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Aliases for SOWAHB Gene

Aliases for SOWAHB Gene

  • Sosondowah Ankyrin Repeat Domain Family Member B 2 3 5
  • Ankyrin Repeat Domain-Containing Protein 56 3 4
  • Protein Sosondowah Homolog B 3 4
  • Ankyrin Repeat Domain 56 2 3
  • ANKRD56 3 4
  • Ankyrin Repeat Domain-Containing Protein SOWAHB 3

External Ids for SOWAHB Gene

Previous HGNC Symbols for SOWAHB Gene

  • ANKRD56

Previous GeneCards Identifiers for SOWAHB Gene

  • GC04M077817
  • GC04M077819
  • GC04M077824
  • GC04M077832
  • GC04M077838

Summaries for SOWAHB Gene

GeneCards Summary for SOWAHB Gene

SOWAHB (Sosondowah Ankyrin Repeat Domain Family Member B) is a Protein Coding gene. An important paralog of this gene is SOWAHA.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SOWAHB Gene

Genomics for SOWAHB Gene

Regulatory Elements for SOWAHB Gene

Enhancers for SOWAHB Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04F076896 0.5 ENCODE 45.3 +0.3 314 1.8 HDGF PKNOX1 CREB3L1 ARID4B SIN3A DMAP1 ZNF2 ZNF48 YY1 GLIS2 SOWAHB GC04P076892
GH04F076892 0.6 ENCODE 20.8 +5.3 5288 0.7 FOS SOWAHB GC04P076892
GH04F076855 0.7 Ensembl ENCODE 19.3 +41.3 41316 2.6 FEZF1 YY1 PPARG SMARCA4 RFX3 GLIS1 STAT3 HNF4A WT1 SP7 SOWAHB PIR31989 LOC105377289
GH04F076931 0.5 ENCODE 18.6 -33.1 -33096 0.2 OSR2 ZNF362 ZNF366 GLIS1 FOS SOWAHB GC04M076939
GH04F076830 1.2 FANTOM5 Ensembl ENCODE 14.9 +66.3 66345 3.1 PKNOX1 ATF1 MLX ARID4B DMAP1 YY1 ZNF121 ELK1 MIER2 PPARG SOWAHB ENSG00000224218 LOC105377289 PIR31989
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around SOWAHB on UCSC Golden Path with GeneCards custom track

Promoters for SOWAHB Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for SOWAHB Gene

76,894,928 bp from pter
76,898,147 bp from pter
3,220 bases
Minus strand

Genomic View for SOWAHB Gene

Genes around SOWAHB on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SOWAHB Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SOWAHB Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SOWAHB Gene

Proteins for SOWAHB Gene

  • Protein details for SOWAHB Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ankyrin repeat domain-containing protein SOWAHB
    Protein Accession:
    Secondary Accessions:
    • B2RP29

    Protein attributes for SOWAHB Gene

    793 amino acids
    Molecular mass:
    85742 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SOWAHB Gene

Post-translational modifications for SOWAHB Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SOWAHB Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SOWAHB Gene

Domains & Families for SOWAHB Gene

Gene Families for SOWAHB Gene

Protein Domains for SOWAHB Gene

Suggested Antigen Peptide Sequences for SOWAHB Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the SOWAH family.
  • Contains 2 ANK repeats.
  • Belongs to the SOWAH family.
  • Contains 2 ANK repeats.
genes like me logo Genes that share domains with SOWAHB: view

Function for SOWAHB Gene

Phenotypes for SOWAHB Gene

genes like me logo Genes that share phenotypes with SOWAHB: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SOWAHB Gene

Localization for SOWAHB Gene

Subcellular locations from

Jensen Localization Image for SOWAHB Gene COMPARTMENTS Subcellular localization image for SOWAHB gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for SOWAHB Gene

Pathways & Interactions for SOWAHB Gene

SuperPathways for SOWAHB Gene

No Data Available

Interacting Proteins for SOWAHB Gene

Selected Interacting proteins: A6NEL2-SWAHB_HUMAN for SOWAHB Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for SOWAHB Gene


No data available for Pathways by source and SIGNOR curated interactions for SOWAHB Gene

Transcripts for SOWAHB Gene


(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(11) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SOWAHB Gene

Sosondowah ankyrin repeat domain family member B:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SOWAHB Gene

No ASD Table

Relevant External Links for SOWAHB Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SOWAHB Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SOWAHB Gene

mRNA differential expression in normal tissues according to GTEx for SOWAHB Gene

This gene is overexpressed in Liver (x6.3), Esophagus - Mucosa (x5.4), Brain - Frontal Cortex (BA9) (x5.0), Brain - Cortex (x5.0), and Colon - Transverse (x4.1).

Protein differential expression in normal tissues from HIPED for SOWAHB Gene

This gene is overexpressed in Pancreas (39.6), Heart (14.9), and Adipocyte (8.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SOWAHB Gene

Protein tissue co-expression partners for SOWAHB Gene

NURSA nuclear receptor signaling pathways regulating expression of SOWAHB Gene:


SOURCE GeneReport for Unigene cluster for SOWAHB Gene:

genes like me logo Genes that share expression patterns with SOWAHB: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for SOWAHB Gene

Orthologs for SOWAHB Gene

This gene was present in the common ancestor of animals.

Orthologs for SOWAHB Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SOWAHB 34
  • 98.23 (n)
(Canis familiaris)
Mammalia SOWAHB 34 35
  • 80.15 (n)
(Bos Taurus)
Mammalia SOWAHB 34 35
  • 79.49 (n)
(Rattus norvegicus)
Mammalia Sowahb 34
  • 77.67 (n)
(Mus musculus)
Mammalia Sowahb 34 16 35
  • 77.29 (n)
(Monodelphis domestica)
Mammalia SOWAHB 35
  • 55 (a)
(Gallus gallus)
Aves SOWAHB 34 35
  • 61.25 (n)
(Anolis carolinensis)
Reptilia SOWAHB 35
  • 33 (a)
(Danio rerio)
Actinopterygii CR381544.1 35
  • 22 (a)
wufa55b05 34
fruit fly
(Drosophila melanogaster)
Insecta sowah 35
  • 11 (a)
Species where no ortholog for SOWAHB was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SOWAHB Gene

Gene Tree for SOWAHB (if available)
Gene Tree for SOWAHB (if available)

Paralogs for SOWAHB Gene

Paralogs for SOWAHB Gene

genes like me logo Genes that share paralogs with SOWAHB: view

Variants for SOWAHB Gene

Sequence variations from dbSNP and Humsavar for SOWAHB Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs111454593 -- 76,896,266(+) CTGGA(C/T)CGAGG upstream-variant-2KB, reference, synonymous-codon
rs111467942 -- 76,898,383(+) GACCG(C/G)CCGTT intron-variant, upstream-variant-2KB
rs111761010 -- 76,895,474(+) CAGTC(A/G)CTATA reference, synonymous-codon
rs111983072 -- 76,898,794(+) GCTGG(-/A)AAAAA intron-variant, upstream-variant-2KB
rs112402456 -- 76,896,953(+) GCTGC(-/TGC)AGGGT upstream-variant-2KB, cds-indel

Structural Variations from Database of Genomic Variants (DGV) for SOWAHB Gene

Variant ID Type Subtype PubMed ID
nsv7363 OTHER inversion 18451855
nsv829973 CNV loss 17160897

Variation tolerance for SOWAHB Gene

Residual Variation Intolerance Score: 52.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 10.04; 90.09% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SOWAHB Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SOWAHB Gene

Disorders for SOWAHB Gene

Relevant External Links for SOWAHB

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SOWAHB Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SOWAHB Gene

Publications for SOWAHB Gene

  1. An ancient genomic regulatory block conserved across bilaterians and its dismantling in tetrapods by retrogene replacement. (PMID: 22234889) Maeso I. … Garcia-FernA ndez J. (Genome Res. 2012) 2 3 64
  2. An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y. … Zou H. (J. Proteomics 2014) 4 64
  3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for SOWAHB Gene

Sources for SOWAHB Gene

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