Aliases for SOX11 Gene
External Ids for SOX11 Gene
Previous GeneCards Identifiers for SOX11 Gene
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis. [provided by RefSeq, Jul 2008]
GeneCards Summary for SOX11 Gene
SOX11 (SRY (Sex Determining Region Y)-Box 11) is a Protein Coding gene. Diseases associated with SOX11 include mental retardation, autosomal dominant, 27 and coffin-siris syndrome. Among its related pathways are ERK Signaling. GO annotations related to this gene include RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and RNA polymerase II core promoter sequence-specific DNA binding. An important paralog of this gene is SOX3.
UniProtKB/Swiss-Prot for SOX11 Gene
Transcriptional factor involved in the embryonic neurogenesis. May also have a role in tissue modeling during development.