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SNX7 Gene

protein-coding   GIFtS: 54
GCID: GC01P099127

Sorting Nexin 7

  See SNX7-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Sorting Nexin 71 2
Sorting Nexin-72

External Ids:    HGNC: 149711   Entrez Gene: 513752   Ensembl: ENSG000001626277   OMIM: 6149045   UniProtKB: Q9UNH63   

Export aliases for SNX7 gene to outside databases

Previous GC identifers: GC01P099924 GC01P098252 GC01P098418 GC01P098590 GC01P098839 GC01P097250


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SNX7 Gene:
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which
is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not
contain a coiled coil region like some family members, and its exact function is unknown. Alternative splicing
results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. (provided by
RefSeq, Jun 2010)

GeneCards Summary for SNX7 Gene:
SNX7 (sorting nexin 7) is a protein-coding gene. Diseases associated with SNX7 include hiatus hernia. GO annotations related to this gene include phosphatidylinositol binding. An important paralog of this gene is SNX30.

UniProtKB/Swiss-Prot: SNX7_HUMAN, Q9UNH6
Function: May be involved in several stages of intracellular trafficking




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_032977.10  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SNX7 gene promoter:
         TBP   Sp1   p300   AP-2gamma   MEF-2A   SEF-1 (1)   AP-2beta   aMEF-2   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSNX7 promoter sequence
   Search Chromatin IP Primers for SNX7

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SNX7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p21.3   Ensembl cytogenetic band:  1p21.3   HGNC cytogenetic band: 1p21

SNX7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SNX7 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P099127:  view genomic region     (about GC identifiers)

Start:
99,127,236 bp from pter      End:
99,226,056 bp from pter
Size:
98,821 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SNX7_HUMAN, Q9UNH6 (See protein sequence)
Recommended Name: Sorting nexin-7  
Size: 387 amino acids; 45303 Da
Sequence caution: Sequence=AAD27830.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAD96949.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
1 PDB 3D structure from and Proteopedia for SNX7:
3IQ2 (3D)    
Secondary accessions: A8KAF3 D3DT50 Q53FQ3 Q5VT09 Q5VT10 Q86U82 Q8WVD4 Q96FW9 Q9Y3Z7
Alternative splicing: 3 isoforms:  Q9UNH6-1   Q9UNH6-2   Q9UNH6-3   

Explore the universe of human proteins at neXtProt for SNX7: NX_Q9UNH6

Explore proteomics data for SNX7 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SNX7 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_057060.2  NP_689424.2  

    ENSEMBL proteins: 
     ENSP00000434731   ENSP00000304429   ENSP00000435172   ENSP00000388266   ENSP00000359208  

    SNX7 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SNX: Sorting nexins

    2 InterPro protein domains:
     IPR001683 Phox
     IPR028656 SNX7

    Graphical View of Domain Structure for InterPro Entry Q9UNH6

    ProtoNet protein and cluster: Q9UNH6

    1 Blocks protein domain: IPB001683 Phox-like

    UniProtKB/Swiss-Prot: SNX7_HUMAN, Q9UNH6
    Similarity: Belongs to the sorting nexin family
    Similarity: Contains 1 PX (phox homology) domain


    Find genes that share domains with SNX7           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SNX7_HUMAN, Q9UNH6
    Function: May be involved in several stages of intracellular trafficking

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0035091phosphatidylinositol binding IBA--
         
    Find genes that share ontologies with SNX7           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SNX7
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SNX7
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    miRNA
    Products:
        
    miRTarBase miRNAs that target SNX7:
    hsa-mir-132-3p (MIRT021836), hsa-mir-9-5p (MIRT021387), hsa-mir-324-5p (MIRT043181), hsa-mir-96-5p (MIRT048715), hsa-mir-124-3p (MIRT022637)

    Block miRNA regulation of human, mouse, rat SNX7 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate SNX7:
    hsa-miR-9 hsa-miR-659 hsa-miR-3658 hsa-miR-525-5p hsa-miR-520a-5p
    SwitchGear 3'UTR luciferase reporter plasmidSNX7 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SNX7

    Gene Editing
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    Sino Biological Human cDNA Clone for SNX7
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNX7

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNX7


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SNX7_HUMAN, Q9UNH6: Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005768endosome IBA--
    GO:0030659cytoplasmic vesicle membrane IEA--

    Find genes that share ontologies with SNX7           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SNX7
    Interactions:

        Search GeneGlobe Interaction Network for SNX7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for SNX7 (Q9UNH61, 2, 3 ENSP000003044294) via UniProtKB, MINT, STRING, and/or I2D (see all 48)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TEX11Q8IYF32, 3, ENSP000003409954MINT-68351 I2D: score=5 STRING: ENSP00000340995
    HMOX2P305192, 3MINT-8258434 I2D: score=2 
    MESTQ5EB522, 3MINT-8262983 I2D: score=1 
    MAGEA11P433642, 3, ENSP000003473584MINT-68119 I2D: score=5 STRING: ENSP00000347358
    CRKP461083, ENSP000003005744I2D: score=1 STRING: ENSP00000300574
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    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006886intracellular protein transport IBA--
    GO:0006915apoptotic process IBA--
    GO:0007154cell communication ----
    GO:0015031protein transport ----

    Find genes that share ontologies with SNX7           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SNX7



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SNX7 gene (2 alternative transcripts): 
    NM_015976.4  NM_152238.3  

    Unigene Cluster for SNX7:

    Sorting nexin 7
    Hs.197015  [show with all ESTs]
    Unigene Representative Sequence: NM_015976
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000529992(uc010oud.2) ENST00000306121(uc010ouc.2) ENST00000473868
    ENST00000528824 ENST00000454199 ENST00000370189(uc001dsa.3)
    miRNA
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    5 qRT-PCR Assays for microRNAs that regulate SNX7:
    hsa-miR-9 hsa-miR-659 hsa-miR-3658 hsa-miR-525-5p hsa-miR-520a-5p
    SwitchGear 3'UTR luciferase reporter plasmidSNX7 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SNX7
    Predesigned siRNA for gene silencing in human, mouse, rat SNX7
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    GenScript: all cDNA clones in your preferred vector (see all 2): SNX7 (NM_015976)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SNX7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNX7
    Primer
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    OriGene qPCR primer pairs and template standards for SNX7
    OriGene qSTAR qPCR primer pairs in human, mouse for SNX7
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SNX7
      QuantiTect SYBR Green Assays in human, mouse, rat SNX7
      QuantiFast Probe-based Assays in human, mouse, rat SNX7

    Additional mRNA sequence: 

    AF121857.1 AK025031.1 AK223229.1 AK293018.1 AK298211.1 AL049989.1 BC010349.1 BC018105.1 
    BT006747.1 NR_033716.1 

    3 DOTS entries:

    DT.307389  DT.100784876  DT.95168361 

    Selected AceView cDNA sequences (see all 141):

    CK819639 R58514 BM129423 CR610212 CR597164 AI537337 BM798146 BE885333 
    NM_152238 BC018105 T05567 AA082796 BE380040 NM_015976 BU615287 BE883038 
    BE883124 BE379616 BG212834 BQ017777 AL548028 BE501975 BG573420 BU686970 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for SNX7    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10
    SP1:              -                                                   
    SP2:                                                        -         


    ECgene alternative splicing isoforms for SNX7

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SNX7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCATTTTAAA
    SNX7 Expression
    About this image


    SNX7 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Neurons
             Mature Horizontal Cells Inner Nuclear Layer
     
     Eye (Sensory Organs)
             Mature Horizontal Cells Inner Nuclear Layer
     
     Amnion (Extraembryonic Tissues)
    SNX7 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SNX7 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.197015
        Custom PCR Arrays for SNX7
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNX7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SNX7 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Snx71 , 5 sorting nexin 71, 5 84.76(n)1
    90.09(a)1
      3 (51.21 cM)5
    765611  NM_029655.31  NP_083931.21 
     1177814975 
    chicken
    (Gallus gallus)
    Aves SNX71 sorting nexin 7 76.98(n)
    77.58(a)
      424478  XM_422321.3  XP_422321.1 
    lizard
    (Anolis carolinensis)
    Reptilia SNX76
    sorting nexin 7
    66(a)
    1 ↔ 1
    4(92664046-92729389)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.69552 Xenopus laevis transcribed sequence with moderate similarity more 74.98(n)    CA982875.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.137592 Transcribed sequence with weak similarity to protein more 72.84(n)    CK025940.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SNX46
    Sorting nexin, involved in retrieval of late-Golgi...
    21(a)
    1 → many
    X(378825-380096) YJL036W


    ENSEMBL Gene Tree for SNX7 (if available)
    TreeFam Gene Tree for SNX7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SNX7 gene
    SNX302  SNX22  SNX12  SNX42  
    2 SIMAP similar genes for SNX7 using alignment to 4 protein entries:     SNX7_HUMAN (see all proteins):
    SNX30    SNX2

    Find genes that share paralogs with SNX7           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for SNX7
    PGOHUM00000242469 PGOHUM00000242470


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SNX7 (see all 1952)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs111660621,2
    C,F,A,H--99125357(+) TTCTTG/CTTTTT 3 -- us2k16Minor allele frequency- C:0.03NS EA WA 532
    rs1895716601,2
    --99125425(+) TTCCAG/TGAAAC 3 -- us2k10--------
    rs1441217491,2
    --99125562(+) GGTACG/TGCTGC 3 -- us2k10--------
    rs1149904301,2
    C,F--99125613(+) ACAATA/GTTGAC 3 -- us2k11Minor allele frequency- G:0.03WA 118
    rs111660631,2
    C,F,A,H--99125640(+) TGGCAA/TCCAGT 3 -- us2k19Minor allele frequency- T:0.03NS EA NA WA CSA 542
    rs781374861,2
    C,F--99125746(+) TTTTCT/CGAGCC 3 -- us2k11Minor allele frequency- C:0.06NA 120
    rs1816239031,2
    --99125764(+) TATGGA/TTTCTA 3 -- us2k10--------
    rs1459968491,2
    --99125906(+) TTACAG/TAAATT 3 -- us2k10--------
    rs120868631,2
    C,F,A--99125968(+) GATCCT/CCAACC 3 -- us2k13Minor allele frequency- C:0.08WA CSA 122
    rs1860674401,2
    --99126141(+) GATGGC/TATTTA 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for SNX7 (99127236 - 99226056 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for SNX7:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2662446CNV Deletion23128226
    esv2715252CNV Deletion23290073
    esv2670043CNV Deletion23128226
    esv2715240CNV Deletion23290073
    nsv830747CNV Loss17160897
    nsv2065CNV Loss18451855
    nsv830760CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SNX7
    DNA2.0 Custom Variant and Variant Library Synthesis for SNX7

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 614904    OMIM disorders: --

    1 disease for SNX7:    
    About MalaCards
    hiatus hernia

    1 disease from the University of Copenhagen DISEASES database for SNX7:
    Hiatus hernia

    Find genes that share disorders with SNX7           About GenesLikeMe

    Genetic Association Database (GAD): SNX7

    Export disorders for SNX7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SNX7 gene, integrated from 10 sources (see all 20):
    (articles sorted by number of sources associating them with SNX7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes. (PubMed id 21873549)1, 4 Strawbridge R.J....Florez J.C. (Diabetes 2011)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. A large family of endosome-localized proteins related to sorting nexin 1. (PubMed id 11485546)1, 2 Teasdale R.D.... Gleeson P.A. (Biochem. J. 2001)
    4. New locus for hereditary spastic paraplegia maps to chromosome 1p31.1-1p21.1. (PubMed id 16130112)1, 9 Orlacchio A....Bernardi G. (Ann. Neurol. 2005)
    5. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    6. Genome-wide association scan of dental caries in the permanent dentition. (PubMed id 23259602)1 Wang X....Marazita M.L. (BMC Oral Health 2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    8. A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (Sci Signal 2011)
    9. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    10. Do GnRH analogues directly affect human endometrial epithelial cell gene expression? (PubMed id 20203127)1 Zhang X....Oehninger S. (Mol. Hum. Reprod. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51375 HGNC: 14971 AceView: SNX7 Ensembl:ENSG00000162627 euGenes: HUgn51375
    ECgene: SNX7 H-InvDB: SNX7

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SNX7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SNX7 gene:
    Search GeneIP for patents involving SNX7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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