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SNX15 Gene

protein-coding   GIFtS: 54
GCID: GC11P064794

Sorting Nexin 15

  See SNX15-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Sorting Nexin 151 2
HSAF0014352
Clone Iota Unknown Protein2
Sorting Nexin-152

External Ids:    HGNC: 149781   Entrez Gene: 299072   Ensembl: ENSG000001100257   OMIM: 6059645   UniProtKB: Q9NRS63   

Export aliases for SNX15 gene to outside databases

Previous GC identifers: GC11P067310 GC11P066463 GC11P065031 GC11P064557 GC11P064538 GC11P064552 GC11P064782 GC11P061121


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SNX15 Gene:
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which
is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene
results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature
subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of
insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma
membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript
variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like
2 (ARL2) gene. (provided by RefSeq, Dec 2010)

GeneCards Summary for SNX15 Gene:
SNX15 (sorting nexin 15) is a protein-coding gene. Diseases associated with SNX15 include mitochondrial disorders. GO annotations related to this gene include protein transporter activity and phosphatidylinositol binding. An important paralog of this gene is RPS6KL1.

UniProtKB/Swiss-Prot: SNX15_HUMAN, Q9NRS6
Function: May be involved in several stages of intracellular trafficking. Overexpression of SNX15 disrupts the
normal trafficking of proteins from the plasma membrane to recycling endosomes or the TGN

Gene Wiki entry for SNX15 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NC_018922.2  NT_167190.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SNX15 gene promoter:
         STAT1   Tal-1   p53   MAZR   Brachyury   SREBP-1c   E47   SREBP-1b   AREB6   SREBP-1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSNX15 promoter sequence
   Search Chromatin IP Primers for SNX15

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SNX15


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q12   Ensembl cytogenetic band:  11q13.1   HGNC cytogenetic band: 11q12

SNX15 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SNX15 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P064794:  view genomic region     (about GC identifiers)

Start:
64,794,880 bp from pter      End:
64,808,044 bp from pter
Size:
13,165 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SNX15_HUMAN, Q9NRS6 (See protein sequence)
Recommended Name: Sorting nexin-15  
Size: 342 amino acids; 38291 Da
Subunit: Homodimer. Interacts with SNX1, SNX2 and SNX4
Secondary accessions: Q9NRS5
Alternative splicing: 2 isoforms:  Q9NRS6-1   Q9NRS6-2   

Explore the universe of human proteins at neXtProt for SNX15: NX_Q9NRS6

Explore proteomics data for SNX15 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SNX15 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_037438.2  NP_680086.2  

    ENSEMBL proteins: 
     ENSP00000366452   ENSP00000434778   ENSP00000437277   ENSP00000431690   ENSP00000316410  
     ENSP00000436023  

    SNX15 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SNX: Sorting nexins

    3 InterPro protein domains:
     IPR007330 MIT
     IPR001683 Phox
     IPR028665 SNX15

    Graphical View of Domain Structure for InterPro Entry Q9NRS6

    ProtoNet protein and cluster: Q9NRS6

    2 Blocks protein domains:
    IPB001683 Phox-like
    IPB007330 MIT


    UniProtKB/Swiss-Prot: SNX15_HUMAN, Q9NRS6
    Domain: The PX domain mediates interaction with membranes enriched in phosphatidylinositol 3-phosphate (By
    similarity)
    Similarity: Belongs to the sorting nexin family
    Similarity: Contains 1 MIT domain
    Similarity: Contains 1 PX (phox homology) domain


    Find genes that share domains with SNX15           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SNX15_HUMAN, Q9NRS6
    Function: May be involved in several stages of intracellular trafficking. Overexpression of SNX15 disrupts the
    normal trafficking of proteins from the plasma membrane to recycling endosomes or the TGN

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008565protein transporter activity ----
    GO:0035091phosphatidylinositol binding IEA--
         
    Find genes that share ontologies with SNX15           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SNX15
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SNX15

    miRNA
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    miRTarBase miRNAs that target SNX15:
    hsa-mir-16-5p (MIRT001477)

    Block miRNA regulation of human, mouse, rat SNX15 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SNX15 (see all 10):
    hsa-miR-34c-5p hsa-miR-449b hsa-miR-513a-3p hsa-miR-133b hsa-miR-449a hsa-miR-34a hsa-miR-935 hsa-miR-133a
    SwitchGear 3'UTR luciferase reporter plasmidSNX15 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SNX15

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNX15


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SNX15_HUMAN, Q9NRS6: Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle
    membrane; Peripheral membrane protein; Cytoplasmic side
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    nucleus4
    endosome2
    mitochondrion1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005829cytosol NAS11085978
    GO:0016020membrane NAS11085978
    GO:0030659cytoplasmic vesicle membrane IEA--

    Find genes that share ontologies with SNX15           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SNX15 About    
    See pathways by source

    SuperPathContained pathways About
    1PDGFR-beta signaling pathway
    PDGFR-beta signaling pathway


    1 BioSystems Pathway for SNX15
        PDGFR-beta signaling pathway



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SNX15
    Interactions:

        Search GeneGlobe Interaction Network for SNX15

    4 Interacting proteins for SNX15 (Q9NRS62, 3) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RABAC1Q9UI142, 3MINT-67772 I2D: score=5 
    TMEM66Q96BY92, 3MINT-64352 I2D: score=4 
    REEP6Q96HR93I2D: score=1 
    RTN4Q9NQC33I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006886intracellular protein transport NAS11085978
    GO:0007154cell communication ----

    Find genes that share ontologies with SNX15           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SNX15



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SNX15 gene (2 alternative transcripts): 
    NM_013306.4  NM_147777.3  

    Unigene Cluster for SNX15:

    Sorting nexin 15
    Hs.80132  [show with all ESTs]
    Unigene Representative Sequence: NR_037650
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000377244 ENST00000529673 ENST00000534637 ENST00000524831 ENST00000352068
    ENST00000526702 ENST00000525648
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate SNX15 (see all 10):
    hsa-miR-34c-5p hsa-miR-449b hsa-miR-513a-3p hsa-miR-133b hsa-miR-449a hsa-miR-34a hsa-miR-935 hsa-miR-133a
    SwitchGear 3'UTR luciferase reporter plasmidSNX15 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector (see all 2): SNX15 (NM_013306)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SNX15
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNX15
    Primer
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    OriGene qPCR primer pairs and template standards for SNX15
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SNX15
      QuantiTect SYBR Green Assays in human, mouse, rat SNX15
      QuantiFast Probe-based Assays in human, mouse, rat SNX15

    Additional mRNA sequence: 

    AF001435.1 AF175267.2 AF175268.1 AK315034.1 AK315642.1 BC009897.2 BC012767.2 BC014520.2 
    BT006631.1 NR_037650.1 

    7 DOTS entries:

    DT.113150  DT.100828277  DT.100828278  DT.92425265  DT.100828276  DT.95296513  DT.102825943 

    Selected AceView cDNA sequences (see all 324):

    BC002530 CB156380 AA333945 BM695030 CB109435 NM_147777 AW297877 NM_013306 
    BM853836 BU730115 AI631767 CR619183 AJ346501 BE140389 CR595019 BC012767 
    BE279801 CR614003 T29292 AA325070 BX111746 BC014520 BQ957603 BQ691172 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for SNX15    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13
    SP1:                                                                                                            
    SP2:                                -                                                                           
    SP3:                                -     -     -                                                               
    SP4:                                                                                                            
    SP5:                                                                                                            


    ECgene alternative splicing isoforms for SNX15

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SNX15 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTGTCTGTC
    SNX15 Expression
    About this image

    SNX15 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SNX15 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.80132

    UniProtKB/Swiss-Prot: SNX15_HUMAN, Q9NRS6
    Tissue specificity: Widely expressed

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SNX15 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Snx151 , 5 sorting nexin 151, 5 84.72(n)1
    88.1(a)1
      19 (4.34 cM)5
    690241  NM_026912.11  NP_081188.11 
     61193995 
    lizard
    (Anolis carolinensis)
    Reptilia SNX156
    sorting nexin 15
    55(a)
    1 ↔ 1
    GL344077.1(58242-69328)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia snx151 sorting nexin 15 55.27(n)
    53.23(a)
      734054  NM_001100197.1  NP_001093667.1 
    zebrafish
    (Danio rerio)
    Actinopterygii snx151 sorting nexin 15 58.37(n)
    54.62(a)
      393352  NM_001111237.1  NP_001104707.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG71566
    --
    10(a)
    1 → many
    3R(14065142-14067906)
    worm
    (Caenorhabditis elegans)
    Secernentea rskd-16
    Protein RSKD-1, isoform a
    7(a)
    1 → many
    V(12284058-12288617) WBGene00010096


    ENSEMBL Gene Tree for SNX15 (if available)
    TreeFam Gene Tree for SNX15 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SNX15 gene
    RPS6KL12  RPS6KC12  
    1 SIMAP similar gene for SNX15 using alignment to 7 protein entries:     SNX15_HUMAN (see all proteins):
    RPS6KC1

    Find genes that share paralogs with SNX15           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SNX15 (see all 355)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1112725491,2
    C--64712744(+) TGTGA-/CCACT 
            
    CCAAC
    2 -- us2k11Minor allele frequency- CCACT:0.00CSA 2
    rs171465891,2
    C,F,H--64712781(+) TATGTC/TAGAGT 2 -- us2k115Minor allele frequency- T:0.12NA NS EA WA CSA 929
    rs1400681001,2
    --64712809(+) TGTAGA/GTGCTG 2 -- us2k10--------
    rs710496801,2
    C,F--64712865(-) ATCTC-/A/ATCT
    C
    /GTCTCA
    AAAAA
    4 -- us2k1 cds12NA 4
    rs108975431,2
    C,A--64712870(+) TGAGAC/TGGAGT 2 -- us2k11Minor allele frequency- T:0.50NA 2
    rs1864034741,2
    C--64713002(+) GCACCC/TGCCAC 2 -- us2k10--------
    rs1118684371,2
    C,F--64713010(+) CACCAC/TGCCCA 2 -- us2k11Minor allele frequency- T:0.50WA 2
    rs3708290251,2
    C--64713042(+) GAGAC-/GGGGGT 2 -- us2k10--------
    rs1884624861,2
    --64713251(+) CACGCA/GTCTGC 2 -- us2k10--------
    rs5023331,2
    C,F,O,H--64713330(-) CCTGAC/TCTCAG 2 -- us2k127Minor allele frequency- N:0.00MN EA NA NS WA CSA 2916

    HapMap Linkage Disequilibrium report for SNX15 (64794880 - 64808044 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for SNX15:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv1174n71CNV Loss21882294
    nsv526181CNV Gain19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SNX15
    DNA2.0 Custom Variant and Variant Library Synthesis for SNX15

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 605964    OMIM disorders: --

    1 disease for SNX15:    
    About MalaCards
    mitochondrial disorders

    1 disease from the University of Copenhagen DISEASES database for SNX15:
    Paraplegia

    Find genes that share disorders with SNX15           About GenesLikeMe


    Export disorders for SNX15 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SNX15 gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with SNX15)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Identification and characterization of snx15, a novel sorting nexin involved in protein trafficking. (PubMed id 11085978)1, 2 Phillips S.A.... Haft C.R. (J. Biol. Chem. 2001)
    3. Overexpression of a novel sorting nexin, SNX15, affects endosome morphology and protein trafficking. (PubMed id 11208079)1, 3 Barr V.A....Haft C.R. (Traffic 2000)
    4. A clinical, genetic and candidate gene study of Silver syndrome, a complicated form of hereditary spastic paraplegia. (PubMed id 15372247)1, 9 Warner T.T....Crosby A.H. (J. Neurol. 2004)
    5. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (Nat. Methods 2013)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    8. Identification of rare DNA variants in mitochondrial disorders with improved array-based sequencing. (PubMed id 20843780)1 Wang W.... Scharfe C. (Nucleic Acids Res. 2011)
    9. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)
    10. Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6. (PubMed id 19738201)1 Humphries J.D....Humphries M.J. (Sci Signal 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 29907 HGNC: 14978 AceView: ARL2andSNX15 Ensembl:ENSG00000110025 euGenes: HUgn29907
    ECgene: SNX15 H-InvDB: SNX15

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SNX15 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SNX15 gene:
    Search GeneIP for patents involving SNX15

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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