SOCS5 Gene
protein-coding GIFtS: 63
GCID: GC02P046926
|
|
suppressor of cytokine signaling 5
| |
Aliases
for SOCS5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Suppressor Of Cytokine Signaling 51 2 | | Cish51 2 | | CIS61 2 3 5 | | Cytokine-Inducible SH2 Protein 62 3 | | CISH61 2 3 | | Cytokine-Inducible SH2-Containing Protein 52 3 | | SOCS-51 2 3 | | CIS-62 3 | | KIAA06711 3 5 | | CISH53 |
Export aliases for SOCS5 gene to outside databasesPrevious GC identifers: GC02P046943 GC02P047094 GC02P046900 GC02P046837 GC02P046663 |
Summaries
for SOCS5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SOCS5:
The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to thesuppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCSfamily members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function ofthis protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical proteinhave been reported. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: SOCS5_HUMAN, O75159Function: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signaltransduction. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of targetproteins. Inhibits for instance EGF signaling by mediating the degradation of the EGF receptor/EGFR. Involved in theregulation of T-helper cell differentiation by inhibiting of the IL4 signaling pathway which promotes differentiationinto the Th2 phenotype. Can also partially inhibit IL6 and LIF signaling
Gene Wiki entry for SOCS5
|
Genomic Views
for SOCS5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022184.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SOCS5 gene promoter:
NF-AT4 NF-AT2 NF-AT3 PPAR-gamma2 NF-AT1 NF-AT
Other transcription factors
Search SABiosciences Chromatin IP Primers for SOCS5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SOCS5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p21 Ensembl cytogenetic band: 2p21 HGNC cytogenetic band: 2p21SOCS5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P046926: view genomic region
(about GC identifiers)
Start:
|
46,926,091 bp from pter |
End:
|
46,990,268 bp from pter |
Size:
|
64,178 bases |
Orientation:
|
plus strand |
|
Proteins
for SOCS5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SOCS5_HUMAN, O75159 (See
protein sequence)Recommended Name: Suppressor of cytokine signaling 5 Size: 536 amino acids; 61246 Da
Subunit: Interacts with IL4R; inhibits IL4 signaling (By similarity). Interacts with EGFR. Interacts with TCEB1 ANDTCEB2; mediates EGFR ubiquitination and degradation
Sequence caution: Sequence=BAA31646.2; Type=Erroneous initiation;
Secondary accessions: Q53SD4 Q8IYZ4Explore the universe of human proteins at neXtProt for SOCS5: NX_O75159
Post-translational modifications:
Phosphorylated. Phosphorylation is induced by EGF1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O75159
SOCS5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_054730.1 NP_659198.1
ENSEMBL proteins: ENSP00000305133 ENSP00000378330
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005622 | intracellular |
-- | -- |
SOCS5 for ontologies About GeneDecksing
SOCS5 Antibody Products:
Assay Products for SOCS5: |
Protein
Domains /
Families
for SOCS5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SOCS5 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O75159ProtoNet protein and cluster: O75159 1 Blocks protein family: IPB001496 SOCS protein
UniProtKB/Swiss-Prot: SOCS5_HUMAN, O75159Domain: The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3ubiquitin ligase complexesSimilarity: Contains 1 SH2 domainSimilarity: Contains 1 SOCS box domain |
Function
for SOCS5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SOCS5_HUMAN, O75159Function: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signaltransduction. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of targetproteins. Inhibits for instance EGF signaling by mediating the degradation of the EGF receptor/EGFR. Involved in theregulation of T-helper cell differentiation by inhibiting of the IL4 signaling pathway which promotes differentiationinto the Th2 phenotype. Can also partially inhibit IL6 and LIF signalingInduction: Up-regulated by EGF (at protein level)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SOCS5 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SOCS5 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): SOCS5 (NM_014011) | |  | Sino Biological Human cDNA Clone for SOCS5 | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SOCS5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SOCS5 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SOCS5 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
SOCS5 for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Socs5tm1Wsa for SOCS5
4 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Socs5):
SOCS5 for phenotypes About GeneDecksing
|
Pathways & Interactions
for SOCS5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/9 super-pathways (see all 9) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | ErbB4 Pathway | | | 2 | Immune response_IL-4 signaling pathway | | | 3 | PEDF Induced Signaling | | | 4 | TGF-Beta Pathway | | | 5 | IL-4 signaling Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for SOCS5
5/8 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for SOCS5 (see all 8)
1  GeneGo (Thomson Reuters) Pathway for SOCS5
3  BioSystems Pathways for SOCS5
1 
Kegg Pathway (Kegg details for SOCS5):
UniProtKB/Swiss-Prot: SOCS5_HUMAN, O75159Pathway: Protein modification; protein ubiquitination
SOCS5 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SOCS5
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/54 Interacting proteins for SOCS5 (O751592, 3 ENSP000003051334) via UniProtKB, MINT, STRING, and/or I2D (see all 54)
About this table
Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11): About this table
SOCS5 for ontologies About GeneDecksing
|
Drugs & Compounds
for SOCS5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SOCS5
Search CenterWatch for drugs/clinical trials and news about SOCS5
|
Transcripts
for SOCS5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SOCS5 gene (2 alternative transcripts): NM_014011.4 NM_144949.2 Unigene Cluster for SOCS5: Suppressor of cytokine signaling 5 Hs.468426 [show with all ESTs]Unigene Representative Sequence: NM_1449492 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000306503(uc002rvf.3 uc002rvg.3) ENST00000394861
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SOCS5 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SOCS5 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): SOCS5 (NM_014011) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SOCS5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SOCS5 |
Additional cDNA sequence: AB014571.1 AF073958.1 AK290194.1 AK296796.1 AL136896.1 BC032862.1 5 DOTS entries: DT.440803 DT.95342969 DT.95222954 DT.95163970 DT.120829691 24/94 AceView cDNA sequences (see all 94): AA583249 AF073958 BM973647 AW196048 R80422 AW262882 AB014571 BM993963 AL136896 AI088496 T17373 CA435702 BM955863 NM_144949 NM_014011 AI826316 BQ881514 AA971583 BU625772 CD642525 BI553037 BQ015062 BP429961 BC032862
GeneLoc Exon Structure
|
Expression
for SOCS5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SOCS5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AACTTGCACC
About this image
See SOCS5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SOCS5
SOURCE GeneReport for Unigene cluster: Hs.468426
SABiosciences Expression via Pathway-Focused PCR Arrays including SOCS5:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SOCS5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SOCS5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SOCS5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SOCS5 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SOCS5 |
Orthologs
for SOCS5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SOCS5 gene from 5/17 species (see all 17) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
SOCS51 |
suppressor of cytokine signaling 5 |
81.65(n)
91.04(a) |
|
428570 NM_001127314.1 NP_001120786.1 |
lizard
(Anolis carolinensis) |
Reptilia |
SOCS56 |
-- |
82(a) |
1 ↔ 1 |
2(142930592-142932190) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.115172 |
Xenopus laevis transcribed sequence with strong similarity more |
75.85(n) |
|
BX848217.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
socs5b1 |
suppressor of cytokine signaling 5b |
64.44(n)
72.16(a) |
|
559639 NM_001113797.1 NP_001107269.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Socs36E3 |
JAK-STAT cascade |
69(a) |
|
36D3 -- |
ENSEMBL Gene Tree for SOCS5 (if available)
TreeFam Gene Tree for SOCS5 (if available) |
Paralogs
for SOCS5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SOCS5 gene
- SOCS32 SOCS42 SOCS72 SOCS62 SOCS12 CISH2 SOCS22
2 SIMAP similar genes for SOCS5 using alignment to 1 protein entry: SOCS5_HUMAN:DKFZp686J1568 SOCS4
SOCS5 for paralogs About GeneDecksing
5/6 Pseudogenes.org Pseudogenes for SOCS5 (see all 6)
PGOHUM00000237608 PGOHUM00000243746 PGOHUM00000232908 PGOHUM00000249776 PGOHUM00000236788
|
Genomic Variants
for SOCS5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SOCS5 (46926091 - 46990268 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for SOCS5
3 CNVs: 89630 67673 97841
1 Indel: 97840 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SOCS5 |
|
Disorders
/ Diseases
for SOCS5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SOCS5 for disorders About GeneDecksing
OMIM gene information: 607094
OMIM disorders: --
9  diseases for SOCS5: About MalaCardsvogt-koyanagi-harada disease allergic conjunctivitis atopic dermatitis chronic lymphocytic leukemia
lymphocytic leukemia conjunctivitis dermatitis copd
leukemia
1 disease from the University of Copenhagen DISEASES database for SOCS5:Allergic conjunctivitis Human Genome Epidemiology (HuGE) Navigator: SOCS5 (4 documents)
Export disorders for SOCS5 gene to outside databases
|
Publications
for SOCS5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SOCS5 gene, integrated from 9 sources (see all 28):
(articles sorted by number of sources associating them with SOCS5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (2001)
- Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)1, 2, 3 Ishikawa K.... Ohara O. (1998)
- Cloning and expression of CIS6, chromosomal assignment to 3p22 and 2p21 by in situ hybridization. (PubMed id 10773671)1, 2, 9 Magrangeas F....Minvielle S. (2000)
- Suppressors of cytokine signaling 4 and 5 regulate epidermal growth factor receptor signaling. (PubMed id 15590694)1, 2 Kario E....Yarden Y. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The N-terminal domains of SOCS proteins: a conserved r egion in the disordered N-termini of SOCS4 and 5. (PubMed id 22423360)1 Feng Z.P....Norton R.S. (2012)
- Tumour-secreted miR-9 promotes endothelial cell migrat ion and angiogenesis by activating the JAK-STAT pathway. (PubMed id 22773185)1 Zhuang G....Ferrara N. (2012)
- SOCS5 and SOCS6 have similar expression patterns in n ormal and cancer tissues. (PubMed id 22081311)1 Yoon S....Nam S.W. (2012)
- Genome-wide association study of smoking behaviours i n patients with COPD. (PubMed id 21685187)1 Siedlinski M....Silverman E.K. (2011)
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
|
External Searches for SOCS5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SOCS5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SOCS5 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing SOCS5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SOCS5 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SOCS5 gene:
Search GeneIP for patents involving SOCS5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SOCS5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for SOCS5 | | OriGene shRNA RFP for SOCS5 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SOCS5 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SOCS5 | | | OriGene Protein Over-expression Lysate for SOCS5 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SOCS5 | | OriGene 3'-UTR Clone for SOCS5 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SOCS5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SOCS5 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SOCS5 | | OriGene Custom Protein Services for SOCS5 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SOCS5 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SOCS5 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SOCS5 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SOCS5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SOCS5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SOCS5 |
| |
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| | | | Search Tocris compounds for SOCS5 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | SOCS5 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SOCS5 |
|  |  |  | | | | ThermoFisher Antibodies for SOCS5 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SOCS5 |
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