SNX9 Gene
protein-coding GIFtS: 56
GCID: GC06P158153
|
|
sorting nexin 9
| |
Aliases
for SNX9 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Sorting Nexin 91 2 | | MSTP1552 | | SH3PX11 2 3 5 | | WISP2 | | SH3PXD3A1 2 3 | | SH3 And PX Domain-Containing Protein SH3PX12 | | SDP11 2 | | Sorting Nexin-92 | | SH3 And PX Domain-Containing Protein 12 3 | | Wiskott-Aldrich Syndrome Protein (WASP) Interactor Protein2 | | SH3 And PX Domain-Containing Protein 3A2 3 | | Protein SDP13 | | MST1552 | | |
Export aliases for SNX9 gene to outside databasesPrevious GC identifers: GC06P157685 GC06P158117 GC06P158110 GC06P155760 |
Summaries
for SNX9 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SNX9:
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is aphosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiledcoil region, like some family members, but does contain a SH3 domain near its N-terminus. This protein interacts withthe cytoplasmic domains of the precursor but not the processed forms of a disintegrin and metalloprotease domain 9 and15. This protein binds the beta-appendage domain of adaptor protein 2 and may function to assist adaptor protein 2 inits role at the plasma membrane. This protein interacts with activated Cdc42-associated kinase-2 to regulate thedegradation of epidermal growth factor receptor protein. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: SNX9_HUMAN, Q9Y5X1Function: May be involved in several stages of intracellular trafficking. Plays a role in endocytosis viaclathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role inmacropinocytosis. Promotes internalization of TNFR. Promotes degradation of EGFR after EGF signaling. Stimulates theGTPase activity of DNM1. Promotes DNM1 oligomerization. Promotes activation of the Arp2/3 complex by WASL, and therebyplays a role in the reorganization of the F-actin cytoskeleton. Binds to membranes enriched in phosphatidylinositol4,5-bisphosphate and promotes membrane tubulation. Has lower affinity for membranes enriched in phosphatidylinositol3-phosphate
Gene Wiki entry for SNX9
|
Genomic Views
for SNX9 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_025741.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SNX9 gene promoter:
AP-2alpha isoform 3 AP-2alpha isoform 2 AP-2alpha AP-2alphaA
Other transcription factors
Search SABiosciences Chromatin IP Primers for SNX9
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SNX9 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6q25.1-q26 Ensembl cytogenetic band: 6q25.3 HGNC cytogenetic band: 6q25.1-q26SNX9 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06P158153: view genomic region
(about GC identifiers)
Start:
|
158,244,281 bp from pter |
End:
|
158,366,109 bp from pter |
Size:
|
121,829 bases |
Orientation:
|
plus strand |
|
Proteins
for SNX9 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SNX9_HUMAN, Q9Y5X1 (See
protein sequence)Recommended Name: Sorting nexin-9 Size: 595 amino acids; 66592 Da
Subunit: Homodimer, and homooligomer. Heterodimer with SNX18. Interacts with ITCH. Interacts (via SH3 domain) withTNK2, WASL and ARP3. Identified in a complex with TNK2 and clathrin heavy chains. Identified in a complex with theAP-2 complex, clathrin and DNM2. Interacts (via SH3 domain) with DNM1 and DNM2. Identified in an oligomeric complexcontaining DNM1 and SNX9. Interacts with ADAM9 and ADAM15 cytoplasmic tails
Subcellular location: Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane;Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, clathrin-coated vesicle. Golgi apparatus,trans-Golgi network. Cell projection, ruffle. Cytoplasm. Note=Localized at sites of endocytosis at the cell membrane.Detected on newly formed macropinosomes. Transiently recruited to clathrin-coated pits at a late stage ofclathrin-coated vesicle formation. Colocalizes with the actin cytoskeleton at the cell membrane
6 PDB 3D structures from  and Proteopedia  for SNX9:2RAI (3D)
2RAJ (3D)
2RAK (3D)
3DYT (3D)
3DYU (3D)
3LGE (3D)
Secondary accessions: Q9BSI7 Q9BVM1 Q9UJH6 Q9UP20Explore the universe of human proteins at neXtProt for SNX9: NX_Q9Y5X1
Post-translational modifications:
Ubiquitinated by ITCH1
Phosphorylated on tyrosine residues by TNK2. Phosphorylation promotes its activity in the degradation of EGFR1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y5X1
SNX9 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_057308.1
ENSEMBL proteins: ENSP00000376024 ENSP00000446165 ENSP00000252631 Reactome Protein details: Q9Y5X1
Human Recombinant Protein Products:
Gene Ontology (GO): 5/12 cellular component terms (GO ID links to tree view) (see all 12): About this table
SNX9 for ontologies About GeneDecksing
SNX9 Antibody Products:
Assay Products for SNX9: |
Protein
Domains /
Families
for SNX9 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SNX9 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9Y5X1ProtoNet protein and cluster: Q9Y5X1 2 Blocks protein families: IPB001452 SH3 domain signature IPB001683 Phox-like
UniProtKB/Swiss-Prot: SNX9_HUMAN, Q9Y5X1Domain: The PX domain mediates interaction with membranes enriched in phosphatidylinositol phosphate. Has high affinityfor phosphatidylinositol 4,5-bisphosphate, but can also bind to membranes enriched in other phosphatidylinositolphosphatesSimilarity: Belongs to the sorting nexin familySimilarity: Contains 1 BAR domainSimilarity: Contains 1 PX (phox homology) domainSimilarity: Contains 1 SH3 domain |
Function
for SNX9 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SNX9_HUMAN, Q9Y5X1Function: May be involved in several stages of intracellular trafficking. Plays a role in endocytosis viaclathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role inmacropinocytosis. Promotes internalization of TNFR. Promotes degradation of EGFR after EGF signaling. Stimulates theGTPase activity of DNM1. Promotes DNM1 oligomerization. Promotes activation of the Arp2/3 complex by WASL, and therebyplays a role in the reorganization of the F-actin cytoskeleton. Binds to membranes enriched in phosphatidylinositol4,5-bisphosphate and promotes membrane tubulation. Has lower affinity for membranes enriched in phosphatidylinositol3-phosphate
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SNX9 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SNX9
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector: SNX9 (NM_016224) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SNX9 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNX9 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNX9 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
SNX9 for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for SNX9:
|
Pathways & Interactions
for SNX9 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Clathrin derived vesicle budding | | | 2 | Clathrin-dependent protein traffic | | | 3 | Membrane Trafficking | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2  GeneGo (Thomson Reuters) Pathways for SNX9
4 
Reactome Pathways for SNX9
SNX9 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SNX9
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/32 Interacting proteins for SNX9 (Q9Y5X11, 2, 3 ENSP000003760244) via UniProtKB, MINT, STRING, and/or I2D (see all 32)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| ITCH | Q96J022, 3, ENSP000003639984 | MINT-7889571 MINT-7889591 MINT-7889673 MINT-7890033 MINT-7889610 MINT-7889619 MINT-7889689 I2D:
score=2 STRING: ENSP00000363998 | | DNM2 | P505702, 3, ENSP000003527214 | MINT-61335 MINT-61336 MINT-7302047 MINT-7301992 MINT-61334 MINT-61332 I2D:
score=4 STRING: ENSP00000352721 | | SYNJ1 | O434262, 3, ENSP000003222344 | MINT-62869 MINT-62867 MINT-62870 MINT-62871 I2D:
score=1 STRING: ENSP00000322234 | | ASAP1 | Q9ULH12, 3, ENSP000003502974 | MINT-7145899 MINT-7145843 I2D:
score=1 STRING: ENSP00000350297 | | ADAM15 | Q134442, 3, ENSP000003494364 | MINT-2792432 I2D:
score=5 STRING: ENSP00000349436 |
About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
SNX9 for ontologies About GeneDecksing
|
Drugs & Compounds
for SNX9 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SNX9 for compounds About GeneDecksing
 Browse Tocris compounds for SNX9
1 Novoseek chemical compound relationship for SNX9 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tyrosine |
6.69 |
11 |
16316319 (3), 11799118 (2), 16137687 (1) |
Search CenterWatch for drugs/clinical trials and news about SNX9
|
Transcripts
for SNX9 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SNX9 gene: NM_016224.3 Unigene Cluster for SNX9: Sorting nexin 9 Hs.191213 [show with all ESTs]Unigene Representative Sequence: AB2097363 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000392185(uc003qqv.1) ENST00000539592 ENST00000252631
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SNX9 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SNX9
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SNX9 (NM_016224) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SNX9 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNX9 |
Additional cDNA sequence: AB209736.1 AF076957.1 AF121859.1 AF131214.1 AF172847.1 AF190158.1 AJ420452.1 AJ420512.1 AK026637.1 AK127345.1 AK314360.1 BC001084.2 BC005022.1 16 DOTS entries: DT.95093204 DT.92434771 DT.91868182 DT.92434756 DT.100826247 DT.100826248 DT.121319387 DT.40126285 DT.100726479 DT.91991058 DT.92434773 DT.97859333 DT.121319340 DT.92434753 DT.86859790 DT.91749225 24/314 AceView cDNA sequences (see all 314): T32773 BQ447996 AA313675 AA446880 AI439264 BU734888 CR624899 AI244405 BM989221 BQ007930 BM997157 AI089544 CB161979 AI373663 CD370944 BM712265 T33708 BQ045358 AA286873 AI221687 AA569890 AA528019 AA864571 BE644871
GeneLoc Exon Structure
|
Expression
for SNX9 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SNX9 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAGAAGCCAA
About this image
See SNX9 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SNX9
SOURCE GeneReport for Unigene cluster: Hs.191213
UniProtKB/Swiss-Prot: SNX9_HUMAN, Q9Y5X1Tissue specificity: Widely expressed, with highest levels in heart and placenta, and lowest levels in thymus andperipheral blood leukocytes
SABiosciences Custom PCR Arrays for SNX9
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SNX9
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNX9 |
Orthologs
for SNX9 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SNX9 gene from 6/21 species (see all 21) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
SNX91 |
sorting nexin 9 |
80.65(n)
86.29(a) |
|
421654 XM_419693.3 XP_419693.2 |
lizard
(Anolis carolinensis) |
Reptilia |
SNX96 |
-- |
82(a) |
1 ↔ 1 |
1(213108964-213143653) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.187022 |
Xenopus laevis transcribed sequence with moderate similarity more |
80.23(n) |
|
BI443849.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
570939902 |
-- |
72.53(n) |
|
57093990 |
fruit fly
(Drosophila melanogaster) |
Insecta |
SH3PX13 |
intracellular protein transport |
32(a) |
|
67C5 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
lst-46 |
Lateral Signaling Target family member (lst-4) |
24(a) |
1 → many |
IV(14060980-14069831) |
ENSEMBL Gene Tree for SNX9 (if available)
TreeFam Gene Tree for SNX9 (if available) |
Paralogs
for SNX9 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SNX9 gene
- SNX332 SNX182
4 SIMAP similar genes for SNX9 using alignment to 2 protein entries: SNX9_HUMAN (see all proteins):WISP SH3GL2 SNX33 SNX18
SNX9 for paralogs About GeneDecksing
|
Genomic Variants
for SNX9 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SNX9 (158244281 - 158366109 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for SNX9
1 CNV: 51832 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SNX9 |
|
Disorders
/ Diseases
for SNX9 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SNX9 for disorders About GeneDecksing
OMIM gene information: 605952
OMIM disorders: --
6  diseases for SNX9: About MalaCardswiskott-aldrich syndrome choanal atresia rabies asthma
neuronitis alcoholism
1 Novoseek disease relationship for SNX9 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| wiskott-aldrich syndrome |
66.6 |
3 |
17242350 (1), 17220534 (1), 20427313 (1) |
Human Genome Epidemiology (HuGE) Navigator: SNX9 (2 documents)
Export disorders for SNX9 gene to outside databases
|
Publications
for SNX9 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SNX9 gene, integrated from 9 sources (see all 52):
(articles sorted by number of sources associating them with SNX9) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- SNX9 couples actin assembly to phosphoinositide signals and is required for membrane remodeling during endocytosis. (PubMed id 17609109)1, 2, 3, 9 Yarar D....Schmid S.L. (2007)
- Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1. (PubMed id 10531379)1, 2, 3 Howard L.... Blobel C.P. (1999)
- The Cdc42 target ACK2 interacts with sorting nexin 9 (SH3PX1) to regulate epidermal growth factor receptor degradation. (PubMed id 11799118)1, 2, 9 Lin Q....Yang W. (2002)
- Sorting nexin 9 participates in clathrin-mediated endocytosis through interactions with the core components. (PubMed id 12952949)1, 2, 9 Lundmark R. and Carlsson S.R. (2003)
- Mechanism of aldolase control of sorting nexin 9 func tion in endocytosis. (PubMed id 20129922)1, 2, 9 Rangarajan E.S....Izard T. (2010)
- SNX9 regulates tubular invagination of the plasma membrane through interaction with actin cytoskeleton and dynamin 2. (PubMed id 18388313)1, 2, 9 Shin N....Chang S. (2008)
- Dimerization is required for SH3PX1 tyrosine phosphorylation in response to epidermal growth factor signalling and interaction with ACK2. (PubMed id 16316319)1, 2, 9 Childress C....Yang W. (2006)
- SNX9 as an adaptor for linking synaptojanin-1 to the Cdc42 effector ACK1. (PubMed id 16137687)1, 2, 9 Yeow-Fong L....Manser E. (2005)
- SNX9 regulates dynamin assembly and is required for e fficient clathrin-mediated endocytosis. (PubMed id 15703209)1, 2, 9 Soulet F....Schmid S.L. (2005)
- Structure and plasticity of Endophilin and Sorting Nexin 9. (PubMed id 18940612)1, 2, 9 Wang Q....Sondermann H. (2008)
|
External Searches for SNX9 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SNX9 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SNX9 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SNX9 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SNX9 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SNX9 gene:
Search GeneIP for patents involving SNX9
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SNX9 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | OriGene Antibodies for SNX9 | | OriGene shRNA RFP for SNX9 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SNX9 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SNX9 | | | OriGene Protein Over-expression Lysate for SNX9 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SNX9 | | OriGene 3'-UTR Clone for SNX9 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SNX9 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SNX9 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for SNX9 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SNX9 | | OriGene Custom Protein Services for SNX9 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SNX9 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SNX9 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SNX9 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SNX9 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SNX9 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SNX9 |
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| | | | Search Tocris compounds for SNX9 |
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 | | | SNX9 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNX9 |
|  |  |  | | | | ThermoFisher Antibodies for SNX9 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNX9 |
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