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Aliases for SNX29 Gene

Aliases for SNX29 Gene

  • Sorting Nexin 29 2 3
  • RUN Domain-Containing Protein 2A 3 4
  • RUN Domain Containing 2A 2 3
  • RUNDC2A 3 4
  • Sorting Nexin-29 3
  • A-388D4.1 3

External Ids for SNX29 Gene

Previous HGNC Symbols for SNX29 Gene

  • RUNDC2A

Previous GeneCards Identifiers for SNX29 Gene

  • GC16P012053
  • GC16P012146

Summaries for SNX29 Gene

GeneCards Summary for SNX29 Gene

SNX29 (Sorting Nexin 29) is a Protein Coding gene. GO annotations related to this gene include phosphatidylinositol binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNX29 Gene

Genomics for SNX29 Gene

Regulatory Elements for SNX29 Gene

Genomic Location for SNX29 Gene

Start:
11,976,737 bp from pter
End:
12,574,289 bp from pter
Size:
597,553 bases
Orientation:
Plus strand

Genomic View for SNX29 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SNX29 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNX29 Gene

Proteins for SNX29 Gene

  • Protein details for SNX29 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TEQ0-SNX29_HUMAN
    Recommended name:
    Sorting nexin-29
    Protein Accession:
    Q8TEQ0
    Secondary Accessions:
    • B5MDW2
    • Q8N2X2
    • Q9HA26

    Protein attributes for SNX29 Gene

    Size:
    813 amino acids
    Molecular mass:
    91254 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB14033.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact.; Evidence={ECO:0000305};

    Alternative splice isoforms for SNX29 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SNX29 Gene

Proteomics data for SNX29 Gene at MOPED

Post-translational modifications for SNX29 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SNX29 Gene

No data available for DME Specific Peptides for SNX29 Gene

Domains for SNX29 Gene

Gene Families for SNX29 Gene

HGNC:
  • SNX :Sorting nexins

Protein Domains for SNX29 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for SNX29 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8TEQ0

UniProtKB/Swiss-Prot:

SNX29_HUMAN :
  • Q8TEQ0
Domain:
  • Contains 1 PX (phox homology) domain.
  • Contains 1 RUN domain.
Family:
  • Belongs to the sorting nexin family.
genes like me logo Genes that share domains with SNX29: view

Function for SNX29 Gene

Gene Ontology (GO) - Molecular Function for SNX29 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003777 microtubule motor activity --
GO:0035091 phosphatidylinositol binding IEA --
genes like me logo Genes that share ontologies with SNX29: view

Phenotypes for SNX29 Gene

GenomeRNAi human phenotypes for SNX29:
genes like me logo Genes that share phenotypes with SNX29: view

Animal Model Products

miRNA for SNX29 Gene

miRTarBase miRNAs that target SNX29

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SNX29

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for SNX29 Gene

Localization for SNX29 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SNX29 Gene COMPARTMENTS Subcellular localization image for SNX29 gene
Compartment Confidence
cytosol 2

Gene Ontology (GO) - Cellular Components for SNX29 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005871 kinesin complex --
GO:0070062 extracellular exosome IDA 23376485
genes like me logo Genes that share ontologies with SNX29: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for SNX29 Gene

Pathways for SNX29 Gene

SuperPathways for SNX29 Gene

No Data Available

Interacting Proteins for SNX29 Gene

Selected Interacting proteins: Q8TEQ0-SNX29_HUMAN for SNX29 Gene via I2D

Symbol External ID(s) Details
NF2

Gene Ontology (GO) - Biological Process for SNX29 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007018 microtubule-based movement --
GO:0008152 metabolic process --
genes like me logo Genes that share ontologies with SNX29: view

No data available for Pathways by source for SNX29 Gene

Transcripts for SNX29 Gene

Unigene Clusters for SNX29 Gene

Sorting nexin 29:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SNX29

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNX29 Gene

No ASD Table

Relevant External Links for SNX29 Gene

GeneLoc Exon Structure for
SNX29
ECgene alternative splicing isoforms for
SNX29

Expression for SNX29 Gene

mRNA expression in normal human tissues for SNX29 Gene

Protein differential expression in normal tissues for SNX29 Gene

This gene is overexpressed in Fetal heart (31.4), Monocytes (13.9), and Peripheral blood mononuclear cells (10.3).

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for SNX29 Gene

SOURCE GeneReport for Unigene cluster for SNX29 Gene Hs.458401

genes like me logo Genes that share expressions with SNX29: view

Expression partners for SNX29 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SNX29 Gene

Orthologs for SNX29 Gene

This gene was present in the common ancestor of animals.

Orthologs for SNX29 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia SNX29 35
  • 89.3 (n)
  • 91.51 (a)
SNX29 36
  • 90 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SNX29 35
  • 89.59 (n)
  • 93.11 (a)
SNX29 36
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Snx29 35
  • 85.16 (n)
  • 87.55 (a)
Snx29 36
  • 81 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia SNX29 35
  • 97.29 (n)
  • 96.92 (a)
SNX29 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Snx29 35
  • 84.83 (n)
  • 87.05 (a)
oppossum
(Monodelphis domestica)
Mammalia SNX29 36
  • 80 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SNX29 36
  • 76 (a)
OneToOne
chicken
(Gallus gallus)
Aves SNX29 35
  • 72.75 (n)
  • 79.25 (a)
SNX29 36
  • 76 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SNX29 36
  • 57 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia snx29 35
  • 67.7 (n)
  • 72.28 (a)
zebrafish
(Danio rerio)
Actinopterygii Dr.9983 35
snx29 35
  • 65.1 (n)
  • 64.97 (a)
snx29 36
  • 58 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG5439 36
  • 13 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 29 (a)
OneToOne
Species with no ortholog for SNX29:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNX29 Gene

ENSEMBL:
Gene Tree for SNX29 (if available)
TreeFam:
Gene Tree for SNX29 (if available)

Paralogs for SNX29 Gene

Selected SIMAP similar genes for SNX29 Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with SNX29: view

No data available for Paralogs for SNX29 Gene

Variants for SNX29 Gene

Sequence variations from dbSNP and Humsavar for SNX29 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs31677 -- 12,346,380(-) ttaaa(C/T)aataa intron-variant
rs31678 -- 12,346,347(-) ggtta(C/T)gtaaa intron-variant
rs31679 -- 12,345,607(-) TAGTG(A/G)CAACA intron-variant
rs31712 -- 12,449,038(+) TACTA(C/G/T)GCAAC intron-variant
rs31713 -- 12,449,370(+) AGGCA(C/T)GGCAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SNX29 Gene

Variant ID Type Subtype PubMed ID
nsv905347 CNV Gain 21882294
nsv527197 CNV Loss 19592680
esv2669944 CNV Deletion 23128226
esv2666642 CNV Deletion 23128226
esv2713986 CNV Deletion 23290073
nsv528952 CNV Loss 19592680
esv273120 CNV Insertion 20981092
esv1207869 CNV Insertion 17803354
nsv905348 CNV Loss 21882294
nsv833141 CNV Gain 17160897
esv2658919 CNV Deletion 23128226
esv2664429 CNV Deletion 23128226
nsv516932 CNV Gain 19592680
nsv905349 CNV Loss 21882294
dgv481e199 CNV Deletion 23128226
esv2713987 CNV Deletion 23290073
nsv827555 CNV Loss 20364138
esv2713988 CNV Deletion 23290073
esv1672031 CNV Insertion 17803354
nsv1736 CNV Loss 18451855
nsv520000 CNV Loss 19592680
esv2713989 CNV Deletion 23290073
esv1735749 CNV Insertion 17803354
nsv524986 CNV Loss 19592680
esv2751546 CNV Loss 17911159
nsv507803 CNV Insertion 20534489
esv29309 CNV Loss 19812545
nsv9348 CNV Loss 18304495
dgv806e1 CNV Complex 17122850
nsv528018 CNV Loss 19592680
nsv9349 CNV Loss 18304495
esv1005656 CNV Loss 20482838
esv23890 CNV Loss 19812545
nsv437802 CNV Loss 16327808
nsv517039 CNV Loss 19592680

Relevant External Links for SNX29 Gene

HapMap Linkage Disequilibrium report
SNX29

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SNX29 Gene

Disorders for SNX29 Gene

Relevant External Links for SNX29

Genetic Association Database (GAD)
SNX29
Human Genome Epidemiology (HuGE) Navigator
SNX29

No disorders were found for SNX29 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for SNX29 Gene

Publications for SNX29 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 3 4
  3. The Phox (PX) domain proteins and membrane traffic. (PMID: 16782399) Seet L.F. … Hong W. (Biochim. Biophys. Acta 2006) 2 3
  4. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PMID: 19773279) Hosgood H.D. … Lan Q. (Occup Environ Med 2009) 3
  5. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PMID: 22589738) Fox C.S. … Borecki I.B. (PLoS Genet. 2012) 3

Products for SNX29 Gene

Sources for SNX29 Gene

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