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Aliases for SNX30 Gene

Aliases for SNX30 Gene

  • Sorting Nexin Family Member 30 2 3
  • Sorting Nexin-30 3
  • ATG24A 3

External Ids for SNX30 Gene

Previous GeneCards Identifiers for SNX30 Gene

  • GC09P112594
  • GC09P114519
  • GC09P115513
  • GC09P085110

Summaries for SNX30 Gene

GeneCards Summary for SNX30 Gene

SNX30 (Sorting Nexin Family Member 30) is a Protein Coding gene. GO annotations related to this gene include phosphatidylinositol binding. An important paralog of this gene is SNX4.

UniProtKB/Swiss-Prot for SNX30 Gene

  • May be involved in several stages of intracellular trafficking.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNX30 Gene

Genomics for SNX30 Gene

Regulatory Elements for SNX30 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SNX30 Gene

112,749,638 bp from pter
112,881,671 bp from pter
132,034 bases
Plus strand

Genomic View for SNX30 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SNX30 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNX30 Gene

Proteins for SNX30 Gene

  • Protein details for SNX30 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Sorting nexin-30
    Protein Accession:
    Secondary Accessions:

    Protein attributes for SNX30 Gene

    437 amino acids
    Molecular mass:
    49677 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SNX30 Gene

Proteomics data for SNX30 Gene at MOPED

Post-translational modifications for SNX30 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SNX30 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for SNX30 Gene

Domains for SNX30 Gene

Gene Families for SNX30 Gene

  • SNX :Sorting nexins

Protein Domains for SNX30 Gene


Suggested Antigen Peptide Sequences for SNX30 Gene

Graphical View of Domain Structure for InterPro Entry



  • Q5VWJ9
  • Contains 1 PX (phox homology) domain.
  • Belongs to the sorting nexin family.
genes like me logo Genes that share domains with SNX30: view

Function for SNX30 Gene

Molecular function for SNX30 Gene

UniProtKB/Swiss-Prot Function:
May be involved in several stages of intracellular trafficking.

Gene Ontology (GO) - Molecular Function for SNX30 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 23085988
GO:0035091 phosphatidylinositol binding IBA --
genes like me logo Genes that share ontologies with SNX30: view

Animal Model Products

miRNA for SNX30 Gene

miRTarBase miRNAs that target SNX30

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SNX30

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for SNX30 Gene

Localization for SNX30 Gene

Subcellular locations from

Jensen Localization Image for SNX30 Gene COMPARTMENTS Subcellular localization image for SNX30 gene
Compartment Confidence
cytosol 3
nucleus 2

Gene Ontology (GO) - Cellular Components for SNX30 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm --
GO:0005768 endosome IBA --
GO:0019898 extrinsic component of membrane IBA --
genes like me logo Genes that share ontologies with SNX30: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for SNX30 Gene

Pathways for SNX30 Gene

SuperPathways for SNX30 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SNX30 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006886 intracellular protein transport --
GO:0006897 endocytosis IBA --
GO:0006915 apoptotic process --
GO:0015031 protein transport IEA --
GO:0016050 vesicle organization IBA --
genes like me logo Genes that share ontologies with SNX30: view

No data available for Pathways by source for SNX30 Gene

Transcripts for SNX30 Gene

Unigene Clusters for SNX30 Gene

Sorting nexin family member 30:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SNX30

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNX30 Gene

No ASD Table

Relevant External Links for SNX30 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SNX30 Gene

mRNA expression in normal human tissues for SNX30 Gene

Protein differential expression in normal tissues for SNX30 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (20.1), Saliva (6.9), Frontal cortex (6.7), and Fetal Brain (6.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for SNX30 Gene

SOURCE GeneReport for Unigene cluster for SNX30 Gene Hs.522350

genes like me logo Genes that share expressions with SNX30: view

Expression partners for SNX30 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SNX30 Gene

Orthologs for SNX30 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for SNX30 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SNX30 35
  • 91 (n)
  • 95.88 (a)
SNX30 36
  • 96 (a)
(Canis familiaris)
Mammalia SNX30 35
  • 92.03 (n)
  • 97.92 (a)
SNX30 36
  • 93 (a)
(Mus musculus)
Mammalia Snx30 35
  • 90.31 (n)
  • 95.42 (a)
Snx30 16
Snx30 36
  • 95 (a)
(Pan troglodytes)
Mammalia SNX30 35
  • 98.63 (n)
  • 98.63 (a)
SNX30 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Snx30 35
  • 90.62 (n)
  • 96.8 (a)
(Monodelphis domestica)
Mammalia SNX30 36
  • 87 (a)
(Ornithorhynchus anatinus)
Mammalia SNX30 36
  • 87 (a)
(Gallus gallus)
Aves SNX30 35
  • 77.73 (n)
  • 87.79 (a)
SNX30 36
  • 87 (a)
(Anolis carolinensis)
Reptilia SNX30 36
  • 85 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia snx30 35
  • 73.78 (n)
  • 81.65 (a)
(Danio rerio)
Actinopterygii snx30 35
  • 70.76 (n)
  • 78.96 (a)
snx30 36
  • 78 (a)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_ACR074W 35
  • 46.63 (n)
  • 31.12 (a)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0C10967g 35
  • 42.89 (n)
  • 28.96 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SNX4 35
  • 43.91 (n)
  • 30.21 (a)
SNX4 36
  • 22 (a)
SNX4 38
bread mold
(Neurospora crassa)
Ascomycetes NCU03218 35
  • 43.13 (n)
  • 29.08 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPAC6F6.12 35
  • 42.94 (n)
  • 28.82 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.9288 36
  • 37 (a)
Species with no ortholog for SNX30:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNX30 Gene

Gene Tree for SNX30 (if available)
Gene Tree for SNX30 (if available)

Paralogs for SNX30 Gene

Paralogs for SNX30 Gene

Selected SIMAP similar genes for SNX30 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with SNX30: view

Variants for SNX30 Gene

Sequence variations from dbSNP and Humsavar for SNX30 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs15076 -- 112,874,778(-) GTCAA(A/C)AAAAA utr-variant-3-prime
rs700122 -- 112,789,567(+) AGTAT(A/G)TGCTT intron-variant
rs715667 -- 112,768,284(-) ACATC(A/G)AGAGG intron-variant
rs734694 -- 112,849,061(-) AAAAA(A/C)CACAT intron-variant
rs749054 -- 112,848,596(+) ATGCG(C/T)GTTCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SNX30 Gene

Variant ID Type Subtype PubMed ID
dgv2411e1 CNV Complex 17122850
dgv2412e1 CNV Complex 17122850
nsv515899 CNV Gain+Loss 19592680
dgv262e55 CNV Gain 17911159
dgv2413e1 CNV Complex 17122850
nsv471317 CNV Gain 18288195
nsv515121 CNV Gain 21397061
nsv442163 CNV CNV 18776908
nsv893733 CNV Gain 21882294
nsv8559 CNV Gain 18304495
esv2422302 CNV Deletion 17116639
essv15169 CNV CNV 17122850
nsv8560 CNV Loss 18304495
nsv825049 CNV Gain 20364138
esv995366 CNV Loss 20482838
esv1549334 CNV Insertion 17803354

Relevant External Links for SNX30 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SNX30 Gene

Disorders for SNX30 Gene

Relevant External Links for SNX30

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for SNX30 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for SNX30 Gene

Publications for SNX30 Gene

  1. Follow-up association studies of chromosome region 9q and nonsyndromic cleft lip/palate. (PMID: 20583170) Letra A. … Vieira A.R. (Am. J. Med. Genet. A 2010) 3 48
  2. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3
  3. Comprehensive analysis of interactions between the Src-associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome. (PMID: 22745667) Asbach B. … Wagner R. (PLoS ONE 2012) 3
  4. Molecular basis for SNX-BAR-mediated assembly of distinct endosomal sorting tubules. (PMID: 23085988) van Weering J.R. … Cullen P.J. (EMBO J. 2012) 3
  5. Genome-wide association analysis demonstrates the highly polygenic character of age-related hearing impairment. (PMID: 24939585) Fransen E. … Friedman R.A. (Eur. J. Hum. Genet. 2015) 3

Products for SNX30 Gene

Sources for SNX30 Gene

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