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SOGA1 Gene

protein-coding   GIFtS: 43
GCID: GC20M035407

Suppressor Of Glucose, Autophagy Associated 1

(Previous names: chromosome 20 open reading frame 117, KIAA0889)
(Previous symbols: C20orf117, KIAA0889)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Suppressor Of Glucose, Autophagy Associated 11 2     Suppressor Of Glucose, Autophagy-Associated Protein 12 3
C20orf1171 2 3     SOGA2 3
KIAA08891 2 3     SOGA Family Member 12 3
Suppressor Of Glucose By Autophagy1 2 3     Chromosome 20 Open Reading Frame 1171
Suppressor Of Glucose From Autophagy1 2     Protein SOGA12

External Ids:    HGNC: 161111   Entrez Gene: 1407102   Ensembl: ENSG000001496397   UniProtKB: O949643   

Export aliases for SOGA1 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SOGA1 Gene:
SOGA1 (suppressor of glucose, autophagy associated 1) is a protein-coding gene. An important paralog of this gene is MTCL1.

UniProtKB/Swiss-Prot: SOGA1_HUMAN, O94964
Function: Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and
insulin-dependent manner (By similarity)

Gene Wiki entry for SOGA1 (C20orf117) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000020.11  NC_018931.2  NT_011362.11  
Regulatory elements:
   Search for regulatory transcription factor binding sites for SOGA1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSOGA1 promoter sequence
   Search Chromatin IP Primers for SOGA1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SOGA1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q11.23   Ensembl cytogenetic band:  20q11.23   HGNC cytogenetic band: 20q11.23

SOGA1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SOGA1 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M035407:  view genomic region     (about GC identifiers)

Start:
35,405,845 bp from pter      End:
35,492,089 bp from pter
Size:
86,245 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: SOGA1_HUMAN, O94964 (See protein sequence)
Recommended Name: Protein SOGA1  
Size: 1423 amino acids; 159760 Da
Subunit: The C-terminal 25 kDa form occurs as a monomer (By similarity)
Sequence caution: Sequence=BAA74912.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A6NK10 Q14DB2 Q5JW51 Q6ZTG8
Alternative splicing: 4 isoforms:  O94964-1   O94964-2   O94964-3   O94964-4   (No experimental confirmation available. Gene prediction based on EST data)

Explore the universe of human proteins at neXtProt for SOGA1: NX_O94964

Explore proteomics data for SOGA1 at MOPED

Post-translational modifications: 

  • Proteolytically cleaved in primary hepatocytes into a C-terminal 80 kDa form (By similarity). Proteolytically
    cleaved into a C-terminal SOGA 25 kDa form that is detected in plasma1
  • Ubiquitination2 at Lys809, Lys867, Lys878, Lys886
  • Modification sites at PhosphoSitePlus

  • See SOGA1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_542194.2  NP_954650.2  

    ENSEMBL proteins: 
     ENSP00000237536   ENSP00000279034   ENSP00000433939   ENSP00000350424   ENSP00000413886  

    SOGA1 Human Recombinant Protein Products:

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    Novus Biologicals SOGA1 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

    SOGA1 Antibody Products:

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    LSBio Antibodies in human, mouse, rat for SOGA1

    SOGA1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR027881 SOGA
     IPR027882 DUF4482

    Graphical View of Domain Structure for InterPro Entry O94964

    ProtoNet protein and cluster: O94964

    UniProtKB/Swiss-Prot: SOGA1_HUMAN, O94964
    Similarity: Belongs to the SOGA family


    SOGA1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SOGA1_HUMAN, O94964
    Function: Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and
    insulin-dependent manner (By similarity)
    Induction: Up-regulated in the plasma by adiponectin in healthy fasting female

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    SOGA1 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for SOGA1:
     Increased 8N DNA content  Increased gamma-H2AX phosphory  Increased number of mitotic ce 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SOGA1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SOGA1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SOGA1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SOGA1

    miRNA
    Products:
        
    miRTarBase miRNAs that target SOGA1:
    hsa-mir-22-3p (MIRT030652), hsa-mir-100-5p (MIRT048567), hsa-mir-19b-3p (MIRT031173), hsa-mir-92b-3p (MIRT040613)

    Block miRNA regulation of human, mouse, rat SOGA1 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate SOGA1
    SwitchGear 3'UTR luciferase reporter plasmidSOGA1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SOGA1
    Predesigned siRNA for gene silencing in human, mouse, rat SOGA1

    Gene Editing
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    Clone
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    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SOGA1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SOGA1

    Cell Line
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SOGA1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SOGA1_HUMAN, O94964: C-terminal 80 kDa form: Secreted (By similarity). Note=Secreted in primary
    hepatocyte-conditioned media (By similarity)

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IDA--
    GO:0070062extracellular vesicular exosome IDA19056867

    SOGA1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SOGA1
    Interactions:

        Search GeneGlobe Interaction Network for SOGA1

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    Selected Interacting proteins for SOGA1 (O949643 ENSP000002790344) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MARK4Q96L343, ENSP000003008434I2D: score=2 STRING: ENSP00000300843
    PLEKHA5Q9HAU03, ENSP000002992754I2D: score=2 STRING: ENSP00000299275
    STAT1P422243I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    SIRT7ENSP000003294664STRING: ENSP00000329466
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008286insulin receptor signaling pathway ISS--
    GO:0010506regulation of autophagy ISS--
    GO:0045721negative regulation of gluconeogenesis ISS--

    SOGA1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SOGA1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SOGA1 gene (3 alternative transcripts): 
    NM_152257.1  NM_080627.2  NM_199181.2  

    Unigene Cluster for SOGA1:

    Suppressor of glucose, autophagy associated 1
    Hs.460807  [show with all ESTs]
    Unigene Representative Sequence: NM_080627
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000237536(uc021wcx.1) ENST00000279034(uc002xgd.1) ENST00000465671
    ENST00000463491 ENST00000357779 ENST00000456801
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SOGA1 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate SOGA1
    SwitchGear 3'UTR luciferase reporter plasmidSOGA1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SOGA1
    Predesigned siRNA for gene silencing in human, mouse, rat SOGA1
    Clone
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    OriGene clones in human, mouse for SOGA1 (see all 10)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for SOGA1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SOGA1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SOGA1
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for SOGA1
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      QuantiTect SYBR Green Assays in human, mouse, rat SOGA1
      QuantiFast Probe-based Assays in human, mouse, rat SOGA1

    Additional mRNA sequence: 

    AK094762.1 AK126630.1 AL833153.1 BC113405.1 BC113433.1 

    11 DOTS entries:

    DT.447504  DT.100018265  DT.91703933  DT.100740201  DT.65288417  DT.40109885  DT.86842817  DT.97795757 
    DT.97803215  DT.91944842  DT.97815663 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SOGA1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGAATAACTG
    SOGA1 Expression
    About this image

    SOGA1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SOGA1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.460807
        Custom PCR Arrays for SOGA1
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    QuantiFast Probe-based Assays in human, mouse, rat SOGA1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SOGA1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SOGA1 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Soga11 , 5 RIKEN cDNA 9830001H06 gene5
    suppressor of glucose, autophagy associated 11
    87.28(n)1
    91.89(a)1
      2 (77.91 cM)5
    3207061  NM_001164663.11  NP_001158135.11 
     1570157995 
    chicken
    (Gallus gallus)
    Aves SOGA11 suppressor of glucose, autophagy associated 1 76.03(n)
    73.22(a)
      419159  XM_004946981.1  XP_004947038.1 
    lizard
    (Anolis carolinensis)
    Reptilia SOGA16
    suppressor of glucose, autophagy associated 1
    67(a)
    1 ↔ 1
    4(135171938-135269098)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia soga11 suppressor of glucose, autophagy associated 1 65.31(n)
    64.69(a)
      100493417  XM_002942285.2  XP_002942331.2 
    zebrafish
    (Danio rerio)
    Actinopterygii soga11 suppressor of glucose, autophagy associated 1 57.83(n)
    53.98(a)
      797906  XM_001338326.5  XP_001338362.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG183046
    --
    12(a)
    1 → many
    2L(6932545-6942814)
    worm
    (Caenorhabditis elegans)
    Secernentea tag-2416
    Protein TAG-241, isoform a (tag-241) mRNA, complet...
    12(a)
    1 → many
    X(11826093-11836145) WBGene00044079


    ENSEMBL Gene Tree for SOGA1 (if available)
    TreeFam Gene Tree for SOGA1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SOGA1 gene
    MTCL12  SOGA32  
    3 SIMAP similar genes for SOGA1 using alignment to 3 protein entries:     SOGA1_HUMAN (see all proteins):
    C6orf174    SOGA3    SOGA2

    SOGA1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SOGA1 (see all 1723)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1137527981,2
    C,F--35405500(+) ATTACG/ACTTCA 1 -- int11Minor allele frequency- A:0.50CSA 2
    rs1128031041,2
    C--35405536(+) GTGTC-/TTTTTT 1 -- int11Minor allele frequency- T:0.00CSA 2
    rs1888797531,2
    --35405537(+) TGTCTC/TTTTTT 1 -- int10--------
    rs1416291141,2
    --35405577(+) GAAAAC/GTTCAA 1 -- int10--------
    rs1932358401,2
    --35405788(+) AGATCC/TGCTGG 1 -- int10--------
    rs1827391511,2
    --35406071(+) GCCCAA/CGGATG 1 -- ut310--------
    rs60721771,2
    H--35406160(+) CCAGGC/ATGAGT 1 -- ut314Minor allele frequency- A:0.00NS EA 416
    rs1867892891,2
    --35406255(+) CTGGGA/GGTTGG 1 -- int10--------
    rs1912506561,2
    C--35406272(+) TTTTTC/GGCACT 1 -- int10--------
    rs1842182511,2
    --35406355(+) ATTTCA/TTTCAG 1 -- int10--------

    HapMap Linkage Disequilibrium report for SOGA1 (35405845 - 35492089 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for SOGA1: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SOGA1
    DNA2.0 Custom Variant and Variant Library Synthesis for SOGA1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SOGA1 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with SOGA1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Adiponectin lowers glucose production by increasing SOGA. (PubMed id 20813965)1, 2, 3 Cowerd R.B.... Combs T.P. (Am. J. Pathol. 2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
    5. Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10048485)1, 2 Nagase T.... Ohara O. (DNA Res. 1998)
    6. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    7. Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C.... Cristea I.M. (Mol. Cell. Proteomics 2012)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    10. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 140710 HGNC: 16111 Ensembl:ENSG00000149639 euGenes: HUgn140710 ECgene: SOGA1
    H-InvDB: SOGA1

    (According to HUGE)
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    HUGE: KIAA0889

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SOGA1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SOGA1 gene:
    Search GeneIP for patents involving SOGA1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     OriGene Antibodies for SOGA1   OriGene RNAi products in human, mouse, rat for SOGA1  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for SOGA1  
     OriGene qSTAR qPCR primer pairs in human, mouse for SOGA1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SOGA1   OriGene Custom Protein Services for SOGA1  

     
     
     Block miRNA regulation of human, mouse, rat SOGA1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing SOGA1
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SOGA1 Predesigned siRNA for gene silencing in human, mouse, rat SOGA1
     QuantiFast Probe-based Assays in human, mouse, rat SOGA1 QuantiTect SYBR Green Assays in human, mouse, rat SOGA1
     Custom PCR Arrays for SOGA1 Search Chromatin IP Primers for SOGA1
     Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat SOGA1 Search GeneGlobe Interaction Network for SOGA1
     Search Regulatory tfbs for SOGA1
     GenScript Custom Purified and Recombinant Proteins Services for SOGA1 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for SOGA1
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     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
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     Search Tocris compounds for SOGA1
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     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
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     See all of Abcam's Antibodies, Kits and Proteins for SOGA1
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     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for SOGA1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SOGA1
     SwitchGear 3'UTR luciferase reporter plasmids for SOGA1
     SwitchGear Promoter luciferase reporter plasmids for SOGA1
     ThermoFisher Antibodies for SOGA1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SOGA1
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SOGA1
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SOGA1
     LSBio Antibodies in human, mouse, rat for SOGA1
    Customized transgenic rodents for:
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     Off-target effect monitoring
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     Tissue-specific gene expresssion
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     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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