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000311371 ENST00000265007(uc003lxb.1 uc003lxc.1 uc011dds.1)
    ENST00000519442
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SOX30 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate SOX30:
    hsa-miR-33a* hsa-miR-3658 hsa-miR-32*
    SwitchGear 3'UTR luciferase reporter plasmidSOX30 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SOX30
    Predesigned siRNA for gene silencing in human, mouse, rat SOX30
    Clone
    Products:
         
    OriGene clones in human, mouse for SOX30 (see all 11)
    OriGene ORF clones in mouse, rat for SOX30
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): SOX30 (NM_178424)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SOX30
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SOX30
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for SOX30
    OriGene qSTAR qPCR primer pairs in human, mouse for SOX30
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SOX30
      QuantiTect SYBR Green Assays in human, mouse, rat SOX30
      QuantiFast Probe-based Assays in human, mouse, rat SOX30

    Selected AceView cDNA sequences (see all 33):

    BC035142 AI138249 NM_007017 BC033492 NM_178424 BX100955 AA983409 BI830793 
    AK055284 AI651883 AA994615 BI827150 BI826497 CB044023 AI917320 AI191937 
    AB022083 CD243909 AI797722 BI829275 AB022441 BP370744 AI223411 BI551315 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for SOX30    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b
    SP1:                                          
    SP2:                          -               


    ECgene alternative splicing isoforms for SOX30

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    SOX30 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAAAATACTG
    SOX30 Expression
    About this image


    SOX30 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Smooth Muscle (Muscoskeletal System)
             Juxtaglomerular Cells Afferent Arteriole
     
     Kidney (Urinary System)
             Juxtaglomerular Cells Afferent Arteriole
     
     Testis (Reproductive System)
    SOX30 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SOX30 Protein Expression

    UniProtKB/Swiss-Prot: SOX30_HUMAN, O94993
    Tissue specificity: Expressed in testis

        Custom PCR Arrays for SOX30
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for SOX30
    OriGene qSTAR qPCR primer pairs in human, mouse for SOX30
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SOX30
    QuantiTect SYBR Green Assays in human, mouse, rat SOX30
    QuantiFast Probe-based Assays in human, mouse, rat SOX30
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SOX30

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for SOX30 gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sox301 , 5 SRY-box containing gene 305
    SRY (sex determining region Y)-box 301
    83.15(n)1
    78.49(a)1
      11 (27.49 cM)5
    2141051  NM_173384.21  NP_775560.11 
     459803105 
    chicken
    (Gallus gallus)
    Aves SOX301 SRY (sex determining region Y)-box 30 64.81(n)
    55.73(a)
      416243  XM_414564.4  XP_414564.1 
    lizard
    (Anolis carolinensis)
    Reptilia SOX306
    SRY (sex determining region Y)-box 30
    61(a)
    1 ↔ 1
    GL343205.1(2820323-2837584)


    ENSEMBL Gene Tree for SOX30 (if available)
    TreeFam Gene Tree for SOX30 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for SOX30 gene
    10 SIMAP similar genes for SOX30 using alignment to 2 protein entries:     SOX30_HUMAN (see all proteins):
    SOX26    SOX27    SOX28    SOX25    soxB    SOX11
    SOX17    DKFZp586H0919    SOX15    SRY

    Find genes that share paralogs with SOX30           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for SOX30
    PGOHUM00000235436


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for SOX30 (see all 634)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1847977101,2
    --157052190(+) TGAGGA/GAAAAG 2 -- ds50010--------
    rs100578581,2
    C,H--157052225(+) ATCATC/TAATTC 2 -- ds50014Minor allele frequency- T:0.00NS EA 418
    rs176611911,2
    C,F,H--157052559(+) GCTAAT/CAGAAT 2 -- ds500118Minor allele frequency- C:0.05NA NS EA 2128
    rs1439897081,2
    --157052580(+) CTGGAC/GACTAT 2 -- ds50010--------
    rs170547731,2
    C,F,H--157052726(+) AGAACG/AATGTA 2 -- ut31 ese320Minor allele frequency- A:0.09NA NS EA WA 2446
    rs1889240301,2
    --157052780(+) GAAACA/CGAAAT 2 -- ut310--------
    rs1465150231,2
    --157052850(+) TGGTTA/GTTAGT 2 -- ut310--------
    rs2019294101,2
    C--157052924(+) TACATA/CAAAAA 2 -- ut310--------
    rs1922591541,2
    --157052941(+) ACATCC/TATAAG 2 -- ut310--------
    rs1847201081,2
    --157053103(+) ACATGC/TTGATG 2 -- ut310--------

    HapMap Linkage Disequilibrium report for SOX30 (157052687 - 157098488 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for SOX30:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv1868e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SOX30
    DNA2.0 Custom Variant and Variant Library Synthesis for SOX30

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 606698    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for SOX30:
    Ocular hypertension

    Find genes that share disorders with SOX30           About GenesLikeMe

    Genetic Association Database (GAD): SOX30

    Export disorders for SOX30 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for SOX30 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with SOX30)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of a novel Sry-related gene and its germ cell-specific expression. (PubMed id 10359848)1, 2, 9 Osaki E.... Semba K. (Nucleic Acids Res. 1999)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Origin and diversity of the SOX transcription factor gene family: genome-wide analysis in Fugu rubripes. (PubMed id 15019997)1, 3 Koopman P....Venkatesh B. (Gene 2004)
    4. HMG-box sequences from microbats homologous to the human SOX30 HMG-box. (PubMed id 11678506)1, 3 Bullejos M....SA!nchez A. (Genetica 2000)
    5. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (Sci Signal 2012)
    6. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    7. Characterization, phylogeny, alternative splicing and expression of Sox30 gene. (PubMed id 21143990)1 Han F....Wang D. (BMC Mol. Biol. 2010)
    8. Gene expression profiles of human trabecular meshwork cells induced by triamcinolone and dexamethasone. (PubMed id 18436822)1 Fan B.J....Pang C.P. (amp 2008)
    9. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    10. Framingham Heart Study genome-wide association: results for pulmonary function measures. (PubMed id 17903307)4 Wilk J.B....O'Connor G.T. (BMC Med. Genet. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 11063 HGNC: 30635 AceView: SOX30 Ensembl:ENSG00000039600 euGenes: HUgn11063
    ECgene: SOX30 H-InvDB: SOX30

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for SOX30 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for SOX30 gene:
    Search GeneIP for patents involving SOX30

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for SOX30  
     OriGene qPCR primer pairs and template standards for SOX30   OriGene Protein Over-expression Lysate for SOX30  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for SOX30  
     OriGene qSTAR qPCR primer pairs in human, mouse for SOX30   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for SOX30   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SOX30   OriGene Custom Protein Services for SOX30  

     
     
     Block miRNA regulation of human, mouse, rat SOX30 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing SOX30
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SOX30 Predesigned siRNA for gene silencing in human, mouse, rat SOX30
     QuantiFast Probe-based Assays in human, mouse, rat SOX30 QuantiTect SYBR Green Assays in human, mouse, rat SOX30
     Custom PCR Arrays for SOX30 Search Chromatin IP Primers for SOX30
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SOX30  Search GeneGlobe Interaction Network for SOX30
     Regulatory tfbs in SOX30 promoter
     GenScript Custom Purified and Recombinant Proteins Services for SOX30 GenScript cDNA clones with any tag delivered in your preferred vector for SOX30
     GenScript Custom Assay Services for SOX30 GenScript Custom overexpressing Cell Line Services for SOX30
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for SOX30
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     SOX30 antibodies
     SOX30 proteins
     SOX30 lysates
     Antibodies for SOX30
     See all of Abcam's Antibodies, Kits and Proteins for SOX30
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for SOX30
     Antibodies for SOX30
     ELISAs for SOX30
     CLIAs for SOX30



     Browse ESI BIO Cell Lines and PureStem Progenitors for SOX30
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SOX30
     SwitchGear 3'UTR luciferase reporter plasmids for SOX30
     SwitchGear Promoter luciferase reporter plasmids for SOX30
     ThermoFisher Antibodies for SOX30
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SOX30
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SOX30
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SOX30
     LSBio Antibodies in human, mouse, rat for SOX30
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for SOX30
      Search eBioscience for proteins for SOX30
      Search eBioscience for elisas for SOX30
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      SOX30 gene at Home site.
    Version: 3.12.202 14 Sep 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4