SOCS7 Gene
protein-coding GIFtS: 57
GCID: GC17P036508
|
|
suppressor of cytokine signaling 7
| |
Aliases
for SOCS7 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Suppressor Of Cytokine Signaling 71 2 | | NAP-42 3 | | NAP41 2 3 | | SOCS-72 3 | | NCKAP41 2 | | Nck, Ash And Phospholipase C Binding Protein2 | | Nck, Ash And Phospholipase C Gamma-Binding Protein2 3 | | SOCS63 | | Nck-Associated Protein 42 3 | | |
Export aliases for SOCS7 gene to outside databasesPrevious GC identifers: GC14P049305 GC14P053483 GC17P036869 GC17P033761 GC17P032304 |
Summaries
for SOCS7 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: SOCS7_HUMAN, O14512Function: Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions ininsulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibitsalso prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in thecytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of targetproteins (By similarity)
Gene Wiki entry for SOCS7
|
Genomic Views
for SOCS7 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SOCS7 gene promoter:
MAZR ATF-2 GATA-1 Egr-2 POU2F1 POU2F1a STAT3 c-Myb SEF-1 (1) c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for SOCS7
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SOCS7 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q12 Ensembl cytogenetic band: 17q12 HGNC cytogenetic band: 17q21.1SOCS7 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P036508: view genomic region
(about GC identifiers)
Start:
|
36,508,005 bp from pter |
End:
|
36,556,019 bp from pter |
Size:
|
48,015 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr17+,PATCHES 36,508,004-36,556,019 |
|
Proteins
for SOCS7 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SOCS7_HUMAN, O14512 (See
protein sequence)Recommended Name: Suppressor of cytokine signaling 7 Size: 581 amino acids; 62969 Da
Subunit: Interacts with phosphorylated IRS4 and PIK3R1 (By similarity). Interacts, via the third proline-rich region,with the second SH3 domain of the adapter protein NCK1. Also interacts with GRB2, INSR, IRS1, PLCG1, SORBS3/vinexin,and phosphorylated STAT3 and STAT5. Interacts with SEPT6
Subcellular location: Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus. Note=Mostlycytoplasmic, but shuttles between the cytoplasm and the nucleus. Rapidly relocalizes to the nucleus after UVirradiation. Cytoplasmic location depends upon SEPT7 presence
Sequence caution: Sequence=AAI28608.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. The N-terminus maybe contaminated with vector sequence; Sequence=BAA22432.1; Type=Erroneous termination; Positions=582; Note=Translatedas stop;
Secondary accessions: A2VCU2 Q0IJ63Alternative splicing: 2 isoforms: O14512-1 O14512-2 Explore the universe of human proteins at neXtProt for SOCS7: NX_O14512
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O14512
SOCS7 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055413.1
ENSEMBL proteins: ENSP00000330659 ENSP00000464034 ENSP00000462569
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
SOCS7 for ontologies About GeneDecksing
SOCS7 Antibody Products:
Assay Products for SOCS7: |
Protein
Domains /
Families
for SOCS7 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SOCS7 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O14512ProtoNet protein and cluster: O14512 1 Blocks protein family: IPB001496 SOCS protein
UniProtKB/Swiss-Prot: SOCS7_HUMAN, O14512Domain: The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3ubiquitin ligase complexes (By similarity). It is required for IRS1 ubiquitination and subsequent proteasomaldegradationSimilarity: Contains 1 SH2 domainSimilarity: Contains 1 SOCS box domain |
Function
for SOCS7 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SOCS7_HUMAN, O14512Function: Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions ininsulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibitsalso prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in thecytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of targetproteins (By similarity)Induction: By IL6/interleukin-6, prolactin and growth hormone
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SOCS7 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SOCS7
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for SOCS7 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SOCS7 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SOCS7 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
SOCS7 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for SOCS7:
Animal Models:
Mouse knock-outs for SOCS7: Socs7tm1Pbro Socs7tm1Wsa
9 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Socs7):
SOCS7 for phenotypes About GeneDecksing
|
Pathways & Interactions
for SOCS7 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Jak-STAT signaling pathway | | | 2 | Development_Prolactin receptor signaling | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for SOCS7
1 
Kegg Pathway (Kegg details for SOCS7):
UniProtKB/Swiss-Prot: SOCS7_HUMAN, O14512Pathway: Protein modification; protein ubiquitination
SOCS7 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SOCS7
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/61 Interacting proteins for SOCS7 (O145121, 2, 3 ENSP000003306594) via UniProtKB, MINT, STRING, and/or I2D (see all 61)
About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008150 | biological_process |
ND | -- | | GO:0008286 | insulin receptor signaling pathway |
IEA | -- | | GO:0009968 | negative regulation of signal transduction |
IEA | -- | | GO:0016567 | protein ubiquitination |
IEA | -- | | GO:0035556 | intracellular signal transduction |
IEA | -- |
SOCS7 for ontologies About GeneDecksing
|
Drugs & Compounds
for SOCS7 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SOCS7
Search CenterWatch for drugs/clinical trials and news about SOCS7
|
Transcripts
for SOCS7 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SOCS7 gene: NM_014598.2 Unigene Cluster for SOCS7: Suppressor of cytokine signaling 7 Hs.514132 [show with all ESTs]Unigene Representative Sequence: NM_0145984 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000331159 ENST00000577233(uc002hqa.3 uc010cvl.3) ENST00000584132(uc002hqb.3)
ENST00000580660
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SOCS7 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SOCS7
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SOCS7 (NM_014598) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SOCS7 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SOCS7 |
Additional cDNA sequence: AB005216.1 AK094338.1 BC121030.1 BC121031.1 BC128607.1 4 DOTS entries: DT.413889 DT.95264284 DT.92418134 DT.75102249 24/186 AceView cDNA sequences (see all 186): AW002013 AL135718 BQ010275 AW236830 BQ920093 AA812562 BM723282 AI452916 AL045666 AI280087 AI193124 BF060680 AI078587 AI628681 AI831729 AI796201 AW016707 AA514206 AA058418 AI479144 BQ957188 AI247733 BQ186459 AI675289
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for SOCS7 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | - | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SOCS7
|
Expression
for SOCS7 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SOCS7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See SOCS7 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SOCS7
SOURCE GeneReport for Unigene cluster: Hs.514132
UniProtKB/Swiss-Prot: SOCS7_HUMAN, O14512Tissue specificity: Expressed in brain and leukocytes. Also in fetal lung fibroblasts and fetal brain
SABiosciences Custom PCR Arrays for SOCS7
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SOCS7
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SOCS7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SOCS7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SOCS7 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SOCS7 |
Orthologs
for SOCS7 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SOCS7 gene from 5/19 species (see all 19) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
SOCS71 |
suppressor of cytokine signaling 7 |
84.55(n)
93.13(a) |
|
426232 XM_423895.3 XP_423895.3 |
lizard
(Anolis carolinensis) |
Reptilia |
SOCS76 |
-- |
99(a) |
1 ↔ 1 |
6(73956177-73959988) |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
Str.25992 |
Transcribed sequence with moderate similarity to protein more |
79.17(n) |
|
AL848459.2 |
zebrafish
(Danio rerio) |
Actinopterygii |
LOC1005381861 |
uncharacterized LOC100538186 |
62.43(n)
64.06(a) |
|
100538186 XM_003199461.1 XP_003199509.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Socs44A6Socs16D6 |
Suppressor of Cytokine Signaling at 16D |
20(a)12(a) |
possible ortholog1 ↔ 1 |
2R(4015136-4016981) X(17714797-17721553) |
ENSEMBL Gene Tree for SOCS7 (if available)
TreeFam Gene Tree for SOCS7 (if available) |
Paralogs
for SOCS7 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SOCS7 gene
- SOCS32 SOCS42 SOCS52 SOCS62 SOCS12 CISH2 SOCS22
1 SIMAP similar gene for SOCS7 using alignment to 3 protein entries: SOCS7_HUMAN (see all proteins):SOCS2
SOCS7 for paralogs About GeneDecksing
|
Genomic Variants
for SOCS7 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SOCS7 (36508005 - 36556019 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for SOCS7
3 CNVs: 4034 2224 7157
2 Indels: 25825 25826 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SOCS7 |
|
Disorders
/ Diseases
for SOCS7 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SOCS7 for disorders About GeneDecksing
OMIM gene information: 608788
OMIM disorders: --
4  diseases for SOCS7: About MalaCardschronic fatigue syndrome hepatitis c breast cancer hepatitis
1 disease from the University of Copenhagen DISEASES database for SOCS7:Chronic fatigue syndrome Human Genome Epidemiology (HuGE) Navigator: SOCS7 (6 documents)
Export disorders for SOCS7 gene to outside databases
|
Publications
for SOCS7 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SOCS7 gene, integrated from 9 sources (see all 25):
(articles sorted by number of sources associating them with SOCS7) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A novel ligand for an SH3 domain of the adaptor protein Nck bears an SH2 domain and nuclear signaling motifs. (PubMed id 9344857)1, 2, 3 Matuoka K.... Takenawa T. (1997)
- Suppressor of cytokine signaling 7 inhibits prolactin, growth hormone, and leptin signaling by interacting with STAT5 or STAT3 and attenuating their nuclear translocation. (PubMed id 15677474)1, 2, 9 Martens N....Gertler A. (2005)
- Expression of SOCS genes in normal and leukemic human leukocytes stimulated by prolactin, growth hormone and cytokines. (PubMed id 10969179)1, 2, 9 Dogusan Z.... Hooghe R. (2000)
- Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7. (PubMed id 17803907)1, 2 Kremer B.E.... Macara I.G. (2007)
- DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)1, 2 Zody M.C.... Nusbaum C. (2006)
- Deletion of SOCS7 leads to enhanced insulin action and enlarged islets of Langerhans. (PubMed id 16127460)1, 2 Banks A.S....Rothman P.B. (2005)
- The suppressor of cytokine signaling (SOCS)-7 interacts with the actin cytoskeleton through vinexin. (PubMed id 15242778)1, 2 Martens N.... Hooghe-Peters E.L. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The SOCS box: a tale of destruction and degradation. (PubMed id 12076535)1, 3 Kile B.T....Hilton D.J. (2002)
- LNCaP prostate cancer cells with autocrine interleukin -6 expression are resistant to IL-6-induced neuroendocrine differentiation due t o increased expression of suppressors of cytokine signaling. (PubMed id 22213096)1 Ge D....You Z. (2012)
|
External Searches for SOCS7 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SOCS7 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SOCS7 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SOCS7 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SOCS7 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SOCS7 gene:
Search GeneIP for patents involving SOCS7
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SOCS7 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for SOCS7 | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SOCS7 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SOCS7 | | | OriGene Protein Over-expression Lysate for SOCS7 | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for SOCS7 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SOCS7 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SOCS7 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SOCS7 | | OriGene Custom Protein Services for SOCS7 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SOCS7 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SOCS7 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SOCS7 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SOCS7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SOCS7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SOCS7 |
| |
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| | | | Search Tocris compounds for SOCS7 |
| |  |  |  |  | | | | |
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 |
 |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SOCS7 |
|  |  |  | | | | ThermoFisher Antibodies for SOCS7 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SOCS7 |
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