Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

SNX7 Gene

protein-coding GIFtS: 51
GCID: GC01P099127

sorting nexin 7

Explore 6 diseases affiliated with
SNX7 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Sorting Nexin 7¹ ²
Sorting Nexin-7²

External Ids:	HGNC: 14971¹	Entrez Gene: 51375²	Ensembl: ENSG00000162627⁷	OMIM: 614904⁵	UniProtKB: Q9UNH6³

ORGUL members:
	NONCODE:n409354

Export aliases for SNX7 gene to outside databases

Previous GC identifers: GC01P099924 GC01P098252 GC01P098418 GC01P098590 GC01P098839 GC01P097250

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SNX7:

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a

phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled

coil region like some family members, and its exact function is unknown. Alternative splicing results in multiple

transcript variants. A related pseudogene has been identified on chromosome 11. (provided by RefSeq, Jun 2010)

UniProtKB/Swiss-Prot: SNX7_HUMAN, Q9UNH6

Function: May be involved in several stages of intracellular trafficking

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_032977.9

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the SNX7 gene promoter:
TBP Sp1 p300 AP-2gamma MEF-2A SEF-1 (1) AP-2beta aMEF-2 AP-2alpha AP-2alphaA
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SNX7 promoter sequence

Search SABiosciences Chromatin IP Primers for SNX7

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SNX7

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p21.3 Ensembl cytogenetic band: 1p21.3 HGNC cytogenetic band: 1p21

SNX7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SNX7 gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01P099127: view genomic region (about GC identifiers)

Start:	99,127,236 bp from pter	End:	99,226,056 bp from pter
Size:	98,821 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SNX7_HUMAN, Q9UNH6 (See protein sequence)

Recommended Name: Sorting nexin-7

Size: 387 amino acids; 45303 Da

Subcellular location: Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (By similarity)

Sequence caution: Sequence=AAD27830.1; Type=Erroneous initiation; Note=Translation N-terminally extended;

Sequence=BAD96949.1; Type=Erroneous initiation; Note=Translation N-terminally extended;

1 PDB 3D structure from and Proteopedia for SNX7:

3IQ2 (3D)

Secondary accessions: A8KAF3 D3DT50 Q53FQ3 Q5VT09 Q5VT10 Q86U82 Q8WVD4 Q96FW9 Q9Y3Z7

Alternative splicing: 3 isoforms: Q9UNH6-1 Q9UNH6-2 Q9UNH6-3

Explore the universe of human proteins at neXtProt for SNX7: NX_Q9UNH6

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9UNH6

SNX7 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_057060.2 NP_689424.2

ENSEMBL proteins:

ENSP00000434731 ENSP00000304429 ENSP00000435172 ENSP00000388266 ENSP00000359208

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: SNX7 OriGene Protein Over-expression Lysate (see all 2): SNX7 OriGene Custom Protein Services for SNX7
	GenScript Custom Purified and Recombinant Proteins Services for SNX7
	Novus Biologicals SNX7 Proteins Novus Biologicals SNX7 Lysates
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for SNX7

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0030659	cytoplasmic vesicle membrane	IEA	--

SNX7 for ontologies About GeneDecksing

SNX7 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for SNX7
	GenScript Custom Superior Antibodies Services for SNX7
	Novus Biologicals SNX7 Antibodies
	Search for Antibodies for SNX7 at Abcam
	Uscn Antibodies for SNX7
	Search ThermoFisher Antibodies for SNX7

Assay Products for SNX7:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for SNX7
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for SNX7

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

SNX7 for domains About GeneDecksing

1 InterPro domain/family:

IPR001683 Phox

Graphical View of Domain Structure for InterPro Entry Q9UNH6

ProtoNet protein and cluster: Q9UNH6

1 Blocks protein family: IPB001683 Phox-like

UniProtKB/Swiss-Prot: SNX7_HUMAN, Q9UNH6

Similarity: Belongs to the sorting nexin family

Similarity: Contains 1 PX (phox homology) domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: SNX7_HUMAN, Q9UNH6

Function: May be involved in several stages of intracellular trafficking

miRNA Products:		OriGene 3'-UTR Clone (see all 2): SNX7 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SNX7
		5 QIAGEN miScript miRNA Assays for microRNAs that regulate SNX7:
		hsa-miR-9 hsa-miR-659 hsa-miR-3658 hsa-miR-525-5p hsa-miR-520a-5p
		SwitchGear 3'UTR luciferase reporter plasmid: SNX7 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SNX7 (see all 7) OriGene shRNA RFP: SNX7 OriGene siRNA: SNX7
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SNX7

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for SNX7

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SNX7 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SNX7 (see all 4) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): SNX7 (NM_015976)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SNX7
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNX7

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for SNX7
		Search LifeMap BioReagents cell lines for SNX7

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNX7

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0035091	phosphatidylinositol binding	IEA	--

SNX7 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for SNX7

STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

5/11 Interacting proteins for SNX7 (Q9UNH6^{2, 3} ENSP00000304429⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 11)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TEX11	Q8IYF3²^,³, ENSP00000340995⁴	MINT-68351 I2D: score=5 STRING: ENSP00000340995
HMOX2	P30519²^,³	MINT-8258434 I2D: score=2
MEST	Q5EB52²^,³	MINT-8262983 I2D: score=1
MAGEA11	P43364²^,³, ENSP00000347358⁴	MINT-68119 I2D: score=5 STRING: ENSP00000347358
CRK	P46108³, ENSP00000300574⁴	I2D: score=1 STRING: ENSP00000300574

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007154	cell communication	IEA	--
GO:0015031	protein transport	IEA	--

SNX7 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SNX7
Search CenterWatch for drugs/clinical trials and news about SNX7

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for SNX7 gene (2 alternative transcripts):

NM_015976.4 NM_152238.3

Unigene Cluster for SNX7:

Sorting nexin 7

Hs.197015 [show with all ESTs]

Unigene Representative Sequence: NM_015976

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000529992(uc010oud.2) ENST00000306121(uc010ouc.2) ENST00000473868

ENST00000528824 ENST00000454199 ENST00000370189(uc001dsa.3)

miRNA Products:		OriGene 3'-UTR Clone (see all 2): SNX7 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SNX7
		5 QIAGEN miScript miRNA Assays for microRNAs that regulate SNX7:
		hsa-miR-9 hsa-miR-659 hsa-miR-3658 hsa-miR-525-5p hsa-miR-520a-5p
		SwitchGear 3'UTR luciferase reporter plasmid: SNX7 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SNX7 (see all 7) OriGene shRNA RFP: SNX7 OriGene siRNA: SNX7
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SNX7

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SNX7 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SNX7 (see all 4) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): SNX7 (NM_015976)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SNX7
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNX7

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SNX7 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat SNX7
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SNX7
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SNX7

Additional cDNA sequence:

AF121857.1 AK025031.1 AK223229.1 AK293018.1 AK298211.1 AL049989.1 BC010349.1 BC018105.1

BT006747.1 NR_033716.1

3 DOTS entries:

DT.307389 DT.100784876 DT.95168361

24/141 AceView cDNA sequences (see all 141):

BM798146 AI537337 NM_152238 T05567 AA082796 BE380040 NM_015976 BU615287

BC018105 BE885333 CK819639 R58514 BM129423 CR597164 CR610212 BQ422856

BM784001 BE884475 BM467851 BQ233434 BE811434 AF121857 BF215618 BM970720

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for SNX7 About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10
SP1:					-
SP2:																			-

ECgene alternative splicing isoforms for SNX7

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

SNX7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCATTTTAAA

About this image

SNX7 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Eye

Inner Nuclear Layer

Mature Horizontal Cells

Horizontal, Retina

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See SNX7 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SNX7

SOURCE GeneReport for Unigene cluster: Hs.197015

SABiosciences Custom PCR Arrays for SNX7

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SNX7 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat SNX7
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SNX7
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SNX7

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNX7

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for SNX7 gene from 7/24 species (see all 24) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	SNX7¹	sorting nexin 7	76.98(n) 77.58(a)		424478 XM_422321.2 XP_422321.1
lizard (Anolis carolinensis)	Reptilia	SNX7⁶	--	75(a)	1 ↔ 1	4(92683396-92696680)
African clawed frog (Xenopus laevis)	Amphibia	Xl.6955²	Xenopus laevis transcribed sequence with moderate similarity more	74.98(n)		CA982875.1
zebrafish (Danio rerio)	Actinopterygii	Dr.13759²	Transcribed sequence with weak similarity to protein more	72.84(n)		CK025940.1
honey bee (Apis mellifera)	Insecta	--	--	28(a)	1 → many	Group8.19(1168-3316)
thale cress (Arabidopsis thaliana)	eudicotyledons	SNX1⁶	sorting nexin 1	20(a)	possible ortholog	5(1856008-1858785)
rice (Oryza sativa)	Liliopsida	--	sorting nexin 1, putative, expressed	23(a)	possible ortholog	1(37314248-37319474)

ENSEMBL Gene Tree for SNX7 (if available)
TreeFam Gene Tree for SNX7 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for SNX7 gene

SNX30² SNX4²

2 SIMAP similar genes for SNX7 using alignment to 4 protein entries: SNX7_HUMAN (see all proteins):

SNX30 SNX2

SNX7 for paralogs About GeneDecksing

2 Pseudogenes.org Pseudogenes for SNX7
PGOHUM00000242469 PGOHUM00000242470

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs11166062^1,2	C,F,A,H,	--	99125357(+)	`TTCTTG/CTTTTT`	3	--	us2k¹		6		NS EA WA	532
rs189571660^1,2		--	99125425(+)	`TTCCAG/TGAAAC`	3	--	us2k¹		0	--	--	--	--
rs144121749^1,2		--	99125562(+)	`GGTACG/TGCTGC`	3	--	us2k¹		0	--	--	--	--
rs114990430^1,2	F,	--	99125613(+)	`ACAATA/GTTGAC`	3	--	us2k¹		1		WA	118
rs11166063^1,2	C,F,A,H,	--	99125640(+)	`TGGCAA/TCCAGT`	3	--	us2k¹		9		NS EA NA WA CSA	542
rs78137486^1,2	F,	--	99125746(+)	`TTTTCT/CGAGCC`	3	--	us2k¹		1		NA	120
rs181623903^1,2		--	99125764(+)	`TATGGA/TTTCTA`	3	--	us2k¹		0	--	--	--	--
rs145996849^1,2		--	99125906(+)	`TTACAG/TAAATT`	3	--	us2k¹		0	--	--	--	--
rs12086863^1,2	C,F,A,	--	99125968(+)	`GATCCT/CCAACC`	3	--	us2k¹		3		WA CSA	122
rs186067440^1,2		--	99126141(+)	`GATGGC/TATTTA`	3	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for SNX7 (99127236 - 99226056 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SNX7: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SNX7

DNA2.0 Custom Variant and Variant Library Synthesis for SNX7

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

SNX7 for disorders           About GeneDecksing

OMIM gene information: 614904    OMIM disorders: --

6 diseases for SNX7:    About MalaCards

hiatus hernia spastic paraplegia hereditary spastic paraplegia paraplegia

spasticity hernia

1 disease from the University of Copenhagen DISEASES database for SNX7:

Hiatus hernia

Export disorders for SNX7 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for SNX7 gene, integrated from 9 sources (see all 16):
(articles sorted by number of sources associating them with SNX7)

Utopia: connect your pdf to the dynamic
world of online information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
A large family of endosome-localized proteins related to sorting nexin 1. (PubMed id 11485546)^{1, 2} Teasdale R.D.... Gleeson P.A. (2001)
New locus for hereditary spastic paraplegia maps to chromosome 1p31.1-1p21.1. (PubMed id 16130112)^{1, 9} Orlacchio A....Bernardi G. (2005)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
Genome-wide association identifies nine common variant s associated with fasting proinsulin levels and provides new insights into the p athophysiology of type 2 diabetes. (PubMed id 21873549)¹ Strawbridge R.J....Florez J.C. (2011)
A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)¹ Vinayagam A....Wanker E.E. (2011)
Do GnRH analogues directly affect human endometrial e pithelial cell gene expression? (PubMed id 20203127)¹ Zhang X....Oehninger S. (2010)
Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. (PubMed id 17474147)¹ Wu C....Li S.S. (2007)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)² Gregory S.G.... Bentley D.R. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 51375	HGNC: 14971	AceView: SNX7	Ensembl:ENSG00000162627	euGenes: HUgn51375
ECgene: SNX7	H-InvDB: SNX7

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for SNX7	Pharmacogenomics, SNPs, Pathways

Intellectual Property for SNX7 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for SNX7 gene:
Search GeneIP for patents involving SNX7

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for SNX7
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SNX7		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SNX7
	OriGene Protein Over-expression Lysate for SNX7		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for SNX7		OriGene 3'-UTR Clone for SNX7
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SNX7		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SNX7
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	OriGene Purified Protein for SNX7		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for SNX7		OriGene Custom Protein Services for SNX7
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SNX7
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SNX7
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SNX7
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SNX7
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SNX7
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SNX7

	GenScript Custom Purified and Recombinant Proteins Services for SNX7		GenScript cDNA clones with any tag delivered in your preferred vector for SNX7
	GenScript Custom Assay Services for SNX7		GenScript Custom Superior Antibodies Services for SNX7
	GenScript Custom overexpressing Cell Line Services for SNX7		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in SNX7 promoter
	Search Chromatin IP Primers for SNX7
	RT² qPCR Primer Assay in human, mouse, rat SNX7
	Search GNC Networks for SNX7
	SABiosciences Custom PCR Arrays for SNX7

Search Tocris compounds for SNX7

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	SNX7 antibodies
	SNX7 proteins
	SNX7 lysates

	Search for Antibodies for SNX7 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for SNX7
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

SNX7 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for SNX7

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNX7

	SwitchGear 3'UTR luciferase reporter plasmids for SNX7
	SwitchGear Promoter luciferase reporter plasmids for SNX7

Search ThermoFisher Antibodies for SNX7

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNX7

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes SNX7 gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4

Advanced Search

Export list of displayed genes

SNX7 Gene

sorting nexin 7

Aliases
for SNX7 gene

Summaries
for SNX7 gene

Genomic Views
for SNX7 gene

Proteins
for SNX7 gene

Protein Domains /
Families
for SNX7 gene

Function
for SNX7 gene

Pathways & Interactions
for SNX7 gene

Drugs & Compounds
for SNX7 gene

Transcripts
for SNX7 gene

Expression
for SNX7 gene

Orthologs
for SNX7 gene

Paralogs
for SNX7 gene

Genomic Variants
for SNX7 gene

Disorders / Diseases
for SNX7 gene

Publications
for SNX7 gene

External Searches for SNX7 gene

Genome Databases showing SNX7 gene

Other Databases showing SNX7 gene

Specialized Databases showing SNX7 gene

Intellectual Property
for SNX7 gene

Products
for SNX7 gene

View Random Gene

Advanced Search

Export list of displayed genes

SNX7 Gene

sorting nexin 7

Aliasesfor SNX7 gene

Summariesfor SNX7 gene

Genomic Viewsfor SNX7 gene

Proteinsfor SNX7 gene

Protein Domains /Familiesfor SNX7 gene

Functionfor SNX7 gene

Pathways & Interactionsfor SNX7 gene

Drugs & Compoundsfor SNX7 gene

Transcriptsfor SNX7 gene

Expression for SNX7 gene

Orthologsfor SNX7 gene

Paralogsfor SNX7 gene

Genomic Variantsfor SNX7 gene

Disorders / Diseasesfor SNX7 gene

Publicationsfor SNX7 gene

External Searches for SNX7 gene

Genome Databases showing SNX7 gene

Other Databases showing SNX7 gene

Specialized Databases showing SNX7 gene

Intellectual Propertyfor SNX7 gene

Productsfor SNX7 gene

View Random Gene

Aliases
for SNX7 gene

Summaries
for SNX7 gene

Genomic Views
for SNX7 gene

Proteins
for SNX7 gene

Protein Domains /
Families
for SNX7 gene

Function
for SNX7 gene

Pathways & Interactions
for SNX7 gene

Drugs & Compounds
for SNX7 gene

Transcripts
for SNX7 gene

Expression
for SNX7 gene

Orthologs
for SNX7 gene

Paralogs
for SNX7 gene

Genomic Variants
for SNX7 gene

Disorders / Diseases
for SNX7 gene

Publications
for SNX7 gene

Intellectual Property
for SNX7 gene

Products
for SNX7 gene