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Aliases for SNX31 Gene

Aliases for SNX31 Gene

  • Sorting Nexin 31 2 3

External Ids for SNX31 Gene

Previous GeneCards Identifiers for SNX31 Gene

  • GC08M101656
  • GC08M101585
  • GC08M096784

Summaries for SNX31 Gene

GeneCards Summary for SNX31 Gene

SNX31 (Sorting Nexin 31) is a Protein Coding gene. GO annotations related to this gene include phosphatidylinositol binding. An important paralog of this gene is SNX27.

UniProtKB/Swiss-Prot for SNX31 Gene

  • May be involved in protein trafficking.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNX31 Gene

Genomics for SNX31 Gene

Regulatory Elements for SNX31 Gene

Genomic Location for SNX31 Gene

Start:
100,572,882 bp from pter
End:
100,663,415 bp from pter
Size:
90,534 bases
Orientation:
Minus strand

Genomic View for SNX31 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SNX31 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNX31 Gene

Proteins for SNX31 Gene

  • Protein details for SNX31 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N9S9-SNX31_HUMAN
    Recommended name:
    Sorting nexin-31
    Protein Accession:
    Q8N9S9
    Secondary Accessions:
    • C9J6L9
    • Q8N0U9

    Protein attributes for SNX31 Gene

    Size:
    440 amino acids
    Molecular mass:
    50802 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SNX31 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SNX31 Gene

Proteomics data for SNX31 Gene at MOPED

Post-translational modifications for SNX31 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SNX31 Gene

No data available for DME Specific Peptides for SNX31 Gene

Domains for SNX31 Gene

Gene Families for SNX31 Gene

HGNC:
  • SNX :Sorting nexins

Protein Domains for SNX31 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for SNX31 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N9S9

UniProtKB/Swiss-Prot:

SNX31_HUMAN :
  • Q8N9S9
Domain:
  • Contains 1 PX (phox homology) domain.
Family:
  • Belongs to the sorting nexin family.
genes like me logo Genes that share domains with SNX31: view

Function for SNX31 Gene

Molecular function for SNX31 Gene

UniProtKB/Swiss-Prot Function: May be involved in protein trafficking.

Gene Ontology (GO) - Molecular Function for SNX31 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0035091 phosphatidylinositol binding IEA --
genes like me logo Genes that share ontologies with SNX31: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SNX31

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SNX31 Gene

Localization for SNX31 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SNX31 Gene COMPARTMENTS Subcellular localization image for SNX31 gene
Compartment Confidence
cytosol 3
nucleus 2
endoplasmic reticulum 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for SNX31 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005856 cytoskeleton --
GO:0043234 protein complex IEA --
genes like me logo Genes that share ontologies with SNX31: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for SNX31 Gene

Pathways for SNX31 Gene

SuperPathways for SNX31 Gene

No Data Available

Interacting Proteins for SNX31 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000312368%0d%0a9606.ENSP00000304854%0d%0a
Selected Interacting proteins: ENSP00000312368 Q8N9S9-SNX31_HUMAN for SNX31 Gene via STRING UniProtKB

Gene Ontology (GO) - Biological Process for SNX31 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015031 protein transport IEA --
genes like me logo Genes that share ontologies with SNX31: view

No data available for Pathways by source for SNX31 Gene

Transcripts for SNX31 Gene

Unigene Clusters for SNX31 Gene

Sorting nexin 31:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SNX31

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for SNX31
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNX31 Gene

No ASD Table

Relevant External Links for SNX31 Gene

GeneLoc Exon Structure for
SNX31
ECgene alternative splicing isoforms for
SNX31

Expression for SNX31 Gene

mRNA expression in normal human tissues for SNX31 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SNX31 Gene

This gene is overexpressed in Bladder (24.4) and Esophagus - Mucosa (5.6).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for SNX31 Gene

SOURCE GeneReport for Unigene cluster for SNX31 Gene Hs.567758

genes like me logo Genes that share expressions with SNX31: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for SNX31 Gene

Orthologs for SNX31 Gene

This gene was present in the common ancestor of animals.

Orthologs for SNX31 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNX31 35
  • 99.47 (n)
  • 99.32 (a)
SNX31 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SNX31 35
  • 88.13 (n)
  • 84.25 (a)
SNX31 36
  • 85 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SNX31 35
  • 87.95 (n)
  • 83.3 (a)
SNX31 36
  • 81 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Snx31 35
  • 80.37 (n)
  • 75.8 (a)
Snx31 16
Snx31 36
  • 75 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SNX31 36
  • 65 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SNX31 36
  • 74 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Snx31 35
  • 80.33 (n)
  • 74.26 (a)
lizard
(Anolis carolinensis)
Reptilia SNX31 36
  • 60 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.3842 35
tropical clawed frog
(Silurana tropicalis)
Amphibia snx31 35
  • 57.01 (n)
  • 45.33 (a)
Str.20203 35
zebrafish
(Danio rerio)
Actinopterygii snx27b 36
  • 16 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta CG5734 36
  • 26 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea snx-17 36
  • 18 (a)
OneToMany
Species with no ortholog for SNX31:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SNX31 Gene

ENSEMBL:
Gene Tree for SNX31 (if available)
TreeFam:
Gene Tree for SNX31 (if available)

Paralogs for SNX31 Gene

Paralogs for SNX31 Gene

genes like me logo Genes that share paralogs with SNX31: view

Variants for SNX31 Gene

Sequence variations from dbSNP and Humsavar for SNX31 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs1609 -- 100,573,021(+) TTCTA(C/T)ACATA utr-variant-3-prime
rs752036 -- 100,614,013(-) TGTGA(A/G)CCTGG intron-variant
rs872334 -- 100,611,142(+) ACATC(C/T)TTTAG intron-variant
rs950648 -- 100,584,258(-) TTGTG(A/G/T)TGTGA intron-variant
rs1078186 -- 100,613,251(+) TCCAT(C/T)TTAGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SNX31 Gene

Variant ID Type Subtype PubMed ID
nsv527071 CNV Loss 19592680
esv2678325 CNV Deletion 23128226
esv2659653 CNV Deletion 23128226
nsv438073 CNV Loss 16468122

Relevant External Links for SNX31 Gene

HapMap Linkage Disequilibrium report
SNX31
Human Gene Mutation Database (HGMD)
SNX31

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SNX31 Gene

Disorders for SNX31 Gene

Relevant External Links for SNX31

Genetic Association Database (GAD)
SNX31
Human Genome Epidemiology (HuGE) Navigator
SNX31
genes like me logo Genes that share disorders with SNX31: view

No data available for UniProtKB/Swiss-Prot for SNX31 Gene

Publications for SNX31 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The Phox (PX) domain proteins and membrane traffic. (PMID: 16782399) Seet L.F. … Hong W. (Biochim. Biophys. Acta 2006) 2 3
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study. (PMID: 17903292) Hwang S.J. … Fox C.S. (BMC Med. Genet. 2007) 48

Products for SNX31 Gene

Sources for SNX31 Gene

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