SOWAHC Gene
protein-coding GIFtS: 37
GCID: GC02P110372
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sosondowah ankyrin repeat domain family member C(Previous name: ankyrin repeat domain 57 )
(Previous symbols: C2orf26, ANKRD57)
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Aliases
for SOWAHC gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Sosondowah Ankyrin Repeat Domain Family Member C1 2 | | Ankyrin Repeat Domain-Containing Protein 572 3 | | ANKRD571 2 3 | | Protein Sosondowah Homolog C2 3 | | C2orf261 2 3 | | FLJ218701 | | Ankyrin Repeat Domain 571 2 | | Ankyrin Repeat Domain-Containing Protein SOWAHC2 |
Export aliases for SOWAHC gene to outside databases |
Summaries
for SOWAHC gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for SOWAHC gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022135.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for SOWAHC
Other transcription factors
Search SABiosciences Chromatin IP Primers for SOWAHC
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SOWAHC |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q13 Ensembl cytogenetic band: 2q13 HGNC cytogenetic band: 2q13SOWAHC Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P110372: view genomic region
(about GC identifiers)
Start:
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110,371,911 bp from pter |
End:
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110,376,564 bp from pter |
Size:
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4,654 bases |
Orientation:
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plus strand |
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Proteins
for SOWAHC gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SWAHC_HUMAN, Q53LP3 (See
protein sequence)Recommended Name: Ankyrin repeat domain-containing protein SOWAHC Size: 525 amino acids; 55672 Da
Sequence caution: Sequence=BAB15161.1; Type=Frameshift; Positions=311;
Secondary accessions: Q8NE15 Q9H6U1Explore the universe of human proteins at neXtProt for SOWAHC: NX_Q53LP3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q53LP3
SOWAHC Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_075392.2
ENSEMBL proteins: ENSP00000365830
Human Recombinant Protein Products:
SOWAHC Antibody Products:
Assay Products for SOWAHC: |
Protein
Domains /
Families
for SOWAHC gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SOWAHC for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q53LP3ProtoNet protein and cluster: Q53LP3 UniProtKB/Swiss-Prot: SWAHC_HUMAN, Q53LP3Similarity: Belongs to the SOWAH familySimilarity: Contains 2 ANK repeats |
Function
for SOWAHC gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SOWAHC (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SOWAHC
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for SOWAHC | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SOWAHC | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SOWAHC |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SOWAHC |
|
Pathways & Interactions
for SOWAHC gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SOWAHC
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
3 Interacting proteins for SOWAHC (Q53LP33 ENSP000003658304) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for SOWAHC gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SOWAHC
Search CenterWatch for drugs/clinical trials and news about SOWAHC / SWAHC
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Transcripts
for SOWAHC gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SOWAHC gene: NM_023016.3 Unigene Cluster for SOWAHC: Sosondowah ankyrin repeat domain family member C Hs.355455 [show with all ESTs]Unigene Representative Sequence: NM_0230161 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000356454(uc002tfb.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SOWAHC (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SOWAHC
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for SOWAHC | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SOWAHC | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SOWAHC |
Additional cDNA sequence: AK023346.1 AK025523.1 BC036652.1 BC066772.1 3 DOTS entries: DT.87012556 DT.100678603 DT.95138527 24/99 AceView cDNA sequences (see all 99): CR622761 AW662149 AI003797 AI675284 AW161459 BX645211 BM994405 BQ437156 AV716967 R84563 AI478812 BU153173 AI589168 BQ025322 AA885692 AW161879 BX483394 CN479621 BU508918 AA936548 BF686132 BQ937551 AA987196 BM708838
GeneLoc Exon Structure
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Expression
for SOWAHC gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SOWAHC expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See SOWAHC Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SOWAHC
SOURCE GeneReport for Unigene cluster: Hs.355455
SABiosciences Custom PCR Arrays for SOWAHC
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SOWAHC
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat SOWAHC | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SOWAHC | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SOWAHC | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SOWAHC |
Orthologs
for SOWAHC gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of animals.
Orthologs for SOWAHC gene from 3/13 species (see all 13) About this table
ENSEMBL Gene Tree for SOWAHC (if available)
TreeFam Gene Tree for SOWAHC (if available) |
Paralogs
for SOWAHC gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SOWAHC gene
- SOWAHB2 SOWAHD2 SOWAHA2
SOWAHC for paralogs About GeneDecksing
4 Pseudogenes.org Pseudogenes for SOWAHC
PGOHUM00000238999 PGOHUM00000240780 PGOHUM00000262586 PGOHUM00000233738
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Genomic Variants
for SOWAHC gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for SOWAHC (110371911 - 110376564 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SOWAHC: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SOWAHC |
|
Disorders
/ Diseases
for SOWAHC gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for SOWAHC gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SOWAHC gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with SOWAHC) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- An ancient genomic regulatory block conserved across bilaterians and its dismantling in tetrapods by retrogene replacement. (PubMed id 22234889)1, 3 Maeso I....Garcia-FernA ndez J. (2012)
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
- An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (2010)
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External Searches for SOWAHC gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing SOWAHC gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing SOWAHC gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SOWAHC gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SOWAHC | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for SOWAHC gene:
Search GeneIP for patents involving SOWAHC
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SOWAHC gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SOWAHC | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SOWAHC | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SOWAHC | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SOWAHC | | OriGene 3'-UTR Clone for SOWAHC | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SOWAHC | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SOWAHC | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SOWAHC | | OriGene Custom Protein Services for SOWAHC | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SOWAHC | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SOWAHC | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SOWAHC | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SOWAHC | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SOWAHC | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SOWAHC |
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 |  |  |  | |
| | | | Search Tocris compounds for SOWAHC |
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 | | | SOWAHC Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SOWAHC |
|  |  |  | | | | ThermoFisher Antibodies for SOWAHC |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SOWAHC |
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