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SNX18 Gene

protein-coding   GIFtS: 50
GCID: GC05P053850

Sorting Nexin 18

(Previous name: sorting nexin associated golgi protein 1)
(Previous symbol: SNAG1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Sorting Nexin 181 2     SH3PXD3B2 3
SNAG11 2 3     SH3 And PX Domain-Containing Protein 3B2 3
Sorting Nexin Associated Golgi Protein 11 2     SH3PX22
Sorting Nexin-Associated Golgi Protein 12 3     Sorting Nexin-182

External Ids:    HGNC: 192451   Entrez Gene: 1125742   Ensembl: ENSG000001789967   UniProtKB: Q96RF03   

Export aliases for SNX18 gene to outside databases

Previous GC identifer: GC05P050787


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SNX18 Gene:
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which
is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not
contain a coiled coil region, like some family members, but contains a SH3 domain. Multiple transcript variants
encoding different isoforms have been found for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for SNX18 Gene:
SNX18 (sorting nexin 18) is a protein-coding gene. Diseases associated with SNX18 include smallpox, and malaria. GO annotations related to this gene include phosphatidylinositol binding. An important paralog of this gene is SNX9.

UniProtKB/Swiss-Prot: SNX18_HUMAN, Q96RF0
Function: Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of
mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the
cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also
clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to
membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the
GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane

Gene Wiki entry for SNX18 (SNAG1) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000005.10  NC_018916.2  NT_034772.7  
Regulatory elements:
   Regulatory transcription factor binding sites in the SNX18 gene promoter:
         Max1   NF-E2 p45   NF-E2   c-Myc   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSNX18 promoter sequence
   Search Chromatin IP Primers for SNX18

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SNX18


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q11.2   Ensembl cytogenetic band:  5q11.2   HGNC cytogenetic band: 5q11.2

SNX18 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SNX18 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P053850:  view genomic region     (about GC identifiers)

Start:
53,813,589 bp from pter      End:
53,842,416 bp from pter
Size:
28,828 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SNX18_HUMAN, Q96RF0 (See protein sequence)
Recommended Name: Sorting nexin-18  
Size: 628 amino acids; 68894 Da
Subunit: Heterodimer with SNX9. Interacts with ITCH. Interacts with dynamin, SYNJ1 and WASL. Interacts with the
AP-1 complex
Secondary accessions: B4E2B3 H7BXX3 Q05BB3 Q0VG02
Alternative splicing: 3 isoforms:  Q96RF0-1   Q96RF0-2   Q96RF0-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SNX18: NX_Q96RF0

Explore proteomics data for SNX18 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SNX18 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001096045.1  NP_001138899.1  NP_443102.2  

    ENSEMBL proteins: 
     ENSP00000370817   ENSP00000342276   ENSP00000317332  

    SNX18 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SNX: Sorting nexins

    5 InterPro protein domains:
     IPR001452 SH3_domain
     IPR019497 Sorting_nexin_WASP-bd-dom
     IPR028646 SNX18
     IPR001683 Phox
     IPR014536 Snx9_subfam

    Graphical View of Domain Structure for InterPro Entry Q96RF0

    ProtoNet protein and cluster: Q96RF0

    1 Blocks protein domain: IPB001683 Phox-like

    UniProtKB/Swiss-Prot: SNX18_HUMAN, Q96RF0
    Domain: The PX domain mediates interaction with membranes enriched in phosphatidylinositol 4,5-bisphosphate
    Similarity: Belongs to the sorting nexin family
    Similarity: Contains 1 BAR domain
    Similarity: Contains 1 PX (phox homology) domain
    Similarity: Contains 1 SH3 domain


    SNX18 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SNX18_HUMAN, Q96RF0
    Function: Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of
    mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the
    cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also
    clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to
    membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the
    GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0005546phosphatidylinositol-4,5-bisphosphate binding IDA--
    GO:0035091phosphatidylinositol binding ----
         
    SNX18 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SNX18:
     Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SNX18
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SNX18
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    miRNA
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    miRTarBase miRNAs that target SNX18:
    hsa-mir-193b-3p (MIRT041252), hsa-mir-124-3p (MIRT022134)

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    Selected qRT-PCR Assays for microRNAs that regulate SNX18 (see all 84):
    hsa-miR-124* hsa-miR-3607-3p hsa-miR-200a hsa-miR-128 hsa-miR-30d hsa-miR-502-3p hsa-miR-1304 hsa-miR-30a
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SNX18_HUMAN, Q96RF0: Endomembrane system; Peripheral membrane protein; Cytoplasmic side. Endosome membrane;
    Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
    Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localized at sites of
    endocytosis at the cell membrane. Detected on newly formed macropinosomes. Partially colocalized with clathrin
    and dynamin at the cell membrane. Transiently recruited to clathrin-coated pits at a late stage of
    clathrin-coated vesicle formation
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endosome5
    plasma membrane5
    cytosol3
    nucleus3

    Gene Ontology (GO): Selected cellular component terms (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005768endosome IBA--
    GO:0010008endosome membrane IEA--
    GO:0012505endomembrane system ----
    GO:0016023cytoplasmic membrane-bounded vesicle IDA--
    GO:0030136colocalizes with clathrin-coated vesicle IDA--

    SNX18 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SNX18
    Interactions:

        Search GeneGlobe Interaction Network for SNX18

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    Selected Interacting proteins for SNX18 (Q96RF02, 3 ENSP000003173324) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ITCHQ96J022, 3, ENSP000003639984MINT-7889719 I2D: score=2 STRING: ENSP00000363998
    SOS1Q078893, ENSP000003846754I2D: score=2 STRING: ENSP00000384675
    SOS2Q078903, ENSP000002163734I2D: score=2 STRING: ENSP00000216373
    FASLGP480233, ENSP000003566944I2D: score=1 STRING: ENSP00000356694
    KBTBD7Q8WVZ93I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000281mitotic cytokinesis IMP--
    GO:0006886intracellular protein transport IBA--
    GO:0006897endocytosis IMP--
    GO:0007067mitosis IEA--
    GO:0007154cell communication ----

    SNX18 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SNX18



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SNX18 gene (3 alternative transcripts): 
    NM_001102575.1  NM_001145427.1  NM_052870.2  

    Unigene Cluster for SNX18:

    Sorting nexin 18
    Hs.432755  [show with all ESTs]
    Unigene Representative Sequence: NM_001145427
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000381410(uc003jpi.4) ENST00000343017(uc011cqg.2) ENST00000326277(uc003jpj.4)

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate SNX18 (see all 84):
    hsa-miR-124* hsa-miR-3607-3p hsa-miR-200a hsa-miR-128 hsa-miR-30d hsa-miR-502-3p hsa-miR-1304 hsa-miR-30a
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      QuantiFast Probe-based Assays in human, mouse, rat SNX18

    Additional mRNA sequence: 

    AF395536.1 AK022059.1 AK304195.1 BC060791.1 BC067860.1 BC117218.1 BC117220.1 

    5 DOTS entries:

    DT.311110  DT.97813204  DT.101960582  DT.40260251  DT.102827050 

    Selected AceView cDNA sequences (see all 76):

    AA668545 BX107481 AA825651 AW386094 BU742437 BQ022586 AA504492 AI272193 
    BX472996 AA601509 AA897576 CB143831 BC067860 CB124515 AA865369 AI681573 
    CB132834 BF439089 BE351030 BC060791 BM727909 AI335241 AU120810 AK057122 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SNX18 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTATCTTTT
    SNX18 Expression
    About this image

    SNX18 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SNX18 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.432755
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SNX18 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Snx181 , 5 sorting nexin 181, 5 90.46(n)1
    96.91(a)1
      13 (64.00 cM)5
    1706251  NM_130796.41  NP_570614.21 
     1135921805 
    chicken
    (Gallus gallus)
    Aves SNX181 sorting nexin 18 84.94(n)
    87.52(a)
      768969  XM_001231593.3  XP_001231594.1 
    lizard
    (Anolis carolinensis)
    Reptilia SNX186
    sorting nexin 18
    68(a)
    1 ↔ 1
    2(2871710-2890970)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.32902 Transcribed sequence with moderate similarity to protein more 82.66(n)    141999017 
    zebrafish
    (Danio rerio)
    Actinopterygii snx18a1 sorting nexin 18a 70.55(n)
    76.68(a)
      562372  NM_001100006.1  NP_001093476.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta SH3PX11 SH3PX1 54.02(n)
    40.64(a)
      39136  NM_140091.4  NP_648348.1 
    worm
    (Caenorhabditis elegans)
    Secernentea lst-46
    Protein LST-4, isoform a
    26(a)
    1 → many
    IV(14061005-14069854) WBGene00003086


    ENSEMBL Gene Tree for SNX18 (if available)
    TreeFam Gene Tree for SNX18 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SNX18 gene
    SNX92  SNX332  
    4 SIMAP similar genes for SNX18 using alignment to 1 protein entry:     SNX18_HUMAN:
    SH3GL1    SH3GL2    SNX33    SNX9

    SNX18 for paralogs           About GeneDecksing


    Selected Pseudogenes.org Pseudogenes for SNX18 (see all 40)
    PGOHUM00000248291 PGOHUM00000248504 PGOHUM00000234874 PGOHUM00000235014 PGOHUM00000234545


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SNX18 (see all 682)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1380930221,2
    C--53811647(+) GTTTT-/CCCTGC 3 -- us2k10--------
    rs1906061591,2
    --53811948(+) TAAACA/GAACAG 3 -- us2k10--------
    rs749335561,2
    C--53811960(+) AGGGGC/TGAAAC 3 -- us2k13Minor allele frequency- T:0.19NA WA 240
    rs797043851,2
    C--53812031(+) TAGAGG/ATTTAG 3 -- us2k12Minor allele frequency- A:0.05CSA WA 120
    rs357873641,2
    C,F--53812076(+) TGTTGG/CCATTG 3 -- us2k17Minor allele frequency- C:0.21WA NA CSA EA 365
    rs126582531,2
    C,A,H--53812093(+) AATGAG/TCCCTG 3 -- us2k110Minor allele frequency- T:0.13WA NA CSA EA 371
    rs1147958281,2
    C,F--53812125(+) AAAACC/TCAGAA 3 -- us2k11Minor allele frequency- T:0.04WA 118
    rs1428647911,2
    --53812186(+) TTTTGC/TATTAG 3 -- us2k10--------
    rs1506493711,2
    C--53812233(+) TTGTGA/TTTTTG 3 -- us2k10--------
    rs1831748991,2
    --53812261(+) ACCACA/GGCCCT 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for SNX18 (53813589 - 53842416 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for SNX18:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv26784CNV Loss19812545
    esv34152CNV Loss18971310
    nsv880713CNV Gain21882294
    dgv6067n71CNV Gain21882294
    dgv6069n71CNV Gain21882294
    nsv881404CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SNX18
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    3 diseases for SNX18:    
    About MalaCards
    smallpox    malaria    neuronitis


    SNX18 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SNX18

    Export disorders for SNX18 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SNX18 gene, integrated from 10 sources (see all 30):
    (articles sorted by number of sources associating them with SNX18)
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    1. SNX18 is an SNX9 paralog that acts as a membrane tubulator in AP-1- positive endosomal trafficking. (PubMed id 18411244)1, 2, 9 Haberg K.... Carlsson S.R. (J. Cell Sci. 2008)
    2. A proteomic screen reveals novel Fas ligand interacting proteins within nervous system Schwann cells. (PubMed id 17761170)1, 3, 9 Thornhill P.B....Desbarats J. (FEBS Lett. 2007)
    3. SNX9, SNX18 and SNX33 are required for progression through and completion of mitosis. (PubMed id 22718350)1, 2 Ma M.P. and Chircop M. (J. Cell. Sci. 2012)
    4. SNX18 shares a redundant role with SNX9 and modulates endocytic trafficking at the plasma membrane. (PubMed id 20427313)1, 2 Park J....Chang S. (J. Cell Sci. 2010)
    5. The E3 ubiquitin ligase Itch regulates sorting nexin 9 through an unconventional substrate recognition domain. (PubMed id 20491914)1, 2 Baumann C.... Levy F. (FEBS J. 2010)
    6. The Phox (PX) domain proteins and membrane traffic. (PubMed id 16782399)1, 3 Seet L.F. and Hong W. (Biochim. Biophys. Acta 2006)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    8. Membrane remodeling by the PX-BAR protein SNX18 promotes autophagosome formation. (PubMed id 23878278)1 KnA ( 2013)
    9. Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. (PubMed id 24255178)1 Couzens A.L....Gingras A.C. (Sci Signal 2013)
    10. Genome-wide association study of antibody response to smallpox vaccine. (PubMed id 22542470)1 Ovsyannikova I.G....Poland G.A. (Vaccine 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 112574 HGNC: 19245 AceView: SNAG1 Ensembl:ENSG00000178996 euGenes: HUgn112574
    ECgene: SNX18 H-InvDB: SNX18

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SNX18 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SNX18 gene:
    Search GeneIP for patents involving SNX18

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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