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Aliases for SNX24 Gene

Aliases for SNX24 Gene

  • Sorting Nexin 24 2 3
  • Sorting Nexing 24 3
  • Sorting Nexin-24 3
  • PRO1284 3
  • SBBI31 3

External Ids for SNX24 Gene

Previous GeneCards Identifiers for SNX24 Gene

  • GC05P122508
  • GC05P122212
  • GC05P122257
  • GC05P122209
  • GC05P117368

Summaries for SNX24 Gene

GeneCards Summary for SNX24 Gene

SNX24 (Sorting Nexin 24) is a Protein Coding gene. GO annotations related to this gene include phosphatidylinositol binding. An important paralog of this gene is SNX22.

UniProtKB/Swiss-Prot for SNX24 Gene

  • May be involved in several stages of intracellular trafficking.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNX24 Gene

Genomics for SNX24 Gene

Regulatory Elements for SNX24 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SNX24 Gene

Start:
122,843,439 bp from pter
End:
123,029,354 bp from pter
Size:
185,916 bases
Orientation:
Plus strand

Genomic View for SNX24 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SNX24 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNX24 Gene

Proteins for SNX24 Gene

  • Protein details for SNX24 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y343-SNX24_HUMAN
    Recommended name:
    Sorting nexin-24
    Protein Accession:
    Q9Y343
    Secondary Accessions:
    • Q6UY33

    Protein attributes for SNX24 Gene

    Size:
    169 amino acids
    Molecular mass:
    19818 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for SNX24 Gene

    Alternative splice isoforms for SNX24 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SNX24 Gene

Proteomics data for SNX24 Gene at MOPED

Post-translational modifications for SNX24 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SNX24 Gene

No data available for DME Specific Peptides for SNX24 Gene

Domains for SNX24 Gene

Gene Families for SNX24 Gene

HGNC:
  • SNX :Sorting nexins

Protein Domains for SNX24 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for SNX24 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9Y343

UniProtKB/Swiss-Prot:

SNX24_HUMAN :
  • Q9Y343
Domain:
  • The PX domain mediates specific binding to membranes enriched in phosphatidylinositol 3-phosphate (PtdIns(P3)).
  • Contains 1 PX (phox homology) domain.
Family:
  • Belongs to the sorting nexin family.
genes like me logo Genes that share domains with SNX24: view

Function for SNX24 Gene

Molecular function for SNX24 Gene

UniProtKB/Swiss-Prot Function: May be involved in several stages of intracellular trafficking.

Gene Ontology (GO) - Molecular Function for SNX24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035091 phosphatidylinositol binding IEA --
genes like me logo Genes that share ontologies with SNX24: view

Animal Model Products

CRISPR Products

miRNA for SNX24 Gene

miRTarBase miRNAs that target SNX24

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for SNX24 Gene

Localization for SNX24 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SNX24 Gene

Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SNX24 Gene COMPARTMENTS Subcellular localization image for SNX24 gene
Compartment Confidence
cytosol 3
nucleus 2

Gene Ontology (GO) - Cellular Components for SNX24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane --
GO:0030659 cytoplasmic vesicle membrane IEA --
GO:0031410 cytoplasmic vesicle --
genes like me logo Genes that share ontologies with SNX24: view

Pathways for SNX24 Gene

SuperPathways for SNX24 Gene

No Data Available

Interacting Proteins for SNX24 Gene

Gene Ontology (GO) - Biological Process for SNX24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015031 protein transport IEA --
genes like me logo Genes that share ontologies with SNX24: view

No data available for Pathways by source for SNX24 Gene

Transcripts for SNX24 Gene

Unigene Clusters for SNX24 Gene

Sorting nexin 24:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SNX24

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNX24 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9
SP1: - -
SP2: -
SP3: - - -
SP4:

Relevant External Links for SNX24 Gene

GeneLoc Exon Structure for
SNX24
ECgene alternative splicing isoforms for
SNX24

Expression for SNX24 Gene

mRNA expression in normal human tissues for SNX24 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SNX24 Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (4.5).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for SNX24 Gene

SOURCE GeneReport for Unigene cluster for SNX24 Gene Hs.483200

genes like me logo Genes that share expressions with SNX24: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for SNX24 Gene

Orthologs for SNX24 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNX24 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNX24 35
  • 99.61 (n)
  • 100 (a)
SNX24 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SNX24 35
  • 94.08 (n)
  • 98.82 (a)
SNX24 36
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SNX24 35
  • 94.7 (n)
  • 98.01 (a)
SNX24 36
  • 76 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Snx24 35
  • 89.74 (n)
  • 97.04 (a)
Snx24 16
Snx24 36
  • 97 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SNX24 36
  • 94 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SNX24 36
  • 86 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Snx24 35
  • 88.36 (n)
  • 97.04 (a)
chicken
(Gallus gallus)
Aves SNX24 35
  • 84.81 (n)
  • 92.9 (a)
SNX24 36
  • 92 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SNX24 36
  • 75 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia snx24 35
  • 80.04 (n)
  • 88.62 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.6285 35
zebrafish
(Danio rerio)
Actinopterygii snx24 35
  • 73.02 (n)
  • 77.98 (a)
snx24 36
  • 76 (a)
OneToOne
Species with no ortholog for SNX24:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNX24 Gene

ENSEMBL:
Gene Tree for SNX24 (if available)
TreeFam:
Gene Tree for SNX24 (if available)

Paralogs for SNX24 Gene

Paralogs for SNX24 Gene

Selected SIMAP similar genes for SNX24 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with SNX24: view

Variants for SNX24 Gene

Sequence variations from dbSNP and Humsavar for SNX24 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs26369 -- 122,901,128(+) cctga(A/G)aggtg intron-variant
rs26370 -- 122,899,497(+) TCGAA(C/T)TCGCA intron-variant
rs26371 -- 122,870,830(+) AGGCT(A/G)TTGAT intron-variant
rs26372 -- 122,870,752(+) GAGAC(A/G)TGGAA intron-variant
rs27617 -- 122,900,839(+) GCCAA(A/T)AATTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SNX24 Gene

Variant ID Type Subtype PubMed ID
nsv830471 CNV Gain 17160897
esv2730708 CNV Deletion 23290073
esv2569438 CNV Deletion 19546169
esv2095337 CNV Deletion 18987734
esv4604 CNV Deletion 18987735
dgv213n6 CNV Loss 16902084
esv1008444 CNV Deletion 20482838
esv2730709 CNV Deletion 23290073
esv1686062 CNV Deletion 17803354
esv5852 CNV Loss 19470904

Relevant External Links for SNX24 Gene

HapMap Linkage Disequilibrium report
SNX24

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SNX24 Gene

Disorders for SNX24 Gene

Relevant External Links for SNX24

Genetic Association Database (GAD)
SNX24
genes like me logo Genes that share disorders with SNX24: view

No data available for UniProtKB/Swiss-Prot for SNX24 Gene

Publications for SNX24 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Sorting out the cellular functions of sorting nexins. (PMID: 12461558) Worby C.A. … Dixon J.E. (Nat. Rev. Mol. Cell Biol. 2002) 2 3
  3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3 4
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for SNX24 Gene

Sources for SNX24 Gene

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