Aliases for SORCS1 Gene
External Ids for SORCS1 Gene
Previous GeneCards Identifiers for SORCS1 Gene
This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins; it is not yet known if this encoded protein is also a preproprotein. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for SORCS1 Gene
SORCS1 (Sortilin-Related VPS10 Domain Containing Receptor 1) is a Protein Coding gene. GO annotations related to this gene include neuropeptide receptor activity. An important paralog of this gene is SORCS2.