Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



SNX22 Gene

protein-coding   GIFtS: 43
GCID: GC15P064443

Sorting Nexin 22

  Search for SNX22
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

This gene clusters with an RNA gene
Subcategory (RNA class): antisense

Quality score for the ORGUL clustered with this gene is 3

Aliases
Sorting Nexin 221 2
Sorting Nexin-222

External Ids:    HGNC: 163151   Entrez Gene: 798562   Ensembl: ENSG000001577347   UniProtKB: Q96L943   
ORGUL members:         

Export aliases for SNX22 gene to outside databases

Previous GC identifers: GC15P057603 GC15P062022 GC15P062159 GC15P062230 GC15P041268


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for SNX22 Gene:
The protein encoded by this gene is a sorting nexin that is found in the cytoplasm, where it interacts with
membrane-bound phosphatidylinositol 3-phosphate. The encoded protein may play a role in intracellular
trafficking. Two transcript variants, one protein-coding and the other not protein-coding, have been found for
this gene. (provided by RefSeq, Dec 2012)

GeneCards Summary for SNX22 Gene:
SNX22 (sorting nexin 22) is a protein-coding gene. GO annotations related to this gene include phosphatidylinositol binding. An important paralog of this gene is SNX24.

UniProtKB/Swiss-Prot: SNX22_HUMAN, Q96L94
Function: May be involved in several stages of intracellular trafficking (By similarity). Interacts with membranes
containing phosphatidylinositol 3-phosphate (PtdIns(3P))




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
Regulatory elements:
   Regulatory transcription factor binding sites in the SNX22 gene promoter:
         USF1   SREBP-1c   C/EBPalpha   E47   SREBP-1b   GATA-2   Arnt   SREBP-1a   USF-1   Hand1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSNX22 promoter sequence
   Search Chromatin IP Primers for SNX22

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SNX22


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q22.31   Ensembl cytogenetic band:  15q22.31   HGNC cytogenetic band: 15q22.1

SNX22 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SNX22 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P064443:  view genomic region     (about GC identifiers)

Start:
64,443,914 bp from pter      End:
64,449,680 bp from pter
Size:
5,767 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: SNX22_HUMAN, Q96L94 (See protein sequence)
Recommended Name: Sorting nexin-22  
Size: 193 amino acids; 22068 Da
1 PDB 3D structure from and Proteopedia for SNX22:
2ETT (3D)    
Secondary accessions: Q9H844

Explore the universe of human proteins at neXtProt for SNX22: NX_Q96L94

Explore proteomics data for SNX22 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SNX22 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_079074.2  
    ENSEMBL proteins: 
     ENSP00000323435   ENSP00000452692  

    SNX22 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for SNX22
    GenScript Custom Purified and Recombinant Proteins Services for SNX22
    Novus Biologicals SNX22 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SNX22

    SNX22 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for SNX22
    Novus Biologicals SNX22 Antibody
    Abcam antibodies for SNX22
    Cloud-Clone Corp. Antibodies for SNX22
    Search ThermoFisher Antibodies for SNX22
    LSBio Antibodies in human, mouse, rat for SNX22

    SNX22 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for SNX22
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SNX22
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SNX22
    Cloud-Clone Corp. CLIAs for SNX22


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    SNX: Sorting nexins

    1 InterPro protein domain:
     IPR001683 Phox

    Graphical View of Domain Structure for InterPro Entry Q96L94

    ProtoNet protein and cluster: Q96L94

    1 Blocks protein domain: IPB001683 Phox-like

    UniProtKB/Swiss-Prot: SNX22_HUMAN, Q96L94
    Domain: The PX domain mediates specific binding to membranes enriched in phosphatidylinositol 3-phosphate
    (PtdIns(P3))
    Similarity: Belongs to the sorting nexin family
    Similarity: Contains 1 PX (phox homology) domain


    SNX22 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SNX22_HUMAN, Q96L94
    Function: May be involved in several stages of intracellular trafficking (By similarity). Interacts with membranes
    containing phosphatidylinositol 3-phosphate (PtdIns(3P))

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0035091phosphatidylinositol binding IEA--
         
    SNX22 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SNX22
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SNX22

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SNX22
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SNX22

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat SNX22 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SNX22 (see all 15):
    hsa-miR-4265 hsa-miR-4303 hsa-miR-495 hsa-miR-516b hsa-miR-7-2* hsa-miR-130a* hsa-miR-200a hsa-miR-23c
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SNX22
    Predesigned siRNA for gene silencing in human, mouse, rat SNX22

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SNX22

    Clone
    Products:
         
    OriGene clones in human, mouse for SNX22 (see all 7)
    OriGene ORF clones in mouse, rat for SNX22
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SNX22 (NM_024798)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SNX22
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNX22

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SNX22
    Browse ESI BIO Cell Lines and PureStem Progenitors for SNX22 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNX22


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    SNX22_HUMAN, Q96L94: Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus2
    extracellular1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030659cytoplasmic vesicle membrane IEA--

    SNX22 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SNX22
    Interactions:

        Search GeneGlobe Interaction Network for SNX22

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5 Interacting proteins for SNX22 (Q96L942, 3 ENSP000003234354) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DVL3Q929973, ENSP000003160544I2D: score=3 STRING: ENSP00000316054
    POT1Q9NUX53, ENSP000003502494I2D: score=1 STRING: ENSP00000350249
    TERF2Q155543, ENSP000002549424I2D: score=1 STRING: ENSP00000254942
    B3GALT2ENSP000003564044STRING: ENSP00000356404
    --P310162MINT-8107489
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007154cell communication ----
    GO:0015031protein transport IEA--

    SNX22 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SNX22



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for SNX22 gene: 
    NM_024798.2  

    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000557789(uc002amz.1) ENST00000325881(uc002anc.1) ENST00000561334(uc002ana.1)
    ENST00000558466(uc002anb.1) ENST00000560607 ENST00000560945 ENST00000560997

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SNX22 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SNX22 (see all 15):
    hsa-miR-4265 hsa-miR-4303 hsa-miR-495 hsa-miR-516b hsa-miR-7-2* hsa-miR-130a* hsa-miR-200a hsa-miR-23c
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SNX22
    Predesigned siRNA for gene silencing in human, mouse, rat SNX22
    Clone
    Products:
         
    OriGene clones in human, mouse for SNX22 (see all 7)
    OriGene ORF clones in mouse, rat for SNX22
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SNX22 (NM_024798)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SNX22
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNX22
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for SNX22
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SNX22
      QuantiTect SYBR Green Assays in human, mouse, rat SNX22
      QuantiFast Probe-based Assays in human, mouse, rat SNX22

    Selected AceView cDNA sequences (see all 77):

    AI671317 BU071191 BE045919 BC030225 AY044653 AW025702 AI968104 R11214 
    BX104306 AI968213 D81932 AI939497 BC014660 BE671765 BQ066597 AU142897 
    AI632509 AI242191 AI339451 AI918684 BC019655 NM_024798 BF932623 AI470745 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for SNX22    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6
    SP1:                                          
    SP2:              -                           
    SP3:                                          
    SP4:                                          
    SP5:                                          


    ECgene alternative splicing isoforms for SNX22

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    SNX22 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SNX22 Expression
    About this image


    SNX22 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             Mature B-Cells Peripheral Blood
     
     Colon (Gastrointestinal Tract)
    SNX22 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SNX22 Protein Expression
        Custom PCR Arrays for SNX22
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for SNX22
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SNX22
    QuantiTect SYBR Green Assays in human, mouse, rat SNX22
    QuantiFast Probe-based Assays in human, mouse, rat SNX22
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNX22

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for SNX22 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Snx221 , 5 sorting nexin 221, 5 85.82(n)1
    84.57(a)1
      9 (35.69 cM)5
    3820831  NM_001025612.21  NP_001020783.11 
     660651765 
    chicken
    (Gallus gallus)
    Aves SNX221 sorting nexin 22 70.02(n)
    57.86(a)
      769119  XM_001231640.2  XP_001231641.1 
    lizard
    (Anolis carolinensis)
    Reptilia SNX226
    sorting nexin 22
    51(a)
    1 ↔ 1
    GL343490.1(368700-373263)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia snx221 sorting nexin 22 59.24(n)
    55.42(a)
      549386  NM_001016632.2  NP_001016632.1 
    zebrafish
    (Danio rerio)
    Actinopterygii snx221 sorting nexin 22 51.79(n)
    48.39(a)
      561624  NM_001045374.2  NP_001038839.2 


    ENSEMBL Gene Tree for SNX22 (if available)
    TreeFam Gene Tree for SNX22 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for SNX22 gene
    SNX242  
    1 SIMAP similar gene for SNX22 using alignment to 3 protein entries:     SNX22_HUMAN (see all proteins):
    SNX24

    SNX22 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for SNX22 (see all 138)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1399621971,2
    --44503222(+) CTGCAC/GGGTAG 2 -- us2k10--------
    rs1910423231,2
    --44503243(+) TTCTAC/TTGGGG 2 -- us2k10--------
    rs1155051311,2
    F--44503356(+) TGGGAG/TTTGGG 2 -- us2k11Minor allele frequency- T:0.04WA 118
    rs1157816761,2
    C,F--44503455(+) CTGCTT/CTTCTT 2 -- us2k11Minor allele frequency- C:0.03WA 118
    rs1498608431,2
    --44503723(+) CCTCCC/TGCCCA 2 -- us2k10--------
    rs1828728821,2
    --44503838(+) TGGTGC/TTGCTG 2 -- us2k10--------
    rs1474482721,2
    --44503898(+) GAGGTC/GCTTTC 2 -- us2k10--------
    rs1115159231,2
    C,F--44504359(+) CCGCCT/AACCTC 2 -- us2k11Minor allele frequency- A:0.50NA 2
    rs620242441,2
    C,F--44504393(+) CAGGCG/TTGAGC 2 -- us2k12Minor allele frequency- T:0.50NA WA 4
    rs1491752721,2
    --44504481(+) AAGGTC/TTACGG 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for SNX22 (64443914 - 64449680 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for SNX22:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv833036CNV Loss17160897
    nsv827360CNV Loss20364138

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SNX22
    DNA2.0 Custom Variant and Variant Library Synthesis for SNX22

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for SNX22 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with SNX22)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Solution structure of human sorting nexin 22. (PubMed id 17400918)1, 2, 3, 9 Song J.... Markley J.L. (Protein Sci. 2007)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Sorting out the cellular functions of sorting nexins. (PubMed id 12461558)1, 3 Worby C.A. and Dixon J.E. (Nat. Rev. Mol. Cell Biol. 2002)
    4. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    5. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    6. The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1. (PubMed id 20811636)1 Giannone R.J....Liu Y. (PLoS ONE 2010)
    7. The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment. (PubMed id 20467438)1 Arbuckle M.I....Grant S.G. (EMBO Rep. 2010)
    8. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (Nature 2005)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    10. (PubMed id )2 

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 79856 HGNC: 16315 AceView: SNX22 Ensembl:ENSG00000157734 euGenes: HUgn79856
    ECgene: SNX22 H-InvDB: SNX22

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for SNX22 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for SNX22 gene:
    Search GeneIP for patents involving SNX22

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for SNX22  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for SNX22  
     OriGene qSTAR qPCR primer pairs in human, mouse for SNX22   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for SNX22   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SNX22   OriGene Custom Protein Services for SNX22  

     
     
     Block miRNA regulation of human, mouse, rat SNX22 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing SNX22
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SNX22 Predesigned siRNA for gene silencing in human, mouse, rat SNX22
     QuantiFast Probe-based Assays in human, mouse, rat SNX22 QuantiTect SYBR Green Assays in human, mouse, rat SNX22
     Custom PCR Arrays for SNX22 Search Chromatin IP Primers for SNX22
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SNX22  Search GeneGlobe Interaction Network for SNX22
     Regulatory tfbs in SNX22 promoter
     GenScript Custom Purified and Recombinant Proteins Services for SNX22 GenScript cDNA clones with any tag delivered in your preferred vector for SNX22
     GenScript Custom Assay Services for SNX22 GenScript Custom overexpressing Cell Line Services for SNX22
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for SNX22
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     SNX22 antibodies
     SNX22 proteins
     Antibodies for SNX22
     See all of Abcam's Antibodies, Kits and Proteins for SNX22
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for SNX22
     Antibodies for SNX22
     ELISAs for SNX22
     CLIAs for SNX22



     Browse ESI BIO Cell Lines and PureStem Progenitors for SNX22
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNX22
     Browse SwitchGear 3'UTR luciferase reporter plasmids for SNX22
     SwitchGear Promoter luciferase reporter plasmids for SNX22
     Search ThermoFisher Antibodies for SNX22
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNX22
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SNX22
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SNX22
     LSBio Antibodies in human, mouse, rat for SNX22
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      SNX22 gene at Home site.
    Version: 3.12.164 25 Aug 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4