External Ids for SOX1 Gene
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development. [provided by RefSeq, Jul 2008]
GeneCards Summary for SOX1 Gene
SOX1 (SRY (Sex Determining Region Y)-Box 1) is a Protein Coding gene. Diseases associated with SOX1 include lung cancer. Among its related pathways are ERK Signaling and Cardiac Progenitor Differentiation. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and core promoter sequence-specific DNA binding. An important paralog of this gene is SOX3.
UniProtKB/Swiss-Prot for SOX1 Gene
Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).