Aliases for SORCS1 Gene
Aliases for SORCS1 Gene
External Ids for SORCS1 Gene
- HGNC: 16697
- Entrez Gene: 114815
- Ensembl: ENSG00000108018
- OMIM: 606283
- UniProtKB: Q8WY21
Previous GeneCards Identifiers for SORCS1 Gene
- GC10M107226
- GC10M107567
- GC10M108464
- GC10M107998
- GC10M108323
- GC10M101965
Summaries for SORCS1 Gene
-
This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins; it is not yet known if this encoded protein is also a preproprotein. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for SORCS1 Gene
SORCS1 (Sortilin Related VPS10 Domain Containing Receptor 1) is a Protein Coding gene. Diseases associated with SORCS1 include Narcolepsy. Among its related pathways are Ectoderm Differentiation. Gene Ontology (GO) annotations related to this gene include neuropeptide receptor activity. An important paralog of this gene is SORCS3.
Additional gene information for SORCS1 Gene
- Monarch Initiative
- Search for SORCS1 at DataMed
- Search for SORCS1 at HumanCyc
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SORCS1 Gene
Genomics for SORCS1 Gene
GeneHancer (GH) Regulatory Elements for SORCS1 Gene
Promoters and enhancers for SORCS1 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH10I107164 | Promoter/Enhancer | 1.5 | EPDnew Ensembl ENCODE | 550.4 | +16.3 | 16330 | 0.4 | ZNF335 MXI1 ZBTB26 ZXDB EZH2 | SORCS1 GC10M106873 | |
| GH10I107054 | Enhancer | 0.7 | ENCODE | 7.4 | +125.0 | 125036 | 2.4 | TEAD4 TAL1 MAX RAD21 YY1 TCF12 NCOR1 HNF4G CBFA2T2 CREM | SORCS1 GC10M106873 RNA5SP325 | |
| GH10I107031 | Enhancer | 0.8 | ENCODE | 5.1 | +148.6 | 148638 | 1.7 | HDAC1 PKNOX1 TAF9B NFRKB CHAMP1 POLR2B RCOR1 ATF7 NCOA1 ZNF148 | SORCS1 GC10M106873 RNA5SP325 | |
| GH10I107215 | Enhancer | 0.2 | ENCODE | 11.3 | -34.7 | -34712 | 0.2 | SORCS1 GC10M107296 | ||
| GH10I107216 | Enhancer | 0.2 | ENCODE | 11.3 | -34.4 | -34432 | 0.2 | SORCS1 GC10M107296 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around SORCS1 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the SORCS1 gene promoter:
Regulatory Element Products
Genomic Locations for SORCS1 Gene
Genomic Locations for SORCS1 Gene
- chr10:106,573,663-107,181,126
- (GRCh38/hg38)
- Size:
- 607,464 bases
- Orientation:
- Minus strand
- chr10:108,333,421-108,924,466
- (GRCh37/hg19)
Genomic View for SORCS1 Gene
Genes around SORCS1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 10q25.1 by Ensembl
- 10q25.1 by Entrez Gene
- 10q25.1 by HGNC
SORCS1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SORCS1 Gene
Proteins for SORCS1 Gene
-
Protein details for SORCS1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8WY21-SORC1_HUMAN
- Recommended name:
- VPS10 domain-containing receptor SorCS1
- Protein Accession:
- Q8WY21
- A2RRF4
- Q59GG7
- Q5JVT7
- Q5JVT8
- Q5VY14
- Q86WQ1
- Q86WQ2
- Q9H1Y1
- Q9H1Y2
Protein attributes for SORCS1 Gene
- Size:
- 1168 amino acids
- Molecular mass:
- 129635 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAD92379.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=CAI40754.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI40755.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Protein Expression for SORCS1 Gene
Post-translational modifications for SORCS1 Gene
- O-glycosylated.
- Glycosylation at isoforms=2, 3, 468, isoforms=2, 3, 4184, isoforms=2, 3, 4352, posLast=433433, isoforms=2, 3, 4765, posLast=776776, isoforms=2, 3, 4816, isoforms=2, 3, 4847, posLast=908908, and isoforms=2, 3, 4929
Other Protein References for SORCS1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
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Protein Products
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-
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Quality Products:
No data available for DME Specific Peptides for SORCS1 Gene
Domains & Families for SORCS1 Gene
Gene Families for SORCS1 Gene
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
Protein Domains for SORCS1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for SORCS1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q8WY21- Family:
-
- Belongs to the VPS10-related sortilin family. SORCS subfamily.
Function for SORCS1 Gene
Phenotypes From GWAS Catalog for SORCS1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 12482870 |
| GO:0008188 | neuropeptide receptor activity | NAS | 11499680 |
Phenotypes for SORCS1 Gene
- MGI mutant phenotypes for SORCS1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for SORCS1:
Animal Model Products
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-
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Vectors and viruses for KO, Activation, Repression, and more
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miRNA for SORCS1 Gene
- miRTarBase miRNAs that target SORCS1
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Clone Products
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-
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
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- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
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-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
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Horizon Cell Lines for SORCS1
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SORCS1 Gene
Localization for SORCS1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SORCS1 Gene
- Membrane; Single-pass type I membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 4 |
| cytosol | 2 |
| golgi apparatus | 2 |
| endosome | 2 |
- Cytosol (2)
- Plasma membrane (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016020 | membrane | IDA,IEA | 12482870 |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for SORCS1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Ectoderm Differentiation | ||
Pathways by source for SORCS1 Gene
1 BioSystems pathway for SORCS1 Gene
Interacting Proteins for SORCS1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007218 | neuropeptide signaling pathway | NAS | 11499680 |
No data available for SIGNOR curated interactions for SORCS1 Gene
Transcripts for SORCS1 Gene
mRNA/cDNA for SORCS1 Gene
- (13) REFSEQ mRNAs :
- (12) Additional mRNA sequences :
- (55) Selected AceView cDNA sequences:
- (10) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for SORCS1 Gene
- Sortilin-related VPS10 domain containing receptor 1:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for SORCS1
- genomics-online: gRNA clones - Search results for 98 available SORCS1 gene related products
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-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for SORCS1
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miRNA Products
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Inhibitory RNA Products
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Clone Products
-
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for SORCS1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: |
| ExUns: | 25 | ^ | 26 | ^ | 27 | ^ | 28 |
|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||
| SP2: | - | ||||||
| SP3: | |||||||
| SP4: |
Expression for SORCS1 Gene
mRNA differential expression in normal tissues according to GTEx for SORCS1 Gene
This gene is overexpressed in Nerve - Tibial (x9.0) and Brain - Nucleus accumbens (basal ganglia) (x4.1).
This gene is overexpressed in Colon (15.7), Fetal gut (14.4), and Rectum (12.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for SORCS1 Gene
NURSA nuclear receptor signaling pathways regulating expression of SORCS1 Gene:
SORCS1SOURCE GeneReport for Unigene cluster for SORCS1 Gene:
Hs.591915mRNA Expression by UniProt/SwissProt for SORCS1 Gene:
Q8WY21-SORC1_HUMAN
Tissue specificity:
Detected in fetal and infant brain and in fetal retina.
Evidence on tissue expression from TISSUES for SORCS1 Gene
- Nervous system(4.6)
Primer Products
-
OriGene qPCR primer pairs for SORCS1
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for SORCS1 Gene
Orthologs for SORCS1 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | SORCS1 34 33 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | SORCS1 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | SORCS1 33 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | SORCS1 34 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | SORCS1 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Sorcs1 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Sorcs1 33 |
|
||
| chicken (Gallus gallus) |
Aves | SORCS1 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
OneToMany | |
| -- 34 |
|
OneToMany | |||
| zebrafish (Danio rerio) |
Actinopterygii | SORCS1 34 |
|
OneToOne | |
| sorcs1 33 |
|
||||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | -- 34 |
|
ManyToMany | |
| -- 34 |
|
ManyToMany | |||
| -- 34 |
|
ManyToMany | |||
| -- 34 |
|
ManyToMany | |||
| PEP1 34 |
|
ManyToMany | |||
| -- 34 |
|
ManyToMany | |||
| VTH1 34 |
|
ManyToMany | |||
| VTH2 34 |
|
ManyToMany | |||
| -- 36 |
|
|
|||
| -- 36 |
|
|
|||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany |
- Species where no ortholog for SORCS1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for SORCS1 Gene
(2) SIMAP similar genes for SORCS1 Gene using alignment to 5 proteins:
Variants for SORCS1 Gene
| SNP ID | Clin | Chr 10 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs193920991 | uncertain-significance, Malignant tumor of prostate | 106,579,243(-) | G/A/T | 3_prime_UTR_variant, coding_sequence_variant, genic_downstream_transcript_variant, intron_variant, missense_variant | |
| VAR_036374 | A breast cancer sample | p.Lys223Asn | |||
| rs1000003405 | -- | 106,680,915(-) | T/A | intron_variant | |
| rs1000010749 | -- | 106,703,644(-) | G/T | genic_upstream_transcript_variant, intron_variant | |
| rs1000014009 | -- | 106,997,290(-) | G/T | genic_upstream_transcript_variant, intron_variant |
Residual Variation Intolerance Score:
19.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.97;
59.89% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SORCS1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SORCS1 Gene
Disorders for SORCS1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| narcolepsy |
|
|
Search SORCS1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for SORCS1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for SORCS1 Gene
Publications for SORCS1 Gene
- Characterization of sorCS1, an alternatively spliced receptor with completely different cytoplasmic domains that mediate different trafficking in cells. (PMID: 12482870) Hermey G … Gliemann J (The Journal of biological chemistry 2003) 3 4 22 58
- The genes for the human VPS10 domain-containing receptors are large and contain many small exons. (PMID: 11499680) Hampe W … Schaller HC (Human genetics 2001) 2 3 4 58
- A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both A1C and glucose. (PMID: 19875614) Paterson AD … Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group (Diabetes 2010) 3 44 58
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
- Systematic analysis of candidate genes for Alzheimer's disease in a French, genome-wide association study. (PMID: 20413850) Laumet G … Lambert JC (Journal of Alzheimer's disease : JAD 2010) 3 44 58
Products for SORCS1 Gene
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 37 available SORCS1 Antibodies ranked by validation data
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- genomics-online: gRNA clones - Search results for 98 available SORCS1 gene related products
- Overview of 98 available SORCS1 gene related products
- genomics-online: primer clones - Search results for 98 available SORCS1 gene related products
- Overview of 98 available SORCS1 gene related products
- genomics-online: shRNA clones - Search results for 98 available SORCS1 gene related products
- Overview of 98 available SORCS1 gene related products
Sources for SORCS1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew