SORBS3 Gene
protein-coding GIFtS: 54
GCID: GC08P022409
|
|
sorbin and SH3 domain containing 3
| |
Aliases
for SORBS3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Sorbin And SH3 Domain Containing 31 2 | | Vinexin1 | | SCAM-11 2 3 | | Sorbin And SH3 Domain-Containing Protein 32 3 | | SH3D41 2 5 | | Vinexin Beta (SH3-Containing Adaptor Molecule-1)2 | | SCAM12 3 5 | | SH3-Containing Adapter Molecule 13 |
Export aliases for SORBS3 gene to outside databasesPrevious GC identifers: GC08P022466 GC08P020951 |
Summaries
for SORBS3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SORBS3:
This gene encodes an SH3 domain-containing adaptor protein. The presence of SH3 domains play a role in this protein'sability to bind other cytoplasmic molecules and contribute to cystoskeletal organization, cell adhesion and migration,signaling, and gene expression. Multiple transcript variants encoding different isoforms have been found for thisgene. (provided by RefSeq, Nov 2011)
UniProtKB/Swiss-Prot: VINEX_HUMAN, O60504Function: Vinexin alpha isoform promotes up-regulation of actin stress fiber formation. Vinexin beta isoform plays arole in cell spreading and enhances the activation of JNK/SAPK in response to EGF stimulation by using its third SH3domain
Gene Wiki entry for SORBS3
|
Genomic Views
for SORBS3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_167187.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SORBS3 gene promoter:
E2F-4 E2F-3a E2F-5 E2F-1 E2F E2F-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for SORBS3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SORBS3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8p21.3 Ensembl cytogenetic band: 8p21.3 HGNC cytogenetic band: 8p21.3SORBS3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08P022409: view genomic region
(about GC identifiers)
Start:
|
22,402,499 bp from pter |
End:
|
22,433,301 bp from pter |
Size:
|
30,803 bases |
Orientation:
|
plus strand |
|
Proteins
for SORBS3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: VINEX_HUMAN, O60504 (See
protein sequence)Recommended Name: Vinexin Size: 671 amino acids; 75341 Da
Subunit: Interacts with DLG5 through its third SH3 domain (By similarity). Interacts with vinculin by the first two SH3domains and the proline rich region of vinculin. Binds to SOS (guanine nucleotide exchange factor of RAS and RAC),through its third SH3 domain. The formation of this complex is down-regulated by phosphorylation of SOS. Interactswith INPPL1/SHIP2, SAFB2, SOCS7 and SRCIN1. Interacts with FASLG. Interacts with MAPK1/ERK2 (By similarity)
Subcellular location: Isoform Alpha: Cell junction (By similarity). Cytoplasm, cytoskeleton (By similarity).Note=Localized at cell-extracellular matrix junctions (By similarity). Both isoforms were localized at focal adhesionand cell-cell adhesion sites
Subcellular location: Isoform Beta: Cell junction (By similarity). Nucleus. Cytoplasm, cytoskeleton (By similarity).Note=Localized at cell-extracellular matrix junctions (By similarity). Both isoforms were localized at focal adhesionand cell-cell adhesion sites, vinexin beta was also found in the nucleus
4 PDB 3D structures from  and Proteopedia  for SORBS3:2CT3 (3D)
2DLM (3D)
2NWM (3D)
2YUP (3D)
Secondary accessions: Q5BJE4 Q6NX54 Q96FY4 Q9UQE4Alternative splicing: 2 isoforms: O60504-1 O60504-2 Explore the universe of human proteins at neXtProt for SORBS3: NX_O60504
Post-translational modifications:
Phosphorylated at Ser-530 by MAPK1/ERK2 during cell spreading (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O60504
SORBS3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001018003.1 NP_005766.3
ENSEMBL proteins: ENSP00000240123 ENSP00000429723 ENSP00000429685 ENSP00000428102 ENSP00000428051 ENSP00000431128 ENSP00000429887 ENSP00000429764 ENSP00000429058 ENSP00000429479 ENSP00000428678 ENSP00000428327 ENSP00000429747 ENSP00000428930 ENSP00000408476 Reactome Protein details: O60504
Human Recombinant Protein Products for SORBS3:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
SORBS3 for ontologies About GeneDecksing
SORBS3 Antibody Products:
Assay Products for SORBS3: |
Protein
Domains /
Families
for SORBS3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SORBS3 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O60504ProtoNet protein and cluster: O60504 1 Blocks protein family: IPB003127 Sorbin-like
UniProtKB/Swiss-Prot: VINEX_HUMAN, O60504Similarity: Contains 3 SH3 domainsSimilarity: Contains 1 SoHo domain |
Function
for SORBS3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: VINEX_HUMAN, O60504Function: Vinexin alpha isoform promotes up-regulation of actin stress fiber formation. Vinexin beta isoform plays arole in cell spreading and enhances the activation of JNK/SAPK in response to EGF stimulation by using its third SH3domain Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
SORBS3 for ontologies About GeneDecksing
Phenotypes:
3 GenomeRNAi human phenotypes for SORBS3:
3 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Sorbs3):
SORBS3 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-outs for SORBS3: Sorbs3tm1Kmor Sorbs3tm1Kiok
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SORBS3 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SORBS3 (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): SORBS3 (NM_005775) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SORBS3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SORBS3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SORBS3 |
|
Pathways & Interactions
for SORBS3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Striated Muscle Contraction | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for SORBS3
SORBS3 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SORBS3
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/63 Interacting proteins for SORBS3 (O605041, 2, 3 ENSP000002401234) via UniProtKB, MINT, STRING, and/or I2D (see all 63)About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table
SORBS3 for ontologies About GeneDecksing
|
Drugs & Compounds
for SORBS3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SORBS3
3 HMDB Compounds for SORBS3 About this table
Search CenterWatch for drugs/clinical trials and news about SORBS3 / VINEX
|
Transcripts
for SORBS3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SORBS3 gene (2 alternative transcripts): NM_001018003.2 NM_005775.4 Unigene Cluster for SORBS3: Sorbin and SH3 domain containing 3 Hs.528572 [show with all ESTs]Unigene Representative Sequence: BC09151418/24 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 24): ENST00000522037 ENST00000523941 ENST00000240123(uc011kzk.1 uc003xbv.3)
ENST00000517500 ENST00000517535 ENST00000523402 ENST00000520563 ENST00000524057
ENST00000518512 ENST00000520574 ENST00000521787 ENST00000523740 ENST00000522315
ENST00000519453 ENST00000523900 ENST00000518912 ENST00000523965 ENST00000521554
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SORBS3 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SORBS3 (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): SORBS3 (NM_005775) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SORBS3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SORBS3 |
Additional cDNA sequence: AF037261.1 AF064807.1 AK303950.1 BC004314.1 BC010146.2 BC067260.1 BC091514.1 24/29 DOTS entries (see all 29): DT.92433783 DT.100038429 DT.100828958 DT.120628482 DT.91926199 DT.92433786 DT.100729185 DT.120628411 DT.120628518 DT.75103734 DT.100828971 DT.100828978 DT.120628451 DT.120628525 DT.92433787 DT.95140503 DT.100772845 DT.100828959 DT.100828964 DT.100828965 DT.100828973 DT.120628449 DT.40202046 DT.92433776 24/306 AceView cDNA sequences (see all 306): BI820254 BE550698 BM762330 CR622445 BQ005326 BG419471 BM695393 BQ941725 CR605936 BF515469 BG763775 CR621670 AL041129 BU071310 BF221857 CR606865 BF447251 BM665038 BU543651 BM724959 BQ641600 AA294821 BF438188 BE707490
GeneLoc Exon Structure
5/24 Alternative Splicing Database (ASD) splice patterns (SP) for SORBS3 (see all 24) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | 13b | ^ | 14a | · | 14b | · | 14c | ^ | 15a | · | 15b | · |
|---|
|
| SP1: | | | | | | | | | - | | | | | | | | - | | | | - | | - | | | | | | | | | | | | - | | - | | - | | - | | | | | | - | | - | | - | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | - | | - | | - | | - | | | | | | - | | - | | - | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 15c | · | 15d | · | 15e | · | 15f | ^ | 16a | · | 16b | · | 16c | ^ | 17a | · | 17b | · | 17c | ^ | 18 | ^ | 19a | · | 19b | ^ | 20a | · | 20b | · | 20c | ^ | 21a | · | 21b | · | 21c | ^ | 22a | · | 22b | · | 22c | · | 22d | · | 22e | · | 22f | · | 22g | ^ |
|---|
|
| SP1: | - | | - | | - | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | - | | - | | - | | | | - | | - | | - | | - | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 23a | · | 23b | ^ | 24 | ^ | 25a | · | 25b | · | 25c | ^ | 26a | · | 26b |
|---|
|
| SP1: | - | | | | | | | | | | | | | | | | |
| SP2: | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | |
| SP5: | - | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SORBS3
|
Expression
for SORBS3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SORBS3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCAACTTGGA
About this image
See SORBS3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SORBS3
SOURCE GeneReport for Unigene cluster: Hs.528572
UniProtKB/Swiss-Prot: VINEX_HUMAN, O60504Tissue specificity: Both isoforms are expressed in different tissues like heart, placenta, brain, skeletal muscle andpancreas. Isoform beta is especially found in liver
SABiosciences Custom PCR Arrays for SORBS3
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SORBS3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SORBS3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SORBS3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SORBS3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SORBS3 |
Orthologs
for SORBS3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SORBS3 gene from 4/14 species (see all 14) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
SORBS36 |
-- |
68(a) |
1 ↔ 1 |
GL343443.1(394065-411678) |
zebrafish
(Danio rerio) |
Actinopterygii |
sorbs31 |
sorbin and SH3 domain containing 3 |
52.09(n)
48.58(a) |
|
541478 NM_001014290.1 NP_001014312.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CAP6 |
CAP |
5(a) |
1 → many |
2R(6156528-6194529) |
worm
(Caenorhabditis elegans) |
Secernentea |
sorb-16 |
Temporarily Assigned Gene name family member (tag-... |
12(a) |
1 → many |
IV(13750312-13770583) |
ENSEMBL Gene Tree for SORBS3 (if available)
TreeFam Gene Tree for SORBS3 (if available) |
Paralogs
for SORBS3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SORBS3 gene
- SH3RF32 SH3RF22 SH3RF12 SORBS12 SORBS22 SH3D192
18/19 SIMAP similar genes for SORBS3 using alignment to 15 protein entries: VINEX_HUMAN (see all proteins)
(see all similar genes):ARHGAP4 GRB2 VAV3 VAV1 SH3GL2 DOCK2
SH3RF3 ARHGEF7 SORBS1 SORBS2 ITSN1 NOSTRIN
GRAP2 ITSN2 DKFZp686N08224 STAM ABI1 SH3GL1
SORBS3 for paralogs About GeneDecksing
|
Genomic Variants
for SORBS3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 8 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SORBS3 (22402499 - 22433301 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for SORBS3
2 CNVs: 2746 3726 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SORBS3 |
|
Disorders
/ Diseases
for SORBS3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SORBS3 for disorders About GeneDecksing
OMIM gene information: 610795
OMIM disorders: --
2  diseases for SORBS3: About MalaCardshepatocellular carcinoma carcinoma
Export disorders for SORBS3 gene to outside databases
|
Publications
for SORBS3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SORBS3 gene, integrated from 9 sources (see all 51):
(articles sorted by number of sources associating them with SORBS3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Vinexin: a novel vinculin-binding protein with multiple SH3 domains enhances actin cytoskeletal organization. (PubMed id 9885244)1, 2, 3 Kioka N.... Aota S. (1999)
- Vinexin forms a signaling complex with Sos and modulates epidermal growth factor-induced c-Jun N-terminal kinase/stress-activated protein kinase activities. (PubMed id 10585480)1, 2, 9 Akamatsu M.... Kioka N. (1999)
- The suppressor of cytokine signaling (SOCS)-7 interacts with the actin cytoskeleton through vinexin. (PubMed id 15242778)1, 2, 9 Martens N.... Hooghe-Peters E.L. (2004)
- SAFB2, a new scaffold attachment factor homolog and estrogen receptor corepressor. (PubMed id 12660241)1, 2, 9 Townson S.M.... Oesterreich S. (2003)
- Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening. (PubMed id 19807924)1, 2 Voss M....Janssen O. (2009)
- Characterization of a multidomain adaptor protein, p1 40Cap, as part of a pre-synaptic complex. (PubMed id 18662323)1, 2 Ito H....Nagata K. (2008)
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- SHIP2 interaction with the cytoskeletal protein Vinexin. (PubMed id 16302969)1, 2 Paternotte N.... Erneux C. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
|
External Searches for SORBS3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SORBS3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing SORBS3 gene
(According to HUGE)
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Specialized Databases showing SORBS3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for SORBS3 | Pharmacogenomics, SNPs, Pathways |
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| Patent Information for SORBS3 gene:
Search GeneIP for patents involving SORBS3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for SORBS3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SORBS3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SORBS3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SORBS3 | | | OriGene Protein Over-expression Lysate for SORBS3 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SORBS3 | | OriGene 3'-UTR Clone for SORBS3 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SORBS3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SORBS3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SORBS3 | | OriGene Custom Protein Services for SORBS3 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SORBS3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SORBS3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SORBS3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SORBS3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SORBS3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SORBS3 |
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| | | | Search Tocris compounds for SORBS3 |
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 | | | SORBS3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SORBS3 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for SORBS3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SORBS3 |
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