SOCS4 Gene
protein-coding GIFtS: 60
GCID: GC14P055493
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suppressor of cytokine signaling 4(Previous name: suppressor of cytokine signaling 7 )
(Previous symbol: SOCS7)
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Aliases
for SOCS4 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Suppressor Of Cytokine Signaling 41 2 | | SH2 Domain Containing SOCS Box Protein2 | | Suppressor Of Cytokine Signaling 71 2 3 | | CIS45 | | SOCS71 2 3 | | SSI45 | | SOCS-42 3 | | STAT45 | | SOCS-72 3 | | |
Export aliases for SOCS4 gene to outside databasesPrevious GC identifers: GC14P052833 GC18P068015 GC18P067741 GC18P066105 GC14P053484 GC14P054563 GC14P035656 |
Summaries
for SOCS4 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SOCS4:
The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to thesuppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS familymembers are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively splicedtranscript variants encoding the same protein have been found for this gene. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: SOCS4_HUMAN, Q8WXH5Function: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signaltransduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of targetproteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR
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Genomic Views
for SOCS4 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000014.8 NC_018925.1 NT_026437.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SOCS4 gene promoter:
AML1a POU3F2 (N-Oct-5b) POU3F2 (N-Oct-5a) POU3F2 CREB AREB6 STAT3 SEF-1 (1) Ik-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for SOCS4
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SOCS4 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 14q22.1 Ensembl cytogenetic band: 14q22.2 HGNC cytogenetic band: 14q22.1SOCS4 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14P055493: view genomic region
(about GC identifiers)
Start:
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55,493,844 bp from pter |
End:
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55,516,207 bp from pter |
Size:
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22,364 bases |
Orientation:
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plus strand |
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Proteins
for SOCS4 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SOCS4_HUMAN, Q8WXH5 (See
protein sequence)Recommended Name: Suppressor of cytokine signaling 4 Size: 440 amino acids; 50623 Da
1 PDB 3D structure from  and Proteopedia  for SOCS4:2IZV (3D)
Explore the universe of human proteins at neXtProt for SOCS4: NX_Q8WXH5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8WXH5
SOCS4 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_543143.1 NP_955453.1
ENSEMBL proteins: ENSP00000378855 ENSP00000452522 ENSP00000341327
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005622 | intracellular |
-- | -- |
SOCS4 for ontologies About GeneDecksing
SOCS4 Antibody Products:
Assay Products for SOCS4: |
Protein
Domains /
Families
for SOCS4 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SOCS4 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8WXH5ProtoNet protein and cluster: Q8WXH5 1 Blocks protein family: IPB001496 SOCS protein
UniProtKB/Swiss-Prot: SOCS4_HUMAN, Q8WXH5Domain: The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3ubiquitin ligase complexes (By similarity)Similarity: Contains 1 SH2 domainSimilarity: Contains 1 SOCS box domain |
Function
for SOCS4 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SOCS4_HUMAN, Q8WXH5Function: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signaltransduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of targetproteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFRInduction: Up-regulated by EGF
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SOCS4 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SOCS4 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): SOCS4 (NM_080867) | |  | Sino Biological Human cDNA Clone for SOCS4 | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SOCS4 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SOCS4 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SOCS4 |
2 GenomeRNAi human phenotypes for SOCS4:
|
Pathways & Interactions
for SOCS4 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Unified GeneCards pathways - 5/7 super-pathways (see all 7) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | ErbB4 Pathway | | | 2 | Type II diabetes mellitus | | | 3 | PEDF Induced Signaling | | | 4 | TGF-Beta Pathway | | | 5 | Jak-STAT signaling pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/7 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for SOCS4 (see all 7)
2  BioSystems Pathways for SOCS4
3 
Kegg Pathways (Kegg details for SOCS4):
UniProtKB/Swiss-Prot: SOCS4_HUMAN, Q8WXH5Pathway: Protein modification; protein ubiquitination
SOCS4 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SOCS4
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/58 Interacting proteins for SOCS4 (Q8WXH52, 3 ENSP000003413274) via UniProtKB, MINT, STRING, and/or I2D (see all 58)
About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity |
IDA | 15590694 | | GO:0016567 | protein ubiquitination |
IEA | -- | | GO:0035556 | intracellular signal transduction |
IEA | -- | | GO:0040008 | regulation of growth |
IEA | -- |
SOCS4 for ontologies About GeneDecksing
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Drugs & Compounds
for SOCS4 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SOCS4
Search CenterWatch for drugs/clinical trials and news about SOCS4
|
Transcripts
for SOCS4 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SOCS4 gene (2 alternative transcripts): NM_080867.2 NM_199421.1 Unigene Cluster for SOCS4: Suppressor of cytokine signaling 4 Hs.744302 [show with all ESTs]Unigene Representative Sequence: NM_1994214 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000395472(uc001xbo.3 uc001xbp.3) ENST00000555846 ENST00000553735
ENST00000339298
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SOCS4 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SOCS4 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): SOCS4 (NM_080867) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SOCS4 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SOCS4 |
Additional cDNA sequence: AF424815.1 AK056685.1 AK124083.1 AK126195.1 AK127299.1 BC060790.1 BX161418.1 BX648734.1 CR933659.1 7 DOTS entries: DT.101961928 DT.99974426 DT.91955278 DT.100751679 DT.212307 DT.91706531 DT.100746814 24/121 AceView cDNA sequences (see all 121): AF424815 AI653056 AI000715 CB045775 BC060790 BG399272 AI348677 BX648734 NM_199421 NM_080867 AK056685 BQ446934 BX491558 BI492088 AW130886 BU951909 AK126195 BU741261 BU786158 BX506489 BF446961 BU686061 BM479640 BX161418
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for SOCS4 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3a | · | 3b |
|---|
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| SP1: | | | | | | | | | | | | | |
| SP2: | | | | | - | | | | | | | |
ECgene alternative splicing isoforms for SOCS4
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Expression
for SOCS4 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SOCS4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TACTCGAATA
About this image
See SOCS4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SOCS4
SOURCE GeneReport for Unigene cluster: Hs.744302
SABiosciences Expression via Pathway-Focused PCR Arrays including SOCS4:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SOCS4
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SOCS4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SOCS4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SOCS4 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SOCS4 |
Orthologs
for SOCS4 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SOCS4 gene from 6/15 species (see all 15) About this table
ENSEMBL Gene Tree for SOCS4 (if available)
TreeFam Gene Tree for SOCS4 (if available) |
Paralogs
for SOCS4 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SOCS4 gene
- SOCS32 SOCS52 SOCS72 SOCS62 SOCS12 CISH2 SOCS22
2 SIMAP similar genes for SOCS4 using alignment to 1 protein entry: SOCS4_HUMAN:DKFZp686J1568 SOCS5
SOCS4 for paralogs About GeneDecksing
|
Genomic Variants
for SOCS4 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 14 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SOCS4 (55493844 - 55516207 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for SOCS4
1 CNV: 5746 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SOCS4 |
|
Disorders
/ Diseases
for SOCS4 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SOCS4 for disorders About GeneDecksing
OMIM gene information: 605118
OMIM disorders: --
4  diseases for SOCS4: About MalaCardsmeningioma influenza breast cancer leukemia
Human Genome Epidemiology (HuGE) Navigator: SOCS4 (10 documents)
Export disorders for SOCS4 gene to outside databases
|
Publications
for SOCS4 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SOCS4 gene, integrated from 9 sources (see all 19):
(articles sorted by number of sources associating them with SOCS4) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Structure of the SOCS4-ElonginB/C complex reveals a distinct SOCS box interface and the molecular basis for SOCS-dependent EGFR degradation. (PubMed id 17997974)1, 2 Bullock A.N....Knapp S. (2007)
- Suppressors of cytokine signaling 4 and 5 regulate epidermal growth factor receptor signaling. (PubMed id 15590694)1, 2 Kario E....Yarden Y. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The SOCS box: a tale of destruction and degradation. (PubMed id 12076535)1, 3 Kile B.T....Hilton D.J. (2002)
- Negative regulation of cytokine signaling: STAT-induc ed STAT inhibitor. (PubMed id 10500304)1, 3 Naka T....Kishimoto T. (1999)
- Higher expression levels of SOCS 1,3,4,7 are associat ed with earlier tumour stage and better clinical outcome in human breast cancer . (PubMed id 20433750)1, 9 Sasi W....Mokbel K. (2010)
- The N-terminal domains of SOCS proteins: a conserved r egion in the disordered N-termini of SOCS4 and 5. (PubMed id 22423360)1 Feng Z.P....Norton R.S. (2012)
- Suppressor of cytokine signaling 4 detected as a novel gastric cancer suppressor gene using double combination array analysis. (PubMed id 22127425)1 Kobayashi D....Nakao A. (2012)
- MicroRNA-98 and let-7 regulate expression of suppress or of cytokine signaling 4 in biliary epithelial cells in response to Cryptospo ridium parvum infection. (PubMed id 20486857)1 Hu G....Chen X.M. (2010)
- Polymorphisms in innate immunity genes and risk of ch ildhood leukemia. (PubMed id 20438785)1 Han S....Kang D. (2010)
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External Searches for SOCS4 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SOCS4 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SOCS4 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SOCS4 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SOCS4 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SOCS4 gene:
Search GeneIP for patents involving SOCS4
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SOCS4 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for SOCS4 | | OriGene shRNA RFP for SOCS4 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SOCS4 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SOCS4 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for SOCS4 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SOCS4 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SOCS4 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SOCS4 | | OriGene Custom Protein Services for SOCS4 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SOCS4 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SOCS4 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SOCS4 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SOCS4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SOCS4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SOCS4 |
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| | | | Search Tocris compounds for SOCS4 |
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 | | | SOCS4 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SOCS4 |
|  |  |  | | | | ThermoFisher Antibodies for SOCS4 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SOCS4 |
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