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SOX14 Gene

protein-coding   GIFtS: 52
GCID: GC03P137483

SRY (Sex Determining Region Y)-Box 14

  See SOX14-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
SRY (Sex Determining Region Y)-Box 141 2
HMG Box Transcription Factor SOX-141 2
SRY-Box 141 2
SOX282 3
Transcription Factor SOX-142
Protein SOX-283

External Ids:    HGNC: 111931   Entrez Gene: 84032   Ensembl: ENSG000001688757   OMIM: 6047475   UniProtKB: O954163   

Export aliases for SOX14 gene to outside databases

Previous GC identifers: GC03P134468 GC03P138275 GC03P138765 GC03P138804 GC03P138966 GC03P134858


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SOX14 Gene:
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in
the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as
a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene are
suggested to be responsible for the limb defects associated with blepharophimosis, ptosis, epicanthus inversus
syndrome (BPES) and Mobius syndrome. (provided by RefSeq, Jul 2008)

GeneCards Summary for SOX14 Gene:
SOX14 (SRY (sex determining region Y)-box 14) is a protein-coding gene. Diseases associated with SOX14 include papillon-lefevre disease, and mobius syndrome. GO annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is SOX13.

UniProtKB/Swiss-Prot: SOX14_HUMAN, O95416
Function: Acts as a negative regulator of transcription (By similarity)

Gene Wiki entry for SOX14 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000003.11  NC_018914.2  NT_005612.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the SOX14 gene promoter:
         Max1   MEF-2   RelA   NF-kappaB   PPAR-alpha   MEF-2A   POU2F1   aMEF-2   NF-kappaB1   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSOX14 promoter sequence
   Search Chromatin IP Primers for SOX14

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SOX14


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q22-q23   Ensembl cytogenetic band:  3q22.3   HGNC cytogenetic band: 3q22-q23

SOX14 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SOX14 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P137483:  view genomic region     (about GC identifiers)

Start:
137,483,134 bp from pter      End:
137,485,176 bp from pter
Size:
2,043 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: SOX14_HUMAN, O95416 (See protein sequence)
Recommended Name: Transcription factor SOX-14  
Size: 240 amino acids; 26485 Da
Secondary accessions: B2RAC0 Q3KPH7

Explore the universe of human proteins at neXtProt for SOX14: NX_O95416

Explore proteomics data for SOX14 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SOX14 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_004180.1  
    ENSEMBL proteins: 
     ENSP00000305343  

    SOX14 Human Recombinant Protein Products:

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    Novus Biologicals SOX14 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SOX14

     
    Search eBioscience for Proteins for SOX14 

     
    antibodies-online proteins for SOX14 (4 products) 

     
    antibodies-online peptides for SOX14

    SOX14 Antibody Products:

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    LSBio Antibodies in human, mouse, rat for SOX14
    antibodies-online antibodies for SOX14 (28 products) 

    SOX14 Assay Products:

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    Cloud-Clone Corp. ELISAs for SOX14
    Cloud-Clone Corp. CLIAs for SOX14
    Search eBioscience for ELISAs for SOX14 
    antibodies-online kits for SOX14 (6 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SOX: SRY (sex determining region Y)-boxes

    2 InterPro protein domains:
     IPR009071 HMG_box_dom
     IPR022097 TF_SOX

    Graphical View of Domain Structure for InterPro Entry O95416

    ProtoNet protein and cluster: O95416

    UniProtKB/Swiss-Prot: SOX14_HUMAN, O95416
    Similarity: Contains 1 HMG box DNA-binding domain


    Find genes that share domains with SOX14           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SOX14_HUMAN, O95416
    Function: Acts as a negative regulator of transcription (By similarity)

         Genatlas biochemistry entry for SOX14:
    SRY related HMG box gene 14,predominantly expressed in fetal brain,spinal cord,thymus,potentially involved in
    regulation of nervous system development,modulator of LINE retroposons promoter activity

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0043565sequence-specific DNA binding ISS--
         
    Find genes that share ontologies with SOX14           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for SOX14:
     Decreased NANOG protein expres  Decreased OCT4 protein express  Decreased POU5F1-GFP protein e 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Sox14):
     no phenotypic analysis 

    Find genes that share phenotypes with SOX14           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SOX14
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SOX14

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SOX14
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SOX14

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat SOX14 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SOX14 (see all 19):
    hsa-miR-548j hsa-miR-548i hsa-miR-24-1* hsa-miR-4272 hsa-miR-219-5p hsa-miR-500a hsa-miR-24-2* hsa-miR-511
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SOX14

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for SOX14

    Clone
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    OriGene clones in human, mouse for SOX14 (see all 5)
    OriGene ORF clones in mouse, rat for SOX14
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    GenScript: all cDNA clones in your preferred vector: SOX14 (NM_004189)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SOX14
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SOX14

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SOX14


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SOX14_HUMAN, O95416: Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005634nucleus IEA--

    Find genes that share ontologies with SOX14           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SOX14 About    
    See pathways by source

    SuperPathContained pathways About
    1ERK Signaling
    Molecular Mechanisms of Cancer0.51

    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for SOX14
        Molecular Mechanisms of Cancer


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SOX14
    Interactions:

        Search GeneGlobe Interaction Network for SOX14

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for SOX14 (ENSP000003053434) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CHTF18ENSP000002623154STRING: ENSP00000262315
    TAF2ENSP000003674064STRING: ENSP00000367406
    TAF8ENSP000003620684STRING: ENSP00000362068
    MSH2ENSP000002331464STRING: ENSP00000233146
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter ISS--
    GO:0006351transcription, DNA-templated IEA--
    GO:0007399nervous system development TAS9925951
    GO:0045892negative regulation of transcription, DNA-templated ISS--

    Find genes that share ontologies with SOX14           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SOX14



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SOX14 gene: 
    NM_004189.3  

    Unigene Cluster for SOX14:

    SRY (sex determining region Y)-box 14
    Hs.248184  [show with all ESTs]
    Unigene Representative Sequence: NM_004189
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000306087(uc003erm.2)
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate SOX14 (see all 19):
    hsa-miR-548j hsa-miR-548i hsa-miR-24-1* hsa-miR-4272 hsa-miR-219-5p hsa-miR-500a hsa-miR-24-2* hsa-miR-511
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for SOX14
    Predesigned siRNA for gene silencing in human, mouse, rat SOX14
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    OriGene clones in human, mouse for SOX14 (see all 5)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SOX14
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for SOX14
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SOX14
      QuantiTect SYBR Green Assays in human, mouse, rat SOX14
      QuantiFast Probe-based Assays in human, mouse, rat SOX14

    Additional mRNA sequence: 

    AK314127.1 BC106729.1 BC106730.1 

    1 DOTS entry:

    DT.91734375 

    5 AceView cDNA sequences:

    NM_004189 BX416919 BX430903 BQ025639 BQ022364 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SOX14 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAACCCCCAG
    SOX14 Expression
    About this image


    SOX14 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Thalamus
    SOX14 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SOX14 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.248184
        Custom PCR Arrays for SOX14
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for SOX14
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SOX14

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SOX14 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sox141 , 5 SRY-box containing gene 145
    SRY (sex determining region Y)-box 141
    95.42(n)1
    99.58(a)1
      9 (52.11 cM)5
    206691  NM_011440.11  NP_035570.11 
     998741065 
    chicken
    (Gallus gallus)
    Aves SOX141 SRY (sex determining region Y)-box 14 84.44(n)
    96.25(a)
      395526  NM_204761.1  NP_990092.1 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia sox141 SRY (sex determining region Y)-box 14 77.13(n)
    89.12(a)
      100101715  NM_001100233.1  NP_001093703.1 
    zebrafish
    (Danio rerio)
    Actinopterygii AF101266.12   -- 78.71(n)   30543  AF101266.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Sox21a3 transcription factor 90(a)
    (best of 3)
      70D2   --
    worm
    (Caenorhabditis elegans)
    Secernentea sox-36
    Protein SOX-3 (sox-3) mRNA, complete cds
    39(a)
    1 → many
    X(14690833-14692999) WBGene00004950


    ENSEMBL Gene Tree for SOX14 (if available)
    TreeFam Gene Tree for SOX14 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SOX14 gene
    SOX132  SOX22  SOX42  SOX12  SOX32  SOX92  SOX122  SOX152  
    SOX182  SOX52  ENSG000002587242  SOX212  SOX172  SOX62  SOX112  SOX82  
    SRY2  SOX102  SOX72  
    13 SIMAP similar genes for SOX14 using alignment to 1 protein entry:     SOX14_HUMAN:
    SOX25    soxB    SOX11    SOX10    SOX17    SRY
    SOX5    SOX21    SOX15    SOX2    SOX12    SOX1
    SOX8

    Find genes that share paralogs with SOX14           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SOX14 (see all 86)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs801473091,2
    F--137481265(+) GCACCG/TCTGGT 1 -- us2k11Minor allele frequency- T:0.03WA 118
    rs1822900031,2
    --137481290(+) GGTTGA/CCAGCG 1 -- us2k10--------
    rs126369281,2
    C,F,H--137481332(+) AAAGTG/ACGTTT 1 -- us2k110Minor allele frequency- A:0.07NS EA NA WA 658
    rs168474331,2
    C,F,H--137481342(+) TGCTTC/TCTGAG 1 -- us2k1 tfbs325Minor allele frequency- T:0.07NA NS EA WA 2788
    rs1404193101,2
    --137481390(+) GGTTAC/GAGGGC 1 -- us2k10--------
    rs1866161731,2
    --137481399(+) GCTGGA/TTGGAG 1 -- us2k10--------
    rs1454254141,2
    --137481423(+) GCCAGA/CGCTGG 1 -- us2k10--------
    rs117173371,2
    C,F,H--137481510(+) CGCAGG/AATCAG 1 -- us2k129Minor allele frequency- A:0.07NA NS EA 3028
    rs1380298981,2
    C--137481562(+) CCCAAC/TAGTCT 1 -- us2k10--------
    rs1925552071,2
    --137481574(+) ATCAGG/TTGTTC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SOX14 (137483134 - 137485176 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for SOX14:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv428422CNV Gain+Loss18775914

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SOX14
    DNA2.0 Custom Variant and Variant Library Synthesis for SOX14

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 604747    OMIM disorders: --

    3 diseases for SOX14:    
    About MalaCards
    papillon-lefevre disease    mobius syndrome    blepharophimosis, ptosis, and epicanthus inversus syndrome

    4 diseases from the University of Copenhagen DISEASES database for SOX14:
    Mobius syndrome     blepharophimosis, ptosis, and epicanthus inversus syndrome     Papillon-Lefevre disease     Blepharophimosis

    Find genes that share disorders with SOX14           About GenesLikeMe

    Genetic Association Database (GAD): SOX14
    Human Genome Epidemiology (HuGE) Navigator: SOX14 (1 document)

    Export disorders for SOX14 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SOX14 gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with SOX14)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterisation and mapping of the human SOX14 gene. (PubMed id 9925951)1, 2, 3 Arsic N.... Stevanovic M. (Cytogenet. Cell Genet. 1998)
    2. Fine mapping of the neurally expressed gene SOX14 to human 3q23, relative to three congenital diseases. (PubMed id 10830911)1, 2, 9 Hargrave M.... Koopman P. (Hum. Genet. 2000)
    3. Analysis of copy number variation in 8,842 Korean individuals reveals 39 genes associated with hepatic biomarkers AST and ALT. (PubMed id 20797317)1, 4 Kim H.Y....Kim H. (BMB Rep 2010)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. The isolation and high-resolution chromosomal mapping of human SOX14 and SOX21; two members of the SOX gene family related to SOX1, SOX2, and SOX3. (PubMed id 10441749)1, 2 Malas S.... Episkopou V. (Mamm. Genome 1999)
    6. Further complexity of the human SOX gene family revealed by the combined use of highly degenerate primers and nested PCR. (PubMed id 9827568)1, 2 Cremazy F.... Jay P. (FEBS Lett. 1998)
    7. Tissue-specific Forkhead protein FOXA2 up-regulates SOX14 gene expression. (PubMed id 20074681)1 Popovic J....Stevanovic M. (Biochim. Biophys. Acta 2010)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
    9. Matching SOX: partner proteins and co-factors of the SOX family of transcriptional regulators. (PubMed id 12100890)1 Wilson M. and Koopman P. (amp 2002)
    10. Twenty pairs of sox: extent, homology, and nomenclature of the mouse and human sox transcription factor gene families. (PubMed id 12194848)1 Schepers G.E....Koopman P. (Dev. Cell 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 8403 HGNC: 11193 AceView: SOX14 Ensembl:ENSG00000168875 euGenes: HUgn8403
    ECgene: SOX14 H-InvDB: SOX14

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SOX14 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SOX14 gene:
    Search GeneIP for patents involving SOX14

    GeneCards and IP:
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