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Aliases for SNX29 Gene

Aliases for SNX29 Gene

  • Sorting Nexin 29 2 3 5
  • RUN Domain-Containing Protein 2A 3 4
  • RUN Domain Containing 2A 2 3
  • RUNDC2A 3 4
  • A-388D4.1 3

External Ids for SNX29 Gene

Previous HGNC Symbols for SNX29 Gene


Previous GeneCards Identifiers for SNX29 Gene

  • GC16P012053
  • GC16P012146

Summaries for SNX29 Gene

GeneCards Summary for SNX29 Gene

SNX29 (Sorting Nexin 29) is a Protein Coding gene. GO annotations related to this gene include microtubule motor activity and phosphatidylinositol binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNX29 Gene

Genomics for SNX29 Gene

Regulatory Elements for SNX29 Gene

Enhancers for SNX29 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around SNX29 on UCSC Golden Path with GeneCards custom track

Promoters for SNX29 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around SNX29 on UCSC Golden Path with GeneCards custom track

Genomic Location for SNX29 Gene

11,976,734 bp from pter
12,574,289 bp from pter
597,556 bases
Plus strand

Genomic View for SNX29 Gene

Genes around SNX29 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNX29 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNX29 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNX29 Gene

Proteins for SNX29 Gene

  • Protein details for SNX29 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Sorting nexin-29
    Protein Accession:
    Secondary Accessions:
    • B5MDW2
    • Q8N2X2
    • Q9HA26

    Protein attributes for SNX29 Gene

    813 amino acids
    Molecular mass:
    91254 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB14033.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact.; Evidence={ECO:0000305};

    Alternative splice isoforms for SNX29 Gene


neXtProt entry for SNX29 Gene

Proteomics data for SNX29 Gene at MOPED

Post-translational modifications for SNX29 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SNX29 Gene

No data available for DME Specific Peptides for SNX29 Gene

Domains & Families for SNX29 Gene

Gene Families for SNX29 Gene

Protein Domains for SNX29 Gene


Suggested Antigen Peptide Sequences for SNX29 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 PX (phox homology) domain.
  • Belongs to the sorting nexin family.
  • Contains 1 PX (phox homology) domain.
  • Contains 1 RUN domain.
  • Belongs to the sorting nexin family.
genes like me logo Genes that share domains with SNX29: view

Function for SNX29 Gene

genes like me logo Genes that share phenotypes with SNX29: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SNX29 Gene

Localization for SNX29 Gene

Subcellular locations from

Jensen Localization Image for SNX29 Gene COMPARTMENTS Subcellular localization image for SNX29 gene
Compartment Confidence
extracellular 5
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for SNX29 Gene

Pathways & Interactions for SNX29 Gene

SuperPathways for SNX29 Gene

No Data Available

Interacting Proteins for SNX29 Gene

Selected Interacting proteins: Q8TEQ0-SNX29_HUMAN for SNX29 Gene via I2D

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for SNX29 Gene


No data available for Pathways by source and SIGNOR curated interactions for SNX29 Gene

Drugs & Compounds for SNX29 Gene

No Compound Related Data Available

Transcripts for SNX29 Gene

Unigene Clusters for SNX29 Gene

Sorting nexin 29:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SNX29 Gene

No ASD Table

Relevant External Links for SNX29 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SNX29 Gene

mRNA expression in normal human tissues for SNX29 Gene

Protein differential expression in normal tissues from HIPED for SNX29 Gene

This gene is overexpressed in Fetal heart (31.4), Monocytes (13.9), and Peripheral blood mononuclear cells (10.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for SNX29 Gene

SOURCE GeneReport for Unigene cluster for SNX29 Gene Hs.458401

genes like me logo Genes that share expression patterns with SNX29: view

Protein tissue co-expression partners for SNX29 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SNX29 Gene

Orthologs for SNX29 Gene

This gene was present in the common ancestor of animals.

Orthologs for SNX29 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SNX29 35
  • 89.3 (n)
  • 91.51 (a)
SNX29 36
  • 90 (a)
(Canis familiaris)
Mammalia SNX29 35
  • 89.59 (n)
  • 93.11 (a)
SNX29 36
  • 89 (a)
(Mus musculus)
Mammalia Snx29 35
  • 85.16 (n)
  • 87.55 (a)
Snx29 16
Snx29 36
  • 81 (a)
(Pan troglodytes)
Mammalia SNX29 35
  • 97.29 (n)
  • 96.92 (a)
SNX29 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Snx29 35
  • 84.83 (n)
  • 87.05 (a)
(Monodelphis domestica)
Mammalia SNX29 36
  • 80 (a)
(Ornithorhynchus anatinus)
Mammalia SNX29 36
  • 76 (a)
(Gallus gallus)
Aves SNX29 35
  • 72.75 (n)
  • 79.25 (a)
SNX29 36
  • 76 (a)
(Anolis carolinensis)
Reptilia SNX29 36
  • 57 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia snx29 35
  • 67.7 (n)
  • 72.28 (a)
(Danio rerio)
Actinopterygii Dr.9983 35
snx29 35
  • 65.1 (n)
  • 64.97 (a)
snx29 36
  • 58 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG5439 36
  • 13 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 29 (a)
Species with no ortholog for SNX29:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNX29 Gene

Gene Tree for SNX29 (if available)
Gene Tree for SNX29 (if available)

Paralogs for SNX29 Gene

(2) SIMAP similar genes for SNX29 Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with SNX29: view

No data available for Paralogs for SNX29 Gene

Variants for SNX29 Gene

Sequence variations from dbSNP and Humsavar for SNX29 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs3862447 -- 11,995,384(-) AATGA(G/T)CTTAA intron-variant
rs3862448 -- 12,037,630(+) TTCCC(A/G)TAGGA intron-variant
rs3862449 -- 12,037,639(+) GAAAG(A/C/T)GGGGT intron-variant
rs3862454 -- 12,037,799(+) aaaaa(A/T)aaaaa intron-variant
rs3862455 -- 12,037,811(+) ttagc(C/T)gtgta intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SNX29 Gene

Variant ID Type Subtype PubMed ID
nsv905347 CNV Gain 21882294
nsv527197 CNV Loss 19592680
esv2669944 CNV Deletion 23128226
esv2666642 CNV Deletion 23128226
esv2713986 CNV Deletion 23290073
nsv528952 CNV Loss 19592680
esv273120 CNV Insertion 20981092
esv1207869 CNV Insertion 17803354
nsv905348 CNV Loss 21882294
nsv833141 CNV Gain 17160897
esv2658919 CNV Deletion 23128226
esv2664429 CNV Deletion 23128226
nsv516932 CNV Gain 19592680
nsv905349 CNV Loss 21882294
dgv481e199 CNV Deletion 23128226
esv2713987 CNV Deletion 23290073
nsv827555 CNV Loss 20364138
esv2713988 CNV Deletion 23290073
esv1672031 CNV Insertion 17803354
nsv1736 CNV Loss 18451855
nsv520000 CNV Loss 19592680
esv2713989 CNV Deletion 23290073
esv1735749 CNV Insertion 17803354
nsv524986 CNV Loss 19592680
esv2751546 CNV Loss 17911159
nsv507803 CNV Insertion 20534489
esv29309 CNV Loss 19812545
nsv9348 CNV Loss 18304495
dgv806e1 CNV Complex 17122850
nsv528018 CNV Loss 19592680
nsv9349 CNV Loss 18304495
esv1005656 CNV Loss 20482838
esv23890 CNV Loss 19812545
nsv437802 CNV Loss 16327808
nsv517039 CNV Loss 19592680

Variation tolerance for SNX29 Gene

Residual Variation Intolerance Score: 22.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.12; 51.21% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for SNX29 Gene

Disorders for SNX29 Gene

Relevant External Links for SNX29

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SNX29 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNX29 Gene

Publications for SNX29 Gene

  1. The Phox (PX) domain proteins and membrane traffic. (PMID: 16782399) Seet L.F. … Hong W. (Biochim. Biophys. Acta 2006) 2 3 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  4. Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality. (PMID: 24159190) SeppAolAo I. … LehtimAoki T. (Eur. Heart J. 2014) 3
  5. Genome-wide shRNA screening identifies host factors involved in early endocytic events for HIV-1-induced CD4 down-regulation. (PMID: 25496667) Landi A. … Verhasselt B. (Retrovirology 2014) 3

Products for SNX29 Gene

Sources for SNX29 Gene