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Aliases for SOGA3 Gene

Aliases for SOGA3 Gene

  • SOGA Family Member 3 2 3
  • C6orf174 3 4
  • Chromosome 6 Open Reading Frame 174 2
  • Protein SOGA3 3
  • DJ403A15.3 3

External Ids for SOGA3 Gene

Previous HGNC Symbols for SOGA3 Gene

  • C6orf174

Previous GeneCards Identifiers for SOGA3 Gene

  • GC06M127760

Summaries for SOGA3 Gene

GeneCards Summary for SOGA3 Gene

SOGA3 (SOGA Family Member 3) is a Protein Coding gene. An important paralog of this gene is SOGA1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SOGA3 Gene

Genomics for SOGA3 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SOGA3 Gene

Start:
127,438,406 bp from pter
End:
127,519,355 bp from pter
Size:
80,950 bases
Orientation:
Minus strand

Genomic View for SOGA3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SOGA3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SOGA3 Gene

No data available for Regulatory Elements for SOGA3 Gene

Proteins for SOGA3 Gene

  • Protein details for SOGA3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5TF21-SOGA3_HUMAN
    Recommended name:
    Protein SOGA3
    Protein Accession:
    Q5TF21
    Secondary Accessions:

    Protein attributes for SOGA3 Gene

    Size:
    947 amino acids
    Molecular mass:
    103199 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SOGA3 Gene

Proteomics data for SOGA3 Gene at MOPED

Post-translational modifications for SOGA3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SOGA3 Gene

No data available for DME Specific Peptides for SOGA3 Gene

Domains for SOGA3 Gene

Protein Domains for SOGA3 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q5TF21

UniProtKB/Swiss-Prot:

SOGA3_HUMAN :
  • Q5TF21
Family:
  • Belongs to the SOGA family.
genes like me logo Genes that share domains with SOGA3: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for SOGA3 Gene

Function for SOGA3 Gene

Animal Model Products

miRNA for SOGA3 Gene

miRTarBase miRNAs that target SOGA3

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SOGA3

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for SOGA3 Gene

Localization for SOGA3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SOGA3 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SOGA3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SOGA3: view

No data available for Subcellular locations from COMPARTMENTS for SOGA3 Gene

Pathways for SOGA3 Gene

SuperPathways for SOGA3 Gene

No Data Available

Interacting Proteins for SOGA3 Gene

Gene Ontology (GO) - Biological Process for SOGA3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0010506 regulation of autophagy IEA --
genes like me logo Genes that share ontologies with SOGA3: view

No data available for Pathways by source for SOGA3 Gene

Transcripts for SOGA3 Gene

mRNA/cDNA for SOGA3 Gene

(11) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SOGA3 Gene

SOGA family member 3:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SOGA3

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SOGA3 Gene

No ASD Table

Relevant External Links for SOGA3 Gene

GeneLoc Exon Structure for
SOGA3
ECgene alternative splicing isoforms for
SOGA3

Expression for SOGA3 Gene

mRNA expression in normal human tissues for SOGA3 Gene

Protein differential expression in normal tissues for SOGA3 Gene

This gene is overexpressed in Breast (25.4), Fetal Brain (15.4), Frontal cortex (13.0), and Liver, secretome (7.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for SOGA3 Gene

SOURCE GeneReport for Unigene cluster for SOGA3 Gene Hs.319247

genes like me logo Genes that share expressions with SOGA3: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Expression partners for SOGA3 Gene

Orthologs for SOGA3 Gene

This gene was present in the common ancestor of animals.

Orthologs for SOGA3 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia SOGA3 35
  • 92.06 (n)
  • 93.96 (a)
-- 36
  • 93 (a)
OneToMany
dog
(Canis familiaris)
Mammalia SOGA3 35
  • 90.63 (n)
  • 92.01 (a)
-- 36
  • 89 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Soga3 35
  • 87.76 (n)
  • 89.84 (a)
Soga3 36
  • 91 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia SOGA3 35
  • 99.33 (n)
  • 99.47 (a)
-- 36
  • 99 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia LOC100363248 35
  • 87.92 (n)
  • 89.83 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 74 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 76 (a)
OneToMany
chicken
(Gallus gallus)
Aves C3H6ORF174 35
  • 80.96 (n)
  • 95.25 (a)
-- 36
  • 86 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 88 (a)
ManyToMany
-- 36
  • 80 (a)
ManyToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia soga3 35
  • 76.5 (n)
  • 90.85 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC100332515 35
  • 74.04 (n)
  • 81.8 (a)
soga3a 36
  • 64 (a)
ManyToMany
soga3b 36
  • 61 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta CG18304 36
  • 8 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea tag-241 36
  • 7 (a)
OneToMany
Species with no ortholog for SOGA3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SOGA3 Gene

ENSEMBL:
Gene Tree for SOGA3 (if available)
TreeFam:
Gene Tree for SOGA3 (if available)

Paralogs for SOGA3 Gene

Paralogs for SOGA3 Gene

Selected SIMAP similar genes for SOGA3 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with SOGA3: view

Variants for SOGA3 Gene

Sequence variations from dbSNP and Humsavar for SOGA3 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs500749 -- 127,510,485(-) AGAAC(A/G)ATGGG intron-variant
rs514064 -- 127,487,910(-) aattg(G/T)tctgg intron-variant
rs519094 -- 127,507,330(-) CACCC(C/T)CATGT intron-variant
rs528954 -- 127,511,255(-) AAAAA(A/G)ATGTA intron-variant
rs534530 -- 127,511,867(-) ATATA(A/G)TGCAA intron-variant

Relevant External Links for SOGA3 Gene

HapMap Linkage Disequilibrium report
SOGA3
Human Gene Mutation Database (HGMD)
SOGA3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SOGA3 Gene

Disorders for SOGA3 Gene

No disorders were found for SOGA3 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for SOGA3 Gene

Publications for SOGA3 Gene

  1. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. Complementary quantitative proteomics reveals that transcription factor AP-4 mediates E-box-dependent complex formation for transcriptional repression of HDM2. (PMID: 19505873) Ku W.C. … Chen Y.J. (Mol. Cell Proteomics 2009) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for SOGA3 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate SOGA3
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for SOGA3
    • Block miRNA regulation of SOGA3 using miScript Target Protectors

    Sources for SOGA3 Gene

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