External Ids for SNX16 Gene
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. The function of this protein has not been determined. This gene results in three transcript variants encoding two distinct isoforms. [provided by RefSeq, Jul 2008]
GeneCards Summary for SNX16 Gene
SNX16 (Sorting Nexin 16) is a Protein Coding gene. Diseases associated with SNX16 include low tension glaucoma. GO annotations related to this gene include identical protein binding and phosphatidylinositol binding.
UniProtKB/Swiss-Prot for SNX16 Gene
May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling. Plays a role in intracellular transport of vesicular stomatitis virus nucleocapsids from the endosome to the cytoplasm.