SNX30 Gene
protein-coding GIFtS : 44
GCID: GC09 P115513
sorting nexin family member 30
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Aliasesfor SNX30 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Sorting Nexin Family Member 30 1 2 ATG24A1 2 Sorting Nexin-302
Export aliases for SNX30 gene to outside databases Previous GC identifers: GC09P112594 GC09P114519 GC09P085110
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Summariesfor SNX30 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section UniProtKB/Swiss-Prot: SNX30_HUMAN, Q5VWJ9 Function : May be involved in several stages of intracellular trafficking (By similarity)
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Genomic Viewsfor SNX30 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000009.11 NC_018920.1 NT_008470.19 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the SNX30 gene promoter: Max1 FOXO3 Meis-1b YY1 MEF-2A FOXO3a aMEF-2 Meis-1a c-Myc Meis-1 Other transcription factors Search SABiosciences Chromatin IP Primers for SNX30 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat SNX30
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 9q32 Ensembl cytogenetic band: 9q32 HGNC cytogenetic band: 9q33.1 SNX30 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 9 GeneLoc Exon Structure
GeneLoc location for GC09P115513: view genomic region
(about GC identifiers )
Start:
115,513,118 bp from pter
End:
115,637,267 bp from pter
Size:
124,150 bases
Orientation:
plus strand
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Proteinsfor SNX30 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: SNX30_HUMAN, Q5VWJ9 (See
protein sequence )Recommended Name: Sorting nexin-30 Size : 437 amino acids; 49677 DaExplore the universe of human proteins at neXtProt for SNX30: NX_Q5VWJ9 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q5VWJ9 SNX30 Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins: NP_001013012.1 ENSEMBL proteins: ENSP00000363349 ENSP00000390454 Human Recombinant Protein Products: Gene Ontology (GO): 1 cellular component term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0005737 cytoplasm
IEA --
SNX30 for ontologies About GeneDecksing SNX30 Antibody Products: Assay Products for SNX30:
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Protein
Domains / Familiesfor SNX30 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
SNX30 for domains About GeneDecksing 2 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry Q5VWJ9 ProtoNet protein and cluster: Q5VWJ9
1 Blocks protein family : IPB001683 Phox-like UniProtKB/Swiss-Prot: SNX30_HUMAN, Q5VWJ9 Similarity : Belongs to the sorting nexin familySimilarity : Contains 1 PX (phox homology) domain
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Functionfor SNX30 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Function Summary: UniProtKB/Swiss-Prot: SNX30_HUMAN, Q5VWJ9 Function : May be involved in several stages of intracellular trafficking (By similarity)
Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for SNX30 (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for SNX30OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: SNX30 (NM_001012994 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SNX30 Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SNX30
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNX30
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0035091 phosphatidylinositol binding
IEA --
SNX30 for ontologies About GeneDecksing
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Pathways & Interactionsfor SNX30 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SNX30 STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)5/38 Interacting proteins for SNX30 (Q5VWJ9 3 ENSP00000363349 4 ) via UniProtKB, MINT, STRING , and/or I2D (see all 38 )About this table Gene Ontology (GO): 2 biological process terms (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0007154 cell communication
IEA -- GO:0015031 protein transport
IEA --
SNX30 for ontologies About GeneDecksing
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Drugs & Compoundsfor SNX30 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for SNX30 Search CenterWatch for drugs/clinical trials and news about SNX30
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Transcriptsfor SNX30 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for SNX30 gene: NM_001012994.1 Unigene Cluster for SNX30:
Sorting nexin family member 30 Hs.522350 [show with all ESTs ] Unigene Representative Sequence: NM_001012994 2 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000374232 (uc004bgj.4 uc004bgi.4 ) ENST00000416585 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for SNX30 (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for SNX30OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: SNX30 (NM_001012994 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SNX30 Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SNX30
Additional cDNA sequence: AK091599.1 AK092908.1 AK126644.1 AK127013.1 AK128710.1 AK129991.1 BC014914.1
7 DOTS entries : DT.92023637 DT.113583
DT.97798459 DT.95147323 DT.121209085 DT.92060011 DT.99960599 24/99 AceView cDNA sequences (see all 99 ):
AA398365 BF224225 AA401207 AL135553 AL135554 BU734161 AK091599 CK001821 AW025233 AK092908 BX644115 BX367137 BM749525 AI914181 AA765181 BQ278259 BG819393 BF934642 BQ232074 AK127013 BM989815 BX501372 AW292774 AA187888 GeneLoc Exon Structure
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Expression for SNX30 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section SNX30 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: --
About this image See SNX30 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for SNX30 SOURCE GeneReport for Unigene cluster: Hs.522350 SABiosciences Custom PCR Arrays for SNX30 Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for SNX30Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat SNX30 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat SNX30 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat SNX30 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNX30
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Orthologsfor SNX30 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of eukaryotes.
Orthologs for SNX30 gene from 7/26 species (see all 26 ) About this table
Organism
Taxonomic classification
Gene
Description
Human Similarity
Orthology Type
Details
chicken (Gallus gallus)
Aves
SNX301
sorting nexin family member 30
77.73(n) 87.79(a)
 
427330 XM_424910.2 XP_424910.2
lizard (Anolis carolinensis)
Reptilia
SNX306
--
85(a)
1 ↔ 1
2(57903972-57920156)
zebrafish (Danio rerio)
Actinopterygii
snx301
sorting nexin family member 30
70.61(n) 78.49(a)
 
550496 NM_001017798.1 NP_001017798.1
honey bee (Apis mellifera)
Insecta
--
--
32(a)
1 → many
Group8.19(1168-3316)
baker's yeast (Saccharomyces cerevisiae)
Saccharomycetes
SNX4(YJL036W)4 SNX41
Sorting nexin, involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Golgi network and in cytoplasm to vacuole transport; contains a PX phosphoinositide-binding domain; forms complexes with Snx41p and with Atg20p less 4 Snx4p1
44.01(n) 1 30.21(a) 1
 
10(378825-380096) 4 853416 1, 4 NP_012498.1 1, 4
thale cress (Arabidopsis thaliana)
eudicotyledons
SNX16
sorting nexin 1
22(a)
possible ortholog
5(1856008-1858785)
rice (Oryza sativa)
Liliopsida
--
sorting nexin 1, putative, expressed
22(a)
possible ortholog
1(37314248-37319474)
ENSEMBL Gene Tree for SNX30 (if available)TreeFam Gene Tree for SNX30 (if available)
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Paralogsfor SNX30 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for SNX30 gene SNX7 2 SNX4 2 4 SIMAP similar genes for SNX30 using alignment to 2 protein entries: SNX30_HUMAN (see all proteins ):SNX7 SNX3 SNX10 SNX12
SNX30 for paralogs About GeneDecksing
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Genomic Variantsfor SNX30 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 9 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for SNX30 (115513118 - 115637267 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 10 variations for SNX30 10 CNVs : 3779 96263 2831 83154 2832 37770 5414 8631 52675 33149
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing SNX30
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Disorders
/ Diseasesfor SNX30 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
SNX30 for disorders About GeneDecksing 2 diseases for SNX30 : About MalaCards cleft lip/palate cleft lip Human Genome Epidemiology (HuGE) Navigator: SNX30 (1 document)Export disorders for SNX30 gene to outside databases
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Publicationsfor SNX30 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for SNX30 gene, integrated from 9 sources (see all 11 ): (articles sorted by number of sources associating them with SNX30) Utopia : connect your pdf to the dynamic world of online information
Comprehensive analysis of interactions between the Src -associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome. (PubMed id 22745667) 1 Asbach B....Wagner R. (2012) Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983) 1 Kim W....Gygi S.P. (2011) Initial characterization of the human central proteome. (PubMed id 21269460) 2 Burkard T.R.... Colinge J. (2011) Follow-up association studies of chromosome region 9q and nonsyndromic cleft lip/palate. (PubMed id 20583170) 1 Letra A....Vieira A.R. (2010) Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231) 2 Olsen J.V....Mann M. (2010) A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648) 2 Dephoure N.... Gygi S.P. (2008) Identification of preferred protein interactions by phage-display of the human Src homology-3 proteome. (PubMed id 16374509) 1 Kaerkkaeinen S.... Saksela K. (2006) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 Ota T.... Sugano S. (2004) DNA sequence and analysis of human chromosome 9. (PubMed id 15164053) 2 Humphray S.J.... Dunham I. (2004) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 Strausberg R.L....Marra M.A. (2002)
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External Searches for SNX30 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing SNX30 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing SNX30 gene
(According to HUGE )
About This Section --
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Specialized Databases showing SNX30 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for SNX30 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for SNX30 gene: Search GeneIP for patents involving SNX30 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor SNX30 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
Browse OriGene Antibodies OriGene shRNA RFP for SNX30 OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for SNX30 OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for SNX30 OriGene Protein Over-expression Lysate for SNX30 Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for SNX30 OriGene 3'-UTR Clone for SNX30 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for SNX30 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for SNX30 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for SNX30 OriGene Custom Protein Services for SNX30 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SNX30 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing SNX30 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat SNX30 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat SNX30 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat SNX30 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat SNX30
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SNX30 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNX30
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Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SNX30
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Aliases for SNX30
Databases for SNX30
Disorders / Diseases for SNX30
Domains / Families for SNX30
Drugs / Compounds for SNX30
Expression for SNX30
Function for SNX30
Genomic Views for SNX30
Intellectual Property for SNX30
Orthologs for SNX30
Paralogs for SNX30
Pathways / Interactions for SNX30
Products for SNX30
Proteins for SNX30
Publications for SNX30
Search Box for SNX30
Summaries for SNX30
Transcripts for SNX30
Variants for SNX30
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