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Aliases for SNX32 Gene

Aliases for SNX32 Gene

  • Sorting Nexin 32 2 3
  • Sorting Nexin 6B 2 3
  • Sorting Nexin-6B 3 4
  • SNX6B 3 4
  • Sorting Nexin-32 3

External Ids for SNX32 Gene

Previous HGNC Symbols for SNX32 Gene

  • SNX6B

Previous GeneCards Identifiers for SNX32 Gene

  • GC11P065357
  • GC11P065601
  • GC11P061927

Summaries for SNX32 Gene

GeneCards Summary for SNX32 Gene

SNX32 (Sorting Nexin 32) is a Protein Coding gene. GO annotations related to this gene include phosphatidylinositol binding. An important paralog of this gene is SNX5.

UniProtKB/Swiss-Prot for SNX32 Gene

  • May be involved in several stages of intracellular trafficking.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNX32 Gene

Genomics for SNX32 Gene

Regulatory Elements for SNX32 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SNX32 Gene

Start:
65,833,641 bp from pter
End:
65,856,896 bp from pter
Size:
23,256 bases
Orientation:
Plus strand

Genomic View for SNX32 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SNX32 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNX32 Gene

Proteins for SNX32 Gene

  • Protein details for SNX32 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86XE0-SNX32_HUMAN
    Recommended name:
    Sorting nexin-32
    Protein Accession:
    Q86XE0
    Secondary Accessions:
    • Q8IW53
    • Q96NG4

    Protein attributes for SNX32 Gene

    Size:
    403 amino acids
    Molecular mass:
    46399 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SNX32 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SNX32 Gene

Proteomics data for SNX32 Gene at MOPED

Post-translational modifications for SNX32 Gene

  • Ubiquitination at Lys132
  • Modification sites at PhosphoSitePlus

Other Protein References for SNX32 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SNX32 Gene

Domains for SNX32 Gene

Gene Families for SNX32 Gene

HGNC:
  • SNX :Sorting nexins

Protein Domains for SNX32 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for SNX32 Gene

Graphical View of Domain Structure for InterPro Entry

Q86XE0

UniProtKB/Swiss-Prot:

SNX32_HUMAN :
  • Q86XE0
Domain:
  • Contains 1 PX (phox homology) domain.
Family:
  • Belongs to the sorting nexin family.
genes like me logo Genes that share domains with SNX32: view

Function for SNX32 Gene

Molecular function for SNX32 Gene

UniProtKB/Swiss-Prot Function: May be involved in several stages of intracellular trafficking.

Gene Ontology (GO) - Molecular Function for SNX32 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 21516116
GO:0035091 phosphatidylinositol binding IBA --
genes like me logo Genes that share ontologies with SNX32: view

Animal Model Products

CRISPR Products

miRNA for SNX32 Gene

miRTarBase miRNAs that target SNX32

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SNX32

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for SNX32 Gene

Localization for SNX32 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SNX32 Gene COMPARTMENTS Subcellular localization image for SNX32 gene
Compartment Confidence
cytosol 3
nucleus 2

Gene Ontology (GO) - Cellular Components for SNX32 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005768 endosome IBA --
GO:0019898 extrinsic component of membrane IBA --
genes like me logo Genes that share ontologies with SNX32: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for SNX32 Gene

Pathways for SNX32 Gene

SuperPathways for SNX32 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SNX32 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006886 intracellular protein transport --
GO:0006897 endocytosis IBA --
GO:0015031 protein transport IEA --
GO:0016050 vesicle organization IBA --
genes like me logo Genes that share ontologies with SNX32: view

No data available for Pathways by source for SNX32 Gene

Transcripts for SNX32 Gene

Unigene Clusters for SNX32 Gene

Sorting nexin 32:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SNX32

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for SNX32

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNX32 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b · 3c · 3d ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14
SP1: - - - -
SP2: - - - -
SP3: - - -
SP4: - - - -
SP5: - - - -
SP6:
SP7: -

Relevant External Links for SNX32 Gene

GeneLoc Exon Structure for
SNX32
ECgene alternative splicing isoforms for
SNX32

Expression for SNX32 Gene

mRNA expression in normal human tissues for SNX32 Gene

mRNA differential expression in normal tissues according to GTEx for SNX32 Gene

This gene is overexpressed in Brain - Cortex (6.9), Brain - Nucleus accumbens (basal ganglia) (6.0), Brain - Caudate (basal ganglia) (5.3), Brain - Frontal Cortex (BA9) (5.2), Brain - Putamen (basal ganglia) (5.1), and Brain - Anterior cingulate cortex (BA24) (4.6).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for SNX32 Gene

SOURCE GeneReport for Unigene cluster for SNX32 Gene Hs.591950

genes like me logo Genes that share expressions with SNX32: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for SNX32 Gene

Orthologs for SNX32 Gene

This gene was present in the common ancestor of animals.

Orthologs for SNX32 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNX32 35
  • 99.17 (n)
  • 99.75 (a)
SNX32 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SNX32 36
  • 56 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SNX32 35
  • 89.45 (n)
  • 93.97 (a)
SNX32 36
  • 92 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Snx32 35
  • 87.06 (n)
  • 91.29 (a)
Snx32 16
Snx32 36
  • 91 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SNX32 36
  • 88 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SNX32 36
  • 55 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Snx32 35
  • 84.25 (n)
  • 86.82 (a)
zebrafish
(Danio rerio)
Actinopterygii si:dkey-28n18.9 36
  • 22 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta Snx6 36
  • 47 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea snx-6 36
  • 40 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.5377 36
  • 46 (a)
OneToMany
Species with no ortholog for SNX32:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for SNX32 Gene

ENSEMBL:
Gene Tree for SNX32 (if available)
TreeFam:
Gene Tree for SNX32 (if available)

Paralogs for SNX32 Gene

Paralogs for SNX32 Gene

Selected SIMAP similar genes for SNX32 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SNX32: view

Variants for SNX32 Gene

Sequence variations from dbSNP and Humsavar for SNX32 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs473661 -- 65,848,972(+) AACCC(C/T)GTCTC intron-variant
rs577597 -- 65,844,295(+) agacc(A/C)atgga intron-variant
rs577630 -- 65,844,312(+) AGTCC(A/C)AAGTT intron-variant
rs578394 -- 65,844,363(+) CAGCT(C/T)TCAGC intron-variant
rs592956 -- 65,840,929(+) ATTAT(A/G)GGTtt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SNX32 Gene

Variant ID Type Subtype PubMed ID
nsv897736 CNV Loss 21882294
dgv393e1 CNV Complex 17122850
dgv1185n71 CNV Loss 21882294
esv2744633 CNV Deletion 23290073
esv2744634 CNV Deletion 23290073
esv2662850 CNV Deletion 23128226
nsv897763 CNV Loss 21882294
nsv897764 CNV Loss 21882294

Relevant External Links for SNX32 Gene

HapMap Linkage Disequilibrium report
SNX32

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SNX32 Gene

Disorders for SNX32 Gene

No disorders were found for SNX32 Gene.

No data available for UniProtKB/Swiss-Prot for SNX32 Gene

Publications for SNX32 Gene

  1. The Phox (PX) domain proteins and membrane traffic. (PMID: 16782399) Seet L.F. … Hong W. (Biochim. Biophys. Acta 2006) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes. (PMID: 15203218) Fu G.K. … Stuve L.L. (Genomics 2004) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3

Products for SNX32 Gene

Sources for SNX32 Gene

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