Aliases for SOX1 Gene
External Ids for SOX1 Gene
Previous GeneCards Identifiers for SOX1 Gene
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development. [provided by RefSeq, Jul 2008]
GeneCards Summary for SOX1 Gene
SOX1 (SRY-Box 1) is a Protein Coding gene. Among its related pathways are Cardiac Progenitor Differentiation and ERK Signaling. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and core promoter sequence-specific DNA binding. An important paralog of this gene is SOX3.
UniProtKB/Swiss-Prot for SOX1 Gene
Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).