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SOX21 Gene

protein-coding   GIFtS: 50
GCID: GC13M095361

SRY (Sex Determining Region Y)-Box 21

  Search for SOX21
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
SRY (Sex Determining Region Y)-Box 211 2
SRY-Box 211 2
SOX-A2 3
SOX252 3
Transcription Factor SOX-212
SOXA3

External Ids:    HGNC: 111971   Entrez Gene: 111662   Ensembl: ENSG000001252857   OMIM: 6049745   UniProtKB: Q9Y6513   

Export aliases for SOX21 gene to outside databases

Previous GC identifers: GC13M093723 GC13M089750 GC13M094200 GC13M093061 GC13M094159 GC13M075959


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SOX21 Gene:
SRY-related HMG-box (SOX) genes encode a family of DNA-binding proteins containing a 79-amino acid HMG (high
mobility group) domain that shares at least 50% sequence identity with the DNA-binding HMG box of the SRY protein
(MIM 480000). SOX proteins are divided into 6 subgroups based on sequence similarity within and outside of the
HMG domain. For additional background information on SOX genes, see SOX1 (MIM 602148).(supplied by OMIM, Apr
2004)

GeneCards Summary for SOX21 Gene:
SOX21 (SRY (sex determining region Y)-box 21) is a protein-coding gene. GO annotations related to this gene include sequence-specific DNA binding RNA polymerase II transcription factor activity and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is SOX13.

UniProtKB/Swiss-Prot: SOX21_HUMAN, Q9Y651
Function: May play a role as an activator of transcription of OPRM1 (By similarity)

Gene Wiki entry for SOX21 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000013.10  NC_018924.2  NT_009952.15  
Regulatory elements:
   Regulatory transcription factor binding sites in the SOX21 gene promoter:
         Sox5   Sp1   COMP1   Chx10   IRF-7A   CUTL1   POU6F1 (c2)   Egr-4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSOX21 promoter sequence
   Search Chromatin IP Primers for SOX21

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SOX21


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q31-q32   Ensembl cytogenetic band:  13q32.1   HGNC cytogenetic band: 13q31-q32

SOX21 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SOX21 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13M095361:  view genomic region     (about GC identifiers)

Start:
95,361,876 bp from pter      End:
95,364,389 bp from pter
Size:
2,514 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SOX21_HUMAN, Q9Y651 (See protein sequence)
Recommended Name: Transcription factor SOX-21  
Size: 276 amino acids; 28580 Da
Secondary accessions: P35715 Q15504 Q5TBS1

Explore the universe of human proteins at neXtProt for SOX21: NX_Q9Y651

Explore proteomics data for SOX21 at MOPED


See SOX21 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_009015.1  
ENSEMBL proteins: 
 ENSP00000366144  

SOX21 Human Recombinant Protein Products:

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Cloud-Clone Corp. Proteins for SOX21

 
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Abcam antibodies for SOX21
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LSBio Antibodies in human, mouse, rat for SOX21

SOX21 Assay Products:

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Cloud-Clone Corp. ELISAs for SOX21
Cloud-Clone Corp. CLIAs for SOX21
Search eBioscience for ELISAs for SOX21 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
SOX: SRY (sex determining region Y)-boxes

2 InterPro protein domains:
 IPR009071 HMG_box_dom
 IPR022097 TF_SOX

Graphical View of Domain Structure for InterPro Entry Q9Y651

ProtoNet protein and cluster: Q9Y651

UniProtKB/Swiss-Prot: SOX21_HUMAN, Q9Y651
Similarity: Contains 1 HMG box DNA-binding domain


Find genes that share domains with SOX21           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: SOX21_HUMAN, Q9Y651
Function: May play a role as an activator of transcription of OPRM1 (By similarity)

     Genatlas biochemistry entry for SOX21:
SRY related HMG box gene 221,involved in embryonic CNS development,modulator of LINE retroposons promoter activity

     Gene Ontology (GO): 3 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0000981sequence-specific DNA binding RNA polymerase II transcription factor activity NAS10441749
GO:0003677DNA binding ISS--
GO:0003700sequence-specific DNA binding transcription factor activity ISS--
     
Find genes that share ontologies with SOX21           About GenesLikeMe


Phenotypes:
     2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Sox21):
 endocrine/exocrine gland  integument 

Find genes that share phenotypes with SOX21           About GenesLikeMe

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SOX21
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SOX21

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SOX21
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SOX21

miRNA
Products:
    
Block miRNA regulation of human, mouse, rat SOX21 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate SOX21 (see all 49):
hsa-miR-549 hsa-miR-19b-2* hsa-miR-578 hsa-miR-301a hsa-miR-759 hsa-miR-519a hsa-miR-3613-3p hsa-miR-29a*
SwitchGear 3'UTR luciferase reporter plasmidSOX21 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for SOX21
Predesigned siRNA for gene silencing in human, mouse, rat SOX21

Gene Editing
Products:
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Clone
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OriGene clones in human, mouse for SOX21 (see all 6)
OriGene ORF clones in mouse, rat for SOX21
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: SOX21 (NM_007084)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for SOX21
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SOX21

Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SOX21


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
SOX21_HUMAN, Q9Y651: Nucleus (By similarity)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
nucleus3
mitochondrion1

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005575cellular_component ND--
GO:0005634nucleus IEA--

Find genes that share ontologies with SOX21           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for SOX21 About    
See pathways by source

SuperPathContained pathways About
1ERK Signaling
Molecular Mechanisms of Cancer0.51

1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for SOX21
    Molecular Mechanisms of Cancer


    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SOX21
Interactions:

    Search GeneGlobe Interaction Network for SOX21

STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

4 Interacting proteins for SOX21 (ENSP000003661444) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
CHTF18ENSP000002623154STRING: ENSP00000262315
TAF2ENSP000003674064STRING: ENSP00000367406
TAF8ENSP000003620684STRING: ENSP00000362068
MSH2ENSP000002331464STRING: ENSP00000233146
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Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0001942hair follicle development IEA--
GO:0006355regulation of transcription, DNA-templated ISS--
GO:0006357regulation of transcription from RNA polymerase II promoter NAS10441749
GO:0006366transcription from RNA polymerase II promoter NAS10441749
GO:0042633hair cycle ----

Find genes that share ontologies with SOX21           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for SOX21



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for SOX21 gene: 
NM_007084.2  

Unigene Cluster for SOX21:

SRY (sex determining region Y)-box 21
Hs.187577  [show with all ESTs]
Unigene Representative Sequence: NM_007084
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000376945(uc001vma.3)
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat SOX21 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate SOX21 (see all 49):
hsa-miR-549 hsa-miR-19b-2* hsa-miR-578 hsa-miR-301a hsa-miR-759 hsa-miR-519a hsa-miR-3613-3p hsa-miR-29a*
SwitchGear 3'UTR luciferase reporter plasmidSOX21 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for SOX21
Predesigned siRNA for gene silencing in human, mouse, rat SOX21
Clone
Products:
     
OriGene clones in human, mouse for SOX21 (see all 6)
OriGene ORF clones in mouse, rat for SOX21
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: SOX21 (NM_007084)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for SOX21
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SOX21
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for SOX21
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SOX21
  QuantiTect SYBR Green Assays in human, mouse, rat SOX21
  QuantiFast Probe-based Assays in human, mouse, rat SOX21

Additional mRNA sequence: 

X65666.1 X71136.1 

1 DOTS entry:

DT.40299601 

12 AceView cDNA sequences:

AI201812 BM783159 NM_007084 AI884987 X71136 AI816765 X65666 AI569726 
AI418194 BF940869 AI869218 AA040785 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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SOX21 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: TATTTAGTTT
SOX21 Expression
About this image


SOX21 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 5) fully expand
 
 Epithelial Cells
         Fetal Medulla Cells Hair Shaft
 
 Hair (Integumentary System)    fully expand to see all 5 entries
         Fetal Medulla Cells Hair Shaft
 
 Brain (Nervous System)    fully expand to see all 2 entries
         Endothelial Cells Blood Brain Barrier
 
 Endothelium (Cardiovascular System)
         Endothelial Cells Blood Brain Barrier
 
 Neural Tube (Nervous System)
         Telencephalon
SOX21 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

SOX21 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.187577
    Custom PCR Arrays for SOX21
Primer
Products:
OriGene qSTAR qPCR primer pairs in human, mouse for SOX21
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SOX21
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QuantiFast Probe-based Assays in human, mouse, rat SOX21
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SOX21

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for SOX21 gene from Selected species (see all 12)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Sox211 , 5 SRY-box containing gene 215
SRY (sex determining region Y)-box 211
93.36(n)1
99.64(a)1
  14 (61.92 cM)5
2232271  NM_177753.31  NP_808421.11 
 1182332325 
lizard
(Anolis carolinensis)
Reptilia SOX216
SRY (sex determining region Y)-box 21
75(a)
1 ↔ 1
3(84855418-84856257)
tropical clawed frog
(Xenopus tropicalis)
Amphibia sox211 SRY (sex determining region Y)-box 21 74.03(n)
86.05(a)
  100038091  XM_002939280.2  XP_002939326.1 
zebrafish
(Danio rerio)
Actinopterygii sox21b1 SRY-box containing gene 21 b 71.33(n)
80.93(a)
  406246  NM_001009888.2  NP_001009888.1 
fruit fly
(Drosophila melanogaster)
Insecta Sox21a3 transcription factor 91(a)
(best of 3)
  70D2   --
worm
(Caenorhabditis elegans)
Secernentea sox-36
Protein SOX-3 (sox-3) mRNA, complete cds
42(a)
1 → many
X(14690833-14692999) WBGene00004950


ENSEMBL Gene Tree for SOX21 (if available)
TreeFam Gene Tree for SOX21 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for SOX21 gene
SOX132  SOX22  SOX42  SOX12  SOX142  SOX32  SOX92  SOX122  
SOX152  SOX182  SOX52  ENSG000002587242  SOX172  SOX62  SOX112  SOX82  
SRY2  SOX102  SOX72  
10 SIMAP similar genes for SOX21 using alignment to 1 protein entry:     SOX21_HUMAN:
soxB    SRY    SOX17    SOX15    SOX14    SOX10
SOX11    SOX3    SOX1    SOX2

Find genes that share paralogs with SOX21           About GenesLikeMe



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for SOX21 (see all 42)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 13 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1502824451,2
--95361448(+) AAGGAA/CTACCC 1 -- int10--------
rs1876603481,2
--95361556(+) AGAAAC/TTGGTG 1 -- int10--------
rs726384021,2
--95361592(+) TTCAAC/TGGGCT 1 -- int10--------
rs2006264041,2
C--95361621(+) ATGCC-/TTTTTT 1 -- int10--------
rs1179189841,2
F--95361627(+) TTTTTT/GTTGTT 1 -- int11Minor allele frequency- G:0.01EA 120
rs726398031,2
C--95361659(+) ACTTGC/GGCTTT 1 -- int10--------
rs1417704321,2
--95361723(+) GCTCTG/TAATAA 1 -- int10--------
rs1470816941,2
C--95361931(+) ATGAAC/GAGAGT 1 -- ut310--------
rs1906854741,2
--95361995(+) AAGGTC/TACACT 1 -- ut310--------
rs735504791,2
C--95362035(+) CCATAT/CTTAAA 1 -- ut313Minor allele frequency- C:0.12WA CSA 121

HapMap Linkage Disequilibrium report for SOX21 (95361876 - 95364389 bp)

Structural Variations
     Database of Genomic Variants (DGV) 4 variations for SOX21:    About this table    
Variant IDTypeSubtypePubMed ID
esv34004CNV Loss18971310
esv28079CNV Loss19812545
nsv826750CNV Gain20364138
nsv832686CNV Gain17160897

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing SOX21
DNA2.0 Custom Variant and Variant Library Synthesis for SOX21

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 604974    OMIM disorders: --


Find genes that share disorders with SOX21           About GenesLikeMe


Export disorders for SOX21 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for SOX21 gene, integrated from 10 sources (see all 16):
(articles sorted by number of sources associating them with SOX21)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The isolation and high-resolution chromosomal mapping of human SOX14 and SOX21; two members of the SOX gene family related to SOX1, SOX2, and SOX3. (PubMed id 10441749)1, 2, 3 Malas S.... Episkopou V. (Mamm. Genome 1999)
  2. A conserved family of genes related to the testis determining gene, SRY. (PubMed id 1614875)1, 2 Denny P.... Ashworth A. (Nucleic Acids Res. 1992)
  3. Sox21 inhibits glioma progression in vivo by forming complexes with Sox2 and stimulating aberrant differentiation. (PubMed id 23463365)1 Caglayan D....Ferletta M. (Int. J. Cancer 2013)
  4. Forced expression of Sox21 inhibits Sox2 and induces apoptosis in human glioma cells. (PubMed id 20824710)1 Ferletta M....Westermark B. (Int. J. Cancer 2011)
  5. Transcriptome analysis of human gastric cancer. (PubMed id 16341674)1 Oh J.H.... Kim N.S. (Mamm. Genome 2005)
  6. The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)2 Dunham A.... Ross M.T. (Nature 2004)
  7. Twenty pairs of sox: extent, homology, and nomenclature of the mouse and human sox transcription factor gene families. (PubMed id 12194848)1 Schepers G.E....Koopman P. (Dev. Cell 2002)
  8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  9. DNA cloning using in vitro site-specific recombination. (PubMed id 11076863)1 Hartley J.L....Brasch M.A. (Genome Res. 2000)
  10. Further complexity of the human SOX gene family revealed by the combined use of highly degenerate primers and nested PCR. (PubMed id 9827568)1 Cremazy F.... Jay P. (FEBS Lett. 1998)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 11166 HGNC: 11197 AceView: SOX21 Ensembl:ENSG00000125285 euGenes: HUgn11166
ECgene: SOX21 H-InvDB: SOX21

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for SOX21 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for SOX21 gene:
Search GeneIP for patents involving SOX21

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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 EMD Millipore genomic analysis products

  
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