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Aliases for SOWAHD Gene

Aliases for SOWAHD Gene

  • Sosondowah Ankyrin Repeat Domain Family Member D 2 3 5
  • Ankyrin Repeat Domain-Containing Protein 58 3 4
  • Protein Sosondowah Homolog D 3 4
  • Ankyrin Repeat Domain 58 2 3
  • ANKRD58 3 4
  • Ankyrin Repeat Domain-Containing Protein SOWAHD 3

External Ids for SOWAHD Gene

Previous HGNC Symbols for SOWAHD Gene

  • ANKRD58

Previous GeneCards Identifiers for SOWAHD Gene

  • GC0XP118893

Summaries for SOWAHD Gene

GeneCards Summary for SOWAHD Gene

SOWAHD (Sosondowah Ankyrin Repeat Domain Family Member D) is a Protein Coding gene. An important paralog of this gene is SOWAHC.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SOWAHD Gene

Genomics for SOWAHD Gene

Regulatory Elements for SOWAHD Gene

Enhancers for SOWAHD Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XG119753 1.3 FANTOM5 ENCODE 7.7 -2.0 -2034 5.9 HDGF PKNOX1 WRNIP1 ARID4B SIN3A DMAP1 ZNF48 ZNF121 GLIS2 ELK1 MIR766 SOWAHD UPF3B RNF113A NDUFA1 SEPT6 ZBTB33 PIR44405
GH0XG119762 0.7 ENCODE 0.7 +4.8 4773 1.3 CEBPB ZNF223 CEBPG TEAD3 ZNF121 ZFHX2 JUND GLIS1 IKZF1 CEBPA RNF113A NDUFA1 UPF3B SLC25A43 SOWAHD SNORA69 GC0XM119789 GC0XM119788
GH0XG119759 0.7 ENCODE 0.7 +1.4 1443 0.9 BCOR MTA2 NR2F1 ZMYM3 REST EBF1 UBTF TBX21 POLR2A IKZF1 RNF113A NDUFA1 UPF3B SOWAHD SNORA69 GC0XM119789 GC0XM119788
GH0XG119760 0.5 ENCODE 0.7 +2.1 2060 0.2 MTA2 IKZF1 RELB NDUFA1 RNF113A SOWAHD GC0XM119789 GC0XM119788 SNORA69
GH0XG119775 0.8 Ensembl ENCODE 0.4 +17.1 17122 1.2 POLR2A EED IKZF1 MLLT1 IKZF2 PRDM1 SPI1 RHOXF1-AS1 GC0XM119788 GC0XM119789 SNORA69 SOWAHD
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SOWAHD on UCSC Golden Path with GeneCards custom track

Promoters for SOWAHD Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000248367 387 2001 ARID4B DMAP1 ZNF48 GLIS2 KLF7 ZNF263 ZNF202 SP3 SP5 REST

Genomic Location for SOWAHD Gene

Chromosome:
X
Start:
119,758,613 bp from pter
End:
119,760,202 bp from pter
Size:
1,590 bases
Orientation:
Plus strand

Genomic View for SOWAHD Gene

Genes around SOWAHD on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SOWAHD Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SOWAHD Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SOWAHD Gene

Proteins for SOWAHD Gene

  • Protein details for SOWAHD Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NJG2-SWAHD_HUMAN
    Recommended name:
    Ankyrin repeat domain-containing protein SOWAHD
    Protein Accession:
    A6NJG2

    Protein attributes for SOWAHD Gene

    Size:
    315 amino acids
    Molecular mass:
    33803 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SOWAHD Gene

Post-translational modifications for SOWAHD Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SOWAHD Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SOWAHD Gene

Domains & Families for SOWAHD Gene

Gene Families for SOWAHD Gene

Protein Domains for SOWAHD Gene

Suggested Antigen Peptide Sequences for SOWAHD Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NJG2

UniProtKB/Swiss-Prot:

SWAHD_HUMAN :
  • Belongs to the SOWAH family.
Family:
  • Belongs to the SOWAH family.
genes like me logo Genes that share domains with SOWAHD: view

Function for SOWAHD Gene

Phenotypes for SOWAHD Gene

genes like me logo Genes that share phenotypes with SOWAHD: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SOWAHD Gene

Localization for SOWAHD Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SOWAHD gene
Compartment Confidence
mitochondrion 2
peroxisome 1
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for SOWAHD Gene

Pathways & Interactions for SOWAHD Gene

SuperPathways for SOWAHD Gene

No Data Available

Interacting Proteins for SOWAHD Gene

Gene Ontology (GO) - Biological Process for SOWAHD Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SOWAHD Gene

Drugs & Compounds for SOWAHD Gene

No Compound Related Data Available

Transcripts for SOWAHD Gene

mRNA/cDNA for SOWAHD Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
-
(11) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SOWAHD Gene

Sosondowah ankyrin repeat domain family member D:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SOWAHD Gene

No ASD Table

Relevant External Links for SOWAHD Gene

GeneLoc Exon Structure for
SOWAHD
ECgene alternative splicing isoforms for
SOWAHD

Expression for SOWAHD Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SOWAHD Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SOWAHD Gene

This gene is overexpressed in Whole Blood (x12.3), Spleen (x8.2), Testis (x5.2), and Small Intestine - Terminal Ileum (x4.4).

Protein differential expression in normal tissues from HIPED for SOWAHD Gene

This gene is overexpressed in Bone (40.3), Pancreas (10.4), and Testis (9.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SOWAHD Gene



Protein tissue co-expression partners for SOWAHD Gene

NURSA nuclear receptor signaling pathways regulating expression of SOWAHD Gene:

SOWAHD

SOURCE GeneReport for Unigene cluster for SOWAHD Gene:

Hs.355223
genes like me logo Genes that share expression patterns with SOWAHD: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SOWAHD Gene

Orthologs for SOWAHD Gene

This gene was present in the common ancestor of animals.

Orthologs for SOWAHD Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SOWAHD 34
  • 96.84 (n)
cow
(Bos Taurus)
Mammalia SOWAHD 34 35
  • 83.07 (n)
mouse
(Mus musculus)
Mammalia Sowahd 34 16 35
  • 70.85 (n)
rat
(Rattus norvegicus)
Mammalia Sowahd 34
  • 69.52 (n)
chicken
(Gallus gallus)
Aves SOWAHD 35
  • 40 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SOWAHD 35
  • 27 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii SOWAHD 35
  • 25 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta sowah 35
  • 8 (a)
OneToMany
Species where no ortholog for SOWAHD was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SOWAHD Gene

ENSEMBL:
Gene Tree for SOWAHD (if available)
TreeFam:
Gene Tree for SOWAHD (if available)

Paralogs for SOWAHD Gene

Paralogs for SOWAHD Gene

genes like me logo Genes that share paralogs with SOWAHD: view

Variants for SOWAHD Gene

Sequence variations from dbSNP and Humsavar for SOWAHD Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs1002114254 -- 119,759,240(+) CCCCT(C/T)CACCT reference, synonymous-codon
rs1002710021 -- 119,757,511(+) CAACC(C/T)CCATC upstream-variant-2KB
rs1003288219 -- 119,759,595(+) TGTTC(C/T)CCTCA reference, missense
rs1005787973 -- 119,760,017(+) AAACC(A/C)CCAAT utr-variant-3-prime
rs1006004447 -- 119,759,736(+) AGGAA(C/G)AGAAC utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for SOWAHD Gene

Variant ID Type Subtype PubMed ID
nsv7056 CNV deletion 18451855

Variation tolerance for SOWAHD Gene

Gene Damage Index Score: 0.67; 14.23% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SOWAHD Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SOWAHD

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SOWAHD Gene

Disorders for SOWAHD Gene

Relevant External Links for SOWAHD

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SOWAHD

No disorders were found for SOWAHD Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SOWAHD Gene

Publications for SOWAHD Gene

  1. An ancient genomic regulatory block conserved across bilaterians and its dismantling in tetrapods by retrogene replacement. (PMID: 22234889) Maeso I. … Garcia-FernA ndez J. (Genome Res. 2012) 2 3 64
  2. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4 64

Products for SOWAHD Gene

Sources for SOWAHD Gene

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